Hyery Kim, MD¹, Jung Yoon Choi^2,3*, Sung Han Kang, MD^1*, Kyung Nam Koh, MD, MS^1*, Kyung Taek Hong, MD^3,4, Hee Young Ju, MD^5*, Keon Hee Yoo, MD, PhD^5*, Sunmin Yun^6*, Yoomi Park^6*, Ju Han Kim, MD, PhD^6*, Hyoung Jin Kang, MD, PhD^3,7 and Ho Joon Im, MD, PhD^1*

¹Department of Pediatrics, Asan Medical Center Children’s Hospital, University of Ulsan College of Medicine, Seoul, Korea, Republic of (South)
²Department of Pediatrics, Seoul National University College of Medicine, Seoul, South Korea
³Seoul National University Cancer Research Institute, Seoul, Korea, Republic of (South)
⁴Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea, Republic of (South)
⁵Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of (South)
⁶Seoul National University Biomedical Informatics (SNUBI), Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul, Korea, Republic of (South)
⁷Department of Pediatrics, Seoul National University College of Medicine and Hospital, Seoul, Korea, Republic of (South)

Luke Maese, DO¹, Mignon L. Loh, MD², Mi Rim Choi^3*, Tong Lin^3*, Etsuko Aoki^3*, Shirali Agarwal^3*, Vijayalakshmi Chandrasekaran^4*, Yali Liang^4*, Suzette Girgis^4*, Cuiping Chen^3*, Robert Iannone^4*, Lewis B. Silverman, MD⁵, Elizabeth A. Raetz^6* and Rachel E. Rau^2*

¹University of Utah, Primary Children’s Hospital, Salt Lake City, UT
²Ben Towne Center for Childhood Cancer Research, Seattle Children’s Hospital, Seattle, WA
³Jazz Pharmaceuticals, Palo Alto, CA
⁴Jazz Pharmaceuticals, Philadelphia, PA
⁵Dana-Farber Cancer Institute, Boston Children’s Hospital, Boston, MA
⁶New York University Langone Medical Center, New York, NY

Anjali S. Advani, MD¹, Anna B Moseley, MS^2,3*, Kristen M. O'Dwyer, MD⁴, Brent L. Wood, MD, PhD⁵, Jae H. Park, MD⁶, Matthew J. Wieduwilt, MD^7*, Deepa Jeyakumar, MD⁸, George Yaghmour, MD⁹, Ehab L. Atallah, MD¹⁰, Aaron T. Gerds, MD, MS¹¹, Susan M. O'Brien¹², Jane L. Liesveld, MD¹³, Megan Othus, PhD^3,14, Mark R. Litzow, MD¹⁵, Richard M Stone, MD¹⁶, Elad Sharon, MD, MPH^17*, Cecilia C.S. Yeung, MD², Jerald P. Radich, MD¹⁸ and Harry P. Erba, MD, PhD¹⁹

¹Leukemia Program, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
²Fred Hutchinson Cancer Center, Seattle, WA
³SWOG Statistics and Data Mangement Center, Seattle, WA
⁴University of Rochester, Rochester, NY
⁵Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA
⁶Memorial Sloan Kettering Cancer Center, New York, NY
⁷Atrium Health Wake Forest Baptist, Winston Salem, NC
⁸Hematopoietic Stem Cell Transplantation and Cellular Therapy Program, Division of Hematology/Oncology, Department of Medicine, University of California Irvine, Orange, CA
⁹USC Norris Comprehensive Cancer Center, Los Angeles, CA
¹⁰Division of Hematology/Oncology, Medical College of Wisconsin, Milwaukee, WI
¹¹Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
¹²Chao Family Comprehensive Cancer Center, University of California, Irvine, Orange, CA
¹³James P. Wilmot Cancer Center, University of Rochester Medical Center, Rochester, NY
¹⁴Public Health Science Division, Fred Hutchinson Cancer Center, Seattle, WA
¹⁵Division of Hematology, Mayo Clinic, Rochester, MN
¹⁶Dana-Farber Cancer Institute, Boston, MA
¹⁷NCI Cancer Therapy Evaluation program (CTEP), Bethesda, MD
¹⁸Translational Sciences & Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA
¹⁹Duke Cancer Institute, Durham, NC

Jayastu Senapati, MD, MBBS, DM¹, Elias Jabbour², Nicholas J. Short, MD¹, Guilin Tang, MD PhD^3*, Fadi G. Haddad, MD^1*, Nitin Jain, MD¹, Ghayas C. Issa⁴, Tapan M. Kadia, MD¹, Naval Daver, MD¹, Alessandra Ferrajoli, MD¹, Monica Kwari, BSN^5*, Guillermo Garcia-Manero, MD^1*, Guillermo Montalban-Bravo, MD¹, Patrice Eric Nasnas, MD^6*, Naveen Pemmaraju, MD¹, Rebecca Garris^1*, Farhad Ravandi, MD, MBBS¹ and Hagop M. Kantarjian, MD¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²University of Texas M.D. Anderson Cancer Ctr., Houston, TX
³Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX
⁴The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Leukemia, MD Anderson Cancer Center, Houston, TX
⁶Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Han-Yu Cao^1*, Lu-Lu Chen^2*, Chao-Ling Wan^3*, Xiao-Hui Hu^4*, Bing Wu^5*, Li Yang^6*, Li Wang^7*, Yang Zhang^8*, De-Pei Wu⁹, Hai-Ping Dai^4*, Hao Zhang^2* and Shengli Xue^4*

¹The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, Suzhou, China
²Affiliated Hospital of Jining Medical University, Jining, China
³Department of Hematology, The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, Suzhou, China
⁴The First Affiliated Hospital of Soochow University, Suzhou, China
⁵Suzhou Hospital of Traditional Chinese Medicine, Suzhou, China
⁶Department of Hematology, Affiliated Hospital of Nantong University, Nantong, China
⁷Huai'an Second People's Hospital, Huai'an, China
⁸Canglang Hospital of Suzhou, Suzhou, China
⁹Department of Hematology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China

Lars Fransecky^1*, Walter Fiedler, MD², Christoph Röllig, MD, MSc^3*, Tim Sauer, MD^4*, Simon Raffel, MD^4*, Winfried Alsdorf^5*, Lisa Heberling^6*, Kumaran Nagarajan^7*, Britta Steer^7*, Philipp Nakov, MD^8*, Björn Steffen, MD^9*, Dorothee Deckbar^10*, Sonja Bendig^11*, Lorenz Bastian^12*, Martin Neumann^13*, Monika Brueggemann, PhD^14*, Nicola Goekbuget, MD¹⁵ and Claudia D Baldus, MD^1*

¹Department of Internal Medicine II (Hematology/Oncology), University Hospital Schleswig-Holstein Campus Kiel, Kiel, Germany
²University Hospital Hamburg-Eppendorf, Hamburg, DEU
³Department of Internal Medicine I, University Hospital Dresden, Dresden, Germany
⁴Heidelberg University Hospital, Heidelberg, Germany
⁵Universitaetsklinikum Hamburg Eppendorf, Hamburg, Germany
⁶University Hospital Dresden, TU Dresden, Germany, Dresden, Germany
⁷UKSH Campus Kiel, Kiel, Germany
⁸University Hospital Schleswig Holstein Campus Kiel, Kiel, Germany
⁹Department of Internal Medicine II, Hematology and Oncology, Goethe University Hospital Frankfurt, Frankfurt, Germany
¹⁰Goethe University Frankfurt, Frankfurt, Germany
¹¹University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, DEU
¹²CATCH-ALL, UKSH Campus Kiel, Kiel, Germany
¹³Medical Department II, University Cancer Center Schleswig-Holstein, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany
¹⁴University Hospital Schleswig-Holstein, Kiel, DEU
¹⁵Goethe University Hospital, Frankfurt, Germany

Carlos Plaza, MD^1*, Brenner Sabado, MD^2*, Teodoro Chisesi, MD^3*, Manuel A Granja, MD^4*, Andrés Orquera, MD^5*, Maria Augusta Pacheco, MD^6*, Jairo Manuel Quiñonez, MD^7*, Maria Del Carmen Trujillo, MD^8*, Danilo A Navarrete, MD^9*, Lorena Sanchez, MD^10*, Johanna Ramírez, MD^11* and Jorge Oliveros-Alvear, MD, MMSc^2,12

¹Hematology Department, SOLCA Guayaquil, Guayaquil, Guayas, Ecuador
²Hematology Department, Hospital Luis Vernaza, Guayaqul, Guayas, Ecuador
³HEMATOLOGY, FUNDACION ANGELA SERRA, GUAYAQUIL, GUAYAS, ECU
⁴Hematology Department, Hospital de Especialidades Carlos Andrade Marín, QUITO, PICHINCHA, ECU
⁵Hematology Department, Hospital de Especilidades Carlos Andrade Marín, QUITO, PICHINCHA, Ecuador
⁶Hematology Department, SOLCA Cuenca, Cuenca, Azuay, Ecuador
⁷Medicina Interna, Centro de Especialidades Médicas INRHED, samborondon, Guayas, Ecuador
⁸Hematology Department, Hospital Eugenio Espejo, Quito, Pichincha, ECU
⁹Hematology Department, SOLCA MANABI, PORTOVIEJO, MANABÍ, Ecuador
¹⁰HEMATOLOGY DEPARTMENT, HOSPITAL ABEL GILBERT PONTON, GUAYAQUIL, GUAYAQS, ECU
¹¹Hospital de Especilidades Teodoro Mandonado Carbo, Guayaquil, Guayas, Ecuador
¹²Facultad de Medicina, Universidad de Guayaquil, Guayaqul, Ecuador

Ting Zhang^1*, Kaibo Zhu^2*, Cai Zihong^3*, Ren Lin^2,4*, Qifa Liu, MD⁵ and Hongsheng Zhou^6,7*

¹zhangtashley@hotmail.com, Guangzhou, China
²Nanfang Hospital, Guangzhou, China
³Nanfang Hospital, Southern Medical University,, Guangzhou, China
⁴lansinglinren@163.com, Guangzhou, China
⁵Department of Hematology, Nanfang Hospital, Southern medical university CN, Guangzhou, China
⁶Nanfang Hospital, Southern Medical University, Guangzhou, China
⁷Nanfang Hospital, Southern Medical University, Guangzhou, CHN

Libai Chen, MD^*, Huiyan Yang^*, Lei Zhang^*, Yongsheng Ruan, MD, Jianyun Wen^* and Xuedong Wu, MD^*

Department of Pediatrics, Nanfang Hospital, Southern Medical University, Guangzhou, China

Yan-yan Li^1*, Hai-xia Zhou^2*, Si-man Huang^2*, Chao-Ling Wan^2*, Ming-zhu Xu^2*, Wen-jie Gong^2*, Chong-Sheng Qian^2*, De-pei Wu³, Haiping Dai^2* and Sheng-Li Xue^4*

¹The First Affiliated Hospital of Soochow University, Suzhou, AL, China
²The First Affiliated Hospital of Soochow University, Suzhou, China
³National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China, Suzhou, China
⁴Department of Hematology, The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, National Clinical Research Center for Hematologic Diseases, Suzhou, China

Monia Lunghi, MD, PhD^1*, Francesca Kaiser, MD^2*, Deborah Cardinali, Bachelor in Science^2*, Claudia Basilico, MD^3*, Marzia Defina, MD^4*, Sara Mastaglio, MD^5*, Lazzarotto Davide, MD^6*, Prassede Salutari, MD^7*, Matteo Piccini, MD^8*, Valeria Cardinali, MD^9*, Antonio Pierini, MD, PhD^10*, Nicola Fracchiolla, MD^11*, Federica Di Biase, MD^12*, Mario Annunziata, MD^13*, Mariangela Di Trani, Bachelor in Science^2*, Felicetto Ferrara, MD^14*, Giovanni Pizzolo, MD^15*, Robin Foà, MD^2* and Sabina Chiaretti, MD, PhD¹⁶

¹Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy
²Division of Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy
³Divisione di Ematologia, Ospedale di Circolo di Varese e Fondazione Macchi, ASST Sette Laghi, Varese, Italy
⁴Hematology, Azienda Ospedaliera Universitaria Senese, Siena, Italy
⁵Hematology and Bone Marrow Transplant, Unit San Raffaele Scientific Institute, Milan, Italy
⁶Clinica Ematologica e Centro Trapianti, Azienda Sanitaria Universitaria Friuli Centrale, Udine, Italy
⁷Department of Hematology, Ospedale Civile Spirito Santo, Pescara, Pescara, Italy
⁸SOD Ematologia, Università di Firenze, AOU Careggi, Firenze, Italy
⁹Università Di Perugia, Periglia, ITA
¹⁰Department of Medicine and Surgery, Division of Hematology and Clinical Immunology, University of Perugia, Perugia, Italy
¹¹Hematology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico di Milano, Milano, Italy
¹²Department of Molecular Biotechnology and Health Sciences, Division of Hematology, University of Torino, Torino, Italy
¹³Azienda Ospedaliera Di Rilievo Nazionale Antonio Cardarelli, Napoli, ITA
¹⁴Divisione di Ematologia, Ospedale Cardarelli, Napoli, Italy
¹⁵Department of Medicine, Hematology section, University of Verona, Verona, ITA
¹⁶Division of Hematology, Department of Translational and Precision Medicine, Division of Hematology, Rome, Italy

Trevor Jamison, MD^1,2*, Hagop M. Kantarjian, MD³, Shilpa Paul, PharmD^3*, Branko Cuglievan⁴, David McCall, MD^5*, Nitin Jain, MD³, Fadi G. Haddad, MD^3*, Kayleigh R. Marx, PharmD^3*, Caitlin R Rausch, PharmD^3*, J. Michael Savoy, PharmD^4*, Lewis Nasr^3*, Cedric Nasnas^3*, Marianne Zoghbi^3*, Rebecca Garris^3*, Farhad Ravandi, MD, MBBS³, Marina Y. Konopleva³, Elias Jabbour³ and Nicholas J. Short, MD³

¹Department of Medicine, Baylor College of Medicine, Missouri City, TX
²Division of Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Division of Pediatrics, MD Anderson, Houston, TX

Marlise R. Luskin, MD¹, Shai Shimony, MD^2*, Julia Keating, MS^3*, Yael Flamand, MS^4*, Jacqueline S. Garcia, MD², Rebecca Leonard^2*, Thomas Reardon^4*, Taylor Robertson^4*, Chase M Weizer^4*, Ilene Galinsky, ANP², Donna S. Neuberg, ScD³, Richard M Stone, MD⁴, Eric S. Winer, MD⁴, Anthony G. Letai⁴, Mark Alan Murakami, MD, MA, MMSc⁴ and Daniel J. DeAngelo⁴

¹Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
²Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
³Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
⁴Dana-Farber Cancer Institute, Boston, MA

Mark Blaine Geyer, MD^1,2, John Mascarenhas, MD^3*, Marissa Smith^4*, Shakira Pascual^2*, Anmol Shah^2*, Michael R. Silvestrone^2*, Tina Czaplinska^3*, Kathryn Johnson, DNP, MSc, FNP-BC^5*, Meghan C. Thompson, MD⁶ and Jae H. Park, MD^6,7

¹Department of Medicine, Cell Therapy Service, Memorial Sloan Kettering Cancer Center, New York, NY
²Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
³Department of Medicine, Division of Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
⁴Department of Nursing, Memorial Sloan Kettering Cancer Center, New York, NY
⁵Department of Nursing, Icahn School of Medicine at Mount Sinai, New York, NY
⁶Memorial Sloan Kettering Cancer Center, New York, NY
⁷Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY

Nora Philipp^1,2*, Anetta Marcinek, M.Sc.^1,2*, Gerulf Hänel, Ph.D.^1,2*, Daniel Nixdorf, MSc^1,2*, Veit L. Buecklein, MD^1,3* and Marion Subklewe, MD^1,2,4

¹Laboratory for Translational Cancer Immunology, Gene Center, LMU Munich, Munich, Germany
²Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany
³Department of Medicine III, University Hospital, LMU Munich, Munich, Germany
⁴German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany

Jessica T. Leonard, MD¹, Rachel J. Cook, MD², Laura F. Newell, MD³, Arpita Gandhi, MD⁴, Ronan T. Swords, MD, PhD, FRCP, FRCPath⁵, Christopher A. Eide^3*, Brandon Hayes-Lattin, MD⁶, Kara Johnson^7*, Elie Traer, MD, PhD⁸, Stephen E. Kurtz^3*, Jennifer N. Saultz, DO³, Cristina Tognon, PhD^7*, Jeffrey W Tyner, PhD³ and Curtis A Lachowiez, MD⁹

¹Department of Hematology & Medical Oncology, Oregon Health and Science University, Portland, OR
²Oregon Health and Science University, Portland, OR
³Knight Cancer Institute, Oregon Health & Science University, Portland, OR
⁴Division of Hematology/Medical Oncology, Knight Cancer Institute, Oregon Health and Science University, Portland, OR
⁵Knight Cancer Institute, Oregon Health and Science University, Portland, OR
⁶Knight Cancer Institute, Oregon Health Science University, Portland, OR
⁷Oregon Health & Science University, Portland, OR
⁸Knight Cancer Institute, Oregon Health & Sciences University, Portland, OR
⁹Knight Cancer Institute, Oregon Health & Science University, Houston, TX