Jeremy T. Baeten, PhD^1*, Irenaeus C.C. Chan, MSc^2*, Lea Moukarzel, MD^3*, Amber C. Carter, BS^2*, Minal Patel, BA^3*, Konrad H. Stopsack, MD, MPH^4*, Paul Pharoah, PhD^5*, James Brenton, MD/PhD^6*, Bob T Li^3*, Wassim Abida, MD^3*, Alison M. Schram, MD^3*, Karen Cadoo, MD^7*, Britta Weigelt, PhD^3*, Carlos Cruchaga, PhD^8*, Howard Scher, MD^3*, Ross L Levine, MD⁹, Elli Papaemmanuil, PhD¹⁰, Daniel C. Link, MD² and Kelly L. Bolton, MD²

¹Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO
²Division of Oncology, Department of Medicine, Washington University School of Medicine, St. Louis, MO
³Memorial Sloan Kettering Cancer Center, New York, NY
⁴School of Public Health, Harvard University, Boston, MA
⁵Cedars-Sinai Hospital, Los Angeles, CA
⁶University of Cambridge, Cambridge, United Kingdom
⁷St. James Hospital, Dublin, Ireland
⁸Washington University School of Medicine, Saint Louis, MO
⁹Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁰Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY

Yang Li^1*, Chen Jia^2*, Ting Sun^2*, Renchi Yang, MD³ and Lei Zhang, MD⁴

¹Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, AL, China
²Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
³Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China
⁴State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Tianjin Key Laboratory of Gene Therapy for Blood Diseases, CAMS Key Laboratory of Gene Therapy for Blood Diseases, Tianjin, China

Christopher Maximilian Arends^1*, Klara Kopp^1*, Natalia Estrada-Barreras^1*, Raphael Hablesreiter^1*, Nicole Concin^2*, Ute Moll^3*, Robert Zeilinger^4*, Wolfgang Schmitt^5*, Jalid Sehouli^6*, Hagen Kulbe^6,7*, Isabelle Ray-Coquard^8*, Alain Zeimet^2*, Francesco Raspagliesi^2*, Claudio Zamagni^9*, Ignace Vergote^10*, Domenica Lorusso^11*, Lars Bullinger^12,13, Elena Ioana Braicu^6,14* and Frederik Damm^1,13*

¹Department of Hematology, Oncology and Cancer Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany
²Department of Obstetrics and Gynecology, Medical University of Innsbruck, Innsbruck, Austria
³Universitätsmedizin Göttingen, Göttingen, Germany
⁴Department of Obstetrics and Gynaecology, Molecular Oncology Group, Comprehensive Cancer Center-Gynaecologic Cancer Unit, Medical University of Vienna, Vienna, Austria
⁵Department of Pathology, Charité - Universitätsmedizin Berlin, Berlin, Germany
⁶Department of Gynaecology, European Competence Center for Ovarian Cancer, Charité - Universitätsmedizin Berlin, Berlin, Germany
⁷Centre Anticancereux Léon Bérard, GINECO group, University Claude Bernard Lyon, Lyon, France
⁸Centre Anticancereux Léon Bérard, University Claude Bernard Lyon, Lyon, France
⁹IRCCS Azienda Ospedaliero, Universitaria di Bologna, Bologna, Italy
¹⁰Division of Gynecological Oncology, Department of Gynecology and Obstetrics, Leuven Cancer Institute, Belgium and Luxembourg Gynaecological Oncology Group, Katholieke Universiteit Leuven, Leuven, Belgium
¹¹Fondazione Policlinico Universitario Gemelli IRCCS, Catholic University of Sacred Heart, Rome, Italy
¹²Department of Hematology, Oncology, and Cancer Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany
¹³German Cancer Consortium (Deutsches Konsortium für Translationale Krebsforschung, DKTK), Berlin, Germany
¹⁴Department of Obstetrics and Gynecology, Stanford University, Stanford, CA

William G Dunn^1*, Isabella Withnell^2*, Muxin Gu^3*, Pedro Quiros^3*, Sruthi Cheloor Kovilakam^3*, Ludovica Marando^3*, Margarete Fabre^4,5*, Irina Mohorianu^3*, Dragana Vuckovic^2* and George Vassiliou, FRCPath, MRCP, PhD, MBBS⁶

¹Wellcome-Mrc Cambridge Stem Cell Institute, Cambridge, United Kingdom
²Imperial College London, London, United Kingdom
³Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom
⁴Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom
⁵Department of Haematology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom
⁶Wellcome-MRC Cambridge Stem Cell Institute, University of Cambridge, Cambridge, United Kingdom

Hongyul An, MD^1*, Silvia Park^2,3*, Jiwoo Lim^4*, Byoung-Sik Cho^3,5*, Jong Hyuk Lee, MD^6*, Youngil Koh, MD^4,7,8,9 and Heeje Kim, MD, PhD^3,10

¹Genome Opinion, Seoul, South Korea
²Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, AL, South Korea
³Leukemia Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
⁴Genome Opinion, Seoul, Korea, Republic of (South)
⁵Department of Hematology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
⁶Department of Hematology, Incheon St.Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea
⁷Biomedical Research Institute, Seoul National University Hospital, Seoul, Korea, Republic of (South)
⁸Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea, Republic of (South)
⁹Cancer Research Institute, Seoul National University Hospital, Seoul, Korea, Republic of (South)
¹⁰Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)

Ksenia R. Safina, PhD^1*, Shawn David, MS, BS^2*, Kyle A. Romine, PhD^1*, Kristina D. Mujica^2*, Daniel Ssozi, BS^1*, Jonathan Good, BS^1*, Nurefsan Sariipek, MD^1*, Yoke Seng Lee^1*, Adrienne Parsons, PhD^1*, Sarah Bibeau, BS^1*, Adam S. Sperling, MD, PhD^3*, Christopher James Gibson, MD⁴, Gabriel K. Griffin, MD^5*, Alexander G. Bick, MD, PhD^6*, Antonia Kreso, MD, PhD^7,8*, Jennifer J. Trowbridge, PhD² and Peter van Galen, PhD¹

¹Division of Hematology, Brigham and Women's Hospital, Boston, MA
²The Jackson Laboratory, Bar Harbor, ME
³Dana Farber Cancer Institute, Boston, MA
⁴Dana-Farber Cancer Institute, Boston, MA
⁵Department of Pathology, Dana-Farber Cancer Institute, Boston, MA
⁶Department of Medicine, Vanderbilt University Medical Center, Nashville, TN
⁷Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA
⁸Harvard Medical School, Boston, MA

Ryunosuke Saiki^1*, Ryuya Edahiro^2*, Kyuto Sonehara^3,4*, Qingbo S Wang^3,4*, Ho Namkoong^5*, Takanori Hasegawa^6*, Hiromu Tanaka^7*, Shuhei Azekawa^7*, Shotaro Chubachi^7*, Shinichi Namba^3*, Kenichi Yamamoto^3,8,9*, Nobuyuki Kakiuchi, MD, PhD^10*, Yuichi Shiraishi^11*, Kenichi Chiba^11*, Hiroko Tanaka^6*, Hideki Makishima, MD, PhD¹⁰, Yasuhito Nannya, MD, PhD¹, Ryuji Koike^12*, Tomomi Takano^13*, Makoto Ishii^14*, Akinori Kimura^7*, Seiya Imoto^15*, Satoru Miyano, PhD^6*, Takanori Kanai^16*, Koichi Fukunaga^7*, Yukinori Okada^3,4,17,18* and Seishi Ogawa^19,20

¹Department of Pathology and Tumor Biology, Kyoto University, Kyoto, Japan
²Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, JPN
³Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan
⁴Department of Genome Informatics, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan
⁵Department of Infectious Diseases, Keio University School of Medicine, Tokyo, Japan
⁶M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan
⁷Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
⁸Laboratory of Children's health and Genetics, Division of Health Science, Osaka University Graduate School of Medicine, Suita, Japan
⁹Department of Pediatrics, Osaka University Graduate School of Medicine, Suita, Japan
¹⁰Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
¹¹Division of Cellular Signaling, National Cancer Center Research Institute, Tokyo, Japan
¹²Health Science Research and Development Center, Tokyo Medical and Dental University, Tokyo, Japan
¹³Laboratory of Veterinary Infectious Disease, Department of Veterinary Medicine, Kitasato University, Tokyo, Japan
¹⁴Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan
¹⁵Division of Health Medical Intelligence, Human Genome Center,, The Institute of Medical Science, the University of Tokyo, Tokyo, Japan
¹⁶Division of Gastroenterology and Hepatology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
¹⁷Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan
¹⁸Laboratory for Systems Genetics, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan
¹⁹Department of Pathology and Tumor Biology, Kyoto University Graduate School of Medicine, Sakyoku, KYO, Japan
²⁰Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan

Jean-Baptiste Micol, MD¹, Ahmadreza Arbab^2*, Damien Vasseur^3*, Arnaud Bayle^2*, Mihaela Aldea^2*, Romain Loyaux^2*, Veronique Verge^2*, Veronique Saada^2*, Alice Fievet^2*, Nathalie Auger^2*, Sophie Cotteret^2*, Florence Pasquier, MD, PhD^2*, Christophe Willekens, MD^4*, Camille Bigenwald^2*, Cristina Castilla-Llorente, MD^5*, Stephane De Botton, MD, PhD^6*, Eric Solary, MD^7*, Elsa Bernard^2*, Etienne Rouleau^3*, Antoine Italiano^2*, Christophe Marzac^2* and Aline Renneville^3*

¹Institut Gustave Roussy, Villejuif, France
²Gustave Roussy, VILLEJUIF, France
³Gustave Roussy, Villejuif, France
⁴Hematology Department, Institut Gustave Roussy, Villejuif, France
⁵Department of Hematology, Gustave Roussy Cancer Campus, Villejuif, France
⁶Department of Hematology, Institut Gustave Roussy, Villejuif, France
⁷GUSTAVE ROUSSY, Villejuif, Val DE Marne, FRA

Laura Poisa-Beiro, PhD^1*, Jonathan JM Landry, PhD^2*, Michael Kardorff^1*, Volker Eckstein^3*, Laura Villacorta^4*, Anne-Claude Gavin, PhD^5*, Vladimir Benes^6*, Simon Raffel, MD^1* and Anthony D Ho, MD⁷

¹Department of Medicine V, Universität Heidelberg, Heidelberg, Germany
²EMBL, Heidelberg, BW, DEU
³Heidelberg University Hospital, Heidelberg, Germany
⁴Genomic Core Facility, European Molecular Biology Laboratories, Heidelberg, Heidelberg, Germany
⁵Department for Cell Physiology and Metabolism, University of Geneva, Geneva, Switzerland
⁶Genomic Core Facility, European Molecular Biology Laboratory, Heidelberg, Germany
⁷Medicine, Universität Heidelberg, Heidelberg, Germany

Venkatasubramaniam Sundaramurthy, MS^1,2,3*, Yue Yuan, MD PhD^4,5*, Xiaoyan Zhang, MS^2,3*, Jia Song, MD MS^4,5*, Na Li, PhD^4,5* and Margaret Goodell, PhD^3,5,6,7

¹Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX
²Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston
³Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston
⁴Department of Medicine, Baylor College of Medicine, Houston
⁵Cardiovascular Research Institute, Baylor College of Medicine, Houston
⁶Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX
⁷Baylor College of Medicine, Houston, TX

Radhika Gangaraju, MD¹, Katherine Wilkinson, MS^2*, Nicole Armstrong, PhD^3*, Alexander G. Bick, MD, PhD^4*, Caitlyn Vlasschaert, MD, PhD^5*, Wasay Khan, MBBS, MS^6*, Diego Adrianzen Herrera, MD², Marguerite Irvin, PhD^7*, Nels Olson, PhD^8*, Mary Cushman, MD, MSc^2*, Smita Bhatia, MD, MPH³ and Neil A. Zakai, MD, MSc^2*

¹University Of Alabama, Birmingham, AL
²University of Vermont Larner College of Medicine, Burlington, VT
³University of Alabama at Birmingham, Birmingham, AL
⁴Department of Medicine, Vanderbilt University Medical Center, Nashville, TN
⁵Department of Medicine, Queen’s University, Kingston, ON, Canada
⁶Vanderbilt University Medical Center, Nashville, TN
⁷University of Alabama At Birmingham, Birmingham, AL
⁸University of Vermont Larner College of Medicine, Colchester, VT

Zhiqian Zheng, MS^1*, Akiho Tsuchiya, PhD^1*, Emmanuelle A. Passegue, PhD², Atsushi Iwama, MD, PhD¹ and Masayuki Yamashita, MD, PhD³

¹Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
²Columbia Stem Cell Initiative, Department of Genetics & Development, Columbia University Irving Medical Center, New York, NY
³The University of Tokyo, Tokyo, TKY, Japan

Uma M. Borate, MD¹, Kaitlyn M. Dvorak-Kornaus, PhD^2*, Qiuhong Zhao, MS^2*, Ann-Kathrin Eisfeld, MD*³ and Bethany L Mundy-Bosse, PhD⁴

¹Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH
²Division of Hematology, The Ohio State University, Columbus, OH
³Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University, Columbus, OH
⁴Comprehensive Cancer Center, The James Cancer Hospital and Solove Research Institute, Columbus, OH