Bailee Nicole Kain, PhD^1*, Brandon Tran, BS^2*, Pamela Luna, PhD^2*, Ruoqiong Cao, MS^2*, Duy Le, PhD^2*, Marcus Alexander Florez, PhD², Laure Maneix, PhD^2*, Jack Toups², Daniel Enrique Morales-Mantilla, PhD^2*, Scott Koh, BS^2*, Hyojeong Han, MD³, Yun Nancy Huang, PhD⁴, Andre Catic, MD, PhD², Chad Shaw, PhD^2* and Katherine Y. King, MD, PhD^5,6,7

¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH
²Baylor College of Medicine, Houston, TX
³Department of Hematology, Children's National, Washington D.C., DC
⁴Institute of Bioscience and Technology, Texas A&M University, Houston, TX
⁵Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX
⁶Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX
⁷Pediatric Infectious Diseases, Baylor College of Medicine, Houston, TX

Hanzhi Luo, PhD¹, Mariela Cortés-López, PhD^2,3,4*, Cyrus L. Tam^5,6*, Michael Xiao^7*, Isaac Wakiro, BSc^7*, Karen L. Chu^7*, Aspen Pierson^1*, Mandy Chan^1*, Kathryn Chang^7*, Xuejing Yang, PhD^7*, Grace Han^7*, Erin Ahn, PhD⁸, Quaid D. Morris, PhD^5*, Dan A. Landau, MD, PhD^2,9* and Michael G. Kharas, PhD¹⁰

¹Memorial Sloan Kettering Cancer center, New York, NY
²New York Genome Center, New York
³Meyer Cancer Center, Weill Cornell Medicine, New York, NY
⁴Institute of Computational Biomedicine, Weill Cornell Medicine, New York
⁵Computational and Systems Biology Program, Memorial Sloan Kettering Cancer Center, New York
⁶Tri-Institutional Training Program in Computational Biology and Medicine, Weill Cornell Medicine, New York
⁷Memorial Sloan Kettering Cancer Center, New York
⁸Bristol Myers Squibb, Princeton, NJ
⁹Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine, New York
¹⁰Molecular Pharmacology Program, Center for Cell Engineering, Center for Stem Cell Biology, Center for Experimental Therapeutics, Center for Hematologic Malignancies, Memorial Sloan Kettering Cancer Center, New York, NY

Michael McCONVILLE^1*, Toby Thomas, B.S.^2*, Catherine Valadez, B.S. M.S.^3*, Ryan Beckner, B.S.^3*, Yuh Min Chook, Ph.D.^4*, Stephen Chung, M.D.² and Glen Liszczak, Ph.D.^3*

¹Department of Biochemistry, University of Texas Southwestern Medical Center, Irving, TX
²Division of Hematology/Oncology, Department of Internal Medicine, Children's Research Institute, University of Texas Southwestern, Dallas, TX
³Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX
⁴Departments of Pharmacology and Biophysics, University of Texas Southwestern Medical Center, Dallas, TX

Saritha S. D'souza, PhD^1*, Akhilesh Kumar^1*, Yoon Jung Choi, Ph.D^1*, Samuel Dettle^1*, Isla Emmen^1*, Portia Smith, BS^1*, Divine M. Sedzro, Ph.D^1*, Ho Sun Jung, Ph.D^1*, Peng Liu, PhD^2* and Igor Slukvin, MD^1,3,4

¹Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI
²Department of Biostatistics and Biomedical Informatics, Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI
³Department of Cell and Regenerative Biology, University of Wisconsin School of Medicine and Public Health, Madison, WI
⁴Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI

Greta Zara, PhD^1*, Amy Leung, PhD^2*, Hiroyuki Kato^2*, Dustin Schones, PhD^3*, Young-Woong Kim, PhD^2*, Sonia Rodriguez-Rodriguez, PhD^2*, Huajia Zhang, PhD^4*, Zhaohui Gu, PhD³ and Nadia Carlesso, MD, PhD⁵

¹Stem Cell Biology & Regenerative Medicine, City of Hope, Duarte, CA
²City of Hope, Duarte
³City of Hope, Duarte, CA
⁴Indiana University School of Medicine, Indianapolis, IN
⁵Beckman Research Institute At City of Hope, Duarte, CA

Leah Gehrs^1*, Lana Vukadin^1*, Mostafa Mohamed^1*, Bohye Park^1*, Huashi Li^1*, Amr Elkholy^1*, Hyung-Gyoon Kim^1*, Xinyue Zhou, BPharm^2*, Sajesan Aryal², Steve Lim^1,3*, Rui Lu, PhD^3,4 and Erin Ahn, PhD^1,3

¹Department of Pathology, University of Alabama at Birmingham, Birmingham, AL
²Department of Medicine, Division of Hematology/Oncology, University of Alabama at Birmingham, Birmingham, AL
³O'Neal Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL
⁴Department of Medicine, Division of Hematology/Oncology, University of Alabama At Birmingham, Birmingham, AL

Sultan A Alsuhaibani, MS^1*, Jeanette Y Sullivan, BS^2*, Tiffany Trieu, BS^3*, Helen Huang^4*, Jianhong C Heidmann, BS^3*, Jared E Agagas, BS^5*, Kevin Arango, BS^5*, Dennis Jing, BS^6*, Gajalakshmi Ramanathan, PhD^5* and Angela G. Fleischman, MD, PhD³

¹Department of Biological Chemistry, University of California, Irvine, Irvine, CA
²Biological Chemistry, University of California, Irvine, IRVINE, CA
³Division of Hematology/Oncology, University of California, Irvine, Irvine, CA
⁴Division of Hematology/Oncology, University of California, Irvine, IRVINE, CA
⁵University of California, Irvine, Irvine, CA
⁶University of California, Irvine, Irvine

Sarah Waldvogel¹, Rachel E. Rau^2*, Virginia Camacho, PhD³, Ashlyn G. Laidman^1*, Anna Guzman^4*, Alejandra G Martell^1*, Kellie Machlus, PhD^5* and Margaret Goodell, PhD⁶

¹Baylor College of Medicine, Houston, TX
²Ben Towne Center for Childhood Cancer Research, Seattle Children’s Hospital, Seattle, WA
³Harvard Medical School, Boston, MA
⁴Baylor College of Medicine, Houston
⁵Boston Children's Hospital, Arlington, MA
⁶Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX

Charlotte Hellmich, PhD, BSc, MBBChir^1,2, Edyta E Wojtowicz, PhD^3*, Dominic Fowler-Shorten^4*, Rebecca S Maynard, MSc^4*, Katherine Hampton, MSc, BSc^1*, Iain Macaulay^3*, Kristian Bowles, MBBS, PhD^1,2 and Stuart Rushworth, PhD¹

¹Norwich Medical School, University of East Anglia, Norwich, United Kingdom
²Norfolk and Norwich University Hospital, Norwich, United Kingdom
³Earlham Institute, Norwich, United Kingdom
⁴Norwich Medical School, University of East Anglia, Norwich, ENG, United Kingdom

Qing Li^1*, Linjie Wu^1*, Fang Liu, MD^1,2*, Huimin Sun^1*, Yingying Huo^1*, Shihui Ma, MD^1*, Fang Dong^3*, Xiaofan Zhu^1,2*, Sha Hao^1,2* and Tao Cheng^1,2

¹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical Colleg, Tianjin, China
²Tianjin Institutes of Health Science, Tianjin, China
³State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences&Peking Union Medical College, Tianjin, China

Matthew Bratkowski, PhD^1*, Amirhossein Mafi, PhD^1*, Jiefei Geng, PhD^2*, Yuliya Kutskova, PhD^2*, Alysso Brito^2*, Manoj K Rathinaswamy, PhD^1*, Janani Sridar, MS^1*, Dan Eaton, PhD^1*, Qi Hao, PhD^1* and Marcia Paddock, MD, PhD^1*

¹Calico Life Sciences LLC, South San Francisco, CA
²AbbVie, Worcester, MA

James Ropa, BS, MSc, PhD¹, Sarah Gutch, BS^1*, Gracie Whitacre^1*, Lindsay Beasley, MS^1*, Wouter Van't Hof, PhD^2*, Mark H Kaplan, PhD^1* and Maegan L Capitano, PhD¹

¹Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN
²Cleveland Cord Blood Center, Cleveland, OH

Olivia Perrone, MD¹, Tiziana Coppola, MD¹, James Bartram, PhD^2*, Waseem Nasr, PhD³, Juying Xu^3* and Marie-Dominique Filippi, PhD³

¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH
²Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center and Research Foundation, Cincinnati, OH
³Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

Wade W Sugden, PhD¹, Zachary LeBlanc^1*, Mayuri Tanaka-Yano, PhD¹, Ran Jing^2*, Maria Gonzalez di Tillio^1*, Mohamad Najia, PhD^1*, Yang Tang^1*, Elizabeth Molnar^1*, Stephan George^1*, Brittney Love^1*, Caroline Kubaczka^1*, Nan Liu^1*, Nah-Young Shin, PhD^1*, Thorsten M. Schlaeger, PhD^2*, Edroaldo Lummertz da Rocha, PhD^3*, Alan B. Cantor, MD, PhD⁴, Stuart H Orkin, MD¹, Robert Grant Rowe¹, Wolfram Goessling, MD, PhD⁵, George Q. Daley, MD, PhD¹ and Trista E. North, PhD⁶

¹Department of Hematology/Oncology, Harvard Medical School/Boston Children's Hospital, Boston, MA
²Harvard Medical School/Boston Children's Hospital, Boston, MA
³Graduate Program of Pharmacology, Federal University of Santa Catarina, Florianopolis, Brazil
⁴Division of Pediatric Hematology/Oncology, Boston Children's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
⁵Brigham and Women's Hospital, Boston, MA
⁶Stem Cell Program, Boston Children's Hospital, Harvard Medical School, Boston, MA

Wenjie Cai, MS^1,2, Sisi Chen, PhD^2*, Xicheng Liu, PhD^3*, Xintong Chen, MS^1*, Sergio Barajas, BS^1,2, Shiyu Xiao, MS¹, Hongxia Chen, MD/PhD^1,2*, Rongwen Xi, PhD^3*, Zhonghua Gao, PhD^4*, Feng Yue, PhD¹ and Yan Liu, PhD¹

¹Northwestern University, Chicago, IL
²Indiana University, Indianapolis, IN
³National Institute of Biological Science, Beijing, China
⁴Pennsylvania State University, Hershey, PA

Hassan Bjeije^1*, Nancy Issa, MD^2*, Wentao Han², Yanan Li, PhD^3*, Wei Yang, PhD^4*, Jeffrey Magee, MD, PhD^5,6 and Grant A Challen, PhD²

¹Division of Oncology, Washington University School of Medicine, Saint Louis, MO
²Division of Oncology, Washington University School of Medicine, St. Louis, MO
³Department of Pediatrics, Division of Hematology and Oncology, Washington University School of Medicine, St. Louis, MO
⁴Department of Genetics, Washington University School of Medicine, St. Louis, MO
⁵Department of Pediatrics, Washington University School of Medicine, St. Louis, MO
⁶Washington University School of Medicine, Saint Louis, MO

Gerard Madlambayan, PhD^1*, Morgan Markel^1*, Tyler M Parsons, PhD², Sarah Hosch, PhD^1*, George Wilson, PhD^3*, Randal Joseph Westrick, PhD⁴ and Luis Villa-Diaz, PhD^1*

¹Biological Sciences, Oakland University, Rochester, MI
²Washington University School of Medicine In St. Louis, Saint Louis, MO
³Radiation Oncology, Corewell Hospital, Royal Oak, MI
⁴Oakland University, Rochester, MI

Chengfang Zhou^1*, Mei Kuang^2*, Jianming Wang^3*, Yu Luo^3* and Yu Hou, PhD⁴

¹institute of life sciences, Chongqing Medical University, Chongqing, China
²Department of Hematology, Army Medical University, Chongqing, China
³Institute of life sciences, Chongqing Medical University, Chongqing, China
⁴Institute of Life Sciences, Chongqing Medical University, CHONGQING, Chongqing, China

Chen Wang, MD, PhD^1*, Yi Zheng, PhD^1*, Cuiqing Fan, PhD^1*, Zhaowei Tu, PhD^1*, Xiongwei Cai, PhD^1*, Jianqiang Wu, MD, MS^1* and Gang Huang, PhD²

¹Division of Experimental Hematology and Cancer Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
²Department of Pathology and Laboratory Medicine, UT Health San Antonio, San Antonio, TX