Yunxiang Zhang^1*, Qiusheng Chen^1*, Xiangqin Weng, Master^1*, Yang Shen^1*, Wen Wu^1*, Jiong Hu¹, Jie Hao^2*, Ligen Liu, MD³ and Junmin Li^1*

¹Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
²Shanghai Jing'an District Beizhan Hospital, Shanghai, China
³Shanghai Tongren Hospital, Shanghai, China

Nigel H. Russell, MD¹, Abin Thomas^2*, Robert Hills^3*, Ian Thomas^4*, Amanda Gilkes^2*, Nuria Almuina^5*, Sarah Burns^6*, Lucy Marsh^7*, Georgia Andrew^8*, Nicholas McCarthy^9*, Jennifer Byrne^10*, Rob Sellar, FRCPath, MBBChir^11*, Richard J. Kelly, BSc, MD^12*, Paul Cahalin^13*, Ulrik Malthe Overgaard^14*, Priyanka Mehta, MD, FRCPath, MRCP^15*, Mike Dennis, MD, MRCP, FRCPath¹⁶, Steve Knapper^4* and Sylvie D Freeman¹⁷

¹Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom
²Cardiff University, Cardiff, GBR
³University of Oxford, Oxford, GBR
⁴Cardiff University, Cardiff, United Kingdom
⁵Centre For Trials Research, Cardiff University, Cardiff, GBR
⁶Centre For Trials Research,Cardiff University, Cardiff, GBR
⁷Cardiff University, Cardiff, United Kingdom
⁸AstraZeneca, Gaithersburg
⁹University of Birmingham, UK, Brimingham, GBR
¹⁰Nottingham University Hospitals NHS Trust, Nottingham, GBR
¹¹University College London, London, GBR
¹²Department of Haematology, St. James’s University Hospital, Leeds, United Kingdom
¹³Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool, GBR
¹⁴Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
¹⁵University Hospitals Bristol NHS Foundation Trust, Bristol, GBR
¹⁶The Christie, Manchester, GBR
¹⁷Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom

Barbara De Moerloose, MD^1*, Nira Arad-Cohen^2*, Daniel Cheuk^3*, Jose Maria Fernandez Navarro^4*, Henrik Hasle⁵, Kirsi Jahnukainen^6*, Gertjan J.L. Kaspers, MD, PhD⁷, Zhanna Kovalova^8*, Birgitte Lausen^9*, Ulrika Norén-Nyström, MD, PhD^10*, Josefine Palle^11*, Ramune Pasauliene^12*, Cornelis Jan Pronk, MD, PhD^13*, Kadri Saks^14*, Anne Maria Tierens, MD, PhD^15,16, Bernward Zeller, PhD^17* and Jonas Abrahamsson^18*

¹Department of Pediatric Hematology-Oncology, Ghent University Hospital, Ghent, Belgium
²Department of Pediatric Hemato-Oncology, Rambam Health Care Campus, Haifa, Israel;, Haifa, Israel
³Department of Pediatrics and Adolescent Medicine, Hong Kong Children's Hospital, University of Hong Kong, Hong Kong, China
⁴Department of Pediatric Hemato-Oncology, Hospital Universitario y Politécnico La Fe, Valencia, Spain
⁵Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark
⁶Children's Hospital, University of Helsinki and Helsinki University Central Hosp, Helsinki, FIN
⁷VU University Medical Center, Utrecht, Netherlands
⁸Department of Pediatric Oncology/Hematology, Children's Clinical University Hospital, Riga, Latvia
⁹Department of Pediatrics and Adolescent Medicine, Rigshospitalet, University of Copenhagen, Denmark, Copenhagen, Denmark
¹⁰Department of Clinical Sciences, Pediatrics, Umeå University Hospital, Umeå, Sweden
¹¹Department of Women´s and Children´s Health, Uppsala University, Uppsala, Sweden, Uppsala, Sweden
¹²Center for Pediatric Oncology and Hematology, Vilnius University Children’s Hospital, Vilnius, Lithuania
¹³Childhood Cancer Center, Skåne University Hospital, Lund, Sweden
¹⁴Department of Hematology Oncology, Tallinn Children´s Hospital, Tallinn, Estonia
¹⁵Laboratory Medicine Program, University Health Network, University of Toronto, Toronto, ON, Canada
¹⁶Laboratory Medicine Program, University Health Network, Toronto, ON, Canada
¹⁷Department of Pediatric Hematology-Oncology, Oslo University Hospital, Oslo, Norway
¹⁸Institution for Clinical Sciences, Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, Gothenburg, Sweden

Alexander Perl¹, Harry P. Erba, MD, PhD², Pau Montesinos, PhD, MD^3*, Radovan Vrhovac, MD, PhD^4*, Elzbieta Patkowska, MD^5*, Heeje Kim, MD, PhD⁶, Pavel Zak^7*, Po-Nan Wang, MD^8*, Jaime E Rohrbach, PhD^9*, Ken C N Chang, PhD^10*, Li Liu^11*, Yasser Mostafa Kamel^12*, Karima Imadalou^13*, Arnaud Lesegretain^14*, Jorge Cortes, MD¹⁵, Mikkael A. Sekeres, MD¹⁶, Hervé Dombret^17*, Sergio Amadori, MD¹⁸, Jianxiang Wang, MD¹⁹, Richard F Schlenk^20* and Mark J. Levis, MD, PhD²¹

¹Division of Hematology/Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA
²Duke Cancer Institute, Durham, NC
³Hospital Universitari i Politecnic la Fe, Valencia, Spain
⁴University Hospital Centre Zagreb, Zagreb, Croatia
⁵Hematology, IHIT Institute of Hematology and Blood Transfusion Warsaw, Warsaw, Poland
⁶Department of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of (South)
⁷University Hospital Hradec Kralove, Hradec Kralove, Czech Republic
⁸Chang Gung Medical Foundation, Linkou, Taiwan
⁹Daiichi Sankyo, Basking Ridge, NJ
¹⁰Daiichi Sankyo, Basking Ridge
¹¹Daiichi Sankyo, Inc, Basking Ridge
¹²Daiichi Sankyo, Inc., Basking Ridge
¹³Daiichi Sankyo, Inc, Basking Ridge, NJ
¹⁴Daiichi Sankyo Inc., Basking Ridge, NJ
¹⁵Georgia Cancer Center, Augusta University, Augusta, GA
¹⁶Sylvester Cancer Center, University of Miami, Miami, FL
¹⁷Saint Louis Hospital, University of Paris, Paris, FRA
¹⁸Tor Vergata Polyclinic Hospital Rome, Rome, ITA
¹⁹Institute of Hematology and Blood Diseases Hospital, Tianjin, China
²⁰Heidelberg University Hospital and German Cancer Research Center, Heidelberg, Germany
²¹Division of Hematologic Malignancies, Johns Hopkins University, Baltimore, MD

Alexandre Bazinet, MD^1*, Guillermo Garcia-Manero, MD², Nicholas J. Short, MD³, Yesid Alvarado Valero, MD³, Tareq Abuasab, MD^3*, Md Rabiul Islam, MD, MPH^4*, Kathryn Montalbano^1*, Ghayas C. Issa⁵, Abhishek Maiti, MD¹, Musa Yilmaz, MD^3*, Nitin Jain, MD³, Lucia Masarova, MD³, Steven M. Kornblau, MD³, Elias Jabbour⁶, Guillermo Montalban-Bravo, MD⁷, Sherry Pierce, BSN, BA^3*, Courtney D. DiNardo, MD, MSc³, Tapan M. Kadia, MD³, Naval Daver, MD³, Marina Y. Konopleva⁸, Hagop M. Kantarjian, MD⁹ and Farhad Ravandi, MD, MBBS¹⁰

¹Department of Leukemia, MD Anderson Cancer Center, Houston, TX
²University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴MD Anderson Cancer Center, Houston, TX
⁵Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX
⁶University of Texas M.D. Anderson Cancer Ctr., Houston, TX
⁷The University of Texas MD Anderson Cancer Center, Houston, TX
⁸Department of Oncology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY
⁹Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁰University of Texas- MD Anderson Cancer Center, Houston, TX

Xiaoping Li, PhD^1*, Xiaoyan Li^2*, Yanling Jin^3*, Zucong Chen^4*, Yonglin Shen^5*, Zhongtao Yuan, MD^1*, Lin Liu^1*, Yu Li, MD^1*, Le Luo, MD^1*, Shiqian Hou^6*, Chaoyang Zhou^7*, Chie Qiu^8*, Kui Zhang^9*, Chunfu Li, PhD^10,11, Yang Liang, MD, PhD¹² and Sanbin Wang Sr., MD, PhD^1*

¹Department of Hematology, 920th Hospital of Joint Logistics Support Force, Kunming, China
²The First People's Hospital of Baoshan, Baoshan, CHN
³The First People's Hospital of Qujing, Qujing, China
⁴Dehong People's Hospital, Dehong, China
⁵The People's Hospital of Honghe, Honghe, China
⁶The People's Hospital of Yuxi, Yuxi, China
⁷The People's Hospital of Chuxiong, Chuxiong, China
⁸Northeast Central Hospital of Yunnan Province, Zhaotong, China
⁹The Second People's Hospital of Qujing, Qujing, China
¹⁰Nanfang Hospital, Guangzhou, Guangdong, CHN
¹¹Nanfang-Chunfu Children‘s Institute of Hematology&Oncology, Dongguan, China
¹²Yale University School of Medicine Yale Cancer Center, Guangzhou, Guangdong, China