-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

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614.O1.6 614. Acute Lymphoblastic Leukemias: Therapies, Excluding Transplantation and Cellular Immunotherapies: Optimal Frontline Treatment for ALL

Symposia: Acute Lymphoblastic Leukemias: Therapies, Excluding Transplantation and Cellular Immunotherapies Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Lymphoid Leukemias, ALL, Diseases, Lymphoid Malignancies
Monday, December 11, 2023: 2:45 PM-4:15 PM
Grand Hall C (Manchester Grand Hyatt San Diego)
Moderators:
Jonathan Allen Webster, MD, Johns Hopkins University and Andishe Attarbaschi, Prof., MD, St. Anna Children's Hospital, Medical University Vienna
Disclosures:
Attarbaschi: JazzPharma: Honoraria.
2:45 PM

Tanja A. Gruber, MD, PhD1, Minxuan Huang, PhD1*, Sima Jeha, MD2, Rebecca J. Deyell, MD3*, Victor A. Lewis, MD4*, Bill H. Chang, MD, PhD5, Eric J. Lowe, MD6, Jamie Frediani, MD7*, Catherine Vezina, MD8*, Bruno Michon, MD9*, Nathan Gossai, MD, MS10, Erin H. Breese, MD, PhD11, Thai Hoa Tran, MD12, Norman J. Lacayo, MD13*, Christine Bolen, MD14, Sunil J. Desai, MBBS, FRCPC15, Jennifer L. Pauley, PharmD16*, Emily Ashcraft, MPH16*, Cheng Cheng17*, Kirk R. Schultz3, Krysta Schils, MD5*, Linda C. Stork, MD5, Van Thu Huynh18, Michael Richards, MD, PhD10, Yoav H. Messinger, MD10, Henrique Bittencourt19, Terzah M. Horton, MD, PhD20*, Uma Athale, MD, MBBS, MSc21, Duncan Stearns, MD22*, Deborah E. Schiff, MD23* and Paul S. Gaynon, MD24

1Stanford University School of Medicine, Palo Alto, CA
2Department of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN
3B.C. Children's Hospital, Vancouver, BC, Canada
4University of Calgary, Calgary, AB, Canada
5Doernbecher Children's Hospital, Oregon Health & Science University, Portland, OR
6Children's Hospital of the King's Daughters, Norfolk, VA
7Children's Hospital of Orange County, Orange, CA
8Montreal Children's Hospital, Montreal, QC, Canada
9Centre Hospitalier de l'Universite Laval, Quebec City, QC, Canada
10Children's Minnesota Hospital, Minneapolis, MN
11University of Cincinnati College of Medicine; Cincinnati Children's Medical Center, Cincinnati, OH
12CHU Sainte Justine, Montreal, QC, Canada
13Bass Center for Childhood Cancer and Blood Disorders, Department of Pediatrics, Stanford University, Stanford, CA
14Novant Health Hemby Children's Hospital, Charlotte, NC
15Stollery Childrens Hospital, Edmonton, AB, CAN
16St. Jude Children's Research Hospital, Memphis, TN
17Department of Biostatistics, St. Jude Children's Research Hospital, Memphis, TN
18Division of Oncology, Children's Hospital of Orange County, Orange, CA
19CHU Sainte-Justine, Montreal, Canada
20Baylor, Houston, TX
21McMaster University, Hamilton, ON, Canada
22Case Western Reserve University, Cleveland, OH
23Rady Children's Hospital, San Diego, CA
24Hematology/Oncology, Children's Hospital Los Angeles, Los Angeles, CA

3:00 PM

Vilmarie Rodriguez, MD1, Meenakshi Devidas, PhD, MBA2, Zhiguo (Bruce) Chen, MS3*, Andrew J Carroll, PhD4, Nyla A. Heerema, PhD5*, Michael J. Borowitz, MD, PhD6, Brent L. Wood, MD, PhD7, William L. Carroll, MD8, Naomi J Winick, MD9*, Elizabeth A. Raetz10*, Mignon L. Loh, MD11, Michael J. Burke, MD12*, Wanda L. Salzer, MD13, Stephen P. Hunger, MD14 and Karen R. Rabin, MD, PhD15

1Division of Pediatric Hematology/Oncology/Blood and Bone Marrow Transplant, Nationwide Children's Hospital/The Ohio State University, Columbus, OH
2St Jude Children's Research Hospital, Memphis, TN
3Biostatistics, University of Florida, Gainesville, FL
4Department of Genetics, University of Alabama at Birmingham, Birmingham, AL
5Ohio State University, Columbus, OH
6Johns Hopkins University School of Medicine, Baltimore, MD
7Department of Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA
8Perlmutter Cancer Center, Department of Pediatrics and Pathology, NYU Grossman School of Medicine, New York, NY
9Simmons Cancer Center and Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX
10New York University Langone Medical Center, New York, NY
11Ben Towne Center for Childhood Cancer Research, Seattle Children’s Hospital, Seattle, WA
12The Medical College of Wisconsin Inc, Milwaukee, WI
13U.S. Army Medical Research and Materiel Command, Fort Detrick, MD
14Childrens Hospital of Philadelphia, Philadelphia
15Department of Pediatrics, Baylor College of Medicine, Baylor College of Medicine TX Children's Cancer Center, Houston, TX

3:15 PM

Martin Schrappe, MD1, Franco Locatelli, MD, PhD2, Maria Grazia Valsecchi, PhD3*, Gunnar Cario, MD4*, Michaela Vossen-Gajcy5*, Jan Stary, MD, DSc6*, Andishe Attarbaschi, Prof., MD7*, Nicole Bodmer, MD8*, Draga Barbaric, MD9*, Sarah Elitzur, MD10, Daniela Silvestri11*, Alexandra Kolenova, MD, PhD12, Anja Möricke13*, Jean-Pierre Bourquin, MD, PhD14, Luciano Dalla-Pozza, MD15, Martin Stanulla, MD16*, Shai Izraeli, MD17, Carmelo Rizzari, MD18*, Fiona Poyer19*, Arend von Stackelberg, MD20*, Valentino Conter, MD21*, Martin Zimmermann, PhD22* and Andrea Biondi, MD3

1University Medical Center Schleswig-Holstein, Kiel, Germany
2Department of Pediatric Hematology and Oncology, IRCCS Ospedale Pediatrico Bambino Gesù, Catholic University of the Sacred Heart, Rome, Italy
3School of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy
4Department of Pediatrics, University Hospital Schleswig-Holstein, Kiel, Germany
5Department of Pediatrics I, Pediatric Hematology and Oncology, ALL-BFM Study Group, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany
6Department of Pediatric Hematology and Oncology, Second Faculty of Medicine, Charles University/University Hospital Motol, Prague, Czech Republic
7Department of Pediatric Hematology and Oncology, St. Anna Children's Hospital, Medical University Vienna, Vienna, Austria
8Department of Oncology, University Children's Hospital Zurich, Zurich, Switzerland
9Centre for Children's Cancer and Blood Disorders, Sydney Children's Hospital, Randwick NSW, AUS
10Schneider Children's Medical Center, Petah Tikva, Israel
11Tettamanti Center, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy
12Commenius Univ. Children's Hospital, Bratislava, SVK
13Pediatrics I, Ped. Hematology and Oncology, ALL-BFM Study Group, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany
14Department of Oncology and Children’s Research Center, University Children's Hospital Zurich, Zurich, Switzerland
15Cancer Center for Children, Sydney, Australia
16Department of Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany
17Department of Hematology-Oncology, Schneider Children's Medical Center of Israel, Petah Tikva, Israel
18Pediatrics, Fondazione IRCCS San Gerardo dei Tintori, Monza, Italy
19St. Anna Children's Hospital, Vienna, Austria
20Department of Pediatric Oncology and Hematology, Charité Universitaetsmedizin Berlin, Berlin, Germany
21Pediatric Clinic University of Milan Bicocca, Monza, ITA
22Department of Pediatric Hematology and Oncology, Medical School Hannover, Hannover, Germany

3:30 PM

Sabina Chiaretti, MD, PhD1, Irene Della Starza, PhD2,3*, Alessandra Santoro4*, Orietta Spinelli5*, Loredana Elia2*, Maria Stefania De Propris, MD, PhD2*, Matteo Piccini6*, Patrizia Chiusolo7*, Felicetto Ferrara, MD8*, Patrizia Zappasodi, MD9*, Erika Borlenghi, MD10*, Catello Califano11*, Monica Bocchia12*, Elisa Mauro, MD13*, Fabrizio Pane, MD14, Anna Candoni, Professor, MD15*, Albana Lico, MD16*, Ernesta Audisio, MD17*, Monia Lunghi, MD, PhD18*, Anna Maria Mianulli, MD19*, Mariangela Di Trani, Bachelor in Science2*, Valentina Arena, MS3*, Monica Messina, PhD3*, Alfonso Piciocchi, MS3*, Paola Fazi, MD3*, Alessandro Rambaldi, M.D.20, Robin Foà, MD2* and Renato Bassan21*

1Division of Hematology, Department of Translational and Precision Medicine, Division of Hematology, Rome, Italy
2Division of Hematology, Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy
3GIMEMA Foundation, Data Center and Health Outcomes Research Unit, Rome, Italy
4Division of Hematology and Bone Marrow Transplantation, Ospedali Riuniti Villa S, Palermo, ITA
5Hematology and Bone Marrow Transplant Unit, Azienda Socio-Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy
6SOD Ematologia, Università di Firenze, AOU Careggi, Firenze, Italy
7Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
8Divisione di Ematologia, Ospedale Cardarelli, Napoli, Italy
9Clinica Ematologica, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
10Hematology, ASST Spedali Civili, Brescia, Italy
11Unità Operativa Complessa di Onco-Ematologia del Plesso Ospedaliero “Andrea Tortora” di Pagani, Nocera Inferiore, ITA
12Hematology, AOU Senese, Siena, Siena, ITA
13Ospedale policlinico Vittorio Emanuele Ferrarotto, Catania, Italy
14Dipartimento Medicina Clinica e Chirurgia, UOC Ematologia e Trapianti di Midollo, Azienda Ospedaliera Universita Federico II, Napoli, Italy
15Clinica Di Ematologia E Unità Di Terapie Cellulari 'carlo Melzi'-Azienda, Udine, ITA
16Hematology Unit, San Bortolo Hospital, Vicenza, Italy, Vicenza, Italy
17SC Ematologia 2, AOU Città della Salute e della Scienza, Turin, Italy
18Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy
19Hematology Unit, Infermi Hospital, Rimini, AUSL Romagna, Rimini, Italy
20Hematology and Bone Marrow Transplant Unit, ASST Papa Giovanni XXIII, Bergamo, Italy
21Hematology Unit, Dell'Angelo Hospital, Mestre-Venezia, Italy

3:45 PM

Xiaoyuan Gong, MD1,2*, Qiuyun Fang, MD1,2*, Runxia Gu, MD1,2*, Shaowei Qiu, MD1,2*, Kaiqi Liu1,2*, Dong Lin1,2*, Chunlin Zhou1,2*, Guangji Zhang1,2*, Benfa Gong1,2*, Yuntao Liu1,2*, Shuning Wei1,2*, Yan Li, MD1,2*, Shouyun Li, MD1,2*, Bingcheng Liu, MD1,2*, Yimin Hu1,2*, Junfan Li1,2*, Ying Wang, MD1,2*, Hui Wei, MD1,2*, Yingchang Mi, MD1,2 and Jianxiang Wang, MD1,2

1National Clinical Research Center for Blood Diseases, State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Tianjin, China
2Tianjin Institutes of Health Science, Tianjin, China

4:00 PM

Nicola Goekbuget, MD1, Björn Steffen, MD2*, Kathrin Nachtkamp, MD3*, Boris Böll, M.D.4*, Veit L. Buecklein, MD5*, Christoph Faul, MD6, Jens Panse, MD7, Christoph Röllig, MD, MSc8*, Folker Schneller, MD9*, Bernd Spriewald, MD10*, Matthias Stelljes, MD11, Max S. Topp, MD12*, Andreas Viardot, MD PhD13, Vladan Vucinic, M.D.14*, Knut Wendelin, MD15*, Monika Brüggemann, MD16*, Monika Szczepanowski16*, Stefan Schwartz, MD17*, Thomas Burmeister, MD, PhD17*, Axel Benner18*, Nicholas Schreck18*, Lena Reiser1*, Hubert Serve, MD1 and Walter Fiedler, MD19

1Department of Medicine II, Hematology/Oncology, Goethe University Hospital, Frankfurt, Germany
2Department of Internal Medicine II, Hematology and Oncology, Goethe University Hospital Frankfurt, Frankfurt, Germany
3Dept. of Hematology, Oncology and Clinical Immunology, Düsseldorf University Hospital, Düsseldorf, Germany
4Department of Internal Medicine I, University Hospital, Cologne, Germany
5Department of Medicine III, University Hospital, LMU Munich, Munich, Germany
6Department of Internal Medicine II, Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tuebingen, Germany
7Center for Integrated Oncology - Aachen Bonn Cologne Duesseldorf (CIO-ABCD), Aachen, Germany
8Department of Internal Medicine I, University Hospital Dresden, Dresden, Germany
9Klinikum Rechts der Isar der TU München, Munich, Germany
10Department of Medicine 5, University Hospital of Erlangen, Erlangen, Germany
11University of Muenster, Muenster, Germany
12Universitätsklinikum Würzburg, Würzburg, Germany
13Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
14Department of Hematology, Cellular Therapy, Hemostaseology and Infectious Diseases, University of Leipzig, Leipzig, Germany
15Med Clinic 5, Klinikum Nürnberg, Nuernberg, Germany
16Clinic for Internal Medicine II - Haematology, Oncology, University Clinic Schleswig-Holstein, Kiel, Germany
17Corporate member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Department of Hematology, Oncology and Tumor Immunology (Campus Benjamin Franklin) Charité - Universitätsmedizin Berlin, Berlin, Germany
18Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany
19University Hospital Hamburg-Eppendorf, Hamburg, DEU

*signifies non-member of ASH