Rabea Mecklenbrauck^1*, Nora Borchert^1*, Piroska Klement^1*, Carolin Funke^1*, Maximilian Brandes^1*, Louisa-Kristin Dallmann^1*, Walter Fiedler^2*, Jürgen Krauter^3*, Arne Trummer^4*, Bernd Hertenstein, MD^5*, Verena I. Gaidzik⁶, Konstanze Döhner⁶, Hartmut Döhner, MD⁶, Arnold Ganser¹, Felicitas Thol¹ and Michael Heuser, MD¹

¹Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
²Department of Medicine II, University Hospital Hamburg-Eppendorf, Hamburg, Germany
³Department of Hematology and Oncology, Städtisches Klinikum Braunschweig, Braunschweig, Germany
⁴Department of Hematology, Oncology and Palliative Care, Heidekreis-Klinikum, Walsrode, Germany
⁵Department of Internal Medicine I, Klinikum Bremen Mitte, Bremen, Germany
⁶Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany

Curtis A Lachowiez, MD¹, Georgios Asimomitis^2,3*, Elsa Bernard, PhD^2*, Ivory Tang^4*, Yanis Tazi, MSc, BSc^5*, Amanda Gilkes^6*, Ian Thomas^7*, Lars Bullinger⁸, Konstanze Döhner⁹, Hartmut Dohner, MD¹⁰, Brian Huntly, PhD^11,12*, Nigel H. Russell, MD¹³, Sanam Loghavi, MD¹⁴ and Elli Papaemmanuil¹⁵

¹Knight Cancer Institute, Oregon Health & Science University, Portland, OR
²Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY
³Biomedical Systems Laboratory, Department of Mechanical Engineering, National Technical University of Athens, Athens, Greece
⁴Memorial Sloan Kettering Cancer Center, New York, NY
⁵Memorial Sloan Kettering Cancer Center, New York
⁶Cardiff University, Cardiff, GBR
⁷Cardiff University, Cardiff, United Kingdom
⁸Charité Universitätsmedizin Berlin, Berlin, Germany
⁹Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
¹⁰Department of Internal Medicine III, Ulm University Medical Center, Ulm, Germany
¹¹Wellcome - MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom
¹²Cambridge Institute For Medical Research, University of Cambridge, Cambridge, GBR
¹³Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom
¹⁴Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁵Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY

Enrico Attardi, MD^1*, Arianna Savi, MD^2*, Beatrice Borsellino, MD^1*, Marta Cipriani, MS^3,4*, Alfonso Piciocchi, MS^5*, Flavia Mallegni, MD^6*, Giorgia Silvestrini, MSc^1*, Hussein Awada^7*, Arda Durmaz, PhD^7*, Valeria Visconte, PhD⁷, Matteo Giovanni Della Porta, MD^8*, Adriano Venditti, MD⁶, Jaroslaw P. Maciejewski, M.D., Ph.D., FACP⁷, Carmelo Gurnari, MD^6,7 and Maria Teresa Voso, MD⁶

¹Department of Biomedicine and Prevention, PhD in Immunology, Molecular Medicine and Applied Biotechnology, University of Rome Tor Vergata, Rome, Italy
²University of Turin, Department of Clinical and Biological Sciences, Turin, Italy
³University of Rome La Sapienza, Department of Statistical Sciences, Rome, Italy
⁴Data Center and Health Outcomes Research Unit, GIMEMA Foundation, Rome, Italy
⁵GIMEMA Foundation, Data Center and Health Outcomes Research Unit, Rome, Italy
⁶Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
⁷Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
⁸IRCCS Humanitas Clinical & Research Center and Department of Biomedical Sciences, Humanitas University, Rozzano, Italy

Wajma Shahbaz^1*, Vindi Jurinovic, MSc^2,3*, Aarif M. N. Batcha^3*, Christian Rausch^2*, Maja Rothenberg-Thurley, PhD^2*, Annika Maria Dufour, PhD, MSC^2*, Bianka Ksienzyk^2,4*, Stephanie Schneider, PhD^2*, Michaela Neusser, PhD^2,5*, Maria Cristina Sauerland, MD^6*, Dennis Görlich, PhD⁶, Wolfgang E. Berdel, MD⁷, Bernhard J. Woermann, MD⁸, Utz Krug, MD^9*, Jan Braess, MD^10*, Wolfgang Hiddemann, MD^2*, Ulrich Mansmann^3*, Sebastian Vosberg^11,12*, Philipp A. Greif, MD^12,13, Karsten Spiekermann, MD^2,14*, Klaus H Metzeler, MD¹⁵ and Tobias Herold^12,16*

¹Department of Hematology and Onocology, University Hospital LMU Munich, Department of Medicine III, Munich, Germany
²Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany
³Institute of Medical Data Processing, Biometrics and Epidemiology (IBE), Faculty of Medicine, LMU Munich, Munich, Germany
⁴Institute of Human Genetics, University Hospital LMU, Munich, Germany
⁵Institute of Human Genetics, University Hospital, LMU Munich, Munich, Germany
⁶Institute of Biostatistics and Clinical Research, University of Münster, Muenster, Germany
⁷Department of Medicine A, Hematology and Oncology, University Hospital Muenster, Muenster, Germany
⁸German Society of Hematology and Oncology, Berlin, Germany
⁹Department of Medicine III, Hospital Leverkusen, Leverkusen, DEU
¹⁰Department of Oncology and Hematology, Hospital Barmherzige Brueder, Regensburg, DEU
¹¹Division of Oncology, Department of Internal Medicine, Medical University of Graz, Graz, Austria
¹²Department of Medicine III, Hematology and Oncology, University Hospital, LMU Munich, Munich, Germany
¹³German Consortium for Translational Cancer Research (DKTK), Partner Site Munich, Munich, Germany
¹⁴German Cancer Consortium (DKTK) Partner Site Munich, Munich, Germany
¹⁵Department for Hematology, Cell Therapy, Hemostaseology and Infectious Diseases, University of Leipzig Medical Center, Leipzig, Germany
¹⁶German Cancer Consortium (DKTK), Partner Site Munich, Munich, Germany

Pinkal Desai, MD, MPH¹, Yasmin Abaza, MD², Hetty E. Carraway, MD, MBA³, Jason Chua^4*, Michael Samuel, MD^5*, Cynthia Crispino^6*, Bridget Foley^7*, Sindhusha Veeraballi, MD^8*, Peter Doukas, MD^2*, Oluwatobi Odetola, MD⁹, Justin D. Kaner, MD⁵, Michal Bar-Natan, MD⁵, Ellen K. Ritchie, MD⁵ and Gail J. Roboz, MD⁵

¹Division of Hematology and Medical Oncology, EIPM Molecular Aging Institute, Weill Cornell Medicine, New York, NY
²Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL
³Department of Hematology and Medical Oncology, Taussig Cancer institute, Leukemia Program, Cleveland Clinic, Cleveland, OH
⁴Population Health Sciences, Weill Cornell Medicine, New York
⁵Division of Hematology and Medical Oncology, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY
⁶Weill Cornell Medicine, New York, NY
⁷John F Kennedy Catholic Preparatory School, New York
⁸Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic Foundation, Parsippany, NJ
⁹Division of Hematology/Oncology, Northwestern University Feinberg School of Medicine, Maywood, IL

Vikram Dhillon, DO, MBA^1,2, Jeff Aguilar, MD, MBA³, Sushmitha Nanja Reddy, MD, MBBS⁴, Lakshmi Bhavani Potluri, MD⁵, Gregory Dyson, PhD^6*, Jaroslaw P. Maciejewski, M.D., Ph.D., FACP⁷ and Suresh Kumar Balasubramanian, MD^6,7

¹Department of Hematology/Oncology, Neal Cancer Center/Houston Methodist Hospital, Detroit, MI
²Department of Oncology, Karmanos Cancer Center/Wayne State University, Detroit, MI
³Department of Oncology, Karmanos Cancer Institute/Wayne State University, Windsor, ON, Canada
⁴Karmanos Cancer Center/Wayne State University, Detroit
⁵Wayne State University/Sinai-Grace Hospital, Farmington Hills, MI
⁶Karmanos Cancer Institute/Department of Oncology, Wayne State University, Detroit, MI
⁷Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH