Junya Sango, PhD^1*, Saul Carcamo, PhD^1*, Nataly Cruz-Rodriguez, PhD¹, Maria Sirenko, PhD², Abhishek Maiti, MD³, Malgorzata Olszewska^1*, Tiansu Wang, PhD^1*, Gulay Bengu Ulukaya, PhD^1*, Lewis Tomalin^1*, Emmanuel Olivier, PhD^1*, Manon Jaud^1*, Ronan Chaligne, PhD^4*, Hager Mansour^1*, Deniz Demircioglu^1*, Dan A. Landau, MD, PhD^5*, Elli Papaemmanuil, PhD², Courtney D. DiNardo, MD, MSc⁶, Dan Hasson, PhD^1*, Marina Y. Konopleva⁷ and Eirini Papapetrou, MD, Phd, MD, PhD¹

¹Icahn School of Medicine at Mount Sinai, New York, NY
²Computational Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY
³Department of Leukemia, MD Anderson Cancer Center, Houston, TX
⁴Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY
⁵Division of Hematology and Medical Oncology, Department of Medicine and Meyer Cancer Center, Weill Cornell Medicine, New York
⁶Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷Department of Oncology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY

David Cruz Hernandez, PhD^1*, Nicolas Papadopoulos^2,3,4*, Elise Sepulchre^2,3*, Marlen Metzner^5*, Batchimeg Usukhbayar^5*, Mirian Angulo Salazar^5*, Leila Varghese^2,3,4*, Gabriel Levy^2,3,4*, Irene Roberts, MD⁶, Stefan N Constantinescu^2,4,7,8 and Paresh Vyas, FMedSci, DPhil, FRCPath^9*

¹MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, ENG, United Kingdom
²Université catholique de Louvain and de Duve Institute, Brussels, Belgium
³Ludwig Institute for Cancer Research, Brussels, Belgium
⁴WEL Research Institute, WELBIO Department, Wavre, Belgium
⁵MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom
⁶Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
⁷Nuffield Department of Medicine, University of Oxford, Ludwig Institute for Cancer Research, Oxford, United Kingdom
⁸Ludwig Institute For Cancer Research, Brussels, Belgium
⁹Weatherall Institute of Molecular Medicine, Oxford, United Kingdom

Amanda Tajik, BSc^1,2*, Emily Tsao, BSc^2,3, Brendon Seale, PhD^4*, Soheil Jahangiri, PhD^3*, Belma Abidin, PhD^5*, Lina Liu, PhD^3*, Zaldy Balde, MSc^3*, He Tian (Tony) Chen, BSc^3,5, Nicholas Wong, PhD^3*, Ava Keyvani Chahi, PhD^3*, Pratik Joshi, BSc^2,3*, Steven Moreira^3*, Curtis W. McCloskey, PhD^3*, Shahbaz Khan, PhD^3*, Helena Boutzen, PhD, PharmD^3*, Cassandra Wong, MSc^4*, Suraj Bansal^3*, Andy G.X. Zeng⁶, Stefan Aigner, PhD^7*, Yu Lu, PhD^8*, John E. Dick, PhD^3,9, Thomas Kislinger, PhD^2,3*, Rama Khokha, PhD^2,3*, Mark D. Minden^2,3*, Gene W. Yeo, PhD^7*, Anne-Claude Gingras, PhD^4,9* and Kristin J. Hope^2,3

¹Princess Margaret Cancer Centre, University Health Network, Mississauga, ON, Canada
²Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada
³Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
⁴Lunenfeld-Tanenbaum Research Institute, Toronto, ON, Canada
⁵Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada
⁶University Health Network, Princess Margaret Cancer Centre, Toronto, ON, Canada
⁷Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA
⁸Department of Medicine, McMaster University, Hamilton, ON, Canada
⁹Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada

Daiki Karigane, MD, PhD^1*, Amy C Fan, PhD^1*, Kensuke Kayamori, MD, PhD^1*, Yusuke Nakauchi, MD, PhD^1*, Thomas Koehnke, MD¹, Athreya S Rangavajhula^1*, Asiri Ediriwickrema, MD¹ and Ravi Majeti, MD²

¹Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA
²Stanford University School of Medicine, Stanford, CA

Clément Larrue, PhD^1*, Sarah Mouche^2*, Paolo Angelino^2*, Petros Tsantoulis^2*, Jean-Emmanuel Sarry, PhD^3* and Jerome Tamburini^2*

¹INSERM, TOULOUSE CEDEX 1, France
²Geneva University, Geneva, Switzerland
³Inserm, Toulouse, FRA

Sarah Skuli, MD, PhD¹, A'Ishah Bakayoko, BA^1*, Gerald Wertheim, MD, PhD^1,2*, Owen Riley^1*, Marisa Kruidenier, BA^1*, Bryan Manning, BS^1*, Akmal Salimov, BA^1*, Gisela Brake-Silla, MS^1*, Derek Dopkin, BA^1*, Jimmy Xu, PhD^3*, Eva Nee^3*, Lorelai Mesaros^3*, Ryan Hausler, MS^1*, Manuela Lavorato, PhD^4*, Eiko Ogiso, PhD^4*, Marni Falk, MD^4*, Kara Maxwell, MD, PhD^1*, Nicolas Skuli, PhD^1*, Clementina Mesaros, PhD^3* and Martin Carroll, MD¹

¹Division of Hematology/Oncology, Department of Medicine, The Perelman School of Medicine at The University of Pennsylvania, Philadelphia, PA
²Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA
³Department of Pharmacology, The University of Pennsylvania, Philadelphia, PA
⁴Mitochondrial Medicine Frontier Program, Division of Human Genetics, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA