Symposia: Sickle cell Disease, Sickle Cell Trait and Other Hemoglobinopathies, Excluding Thalassemias: Clinical and Epidemiological
Oral and Poster Abstracts
Oral
Research, clinical trials, Sickle Cell Disease, Biological therapies, Clinical Research, Hemoglobinopathies, Diseases, real-world evidence, Therapies
Room 31
(San Diego Convention Center)
Moderators:
Nicola Conran, PhD, University of Campinas - UNICAMP
and
Luke R. Smart, MD, ARRAY(0x10554624)
Disclosures:
Conran: Novartis Pharma AG: Research Funding.
Hydroxyurea has been available in established healthcare systems, and its effects in improving anemia, reducing frequency and severity of acute painful crises or acute chest syndromes, and stimulating fetal hemoglobin are well known. However, information on its long term use in less resourced countries, its effect on fertility, and how it is used with newer therapies being available, are less robust. This session aims to answer some of these important questions, which should help providers frame discussions about the growing list sickle cell medication treatment.
4:30 PM
Kristine Karkoska, MD, MS1 and Patrick T. McGann, MD, PhD2,3
1University of Cincinnati College of Medicine, Cincinnati, OH
2Lifespan Comprehensive Sickle Cell Center, Providence, RI
3The Warren Alpert Medical School of Brown University, Providence, RI
4:45 PM
Justin J Yoo, MD1, Jordan Zgodny, BA2*, Britney Hernandez, BS2*, Jawa Darazim, BS2*, Ashwin P Patel, MD, PhD, MPH2, Fuad El Rassi, MD3,4, G. Karen Yu, PhD5*, Alka A Potdar, PhD5* and Vivien A. Sheehan, MD, PhD2
1Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Avondale Estates, GA
2Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University School of Medicine, Atlanta, GA
3Department of Hematology and Medical Oncology, Emory University School of Medicine, Atlanta, GA
4Georgia Comprehensive Sickle Cell Center at Grady Health System, Atlanta, GA
5Pfizer Inc, South San Francisco, CA
5:00 PM
Clare Zarka1*, Amy Luo2*, Sacha Belinda Mapombo Choupa3, A. Kinga Malinowski, MD, FRCPC, MSc4, Kevin H.M. Kuo, MD, FRCPC, MSc5, Nadine Shehata, MD, FRCPC, MSc6, Sophie Lanzkron, MD7 and Lydia H Pecker, MD7,8
1Johns Hopkins University School of Medicine, Baltimore, MD
2Johns Hopkins Bloomberg School of Public Health, Baltimore
3Meharry Medical College, Nashville, TN
4Department of Obstetrics and Gynaecology, Division of Maternal-Fetal Medicine, Lunenfeld-Tanenbaum Research Institute, Sinai Health, University of Toronto, Toronto, ON, Canada
5Department of Hematology, University of Toronto, Toronto, ON, Canada
6Mount Sinai Hospital, Toronto, ON, Canada
7Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, MD
8Department of Gynecology and Obstetrics, Johns Hopkins University School of Medicine, Baltimore, MD
5:15 PM
Ryan Sun, MD1*, Brian Layden, MD1*, Joseph Zapatar, MD1*, Bill Galanter, MD1*, James Lash, MD2*, Jin Han, PharmD3*, Victor R. Gordeuk, MD4 and Santosh L. Saraf, MD5
1University of Illinois at Chicago, Chicago, IL
2University of Illinois College of Medicine At Chicago, Chicago, IL
3College of Pharmacy, University of Illinois Chicago, Chicago, IL
4Sickle Cell Center, University of Illinois at Chicago, Chicago, IL
5Division of Hematology/Oncology, University of Illinois Chicago, Chicago, IL
5:30 PM
Jackie Queen, MD, MPH1*, Emily Limerick, MD1, Neal Jeffries, PhD2*, Ritika Menon1*, Matthew M. Hsieh, MD3, Robert Shamburek1* and Courtney D. Fitzhugh, MD4
1National Institutes of Health, Bethesda, MD
2Office of Biostatistics Research, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD
3NIH-NHLBI-MCHB, Bethesda, MD
4Cellular and Molecular Therapeutics Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
5:45 PM
Martha O Kenney, MD1*, Samuel Wilson, MD2*, Morgan Rosser, MS3*, Sophie Lanzkron, MD4, Julie Kanter, MD5, Amma T. Owusu-Ansah, MD6, Alice J. Cohen, MD7, Deepa Manwani, MD8 and Jane A. Little, MD9
1Department of Anesthesiology, Duke University, Durham, NC
2Division of Hematology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC
3Department of Anesthesiology, Duke University, Durham
4Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, MD
5Division of Hematology and Oncology, University of Alabama, Birmingham, AL
6University Hospitals, Cleveland, OH
7Newark Beth Israel Med. Ctr., Newark, NJ
8Department of Pediatric Hematology-Oncology, Albert Einstein College of Medicine, Bronx, NY
9Division of Hematology and UNC Blood Research Center, University of North Carolina, Chapel Hill, NC
*signifies non-member of ASH
denotes an abstract that is clinically relevant.
denotes that this is a recommended PHD Trainee Session.
denotes that this is a ticketed session.