Grazia Fazio^1*, Michela Bardini^1*, Andrea Grioni^1,2*, Paola De Lorenzo^3*, Manuel Quadri^1*, Lucia Pedace^4*, Lilia Corral^1*, Sonia Palamini^1*, Barbara Buldini^5*, Rosanna Parasole^6*, Elena Barisone^7*, Marco Zecca^8*, Claudio Favre^9*, Franco Locatelli, MD^4*, Valentino Conter, MD^10*, Carmelo Rizzari^10*, Maria Grazia Valsecchi, PhD^3,11*, Andrea Biondi, MD¹⁰ and Giovanni Cazzaniga, PhD^1,12

¹Tettamanti Research Center, Dept. Pediatrics, University of Milano-Bicocca, Fondazione MBBM/San Gerardo Hospital, Monza, Italy
²CEITEC, Brno, Czech Republic
³Centro Operativo di Ricerca Statistica, Fondazione Tettamanti, School of Medicine and Surgery, University of Milan-Bicocca, Monza, Italy
⁴Pediatric Hemato-Oncology, IRCCS, Bambino Gesù Children’s Hospital, Sapienza, Univ of Rome, Rome, Italy
⁵Woman and Child Health Department, OncoHematology Lab, University of Padua, Padua, It, Italy
⁶Dept Pediatric Hemato-Oncology, Azienda Ospedaliera di Rilievo Nazionale Santobono Pausilipon, Napoli, Italy, NAPOLI, Italy
⁷Divison of Pediatric Hematology and Oncology, Stem Cell Transplantation and Cellular Therapy, Regina Margherita Children's Hospital, Torino, Italy
⁸Pediatric Hematology/Oncology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
⁹Dip. di Oncoematologia, Tumori pediatrici e Trapianto di cellule staminali, Azienda Ospedaliero-Universitaria Meyer, Florence, Italy
¹⁰Dept. Pediatrics, University of Milano-Bicocca, Fondazione MBBM/San Gerardo Hospital, Monza, Italy
¹¹Bicocca Bioinformatics, Biostatistics and Bioimaging Centre, Department of Medicine and Surgery, University of Milano - Bicocca, Monza, Italy
¹²Genetics, Univ. Milan Bicocca, Monza, Italy

Linda Kachuri, PhD, MPH^1*, Soyoung Jeon, BSc^2*, Andrew T. DeWan, PhD^3*, Catherine Metayer, MD, PhD^4*, John S. Witte, Ph.D.^1*, Xiaomei Ma, PhD^5*, Charleston W. K. Chiang, PhD^2*, Joseph L. Wiemels, PhD^2* and Adam J de Smith, PhD²

¹Department of Epidemiology & Biostatistics, University of California San Francisco, San Francisco, CA
²Center for Genetic Epidemiology, Department of Preventive Medicine, University of Southern California, Los Angeles, CA
³Department of Chronic Diseases, Yale School of Public Health, Yale University, New Haven, CT
⁴School of Public Health, University of California Berkeley, Berkeley, CA
⁵School of Public Health, Yale University, New Haven, CT

Dabing Chen^1*, Tingting Xiao^1*, Dandan Lin^1*, Haojie Zhu^1*, Jingjing Xu^1*, Xiaofeng Luo^1*, Jinhua Ren^1*, Zhihong Zheng^1*, Zhizhe Chen^1*, Jianda Hu, MD, PhD¹ and Ting Yang, MD, PhD²

¹Department of Hematology, Fujian Institute of Hematology, Fujian Provincial Key Laboratory of Hematology, Fujian Medical University Union Hospital, Fuzhou, China
²Department of Hematology, Fujian Medical University Union Hospital，Fujian Institute of Hematology, Fujian Provincial Key Laboratory on Hematology, Fuzhou, China

Lorenz Bastian^1*, Sonja Hänzelmann^1*, Martin Neumann^1*, Alina Hartmann^1*, Thomas Burmeister^2*, Stefan Schwartz^3*, Walter Fiedler, MD⁴, Mustafa Kondakci, MD^5*, Andreas Viardot, Professor Dr⁶, Folker Schneller^7*, Christoph Faul, MD⁸, Max S. Topp, MD⁹, Sören Franzenburg^10*, Andre Franke^10*, Heiko Trautmann, PhD^1*, Nicola Goekbuget, MD¹¹, Monika Brüggemann, MD^1* and Claudia D Baldus, MD^1*

¹Medical Department II, Hematology and Oncology, University Hospital Schleswig-Holstein, Kiel, Germany
²Department of Hematology / Oncology, Charité - Universitätsmedizin Berlin, Berlin, Germany
³Department of Hematology and Oncology, Charité - Campus Benjamin Franklin, Berlin, Germany
⁴Department of Oncology, Hematology and Bone Marrow Transplantation with Section Pneumology, University Cancer Center Hamburg, University Hospital Eppendorf, Hamburg, Germany
⁵Dept. of Hematology, Oncology and Clinical Immunology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany
⁶Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
⁷Medical Department III, Klinikum rechts der Isar, Technical University Munich, Munich, Germany
⁸University Hospital Tübingen, Tübingen, Germany
⁹Comprehensive Cancer Center Mainfranken and Department of Internal Medicine II, Division of Hematology and Medical Oncology, University Hospital Würzburg, Würzburg, Germany
¹⁰Institute of Clinical Molecular Biology, University Hospital Schleswig-Holstein, Kiel, Germany
¹¹University Hospital, Department of Medicine II, Hematology/Oncology, Head of Study Center Depart of Medicine II, Hematology/Oncology Goethe University Hospital, Frankfurt, Germany

Yang Zhang, MD¹, Fang Wang, MD¹, Xue Chen, MD^2*, Hong Liu, MD^1*, Xiaoliang Wang, MD^1*, Jiaqi Chen, MD^1*, Panxiang Cao, MS^1*, Xiaoli Ma, MD^1* and Hongxing Liu, MD^1,3,4

¹Division of Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Langfang, China
²Division of Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Beijing, China
³Beijing Lu Daopei Institute of Hematology, Beijing, China
⁴Division of Laboratory Medicine, Beijing Lu Daopei Hospital, Beijing, China

Laura N Eadie, BSc, PhD^1,2*, Jacqueline Rehn, MSc(BioTech)^1,2*, Susan L Heatley, PhD, MEd^1,2*, Barbara J McClure, BSc, PhD^1,2*, Caitlin Schutz Schutz, BSc (Hons)^2*, James Breen, BSc, PhD^1,3,4*, Timothy P. Hughes, MD, MBBS, FRACP, FRCPA^1,2,5,6, David T Yeung, BSc, PhD, FRACP, FRCPA, MBBS^1,2,5,6, Rosemary Sutton, BSc MSc PhD^5,7* and Deborah L White, PhD, FFSc(RCPA)^1,2,5,8

¹Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, SA, Australia
²Cancer Program, Precision Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia
³Computational and Systems Biology Program, Precision Medicine Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, SA, Australia
⁴Robinson Research Institute, The University of Adelaide, Adelaide, SA, Australia
⁵Australasian Leukaemia and Lymphoma Group (ALLG), Melbourne, Australia
⁶Department of Haematology, Royal Adelaide Hospital and SA Pathology, Adelaide, SA, Australia
⁷Children's Cancer Institute Australia, University of NSW, Randwick, NSW, Australia
⁸Australian Genomics Health Alliance (AGHA), Parkville, VIC, Australia

Lucy E Cain, BSc, MBBS, MPH¹, Oksana Mirochnik^2*, Michael M Stevens, MBBS FRACP^3*, Stewart J Kellie, MBBS FRACP MD MIntPH(Hons)^3,4*, Bhavna Padhye, MBBS FRACP MClinTRes PhD^3*, Steven J Keogh, MBBS(Hons) FRACP^3*, Dinisha Govender, MBChB FRACP^3*, Jessica Ryan, BMed(Hons) FRACP^3*, Luciano Dalla-Pozza, MBBS FRACP³ and Caroline M Bateman, PhD, MBBS, FRACP, FRCPath, MRCP^3,5

¹Cancer Centre for Children, The Children's Hospital at Westmead, Potts Point, NSW, Australia
²Institute of Clinical Pathology and Medical Research (ICPMR) NSW Health Pathology, Westmead, NSW, Australia
³Cancer Centre for Children, The Children's Hospital at Westmead, Westmead, NSW, Australia
⁴Discipline of Child and Adolescent Health, University of Sydney, Sydney, NSW, Australia
⁵Westmead Institute of Medical Research, Sydney, NSW, Australia

Margaux Camuset, MD^1*, Alice Huault^1*, Audrey Grain, MD^1*, Beatrice Clemenceau, PhD^2*, Fanny Rialland, MD^3*, Caroline Thomas, M.D.^4*, Patrice Chevallier, MD, PhD^5,6, Marie-Christine Béné, PharmSciD, PhD^5,7* and Marion Eveillard^5,8*

¹Pediatric department, Nantes University Hospital, Nantes, France
²CRCINA, Nantes University Hospital, Nantes, France
³Service Onco-Hématologie Pédiatrique, Hôpital Mère-Enfant, Nantes University Hospital, Nantes, France
⁴Pediatric Department, Nantes University Hospital, Nantes, FRA
⁵CRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France
⁶Hematology Clinic, CHU Nantes, Nantes, France
⁷C.H.U. Hotel Dieu, Nantes, France
⁸Hematology Biology, Nantes University Hospital, Nantes, France

Xue Chen, MD^1,2*, Fang Wang, MD², Panxiang Cao, MS^2*, Xiaoli Ma, MD^2*, Lili Yuan, MD^2*, Yang Zhang, MD², Daijing Nie, MD^2*, Jiaqi Chen, MD^2*, Xiaosu Zhou^2*, Ming Liu, MD^2*, Zhixiu Liu, MD^2*, Mingyue Liu^2* and Hongxing Liu, MD^2,3,4

¹Division of Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Beijing, China
²Division of Laboratory Medicine, Hebei Yanda Lu Daopei Hospital, Langfang, China
³Beijing Lu Daopei Institute of Hematology, Beijing, China
⁴Division of Laboratory Medicine, Beijing Lu Daopei Hospital, Beijing, China