-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

621. Lymphoma—Genetic/Epigenetic Biology: Poster III

Program: Oral and Poster Abstracts
Type: Poster
Hematology Disease Topics & Pathways:
Adult, Follicular Lymphoma, bioengineering, Diseases, Lymphoma (any), biopsy, Hodgkin Lymphoma, Mantle Cell Lymphoma, Therapies, Non-Hodgkin Lymphoma, B-Cell Lymphoma, Biological Processes, DLBCL, T-Cell Lymphoma, Technology and Procedures, epigenetics, Lymphoid Malignancies, Study Population, Clinically relevant, genetic profiling, genomics, flow cytometry, immune mechanism, integrative -omics, NGS, microenvironment, molecular interactions, RNA sequencing, pathogenesis, WGS, pathways
Monday, December 7, 2020: 7:00 AM-3:30 PM

Jianbiao Zhou, MD, PhD,1,2*, Sabrina Hui Min Toh, BSc1*, Kalpnaa Balan, BSc1*, Tze King Tan, PhD1*, Yunlu Jia, MD3*, Jing Quan Lim, PhD4,5*, Choon Kiat Ong, PhD, BSc5,6, Soon Thye Lim, MBBS, MRCP5,7*, Tuan Zea Tan1*, Siok-Bian Ng1,8*, Takaomi Sanda, MD, PhD1,2 and Wee-Joo Chng, MBBS, PhD, FRCPath, FRCP1,9,10

1Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
2Department of Medicine, Yong Loo Lin School of Medicine, NUS, Singapore, Singapore
3Department of Surgical Oncology, Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou, China
4Lymphoma Genomic Translational Research Laboratory, Cellular and Molecular Research, National Cancer Centre Singapore, Singapore, Singapore
5Duke-NUS Medical School, Singapore, Singapore
6National Cancer Centre Singapore, Singapore, Singapore
7Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore
8Department of pathology, National University Cancer Institute of Singapore, National University Health System, Singapore, Singapore
9Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
10National University Cancer Institute of Singapore, Singapore, Singapore

Junji Koya, MD1*, Yuki Saito, MD1,2*, Takuro Kameda, M.D., Ph.D.3*, Yasunori Kogure, MD, PhD1*, Marni B McClure, MD, PhD1*, Sumito Shingaki, PhD, MD1*, Mariko Tabata, MD1,4*, Ayako Kamiunten, MD3*, Kotaro Shide, MD, PhD3, Kazuya Shimoda, MD, PhD3 and Keisuke Kataoka, MD, PhD1

1Division of Molecular Oncology, National Cancer Center Research Institute, Tokyo, Japan
2Department of Gastroenterology, Keio University School of Medicine, Tokyo, Japan
3Department of Gastroenterology and Hematology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan
4Department of Urology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Kim M Linton1*, Joanna M Oladipo, PhD2*, Nicholas Counsell, MSc3*, Janet Taylor, PhD4*, Cathy Burton, MBBChir, MA, MD, FRCPath4*, Rachel Oakley, PhD2*, Joanna Williams, PhD2*, Sally F Barrington, Prof, MD, PhD5*, Richard Byers, BSc, MSc, MBChB, PhD, FRCPath6*, Timothy Illidge, MD, PhD1* and John A. Radford, MD, FMedSci7*

1University of Manchester and The Christie NHS Foundation Trust, Manchester Cancer Research Centre and Manchester Academic Health Science Centre, Manchester, United Kingdom
2University of Manchester, Manchester Cancer Research Centre, Manchester, United Kingdom
3Cancer Research UK and UCL Cancer Trials Centre, UCL Cancer Institute, London, United Kingdom
4Haematological Malignancy Diagnostic Service, Leeds Cancer Centre, Leeds, United Kingdom
5Guy's and St. Thomas' Hospital and Kings College, London, Kent, United Kingdom
6University of Manchester, Manchester, United Kingdom
7The Christie NHS Foundation Trust, Manchester Cancer Research Centre and Manchester Academic Health Science Centre, Manchester, United Kingdom

Xiao-jie Liang1*, Na Yao2*, Dan Liu3*, Hai-ying Chen3*, Xin Xu3*, Jing-Wen Wang2*, Ken H. Young4 and Liang Wang2*

1First Clinical Medical College of Southern Medical University, Guangzhou, China
2Department of Hematology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
3The First School of Clinical Medicine, Guangdong Medical University, Zhanjiang, China
4Duke Medical Center and Duke Cancer institute, Duke University School of Medicine, Durham, NC

Concepción Fernández1,2*, Lierni Fernández1,3*, Joan Gibert, PhD4*, Leyre Bento5*, Blanca Sánchez-González6*, Rafael Ramos7*, Blanca Espinet, PhD8,9*, Ana Ferrer, MD, PhD10*, Mariana Paola Ferraro, MD6*, Juan F. Garcia11*, Carlos Montalban12*, Antonio Gutierrez13*, Beatriz Bellosillo, PhD1,14,15*, Lluís Colomo, MD, PhD16* and Antonio Salar, MD, PhD1,17*

1Group of Applied Clinical Research in Hematology. Cancer research program-IMIM, Barcelona, Spain
2Department of Pathology, Hospital del Mar, Barcelona, Spain
3Universitat Autònoma de Barcelona, Barcelona, Spain
4Hospital del Mar, Department of Pathology, Barcelona, Spain
5Hematology Department, Son Espases University Hospital, IdISBa, Palma, Spain
6Hematology Department, Hospital del Mar, Barcelona, Spain
7Pathology Department, Son Espases University Hospital, Palma, Spain
8Laboratori de Citogenètica Molecular, Servei de Patologia, Hospital del Mar, Barcelona, Spain
9Grup de Recerca Translacional en Neoplàsies Hematològiques, Programa de Recerca en Càncer, Institut Hospital del Mar d'Investigacions Mèdiques, Barcelona, Spain
10Laboratoris de Citologia Hematològica i Citogenètica, Servei de Patologia, Hospital del Mar. GRETNHE- Institut Hospital del Mar d’Investigacions Mèdiques (IMIM), Barcelona, Spain
11MD Anderson Cancer Center, Madrid, Spain
12Hematology, MD Anderson Cancer Center, Madrid, Spain
13Hematology Department, Son Espases University Hospital/IdISBa, Palma, Spain
14Pathology Department-IMIM, Universidad Pompeu Fabra, Hospital del Mar, Barcelona, Barcelona, ESP
15Pompeu Fabra University, Barcelona, Spain
16Hemopathology Section, Pathology department, Hospital del Mar, Barcelona, Spain
17Department of Haematology, Hospital del Mar, Barcelona, Spain

Yuping Li, PhD1*, Xiaoqian Liu, MD, PhD1,2*, Xuxiang Liu, PhD1*, Xiwei Wu, PhD3*, Alyssa Bouska, PhD4*, Waseem G. Lone, PhD4*, Chan-Wang J. Lio, PhD5*, Tyler Herek, BS, MS4, Logan Lee, BS1*, Gehong Dong, MD, PhD1*, Jinhui Wang, PhD3*, Chih-Hong Lou, PhD6*, Wei Qi, MD1,7*, Kunal Shetty, BS1*, Timothy W. McKeithan, MD, PhD1*, Javeed Iqbal, PhD4* and Wing (John) C. Chan, MD1

1Department of Pathology, City of Hope National Medical Center, Duarte, CA
2Department of Hematology, Affiliated Yantai Yuhuangding Hospital, Qingdao University, Yantai, China
3Department of Molecular and Cellular Biology, City of Hope National Medical Center, Duarte, CA
4Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE
5Division of Signaling and Gene Expression, La Jolla Institute for Allergy and Immunology, La Jolla, CA
6The Gene Editing and Viral Vector Core, Department of Shared Resources, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA
7Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China

Krysta M Coyle, PhD1*, Quratulain Qureshi, BSc2*, Prasath Pararajalingam, BSc3*, Nicole Thomas, BSc1*, Timothy E Audas, PhD2* and Ryan D Morin, PhD, BSc, MSc2,4

1Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada
2Simon Fraser University, Burnaby, BC, CAN
3Molecular Biology & Biochemistry, Simon Fraser University, Burnaby, BC, CAN
4Genome Sciences Centre, Vancouver, BC, Canada

Lucia Pedrosa Perez1,2*, Ismael Fernández-Miranda2,3*, David Perez Callejo4,5*, Cristina Quero6*, Marta Rodriguez7,8*, Paloma Martin-Acosta1,8*, Sagrario Gomez1*, Julia González-Rincón1,8*, Adrian Santos1*, Carlos Tarin1,9*, Juan F. Garcia8,10*, Francisco R García-Arroyo11*, Antonio Rueda12*, Francisca I Camacho13*, Monica Garcia-Cosio, MD14*, Ana Heredero1*, Marta Llanos15*, Manuela Mollejo8,16*, Miguel Piris-Villaespesa17*, José Gómez Codina, MD18*, Natalia Yanguas-Casás1*, Antonio Sánchez4*, Miguel A. Piris8,19*, Mariano Provencio4* and Margarita Sanchez-Beato20*

1Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Madrid, Spain
2PhD Program in Molecular Biosciences, Universidad Autónoma de Madrid, Madrid, Spain
3Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Majadahonda, ESP
4Hospital Universitario Puerta de Hierro, Madrid, Spain
5PhD Program in Medicine and Surgery, Universidad Autónoma de Madrid, Madrid, Spain
6Hospital Universitario Virgen de la Victoria, Málaga, Spain
7Pathology, Fundacion Jimenez Diaz, Madrid, Spain
8Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain
9Universidad CEU San Pablo, Madrid, Spain
10MD  Anderson Cancer Center, Madrid, Spain
11Complejo Hospitalario de Pontevedra, Pontevedra, Spain
12Hospitales Universitarios Regional y Virgen de la Victoria. IBIMA, Málaga, Spain
13HOSPITAL UNIVERSITARIO DE GETAFE, GETAFE, M, ESP
14Anatomical Pathology, Hospital Ramón y Cajal, Madrid, Spain
15Hospital Universitario De Canarias, La Laguna, S., ESP
16Hospital Virgen De La Salud, Toledo, ESP
17Hospital Universitario Ramón y Cajal, Madrid, Madrid, Spain
18Medical Oncology Department, Hospital Universitari i Politècnic La Fe, Valencia, Spain
19Fundacion Jimenez Diaz, Madrid, Spain
20Instituto de Investigación Sanitaria Puerta de Hierro-Segovia de Arana, Majadahonda, Spain

Joana M. Rodrigues1*, May Hassan, Msc.1*, Anna Porwit2*, Sara Ek, PhD, Professor3* and Mats Jerkeman, MD, PhD4

1Departament of Immunotechnology, Lund University, Lund, Sweden
2Lund University, Lund, SWE
3Lund University, Lund, Sweden
4Department of Oncology, Lund University and Skane University Hospital, Lund, Sweden

Firat Uyulur, MSc1*, Findlay Bewicke-Copley, PhD, MSc, BSc1, Chinedu Anthony Anene, PhD1*, Matthias Schlesner, PhD2*, Icgc MMML-Seq Project3*, Reiner Siebert, Prof. Dr. med.3*, Jessica Okosun, MD, PhD4*, Jude Fitzgibbon, PhD1* and Jun Wang, PhD1*

1Centre for Cancer Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom
2Bioinformatics and Omics Data Analytics, German Cancer Research Center (DKFZ), Heidelberg, Germany
3Institute of Human Genetics, Ulm University and Ulm University Medical Center, Ulm, Germany
4Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom

Xiaoqian Liu, MD, PhD1,2*, Yuping Li, PhD2*, Xuxiang Liu, PhD2*, Wei Qi, MD2,3*, Jibin Zhang2*, Kunal Shetty, BS2*, Javeed Iqbal, PhD4* and Wing C. Chan, MD2

1Department of Hematology, Affiliated Yantai Yuhuangding Hospital, Qingdao University, Yantai, China
2Department of Pathology, City of Hope National Medical Center, Duarte, CA
3Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China
4Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE

*signifies non-member of ASH