-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

616. Acute Myeloid Leukemia: Novel Therapy, excluding Transplantation: Poster III

Program: Oral and Poster Abstracts
Type: Poster
Hematology Disease Topics & Pathways:
Adult, AML, antibodies, apoptosis, Biological, CRS, Leukemia, bone marrow, CLL, CML, Diseases, Non-Biological, CAR-Ts, chemical interactions, CMML, Combinations, Elderly, Therapies, Adverse Events, checkpoint inhibitors, chemotherapy, MDS, Biological Processes, DNA damage, MPN, white blood cells, DNA repair, Technology and Procedures, Young Adult, epigenetics, immunotherapy, Lymphoid Malignancies, Study Population, Clinically relevant, Myeloid Malignancies, pharmacology, transplantation, vaccines, RNA sequencing
Monday, December 7, 2020: 7:00 AM-3:30 PM

Patrick K Reville, MD1, Hagop M. Kantarjian, MD2, Gautam Borthakur, MD2, Musa Yilmaz, MD3, Guillermo Montalban-Bravo, MD2*, Courtney D. DiNardo, MD, MSc4, Michael Andreeff, MD, PhD5, Naval Daver, MD6, Nitin Jain, MD7, Steven M. Kornblau, MD5, Elias Jabbour, MD2, Nicholas J. Short, MD2, Yesid Alvarado, MD3, Maro Ohanian, DO2*, Prithviraj Bose, MD2, Lucia Masarova, MD2*, Sa A Wang, MD8*, Rebecca S. S Tidwell, MS9*, Zeev E. Estrov, MD2, Guillermo Garcia-Manero, MD2, Marina Konopleva, MD, PhD2, Farhad Ravandi, MBBS2 and Tapan M. Kadia, MD10

1Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
3Department of Leukemia, MD Anderson Cancer Center, Houston, TX
4Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
5Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
6Department of Leukemia, The University of Texas, M.D. Anderson Cancer Center, Houston, TX
7Associate Professor of Medicine Department of Leukemia The University of Texas MD Anderson Cancer Center, Houston, TX
8Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
9Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
10Department of Leukemia, The University of Texas M.D. Anderson Cancer Center, Houston, TX

Jonathan A. Gutman, MD1, Amanda Winters, MD, PhD2, Maria L Amaya, MD, PhD1, Christine M. McMahon, MD3, Jeffrey Schowinsky, MD4*, Diana Abbott, PhD5*, Andrew Hammes, MS4*, Shanshan Pei, PhD4*, Brett M. Stevens, PhD6, Craig T. Jordan, PhD7, Clayton Smith, MD1 and Daniel A. Pollyea, MD8

1Division of Hematology, University of Colorado, Denver, CO
2Department of Pediatrics, University of Colorado, Denver, CO
3Division of Hematology, University of Colorado, Aurora, CO
4University of Colorado, Aurora, CO
5Department of Biostatistics and Bioinformatics, University of Colorado Denver, Colorado Springs, CO
6Division of Hematology, Department of Medicine, University of Colorado, Aurora, CO
7Division of Hematology, Department of Medicine, Univ. of Colorado, Denver, Aurora, CO
8Division of Hematology, University of Colorado Denver, Aurora, CO

Jessica Liegel, MD1, Richard M. Stone, MD2, Robert J. Soiffer, MD3, Dina Stroopinsky, PhD1*, Lina Bisharat4*, Maryam Rahimian4*, Emma Logan4*, Pavania Elavalakanar, MSc, BSc4*, Vincent T. Ho, MD2*, Rizwan Romee, MD5, Donna S. Neuberg, ScD6, Yiwen Liu6*, Lourdes M. Mendez, MD, PhD1, Ajoy L. Dias, MD1, Poorva Bindal, MD1*, Anita Koshy, MD1*, Shira Orr, PhD1*, Daniela Torres4*, Giulia Cheloni, PhD1*, Benjamin L. Ebert, MD, PhD3, Donald Kufe, MD2*, David E. Avigan, MD1 and Jacalyn Rosenblatt, MD1

1Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
2Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
3Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
4Beth Israel Deaconess Medical Center, Boston, MA
5Dana-Farber Cancer Institute, Boston, MA
6Department of Data Science, Dana-Farber Cancer Institute, Boston, MA

Norbert Vey, MD1, Corentin Orvain, MD, PhD2*, Christian Recher, MD, PhD3, Arnaud Pigneux, MD, PhD4*, Marc Bernard, MD5*, Anne Banos, MD6*, Pierre Peterlin, MD7*, Sylvain Chantepie, MD8*, Xavier Thomas, MD, PhD9, Cecile Pautas, MD10,11*, Claude Gardin12*, Emilie Lemasle, MD13*, Emmanuel Raffoux, MD14*, Romain Guieze, MD15*, Chantal Himberlin, MD16*, Clémence Loiseau, MD17*, Amine Belhabri, MD18*, Isabelle Luquet, MD19*, Christine Terré, PharmD, PhD20*, Martin Carre, MD21*, Claude Preudhomme, MD, PhD22, Eric Delabesse, MD, PhD23*, Karine Celli-Lebras, CRA24*, Ariane C Mineur, CRA25*, Jean-Francois Brasme, MD, PhD26*, Jean Francois Hamel, MD26*, Hervé Dombret, MD27 and Mathilde Hunault, MD PhD28,29*

1Onco-Hematology Department, Paoli-Calmette Cancer Institute, Marseille, France
2CHRU, Angers, France, angers, France
3Service d'hématologie IUCT Oncopole, Centre Hospitalier Universitaire de Toulouse, Toulouse, France
4Bordeaux Haut-Leveque University Hospital, Pessac, France
5Clinical Hematology, Rennes Univeristy Hospital, Rennes, France
6HOPITAL, COTE BASQUE, France
7Clinical Hematology, HOPITAL HOTEL DIEU ET HME, NANTES CEDEX 1, France
8IHBN, CHU Caen, Caen, FRA
9Centre Hospitalier Universitaire de Lyon-Sud, Lyon, France
10Hopital Henri Mondor, AP-HP, Creteil, France
11HOPITAL, CRETEIL, France
12Hematology, Avicenne Hospital, APHP, University Paris XIII, Bobigny, France
13Hematology Department, Henri-Becquerel Cancer Center, Rouen, France
14Hématologie clinique, Hôpital Saint-Louis, Paris, France
15CHU Estaing, Unit of adult cell therapy and clinical hematology, University Hospital of Clermont-Ferrand, Brookline, MA
16Hôpital Robert Debré, Reims, Reims, FRA
17University Versailles-Saint-Quentin-en-Yvelines, University Paris-Saclay, Paris Saclay, France
18Centre Leon Berard, Departement Oncologie Medicale, Lyon, France
19Hematology Biology, IUCT Oncopole Toulouse University Hospital, Toulouse, France
20Laboratory of Hematology, André Mignot Hospital, Le Chesnay, France
21Hematology, CHU Grenoble Alpes, La Tronche, France
22Centre de Biologie-Pathologie, CHU Lille, Lille, France
23Hematology Laboratory, Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France
24Saint-Louis University Hospital, Paris, France
25Bordeaux University Hospital, Pessac, France
26Centre de Recherche Clinique, CHU Angers, Angers, France
27Division of Hematology, EA3518 Saint-Louis Institute for Research, Hôpital Saint-Louis, APHP, University of Paris, Paris, France, Paris, France
28Clinical Hematology, Angers University Hospital, Angers, France
29Université d'Angers, Inserm, CRCINA, Angers, France

Justin M. Watts, MD1, Tara Lin, MD2, Eunice S. Wang, MD3, Alice S. Mims, MD4, Elizabeth H. Cull, MD5, Prapti Patel, MD6, Paul J. Shami, MD7*, Roland B. Walter, MD, PhD, MS8, Christopher R. Cogle9, Ruth A. Chenault, MS10*, Bret Macpherson, MSc, MBA10*, Allison Given Chunyk10*, Catherine J. McMahan10*, Jane A. Gross, PhD10* and Scott Stromatt, MD10*

1University of Miami Sylvester Comprehensive Cancer Center, Miami, FL
2University of Kansas Medical Center, Westwood, KS
3Roswell Park Comprehensive Cancer Center, BUFFALO, NY
4The Ohio State University Comprehensive Cancer Center, Columbus, OH
5Cancer Institute, Prisma Health, Piedmont, SC
6Simmons Comprehensive Cancer Center, Harold C Simmons Comprehensive Cancer Center, Dallas, TX
7Huntsman Cancer Institute, Salt Lake City, UT
8Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
9University of Florida, Gainesville, FL
10Aptevo Therapeutics, Seattle, WA

Chaoke Bu, MD1*, Zhiyong Peng, MD1*, Min Luo, PhD2*, Guangchao Li, PhD3* and Chunfu Li, MD1

1Nanfang-Chunfu Children's Institute of Hematology & Oncology, Taixin Hospital, Dongguan, China
2Guangzhou Bio-gene, GUANGZHOU, China
3Guangzhou Bio-gene, Guangzhou, China

Qi Zhang, PhD1*, Lina Han, PhD1, Alessia Lodi, PhD2*, Connie Weng1*, Vinitha Mary Kuruvilla, MSc1*, Antonio Cavazos, MSc1*, Helen Ma, MS1*, Abhishek Maiti1*, Yoko Tabe, MD, PhD3, Joseph R Marszalek, PhD4*, Stefano Tiziani2* and Marina Konopleva, MD, PhD5

1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Nutritional Sciences & Department of Pediatrics, Dell Medical School, The University of Texas at Austin, Austin, TX
3Department of Clinical Laboratory Medicine, Graduate School of Medicine, Juntendo University, Tokyo, Japan
4Institute for Applied Cancer Science and Center for Co-Clinical Trials, The University of Texas MD Anderson Cancer Center, Houston, TX
5Department of Leukemia, University of Texas, MD Anderson Cancer Center, Houston, TX

Alice S. Mims, MD1, Melhem Solh, MD2, Uma Borate3, Naveen Pemmaraju, MD4, Gautam Borthakur, MD5, Gail J. Roboz, MD6, Ben Powell, PhD7*, Paul Severson, PhD7*, Bernice Matusow7*, Jason Halladay, PhD7*, Ching Hsu, PhD8*, Paul Watkins7*, Chao Zhang, PhD7*, Jackie M. Walling, PhD, MD7, Athanasios C. Tsiatis, MD7 and Amy E. DeZern, MD9

1Arthur G. James Cancer Center Hospital, The Ohio State University Comprehensive Cancer Center, Columbus, OH
2Northside Hospital Cancer Institute, Atlanta, GA
3Division of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health and Science University, Portland, OR
4University of Texas, MD Anderson Cancer Center, Houston, TX
5Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
6Weill Medical College of Cornell University New York-Presbyterian Hospital, New York, NY
7Plexxikon Inc., Berkeley, CA
8Daiichi Sankyo Inc., Basking Ridge, NJ
9Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, Baltimore, MD

Christopher Fiore, PhD*, Michael J. Kelly, MD, MPH, MS*, Angela Volkert*, Li Zhou, PhD*, Kate Madigan, MD*, Matthew Eaton, PhD*, Graeme Hodgson, PhD*, David A. Roth, MD and Qing Kang-Fortner, PhD*

Syros Pharmaceuticals, Inc., Cambridge, MA

Guillermo Garcia-Manero, MD1, Uwe Platzbecker, MD2, Stefano R. Tarantolo, MD3, Stefanie Gropper4*, Chetasi Talati, MD5, Katharina S. Götze6, James Dugan, MD7*, Eric S. Winer, MD8, Elizabeth Martinez, PhD, DHSC, MSN9*, Christopher Lieberman10* and Reinhard von Roemeling, MD11

1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2Hematology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany
3Nebraska Cancer Specialist, Omaha, NE
4Marien Hospital Düsseldorf, Düsseldorf, Germany
5Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
6Department of Medicine III, Technical University of Munich, Munich, Germany
7Novant Health at Forsyth Medical Center, Winston-Salem, NC
8Department of Medical Oncology, Dana-Farber Cancer Institute, Boston
9Curis Inc., Lexington, MA
10Curis, Inc, Lexington, MA
11Curis, Inc., Lexington, MA

David A. Sallman, MD1, Hany Elmariah, MD, MS2, Kendra L. Sweet, MD, MS3*, Chetasi Talati, MD4, Asmita Mishra, MD5*, Linda L. Kelley, PhD6, Amy Lankford, PhD7*, Tim Chan, PhD8*, Rutul R Shah8*, Eric Padron, MD9, Rami S. Komrokji, MD10, Jeffrey E. Lancet, MD3, Helen Sabzevari, PhD8*, Marco L. Davila, MD, PhD1 and Nelli Bejanyan, MD11

1H. Lee Moffitt Cancer Center, Tampa, FL
2Department of Blood and Marrow Transplantation and Cellular Immunotherapy, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
3H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
4Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
5Department of Blood and Marrow Transplant and Cellular Immunotherapy, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
6Cell Therapy Facility, Moffitt Cancer Center, Tampa, FL
7Precigen, Inc., Germantown, MD
8Precigen, Inc, Germantown, MD
9Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
10H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
11Department of Blood and Marrow Transplantation and Cellular Immunotherapy, Moffitt Cancer Center, Tampa, FL

Weiguo Zhang, MD, PhD1, Kyung Hee Chang, PhD2*, Mahesh Basyal, BS2*, Yannan Jia2*, Lauren B Ostermann, BS2*, William E. Fogler, PhD3, John L. Magnani, PhD3, M Anna Zal, BS., MS2*, Tomasz Zal, PhD, MSc4 and Michael Andreeff, MD, PhD2

1Section of Molecular Hematology and Therapy, Department of Leukemia, U.T.M.D. Anderson Cancer Center, Houston, TX
2Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
3Glycomimetics, Inc., Rockville, MD
4Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX

Brian J. Ball, MD1*, Anthony S. Stein, MD2, Gautam Borthakur, MD3, Crystal Murray, RAC4*, Karin Kook, PhD4*, Kyle WH Chan, PhD5* and Eytan M. Stein, MD6

1Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Pasadena, CA
2Department of Hematology/HCT, City of Hope National Medical Center, Duarte, CA
3Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
4Salamandra, Bethesda, MD
5BioTheryX, Inc., San Diego, CA
6Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY

Courtney D. DiNardo, MD, MSc1, Daniel A. Pollyea, MD2, Marina Konopleva, MD, PhD3, Kyu Hong, MS4*, Tao Huang, PhD5*, An Song, PhD6*, Elizabeth Wieland, MS7*, Paul Woodard, MD4*, Charlene Liao, PhD6*, Chengcheng Zhang, PhD8*, Prapti Patel, MD9 and Ahmed Aribi, MD10*

1Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
2UCHealth University of Colorado Hospital, Denver, CO
3Department of Leukemia, University of Texas, MD Anderson Cancer Center, Houston, TX
4Immune-Onc Therapeutics, Inc, Palo Alto, CA
5Immune-Onc Therapeutics, Inc., PALO ALTO, CA
6Immune-Onc Therapeutics, Inc, PALO ALTO, CA
7Immune-Onc Therapeutics, Inc., Palo Alto, CA
8University of Texas-Southwestern Medical Center, Dallas, TX
9Simmons Comprehensive Cancer Center, Harold C Simmons Comprehensive Cancer Center, Dallas, TX
10City of Hope National Medical Center, Duarte, CA

Katharina Rothe, PhD1,2*, Xiaojia Niu, PhD1,2,3*, Min Chen, PhD2*, Rick Li4*, Sungeun Nam5*, Xiuyan Zhang6*, German Novakovskiy7*, Yehyeon Ahn8,9*, Shenshen Lai4*, Hong Zhang, PhD4*, Jun Yan4*, Hong Liu10*, Yun Zhao, PhD6*, Depei Wu, MD, PhD11, Yubin Ge, PhD12,13,14, Wyeth W. Wasserman9*, Calvin K. Yip15*, Zaihui Zhang, PhD4* and Xiaoyan Jiang, MD, PhD1,16

1Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada
2Terry Fox Laboratory, British Columbia Cancer, Vancouver, BC, Canada
3National Engineering Laboratory for AIDS Vaccine, Key Laboratory for Molecular Enzymology and Engineering, the Ministry of Education, School of Life Sciences, Jilin University, Changchun, China
4SignalChem Lifesciences Corporation, Richmond, Canada
5Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, BC, CAN
6Cyrus Tang Hematology Center, Soochow University, Suzhou, China
7University of British Columbia, Vancouver, BC, CAN
8Terry Fox Laboratory, British Columbia Cancer, Vancouver, Canada
9Department of Medical Genetics, University of British Columbia, Vancouver, Canada
10Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China
11Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China
12Karmanos Cancer Institute Wayne State Univ., Detroit, MI
13Oncology, Wayne State University School of Medicine, Detroit, MI
14Molecular Therapeutics Program, Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, MI
15Department of Biochemistry and Molecular Biology, University of British Columbia, Vancouver, Canada
16Terry Fox Laboratory, BC Cancer Research Centre, Vancouver, BC, Canada

Carina Sirochinsky, BA1*, Raymond Liang, PhD1*, Elina Shrestha, PhD1*, Ronen Ben Jehuda, PhD1* and Vladislav Sandler, PhD1,2

1Hemogenyx Pharmaceuticals LLC, Brooklyn, NY
2Department of Cell Biology, SUNY Downstate Medical Center, Brooklyn, NY

Lina Benajiba, MD, PhD1*, Hetty E. Carraway, MD, MBA2, Nada Hamad, MB.BS, FRACP, FRCPA3,4*, Eytan M. Stein, MD5, Costas K. Yannakou, MBBS (Hons), FRACP, FRCPA6*, Amy Burroughs7*, Scott Harris7*, Hayley Lane7*, Dorothy D. Nguyen, MD7*, Monic Stuart, MD, MPH7, Jesse Vargas, PhD8, Alexandre Puissant, PhD1*, Kimberly Stegmaier, MD9 and Courtney D. DiNardo, MD, MSc10

1APHP, INSERM U944, Institute of Hematology - St Louis Hospital, PARIS, France
2Taussig Cancer Institute, Cleveland Clinic, Department of Hematology and Medical Oncology, Cleveland, OH
3Department of Haematology, St. Vincent’s Hospital, Sydney, NSW, Australia
4University of New South Wales, Sydney, Australia
5Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
6Department of Molecular Oncology and Cancer Immunology, Epworth HealthCare, East Melbourne, VIC, Australia
7Cleave Therapeutics, Inc., San Francisco, CA
8Cleave Therapeutics, Inc., San Diego, CA
9Dana-Farber Cancer Institute, Boston, MA
10Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Rebecca M Richards, MD, PhD1, Feifei Zhao2*, Katherine A Murphy3*, Peng Xu, MD4*, Amy Fan5*, Elena Sotillo, PhD6*, Mads Daugaard7*, Htoo Zarni Oo7*, Jie Liu8*, Wan-Jen Hong9, Poul Sorensen10*, Robbie G. Majzner, MD6, Ravi Majeti11 and Crystal L. Mackall, MD12

1Department of Pediatrics, Stanford University, Palo Alto, CA
2Stanford University, Stanford
3Stanford University, Palo Alto, CA
4Stanford University School of Medicine, Palo Alto, CA
5Department of Medicine, Division of Hematology, Stanford University, Stanford, CA
6Department of Pediatrics, Stanford University School of Medicine, Palo Alto, CA
7University of British Columbia, Vancouver, BC, CAN
8Stanford University, Stanford, CA
9Genentech, Inc., South San Francisco, CA
10University of British Columbia/ BC Cancer Agency Research Centre, Vancouver, BC, CAN
11Department of Medicine, Division of Hematology, Cancer Institute, and Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA
12Center for Cancer Cell Therapy, Stanford University School of Medicine, Stanford, CA

Ralf Buettner, PhD1, Le Xuan Truong Nguyen, PhD1*, Corey James Morales, BA, BS1*, Lisa S Chen, PhD2*, Timothy Synold, PhD3*, Dinh Hoa Hoang, BS1*, Bin Amber Zhang, PhD1, Lucy Ghoda, PhD1*, Varsha Gandhi, PhD2, Vinod A. Pullarkat, MD1, Guido Marcucci, MD1 and Steven T. Rosen, MD1

1Gehr Family Center for Leukemia Research, City of Hope National Medical Center, Duarte, CA
2Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX
3Department of Cancer Biology, City of Hope, Duarte, CA

Miaomiao Liu1*, Yu Zhang2*, Weiyang Zheng1* and Qifa Liu, MD2

1Department of Hematology, Nanfang Hospital,Southern Medical University, Guangzhou, China
2Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China

Ahmed Aribi, MD1,2*, Anjali S Advani, MD3, William Donnellan, MD4, Amir T. Fathi, M.D.5, Marcello Rotta, MD6, Benjamin K. Tomlinson, MD7, Pankit Vachani, MD8*, Jay Yang, MD9, Phoenix Ho, MD10 and Guillermo Garcia-Manero, MD11

1Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA
2City of Hope National Medical Center, Duarte, CA
3Cleveland Clinic, Taussig Cancer Institute, Cleveland, OH
4Tennessee Oncology / Sarah Cannon Research Institute, Nashville, TN
5Massachusetts General Hospital , Harvard Medical School, Cambridge, MA
6Sarah Cannon Blood Cancer Network, Colorado Blood Cancer Institute, Denver, CO
7Case Western Reserve University, Cleveland, OH
8University of Alabama-Birmingham, Birmingham, AL
9Karmanos Cancer Institute, Detroit, MI
10Seattle Genetics, Bothell, WA
11Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Mohamed M. Hegazi, MD1*, John G. Harpel, MD, PhD2, Sara Miao2*, Dale Ludwig, PhD2*, Mark S. Berger, MD2 and Gary J. Schiller, MD3

1James Graham Brown Cancer Center, University of Louisville School of Medicine, Louisville, KY
2Actinium Pharmaceuticals, Inc., New York, NY
3David Geffen School of Medicine at University of California, Los Angeles, CA

Tatsuya Masuda, Master Degree1*, Hirohito Kubota, MD2*, Naoya Sakuramoto, Master Degree1*, Asuka Hada, Master Degree1*, Ayaka Horiuchi, Master Degree1*, Asami Sasaki, Master Degree1*, Kanako Takeda, Master Degree1*, Mizuho Takeda, Master Degree1*, Hidemasa Matsuo3*, Hiroshi Sugiyama, Ph.D.4*, Souichi Adachi, MD, PhD5 and Yasuhiko Kamikubo6*

1Graduate School of Medicine Kyoto university, Kyoto, Japan
2Department of Pediatrics, Kyoto University Hospital, Kyoto, Japan
3Department of Human Health Sciences, Kyoto University, Kizugawa, KYO, Japan
4Graduate School of Chemistry,Kyoto university, Kyoto, Japan
5Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan
6Department of Human Health Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan

Eytan M. Stein, MD1, Marina Konopleva, MD, PhD2, Raymond Gilmour, BSc, PhD3*, Anna M Szpurka, PhD3*, Elizabeth Hill, PhD3*, Renee Ward, MD, PhD4*, Hagop M. Kantarjian, MD2 and Courtney D. Dinardo, MD, MSc2

1Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
2Department of Leukemia, University of Texas, MD Anderson Cancer Center, Houston, TX
3Loxo Oncology at Lilly, Indianapolis, IN
4Loxo Oncology at Lilly, Stamford, CT

*signifies non-member of ASH