-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
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506. Hematopoiesis and Stem Cells: Microenvironment, Cell Adhesion, and Stromal Stem Cells: Poster III

Program: Oral and Poster Abstracts
Type: Poster
Hematology Disease Topics & Pathways:
iPSCs, cell regulation, Biological Processes, Technology and Procedures, Cell Lineage, hematopoiesis, microenvironment, RNA sequencing
Monday, December 7, 2020: 7:00 AM-3:30 PM
2747
Single-Cell Transcriptome of Early Hematopoiesis Guides Arterial Endothelium-Promoted Functional T Cell Generation from Human Pluripotent Stem Cells

Jun Shen1*, Yingxi Xu1*, Shuo Zhang1*, Shuzhen Lyu1*, Zack Wang, PhD2, Min Wang, MD3*, Xin Li4* and Tao Cheng1

1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China
2Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, MD
3State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
4School of Medicine, Sun Yat-sen University, Guangzhou, China
2748
M2 Macrophages, but Not M1 Macrophages, Support Megakaryopoiesis Via up-Regulating PI3K-AKT Pathway

Hong-Yan Zhao, PhD1*, Qi Wen, MD1*, Zhong-Shi Lyu1*, Shu-Qian Tang1*, Yuan-Yuan Zhang1*, Meng Lyu1*, Yu Wang2*, Lan-Ping Xu1*, Xiao-Hui Zhang1*, Yuan Kong1* and Xiao-Jun Huang1,3

1Peking University People’s Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing Key Laboratory of HSCT, Peking University, Beijing, China
2Peking University People’s Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematology Disease, Beijing Key Laboratory of Hematopoietic Stem Cell Transplantation, Beijing, China
3Peking-Tsinghua Center for Life Sciences, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China
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