Maria Solovey, PhD^1*, Klaus H. Metzeler, MD², Antonio Scialdone, PhD^1,3,4*, Maria Colomé-Tatché, PhD^1* and Frank Ziemann, MD^5*

¹Institute of Computational Biology, Helmholtz Zentrum München, Neuherberg, Germany
²Department of Internal Medicine III, Experimental Leukemia and Lymphoma Research (ELLF), University Hospital, LMU Munich, Munich, Germany
³Institute of Epigenetics and Stem Cells, Helmholtz Zentrum München, Neuherberg, Germany
⁴Institute of Functional Epigenetics, Helmholtz Zentrum München, Neuherberg, Germany
⁵Department of Internal Medicine III, Experimental Leukemia and Lymphoma Research (ELLF), LMU University Hospital, Munich, Germany

Yasutaka Hayashi^1,2*, Kimihito Cojin Kawabata, MD, PhD^1,3*, Yosuke Tanaka, PhD^1*, Yasufumi Uehara, MD, PhD^4*, Shigeru Kiryu, MD, PhD^5*, Yasunori Ota, MD, PhD^6*, Yusuke Yoshioka, PhD^7*, Yo Mabuchi, PhD^8*, Tatsuki Sugiyama, MD, PhD^9*, Keiko Mikami, MSc^1*, Moe Tamura, MSc^1*, Tsuyoshi Fukushima, MD, PhD^1*, Shuhei Asada, MD, PhD^1,10*, Reina Takeda, MD, PhD^1*, Yuya Kunisaki, MD, PhD^4*, Tomofusa Fukuyama, MD, PhD¹, Susumu Goyama, MD, PhD^1*, Kazuaki Yokoyama, MD, PhD¹¹, Arinobu Tojo, MD, PhD¹¹, Yoshio Katayama, MD, PhD¹², Fumio Arai, PhD⁴, Takashi Nagasawa, MD, PhD^9*, Takahiro Ochiya, Ph.D^7*, Daichi Inoue, MD, PhD² and Toshio Kitamura, MD, PhD¹

¹Division of Cellular Therapy, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
²Department of Hematology-Oncology, Institute of Biomedical Research and Innovation, Foundation for Biomedical Research and Innovation at Kobe, Kobe, Japan
³Department of Medicine, Division of Hematology-Medical Oncology, Weill-Cornell Medical College, Cornell University, New York, NY
⁴Department of Stem Cell Biology and Medicine/Cancer Stem Cell Research, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
⁵Department of Radiology, International University of Health and Welfare, School of Medicine, Nasushiobara, Japan
⁶Department of Pathology, Research Hospital, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
⁷Department of Molecular and Cellular Medicine, Institute of Medical Science, Tokyo Medical University, Tokyo, Japan
⁸Department of Biochemistry and Biophysics, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, Tokyo, Japan
⁹Laboratory of Stem Cell Biology and Developmental Immunology, Graduate School of Frontier Biosciences and Graduate School of Medicine, WPI Immunology Frontier Research Center, Osaka University, Osaka, Japan
¹⁰The Institute of Laboratory Animals, Tokyo Women’s Medical University, Tokyo, Japan
¹¹Department of Hematology/Oncology, Research Hospital, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
¹²Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan

Guohuan Sun^1*, Dan Huang^2*, Xiaoxin Hao^2*, Xiaoxiao He^2*, Zhaofeng Zheng^1*, Chiqi Chen^2*, Zhuo Yu^2*, Li Xie^2*, Shihui Ma, MD^1*, Ligen Liu², Bo Zhou^3*, Hui Cheng^1*, Junke Zheng^2* and Tao Cheng⁴

¹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
²Hongqiao International Institute of Medicine, Shanghai Tongren Hospital, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education; Shanghai Jiao Tong University School of Medicine; State Key Laboratory of Experimental Hematolo, Shanghai, China
³State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China
⁴State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China