Anne Olazabal-Herrero, PhD^1,2*, Allison M. Green^3*, Xiaoyong Chen^4*, Patrick Sung, PhD^5*, Manoj M Pillai, MD⁶ and Gary M. Kupfer, MD⁷

¹Department of Oncology, Georgetown University, Washington, DC
²Department of Internal Medicine, Yale University School of Medicine, New Haven, CT
³Department of Pediatrics, Yale University School of Medicine, New Haven, CT
⁴Yale, New Haven, CT
⁵University of Texas Health Sciences Center San Antonio, San Antonio
⁶Department of Internal Medicine, Section of Hematology, Yale University School of Medicine, New Haven, CT
⁷Department of Oncology, Georgetown University, washington, DC

Marena R. Niewisch, MD^1*, Neelam Giri, MD², Lisa J. McReynolds, MD, PhD³, Sonia Bhala, BS^4*, Rotana Alsaggaf, PhD, MS^1*, Blanche P. Alter, MD, MPH¹ and Sharon A. Savage, MD¹

¹Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD
²Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD
³NCI, National Institutes of Health, Bethesda, MD
⁴Rutgers Robert Wood Johnson Medical School, Piscataway, NJ

Simona Pagliuca, MD^1,2, Carmelo Gurnari, MD^1,3*, Hassan Awada, MD¹, Cassandra M Kerr, MS^1*, Bhumika J. Patel, MD⁴, Laila Terkawi^1*, Misam Zawit, MBBS^1*, Sunisa Kongkiatkamon, MD^1*, Pedro H Prata, MD⁵, Ashwin Kishtagari, MBBS¹, Adam Wahida^6*, Thomas Laframboise, PhD^7*, Valeria Visconte, PhD¹, Regis Peffault De Latour, MD, PhD^5,8* and Jaroslaw P. Maciejewski, MD, PhD⁹

¹Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH
²Université de Paris, Paris, France
³Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
⁴Leukemia Program, Department of Hematology and Medical Oncology, Cleveland Clinic, Cleveland, OH
⁵Department of Hematology and Transplantation, Hôpital Saint Louis, Paris, France
⁶MLL Munich Leukemia Laboratory, Munich, Germany
⁷Genetics and Genome Sciences Department, Case Western Reserve University, Cleveland, OH
⁸French Reference Center for Aplastic Anemia and Paroxysmal Nocturnal Hemoglobinuria, Assistance Publique – Hôpitaux de Paris, Université de Paris, Paris, France
⁹Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH

Carmelo Gurnari, MD^1,2*, Simona Pagliuca, MD^2,3, Cassandra M Kerr, MS^2*, Hassan Awada, MD², Sunisa Kongkiatkamon, MD^2*, Laila Terkawi^2*, Neetha Parameswaran, PhD², Misam Zawit, MBBS^2*, Adam Wahida^4*, Valeria Visconte, PhD² and Jaroslaw P. Maciejewski, MD, PhD⁵

¹Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
²Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH
³Université de Paris, Paris, France
⁴MLL Munich Leukemia Laboratory, Munich, Germany
⁵Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH

Jean-Alain Martignoles^1*, Pierre Hirsch, MD, PhD^2*, Blandine Beaupain^3*, Thomas Longval, MD^4*, Nawa Hachem, MsC^5*, Mira El-Khoury, PhD^6*, Sophie Kaltenbach^7*, Jean Soulier, MD, PhD⁸, Thierry Leblanc, M.D.^9,10*, Pierre Simon Rohrlich, MD PhD^11*, Eric Jeziorski, MD PhD^12*, Isabelle Meyts^13*, Dalila Adjaoud, MD^14*, Vincent Barlogis, M.D., Ph.D.^15*, Marlène Pasquet, M.D., Ph.D.^16*, Laetitia Largeaud^17*, Flore Sicre de Fontbrune^18*, Claire Fieschi, MD, PhD^19*, Virginie Gandemer, MD, PhD^20*, Nathalie Aladjidi, MD^21*, Fanny Fouyssac, MD^22*, Guy Leverger, M.D.^23*, Wadih Abou Chahla, M.D.^24*, Stephane Blanche, MD^25*, Despina Moushous, MD, PhD^26*, Aline Moignet Autrel, MD^27*, Yves Bertrand, M.D.^28,29*, Cecile Renard^29,30*, Pascale Flandrin-Gresta, MD^31,32*, Jean Louis Stephan, MD PhD^33*, Olivier Tournilhac, MD, PhD^34,35*, Liana Carausu^36*, Frederic Millot, M.D.^37*, Marielaure Couec, MD^38*, Claude Preudhomme, MD, PhD^39,40,41,42, Hélène Lapillonne, MD, PhD^43*, Vahid Asnafi, MD, PhD^44,45,46*, Patrick Revy^47*, Christine Bellanne-Chantelot, PhD, PharmD^48,49*, Francois Delhommeau, MD, PhD^2,50* and Jean Donadieu, MD, PhD⁵¹

¹Sorbonne Université, UMRS 938 "hematopoietic and Leukemic Development", A, Paris, FRA
²APHP, Hôpital Saint Antoine, Service d'hématologie Biologique, Paris, France
³Registre francais des neutropénies chroniques, HôPital Trousseau, France, FRA
⁴APHP hopital saint antoine, Laboratoire hématologie, Paris, France
⁵laboratoire d’hématologie Saint-Antoine, Sorbonne Université CRSA UMRS938, paris, France
⁶Gustave Roussy, INSERM, UMR1170, Villejuif, France
⁷INSERM U768, Paris, FRA
⁸Hematology Laboratory and INSERM U944, Hopital Saint-Louis Centre Hayem 2ETG, Paris, France
⁹Pediatric Hematology Unit, Robert-Debré Hospital, AP-HP, Paris, France
¹⁰French Reference Center for Aplastic Anemia, Paris, France
¹¹CHU L'Archet, Nice, FRA
¹²Pediatrics, CHU Montpellier, Montpeller, FRA
¹³UZ Leuven, Leuven, BEL
¹⁴hemato oncologie pédiatrique, CHU de Grenoble, Grenoble, France
¹⁵Department of Pediatric Hematology, La Timone Hospital, AP-HM, Marseille, France
¹⁶Pediatric Oncology Immunology Hematology Unit, Children’s hospital, CHU de Toulouse, Toulouse, France
¹⁷Institut Universitaire Du Cancer De Toulouse-Oncopole, Toulouse, FRA
¹⁸Centre de Référence Aplasie Médullaire, Service d’Hématologie Greffe, Assistance Publique des Hôpitaux de Paris, Hôpital Saint-Louis, Paris, France
¹⁹Service d’Immunologie clinique, Hôpital Saint-Louis, AP-HP, Paris, France
²⁰CHU Hopital Sud, Rennes, FRA
²¹12. Unité d’Hématologie Pédiatrique, CIC 1401 INSERM CICP, CHU Bordeaux, Bordeaux, France
²²hemato oncologie pédiatrique, CHU de Nancy, Nancy, France
²³Pediatric Hematology Oncology Immunology Department, Armand-Trousseau University Hospital, AP-HP, Paris, France
²⁴Department of Pediatric Hematology, Jeanne de Flandre Hospital, CHRU de Lille, Lille, France
²⁵Department of Pediatric Immunology, Hematology and Rheumatology, Necker Enfants Malades University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France
²⁶Unité d'immuno hématologie rhumatologie pédiatrique, APHP université de Paris Hopital Necker enfants malades, Paris, France
²⁷Clinical Hematology Department, Rennes CHU, Rennes, France
²⁸Institute of Pediatric Hematology and Oncology, Civil Hospital of Lyon, Claude Bernard University, Lyon, France
²⁹Claude Bernard University, Lyon 1, Lyon, France
³⁰IHOPE, Civil Hospital of Lyon, Lyon, France
³¹Hopital Saint Antoine, Laboratoire d'Hématologie, AP-HP Hôpital Saint Antoine, Sorbonne Universités, UPMC Univ Paris 06, UMR_S 938, CDR Saint-Antoine,, paris, France
³²Laboratoire d'Hématologie, CHU de Saint-Etienne, Saint-Priest-en-Jarez, France
³³Pediatric Hemato-Oncology, CHU de Saint Etienne , Hôpital Nord, Saint-priest-en-Jarez, FRA
³⁴Service d'Hématologie Clinique et Thérapie Cellulaire, CHU, Université Clermont Auvergne EA7453 Chelter CIC-1405, Clermont-Ferrand, FRA
³⁵Hématologie Clinique Adulte et Thérapie Cellulaire, CHU Hotel Dieu Hématologie, Clermont-Ferrand, France
³⁶CHRU Brest, Brest, FRA
³⁷Department of Pediatric Hematology-Oncology, University Hospital Poitiers, Poitiers, France
³⁸hemato oncologie Pédiatrique, CHU Nantes, nantes, France
³⁹Institut de Recherche contre le Cancer de Lille, UMR-S1172, Lille, France
⁴⁰Centre de Biologie-Pathologie, CHU Lille, Lille, France
⁴¹UMR-S 1172, INSERM, Lille, France
⁴²Cancer Research Institute, INSERM Unité Mixte de Recherche (UMR)-S 1172, F-59000 Lille, CHU Lille, Laboratory of Hematology, F-59000 Lille, Lille, France
⁴³Pediatric Hematology and Oncology Department, Hôpital Armand Trousseau, Paris, France
⁴⁴INSERM U1151, Université Paris Descartes Sorbonne Cité, Paris, France
⁴⁵Laboratory of Onco-Hematology, Hôpital Necker Enfants-Malades, APHP, Paris, France
⁴⁶Biological Hematology, Necker University Hospital, Paris, France
⁴⁷Institut Imagine, Paris, FRA
⁴⁸Hopital Pitié Salpétriére APHP, Département de Génétique, AP-HP Hôpital Pitié- Salpêtrière, UPMC Univ Paris 06, Paris, France
⁴⁹Département de Neurologie, Hôpital Pitié-Salpêtrière, Paris, France
⁵⁰INSERM U938, Paris, France
⁵¹Service d'Hémato-Oncologie Pédiatrique, Hopital Trousseau, Paris, Cedex, France

Bruno Quintino Oliveira, brunoqolvr@gmail.com^1*, Bárbara Santana, PhD^1*, Luiz Fernando Bazzo Catto, MD, PhD^1*, Maria Florencia Tellechea, PhD^1*, Priscila Santos Scheucher, PhD^1*, Phillip Scheinberg, MD² and Rodrigo T. Calado, MD, PhD¹

¹Department of Medical Imaging, Hematology, and Clinical Oncology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil
²Division of Hematology, Hospital A Beneficência Portuguesa, Sao Paulo, Brazil

Noriaki Tsuji, MD^1*, Kohei Hosokawa, MD, PhD ¹, Ryota Urushihara, MD^1*, Mikoto Tanabe, MD^1*, Hiroyuki Takamatsu, MD, PhD¹, Ken Ishiyama, MD, PhD¹, Hirohito Yamazaki, MD, PhD^2* and Shinji Nakao, MD, PhD¹

¹Department of Hematology, Kanazawa University, Kanazawa, Japan
²Division of Transfusion Medicine, Kanazawa University Hospital, Kanazawa, Japan

Hillard Lazarus^1*, Carolina Escobar, MD^2*, Leland Metheny III, MD^1,3, Joseph P. McGuirk, DO^4,5, Tsila Zuckerman, MD^6,7, Mark Litzow, MD⁸, Scott D. Rowley, MD⁹, Racheli Ofir, PhD^10*, Liran Shani, MD^11* and Jacob M. Rowe, MB, BS¹²

¹Case Western Reserve University, Cleveland, OH
²Texas Oncology-Baylor Charles A. Sammons Cancer Center Blood and Marrow Transplant, Dallas, TX
³Adult Hematologic Malignancies & Stem Cell Transplant Section, University Hospitals Seidman Cancer Center, Cleveland, OH
⁴The University of Kansas Cancer Center, Westwood, KS
⁵Division of Hematologic Malignancies & Cellular Therapeutics, University of Kansas Medical Center, Kansas City, KS
⁶Department of Hematology and Bone Marrow Transplantation, Rambam Health Care Campus, Haifa, Israel
⁷The Ruth and Bruce Rappaport Faculty of Medicine, Technion – Israel Institute of Technology, Haifa, Israel
⁸Division of Hematology, Mayo Clinic, Rochester, MN
⁹John Theurer Cancer Center, Myeloma and Lymphoma Divisions, NNJCA, Hackensack, NJ
¹⁰Pluristem LTD, HAIFA, Israel
¹¹Pluristem ltd, HAIFA, Israel
¹²The Ruth and Bruce Rappaport Faculty of Medicine, Shaare Zedek Medical Center, Jerusalem, Israel

Michelle Nash, MD^1*, Adrianna Vlachos, MD², Marcin W. Wlodarski, MD, PhD³ and Jeffrey M Lipton, MD, PhD⁴

¹Cohen Children's Medical Center, Commack, NY
²Feinstein Institute of Medical Research, Cohen Children's Medical Center, Manhasset, NY
³St. Jude Children's Research Hospital, Memphis, IN
⁴Hematology/Oncology and Stem Cell Transplantation, Cohen Children's Medical Center of NY, New Hyde Park, NY

Yeon Jung Lim, MD^1,2*, Omri Avraham Arbiv^3*, Melanie Evelyn Kalbfleisch^4*, Mohammed Al Nuaimi, MD^5*, MacGregor Steele, MD, FRCPC⁶, Geoff D.E. Cuvelier, MD⁷, Tal Schechter-Finkelstein, MD⁸, Bozana Zlateska, MD, MSc^9*, Michaela Cada, MD, FRCPC, FAAP, MPH¹⁰ and Yigal Dror, MD, FRCPC¹⁰

¹Program in Genetics and Genome Biology, Research Institute, Hospital for Sick Children, Toronto, Canada
²Department of Pediatrics, College of Medicine, Chungnam National University, Daejeon, Korea, Republic of (South)
³Marrow Failure and Myelodysplasia Program, Division of Haematology/Oncology, Genetics and Genome Biology Program, Research Institute, The Hospital for Sick Children and the University of Toronto, Toronto, ON, Canada
⁴Marrow Failure and Myelodysplasia Program, Division of Haematology/Oncology, Department of Paediatrics, Genetics and Genome Biology Program, The Hospital for Sick Children and the University of Toronto, Toronto, ON, Canada
⁵Marrow Failure and Myelodysplasia Program, Division of Haematology/Oncology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
⁶Cumming School of Medicine, Alberta Children's Hospital, University of Calgary, Calgary, AB, Canada
⁷Pediatric Blood and Marrow Transplant, Manitoba Blood and Marrow Transplant Program, CancerCare Manitoba, University of Manitoba, Winnipeg, MB, Canada
⁸The Hospital for Sick Children, Toronto, Canada
⁹Department of Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada
¹⁰Marrow Failure and Myelodysplasia Program, Division of Hematology/Oncology, Department of Pediatrics, Hospital for Sick Children, Toronto, ON, Canada

Rong Fu, PhD^1,2*, Yang Li^1*, Zhaoyun Liu^3*, Chunyan Liu^4*, Hui Liu^2* and Zonghong Shao, PhD²

¹Tianjin Medical University General Hospital, Tianjin, China
²Department of Hematology, Tianjin Medical University General Hospital, Tianjin, China
³Tianjin Medical University General Hospital, tianjin, China
⁴Tianjin Medical University Genernal Hospital, Tianjin, China

Aye Aye Gyi, MBBS, MMedSc, MRCP, DrMedSc, FRCP^1*, Khin Thida Htut, MBBS MMedSc DrMedSc^2*, Yin Nwe Han, MD^3*, Mie Mie Khine, MD^4,5*, Hnin Mya Thandar, MD^6* and Yi Mon Thant, MBBS, MMedSc^7*

¹Department of Clinical Haematology, Professor and Head, North Okkalapa General and Teaching Hospital, Yangon, Myanmar
²Department of Clinicla Haematology, North Okkalapa General and Teaching Hospital, Yangon, Myanmar
³Department of Clinical Haematology, North Okkalapa General & Teaching Hospital, Yangon, MMR
⁴Department of Clinical Haematology, Hematology, Yangon, Yangon, Myanmar
⁵Department of Clinical Haematology, North Okkalapa General and Teaching Hospital, Yangon, Myanmar
⁶North Okkalapa General and Teaching Hospital, Yangon, Myanmar
⁷Clinical Haematology, North Okkalapa General and Teaching Hospital, Yangon, Myanmar

Benjamin Chin-Yee, MD¹, Indermohan S. Sandhu, MBBS, MD^2*, Ivan Pacheco, MD, PhD, FRCPC^2,3* and Selay Lam, MD, BSc, FRCPC⁴

¹Division of Hematology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London Health Sciences Centre, Toronto, ON, Canada
²Grey Bruce Health Services, Owen Sound, ON, Canada
³Department of Pathology and Laboratory Medicine, Western University, London, ON, Canada
⁴Division of Hematology, Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London Health Sciences Centre, London, ON, Canada