62nd ASH Annual Meeting and Exposition: 331. Pathophysiology of Thrombosis: Poster I

Oral and Poster Abstracts
Poster

Adult, anticoagulant drugs, viral, autoimmune disorders, Coronaviruses, SARS-CoV-2/COVID-19, Non-Biological, Bleeding and Clotting, Diseases, Therapies, Adverse Events, Pediatric, coagulant drugs, Biological Processes, Thrombosis, Immune Disorders, Young Adult, Lymphocytopenia, Study Population, Thromboembolism, Clinically relevant, Thrombotic Disorders, inflammation, VTE, iron metabolism, iron transport, microenvironment, pathogenesis

879

Thrombotic Events in COVID-19 Patients and Its Comparison with Other Non-Sars-Cov-2 Respiratory Viruses

Jing Yuan Tan¹^*, Chuen Wen Tan, MBBS, FRCPath, MRCP²^*, Wan Hui Wong, BSc, PhD²^*, Edwin Philip Conceicao, BSc (Nursing)²^*, Ian Matthias Ng, MBBS²^*, May Anne Cheong, MBBS, MRCP²^*, Jenny Guek-Hong Low, MBBS, MPH^3,4^*, Heng Joo Ng, MBBS⁵^* and Lai Heng Lee, MBBS, FRCP²

¹Singapore General Hospital, Singapore, SGP
²Singapore General Hospital, Singapore, Singapore
³Department of Infectious Diseases, Singapore General Hospital, Singapore, SGP
⁴Programme in Emerging Infectious Diseases, Duke-NUS, Singapore, Singapore
⁵Department of Haematology, Singapore General Hospital, Singapore, Singapore, Singapore

880

Derivation and Validation of a Predictive Score for Disease Worsening Inpatients with COVID-19

Grigoris Gerotziafas, MD, PhD^1,2^*, Patrick Van Dreden, PhD³, Loula Papageorgiou^4,5^*, Theodoros N Sergentanis, MD, PhD⁶^*, Meletios-Athanasios Dimopoulos⁷ and Ismail Elalamy, MD, PhD⁸

¹Sorbonne Universities, Faculty of Medicine, Cancer, Haemostasis and Angiogenesis Research Group, INSERM U938, Institut Universitaire de Cancérologie,, Paris, France
²Service d'hematologie biologique Hôpital Tenon APHP, Thrombosis center, Paris, France
³Clinical Research, Stago, Gennevilliers, France
⁴Cancer Biology and Therapeutics, INSERM U938, Institut Universitaire de Cancérologie (IUC), Université Pierre et Marie Curie (UPMC), Sorbonne Universities, Paris. Faculté de Médecine Pierre et Marie Curie, Paris, France
⁵Department of haematology, Tenon University Hospital Assistance Publique Hopital de Paris, Paris, France
⁶Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
⁷Department of Clinical Therapeutics,, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
⁸Hopital Tenon, Paris, France

881

Children and Young Adults Admitted to a NYC Children’s Hospital Had a Similar Rate of Severe COVID-19 Coagulopathy As That Reported in Older Adults

William Beau Mitchell, MD¹, Jennifer G. Davila, MD², Janine Keenan, RN³^*, Jenai Jackson⁴^*, Adit Tal, MD¹, Kerry A Morrone, MD⁵, Ellen J Silver, PhD⁶^*, Sarah H. O'Brien, MD⁷ and Deepa Manwani, MD⁸

¹Children's Hospital at Montefiore, Bronx, NY
²The Children's Hospital At Montefiore-Aecom, Bronx, NY
³Division of Hematology/ Oncology, The Children’s Hospital at Montefiore, Bronx, NY
⁴Albert Einstein College of Medicine, Bronx, NY
⁵Children's Hospital At Montefiore, Bronx, NY
⁶Albert Einstein College of Medicine, Bronx
⁷Nationwide Children's Hospital, Columbus, OH
⁸Division of Pediatric Hematology/Oncology, Department of Pediatrics, Children's Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY

882

Factors Associated with Catheter-Related Thrombosis in Autologous Stem Cell Transplant Patients: Can We Predict Risk?

Annie M. Jacobsen, MD¹, Qing Cao, MS²^*, Veronika Bachanova, MD, PhD³ and Surbhi Shah, MD²

¹Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN
²University of Minnesota, Minneapolis, MN
³Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN

883

Low Rate of Thrombosis in Mexican Patients with COVID-19 Infection. a Benefit of Higher Doses Anticoagulants or a Sub Diagnosis?

Félix Gibrant Marquez, MD¹, Santiago Riviello-Goya, MD²^*, Angel Gabriel Vargas Ruiz³^*, Edgar Ortíz Brizuela, MD⁴^*, Fernando Gil López, MD⁵^*, Alfredo Gutierrez Marín, MD⁶^*, María Fernanda Gonzalez Lara, MDs⁷^*, Alfredo Ponce de Léon Garduño, MD⁸^*, José Sifuentes Osornio, PhD⁵^* and Juan Rangel-Patiño, MD⁹

¹Hematology and Oncology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, DF, Mexico
²Internal Medicine Department, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, DF, Mexico
³Hematology Oncology Deparment, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Tlalpan, AG, MEX
⁴Infectious Disease, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, DF, Mexico
⁵Medicine, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, DF, Mexico
⁶Critical Care Unit, Insituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, DF, Mexico
⁷Infectious Diseases, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, DF, Mexico
⁸Infectiuos Diseases, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, DF, Mexico
⁹Department of Hematology and Oncology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

884

Peripherally Inserted Central Catheter (PICC) Related Deep Venous Thrombosis: A Retrospective Cohort Study on Incidence and Risk Factors in a Single Center

June Iriondo¹^*, Oihane Iñarra²^*, Beatriz Sarriegui¹^*, Nekane Sanz¹^*, Maialen Lasa¹^*, Maria Aranzazu Aguirre¹^*, Cristina Sarasqueta³^*, Jesus Blanco¹^*, Maria Rua¹^*, Gabriela Yurrita¹^*, Sergio Martin¹^*, Jennifer Gomez⁴^*, Maite Centeno¹^*, Maria Araiz¹^*, Camino Del Rio¹^* and Izaskun Ceberio¹^*

¹Donostia University Hospital, Donostia, Spain
²University of the Basque Country, Donostia, Spain
³Biodonostia Health Research Institute, Donostia, Spain
⁴Onkologikoa, Donostia, Spain

885

Application of Thrombomodulin-Thrombin Generation to Diverse Abnormalities of the Protein C System

Marilyn J Manco-Johnson, MD¹, Linda Jacobson, BS²^*, Dianne Thornhill, PhD²^*, Christine Baird, BS³^* and Beth Boulden Warren, MD MS MSCS⁴^*

¹University of Colorado Anschutz Medical Campus, Aurora, CO
²Hemophilia and Thrombosis Center, University of Colorado Anschutz Medical Campus and Children's Hospital Colorado, Aurora, CO
³Hemophilia and Thrombosis Center, University of Colorado Anschutz Medical Campus, Aurora, CO
⁴Hemophilia and Thrombosis Center, University of Colorado Anschutz Medical Center, Aurora, CO

886

Thrombin Generation and D-Dimer Significantly Predict for Early Disease Progression and Mortality in Patients with Gastrointestinal Cancer

Marina Pesenti¹^*, Marina Marchetti¹^*, Cinzia Giaccherini¹^*, Cristina Verzeroli¹^*, Laura Russo¹^*, Giampietro Gasparini²^*, Roberta Sarmiento²^*, Luigi Celio³^*, Giovanna Masci⁴^*, Sara Gamba¹^*, Patricia Gomez-Rosas, MD^1,5^*, Nadia FJ Schillaci¹^*, Silvia Bolognini¹^*, Carmen J Tartari¹^*, Erika Diani¹^*, Alfonso Vignoli¹^*, Carlo Tondini⁶^*, Sandro Barni⁷^*, Francesco Giuliani⁸^*, Fausto Petrelli⁷^*, Andrea D'Alessio⁹^*, Filippo De Braud³^*, Armando Santoro¹⁰^*, Roberto Labianca¹¹^* and Anna Falanga, MD^1,12

¹Immunohematology and Transfusion Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy
²Oncology Unit, Hospital San Filippo Neri, Rome, Italy
³Oncology Unit, IRCCS National Cancer Institute, Milan, Italy
⁴Oncology Unit, IRCCS Humanitas Institute, Rozzano, Milan, Italy
⁵Hematology Service, Hospital General Regional Tecamac IMSS, Mexico, Mexico
⁶Oncology Unit, Hospital Papa Giovanni XXIII, Bergamo, Italy
⁷Oncology Unit, Hospital Treviglio-Caravaggio, Treviglio, Bergamo, Italy
⁸Oncology Unit, IRCCS Cancer Institute Giovanni Paolo II, Bari, Italy
⁹Medical Oncology and Internal Medicine, Policlinico San Marco, Zingonia, Bergamo, Italy
¹⁰Department of Biomedical Sciences, Humanitas Clinical and Research Center IRCCS Rozzano-Milano, Milan, Italy
¹¹Department of Oncology Bergamo Province, Hospital Papa Giovanni XXIII, Bergamo, Italy
¹²School of Medicine, University of Milano Bicocca, Milano, Italy

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^*signifies non-member of ASH

331.P1.24 331. Pathophysiology of Thrombosis: Poster I