Agnes Y. Lee, MD, MSc¹, Pieter W. Kamphuisen, MD, PhD^2*, Rupert Bauersachs, MD, PhD^3,4*, Karen Turpin, BScN, MSc^5*, Jes Birger Hansen^6* and Alok A Khorana, MD⁷

¹Department of Hematology, University of British Columbia, Vancouver, BC, Canada
²University Medical Center Groningen, Groningen, NLD
³Department Vascular Medicine, Darmstadt Hospital, Darmstadt, DEU
⁴Center of Thrombosis and Haemostasis, University of Mainz, Mainz, Germany
⁵Medical Affairs, Leo Pharma Canada, Thornhill, ON, Canada
⁶LEO Pharma A/S, Ballerup, France
⁷Taussig Cancer Institute, Cleveland Clinic Lerner College of Medicine, Cleveland Clinic, Cleveland, OH

Jasmeet Kaur, MD, MBBS¹, Anupam A Sule, MD, PhD, FACP^1*, Tracy Koehler^2*, Geetha Krishnamoorthy, MD, FACP^1* and Jennifer DeLongpre, MD^3*

¹Department of Internal Medicine, Saint Joseph Mercy Oakland Hospital, Pontiac, MI
²Saint Joseph Mercy Oakland Hospital, Pontiac
³Department of Internal Medicine, Mercy Health Muskegon, Muskegon, MI

Leonardo R. Brandao, MD¹, Igor Tartakovsky, MD^2*, Manuela Albisetti, MD^3*, Lisa Bomgaars, MD^4*, Elizabeth Chalmers, MD^5*, Lesley Mitchell, MD^6*, Matteo Luciani, MD^7*, Paola Saracco, MD^8*, Judy Felgenhauer, MD^9*, Olga Lvova, MD^10,11*, Monika Simetzberger, DI^12*, Zhichao Sun, PhD^13*, Ingrid Gergei, MD^2*, Martina Brueckmann, MD^2,14* and Jacqueline Halton, MD^15*

¹Paediatric Haemotology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada
²Therapeutic Area Cardiovascular Medicine, Boehringer Ingelheim International GmbH, Ingelheim, Germany
³Hematology Department, University Children’s Hospital, Zürich, Switzerland
⁴Department of Pediatrics, Texas Children’s Cancer Center, Baylor College of Medicine, Houston, TX
⁵Royal Hospital for Children, Glasgow, United Kingdom
⁶University of Alberta, Edmonton, Canada
⁷Pediatric Hematology/Oncology Department, Pediatric Hospital Bambino Gesù, Rome, Italy
⁸University Hospital, City of Health and Science of Turin, and Pediatric Hematology, Queen Margaret’s Children's Hospital, Turin, Italy
⁹Pediatric Hematology Oncology, Providence Sacred Heart Medical Center and Children's Hospital, Spokane, WA
¹⁰Ural Federal University, Yekaterinburg, Russian Federation
¹¹Children’s City Hospital #9, Yekaterinburg, Russian Federation
¹²Department of Clinical Development, Boehringer Ingelheim RCV GmbH & Co. KG, Vienna, Austria
¹³Biostatistics and Data Sciences, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT
¹⁴Faculty of Medicine Mannheim of the University of Heidelberg, Mannheim, Germany
¹⁵University of Ottawa, Children’s Hospital of Eastern Ontario, Ottawa, Canada

Lisa Baumann Kreuziger, MD^1,2, Mingen Feng, MS^2*, Abigail Bartosic, CCRP^3*, Pippa Simpson, PhD^2* and Tzu-Fei Wang, MD, MPH⁴

¹Versiti, Blood Research Institute, Milwaukee, WI
²Medical College of Wisconsin, Milwaukee, WI
³The Ohio State University, Columbus, OH
⁴Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH

Daniel Röshammar, PhD^1*, Fenglei Huang, PhD^2*, Manuela Albisetti, MD^3*, Lisa Bomgaars, MD^4*, Elizabeth Chalmers, MD^5*, Matteo Luciani, MD^6*, Jacqueline Halton, MD^7*, Lesley Mitchell, MD^8*, David Joseph, PhD^2*, Igor Tartakovsky, MD^9*, Savion Gropper, MD^10*, Martina Brueckmann, MD^9,11* and Leonardo R. Brandao, MD¹²

¹Pharmetheus AB, Uppsala, Sweden
²Translational Medicine and Clinical Pharmacology, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, CT
³Hematology Department, University Children’s Hospital, Zürich, Switzerland
⁴Department of Pediatrics, Texas Children’s Cancer Center, Baylor College of Medicine, Houston, TX
⁵Royal Hospital for Children, Glasgow, United Kingdom
⁶Pediatric Hematology/Oncology Department, Pediatric Hospital Bambino Gesù, Rome, Italy
⁷University of Ottawa, Children’s Hospital of Eastern Ontario, Ottawa, Canada
⁸University of Alberta, Edmonton, Canada
⁹Therapeutic Area Cardiovascular Medicine, Boehringer Ingelheim International GmbH, Ingelheim, Germany
¹⁰Therapeutic Area Inflammation Medicine, Boehringer Ingelheim International GmbH, Ingelheim, Germany
¹¹Faculty of Medicine Mannheim of the University of Heidelberg, Mannheim, Germany
¹²Paediatric Haemotology/Oncology, The Hospital for Sick Children, Toronto, ON, Canada

Juan Cardenas, PhD^1*, Jayaprakash Kotha, PhD, MBBS^1*, Genmin Lu^2*, Pamela B. Conley, PhD^3*, Matthieu Bourdin^4*, Tristan Herve^5* and Lisa K. Jennings, PhD¹

¹CirQuest Labs, LLC as MLM Medical Labs, LLC, Memphis, TN
²Portola Pharmaceuticals, Inc., a wholly owned subsidiary of Alexion Pharmaceuticals, Inc., Burlingame, CA
³Portola Pharmaceuticals, Inc., a wholly owned subsidiary of Alexion Pharmaceuticals, Inc., South San Francisco, CA
⁴Diagnostica Stago, Gennevilliers, France
⁵Diagnostica Stago, Asnieres sur Seine Cedex, France

Lantarima Bhoopat, MD^1*, Anastasia Martynova, MD², April Choi, MD^3*, Pattharawin Pattharanitima, MD^4*, Semi Han, MD^5*, Senxi Du^6*, Ibrahim Syed^7*, Catherine Chan, PharmD^8*, Caitlin O'Neill, MD⁹, Esther Oh, PharmD^10* and Casey L. O'Connell, MD¹¹

¹Hematology, Department of Internal Medicine, Thammasat University, Patumthani, Thailand
²University of Southern California, Jane Anne Nohl Division of Hematology, Los Angeles, CA
³Depatment of Internal Medicine, University of Southern California, Los Angeles, CA
⁴Nephrology, Department of Internal Medicine, Thammasat University, Patumthani, Thailand
⁵Department of Internal Medicine, University of Southern California, Los Angeles, CA
⁶University of Southern California, Keck School of Medicine, Los Angeles, CA
⁷Jane Anne Nohl Division of Hematology, Keck School of Medicine of the University of Southern California, Los Angeles, CA
⁸LAC+USC Medical Center, Los Angeles, CA
⁹University of Southern California, Jane Anne Nohl Division of Hematology, Keck School of Medicine, Los Angeles, CA
¹⁰LAC+USC Medical Center, Los Angles, CA
¹¹Jane Anne Nohl Division of Hematology, Keck School of Medicine, University of Southern California, Los Angeles, CA

Fakiha Siddiqui^1*, Debra Hoppensteadt, PhD^1*, Jeanine Walenga, PhD², Walter Jeske, PhD^2*, Alfonso J Tafur, MD, MS^3*, Eduardo Ramacciotti, PhD, MD^1* and Jawed Fareed, PhD¹

¹Pathology, Loyola University Medical Center, Maywood, IL
²Thoracic and Cardiovascular Surgery, Loyola University Medical Center, Maywood, IL
³Cardiology - Vascular Medicine., NorthShore University HealthSystem, Evanston, IL

Rich Kodama, MD^1*, Amardeep Kalsi, MD^1*, Angelica Singh, MD^2*, Nivetha Vishnuvardhan, MD², Neil Nimkar, MD¹, Sonal Paul, MD², Soeb Usta, MD^1*, Farah Ashraf, MD^1*, Anita Mazloom, MD¹, Abeer Ashfaq, MD^1*, Nisha Patel, MD^1*, Chathula Kumarasinghe, MD^1*, Uqba Khan, MD^1*, Peter Gregos, MD¹, Jeremy Weingarten, MD^1* and Eshan Patel, MD²

¹New York-Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY
²NewYork-Presbyterian Brooklyn Methodist Hospital, Brooklyn, NY

Camille Simard, MD^1*, Maral Koolian, MD, MSc, FRCPC^2*, Diana Escobar, MD^3*, Mark Blostein, MD FRCPC^4*, Jed Lipes, MD, FRCPC^5*, Adelina Teona Avram, MD^1*, Ryan Kerzner, B Pharm, MSc^6*, Helen Mantzanis, B Pharm, MSc^6*, Mateo Porres Aguilar, MD^1* and Vicky Tagalakis, MD, FRCPC⁷

¹McGill University, Montreal, QC, Canada
²General Internal Medicine, Jewish General Hospital, McGill University, Montreal, QC, Canada
³McGill University, Monteal, QC, Canada
⁴Division of Hematology, Jewish General Hospital, McGill University, Montreal, QC, Canada
⁵Critical Care Medicine, Jewish General Hospital, McGill University, Montreal, QC, Canada
⁶Department of Pharmacy, Jewish General Hospital, Montreal, QC, Canada
⁷Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, Jewish General Hospital, McGill University, Montreal, QC, Canada