Mikkael A. Sekeres¹, Justin M. Watts, MD², Atanas Radinoff^3*, Montserrat Arnan Sangerman, MD, PhD^4*, Marco Cerrano^5*, Patricia Font Lopez^6*, Joshua F. Zeidner, MD⁷, Maria Diez-Campelo, PhD, MD^8*, Carlos Graux^9*, Jane L. Liesveld, MD¹⁰, Dominik Selleslag, MD¹¹, Nikolay Tzvetkov, MD^12*, Robert J. Fram^13*, Dan Zhao^13*, Sharon Friedlander^13*, Kevin Galinsky^13*, Douglas V. Faller^13* and Ades Lionel^14*

¹Leukemia Program, Cleveland Clinic, Cleveland, OH
²University of Miami Sylvester Comprehensive Cancer Center, Miami, FL
³University Hospital Sveti Ivan Rislki, Sofia, Bulgaria
⁴Institut Català d'Oncologia-Institut d'Investigació Biomèdica de Bellvitge (IDIBELL), Hospitalet, Barcelona, Spain
⁵Department of Molecular Biotechnology and Health Sciences, Division of Hematology, University of Turin, Turin, Italy
⁶Hospital General Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), Madrid, Spain
⁷University of North Carolina, Lineberger Comprehensive Cancer Center, Chapel Hill, NC
⁸University Hospital of Salamanca, IBSAL Institute for Biomedical Research of Salamanca, Salamanca, Spain
⁹Université Catholique de Louvain, Centre Hospitalier Universitaire, Namur, Yvoir, Belgium
¹⁰The James P Wilmot Cancer Institute, University of Rochester, Rochester, NY
¹¹AZ Sint Jan Brugge-Oostende, Brugge, Belgium
¹²MHAT Dr. Georgi Stranski, Clinic of Haematology, Pleven, Bulgaria
¹³Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, MA
¹⁴Hôpital Saint-Louis Hématologie Clinique, Paris, France

Raphael Itzykson, MD, PhD¹, Valeria Santini^2*, Cendrine Chaffaut^3*, Ades Lionel^3*, Sylvain Thepot, MD^4*, Aristoteles Giagounidis⁵, Margot Morabito^6*, Nathalie Droin^7*, Michael Luebbert⁸, Rosa Sapena^9*, Stanislas Nimubona, MD^10*, Jean E. Goasguen, MD, PhD^11*, Eric Wattel, MD, PhD^12*, Gina Zini, MD, PhD^13*, Jose Miguel Torregrosa Diaz^14*, Ulrich Germing^15*, Anna Maria Pelizzari^16*, Sophie Park, MD, PhD^17*, Nadja Jaekel^18*, Georgia Metzgeroth^19*, Francesco Onida, MD²⁰, Robert Navarro^21*, Andrea Patriarca, MD^22*, Aspasia Stamatoulas Bastard, MD^23*, Martin Puttrich^24*, Sandra Mossuto^25*, Eric Solary, MD, PhD⁶, Silke Gloaguen, Msc^26*, Sylvie Chevret, MD, PhD^27*, Fatiha Chermat^28*, Uwe Platzbecker, MD²⁹ and Pierre Fenaux, MD, PhD³⁰

¹Hematology Department, Saint-Louis Hospital AP-HP Paris France, Paris, France
²MDS Unit, Azienda Ospedaliero Universitaria Careggi, University of Florence, Florence, FI, Italy
³Hopital Saint-Louis, Paris, France
⁴Service des Maladies du Sang, CHU Angers, Angers, France
⁵Marien Hospital Düsseldorf, Düsseldorf, Germany
⁶INSERM U1170, Université Paris-Sud, Gustave Roussy Cancer Center, Villejuif, France
⁷Gustave Roussy, UMR1170 - Universite Paris Sud, Villejuif, France
⁸Department of Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Freiburg, Germany
⁹Groupe Francophone des Myélodysplasies, Paris, France
¹⁰CHU rennes, Rennes, France
¹¹Université de Rennes, Rennes, FRA
¹²Centre Hospitalier Lyon Sud, PIERRE BENITE, FRA
¹³Catholic University of the Sacred Heart Policlinico Gemelli, Rome, ITA
¹⁴Department of Hematology and Oncology, CHU de Poitiers, Poitiers, FRA
¹⁵Department of Hematology, Oncology and Clinical Immunology, Heinrich-Heine-University, Faculty of Medicine, Düsseldorf, Germany
¹⁶Department of Hematology, ASST Spedali Civili di Brescia, Brescia, Italy
¹⁷Department of Hematology, CHU Grenoble, Grenoble Cedex 9, France
¹⁸University Hospital Halle (Saale), Halle, Germany
¹⁹Department of Hematology and Oncology, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
²⁰BMT Center - Hematology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - University of Milan, Milano, Italy
²¹Department of Hematology and Oncology, CHU Montpellier, Hopital Saint-Eloi, Montpellier, France
²²Division of Hematology, Department of Translational Medicine,, University of Eastern Piedmont, Novara, ITA
²³Henri Becquerel Center, Rouen, France
²⁴GMIHO - innovation in hematology and medical oncology, Dresden, Germany
²⁵FISM, Firenze, Italy
²⁶The European Myelodysplastic Syndromes Cooperative Group (EMSCO), Leipzig, Germany
²⁷Division of Biostatistics, Saint-Louis Hospital, GH APHP Nord Université de Paris, Paris, France
²⁸Service d'Hématologie Séniors, Hôpital Saint-Louis, Paris, France
²⁹Hematology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany
³⁰Hôpital Saint-Louis, Paris, France

Nathan Radakovich, BA¹, David A. Sallman, MD², Rena J. Buckstein, MD, FRCPC³, Andrew M. Brunner, MD⁴, Sudipto Mukherjee, MD, PhD, MPH⁵, Rami Komrokji, MD², Najla Al Ali, M.Sc^6*, Jacob Shreve, BS, MD, MS⁷, Yazan Rouphail^8*, Cassandra M Kerr, MS^9*, Yihong Guan, PhD^9*, Teodora Kuzmanovic, BA^10*, Metis Hasipek, PhD^10*, Babal K. Jha, PhD^9*, Jaroslaw P. Maciejewski, MD, PhD¹⁰, Mikkael A. Sekeres, MD, MS¹¹ and Aziz Nazha, MD¹²

¹Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Bellingham, WA
²H. Lee Moffitt Cancer Center, Tampa, FL
³Sunnybrook Odette Cancer Center, Toronto, ON, Canada
⁴Dana-Farber Cancer Institute, Boston, MA
⁵Leukemia Program, Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
⁶H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁷Cleveland Clinic, Cleveland, OH
⁸Ohio State University, Rocky River, OH
⁹Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH
¹⁰Department of Translational Hematology and Oncology Research, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
¹¹Leukemia Program, Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
¹²Leukemia Program, Department of Hematology and Medical Oncology, Taussig Cancer Institute, Quantitative Health Sciences, Avon Lake, OH

Jacqueline S. Garcia, MD¹, Andrew H. Wei², Uma Borate³, Chun Yew Fong, MBBS, PhD, FRACP, FRCPA⁴, Maria R. Baer, M.D.⁵, Florian Nolte, MD^6*, Joseph G. Jurcic, MD⁷, Meagan A. Jacoby, MD⁸, Wan-Jen Hong, MD⁹, Uwe Platzbecker, MD¹⁰, Olatoyosi Odenike, MD¹¹, Ilona Cunningham, MBBS, FRACP, FRCPA¹², Ying Zhou, PhD^13*, Bo Tong, PhD^13*, Leah Hogdal, PhD^13*, Rajesh Kamalakar, MS^13*, Jessica E. Hutti, PhD^13*, Steve Kye, MD, MPH¹³ and Guillermo Garcia-Manero, MD¹⁴

¹Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
²Department of Haematology, Alfred Hospital and Monash University, Melbourne, Australia
³Division of Hematology and Medical Oncology, Knight Cancer Institute, Oregon Health and Science University, Portland, OR
⁴Olivia Newton John Cancer Research Institute, Austin Health, Melbourne, VIC, Australia
⁵Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD
⁶Department of Hematology and Oncology, University Hospital Mannheim, Mannheim, Germany
⁷Myelodysplastic Syndromes Center, Columbia University Medical Center, Columbia University, New York, NY
⁸Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine, St. Louis, MO
⁹Genentech, Inc., South San Francisco, CA
¹⁰Hematology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany
¹¹University of Chicago Medicine and Comprehensive Cancer Center, Chicago, IL
¹²Haematology Department, Concord Repatriation General Hospital, University of Sydney, Sydney, Australia
¹³AbbVie Inc., North Chicago, IL
¹⁴Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Andrew M. Brunner, MD¹, Jordi Esteve, MD, PhD², Kimmo Porkka³, Steve Knapper⁴, Norbert Vey, MD⁵, Sebastian Scholl^6*, Guillermo Garcia-Manero, MD⁷, Martin Wermke^8*, Jeroen Janssen^9*, Elie Traer¹⁰, Sun Loo^11*, Rupa Narayan^1*, Natalia Tovar^12*, Mika Kontro^3*, Oliver Ottmann⁴, Purushotham Naidu^13*, Sema Kurtulus^14*, Jessica Makofske^14*, Serena Liao^14*, Anisa Mohammed^13*, Catherine A. Sabatos-Peyton^14*, Mikael L. Rinne^14*, Uma Borate¹⁰ and Andrew H. Wei, MBBS, PhD¹⁵

¹Massachusetts General Hospital, Boston, MA
²Hematology Department, Hospital Clínic de Barcelona, Barcelona, Spain
³Helsinki University Hospital Comprehensive Cancer Center, Department of Hematology, Helsinki, Finland
⁴Cardiff University, Cardiff, United Kingdom
⁵Institut Paoli-Calmettes, Marseille, France
⁶University Hospital Jena, Jena, Germany
⁷MD Anderson Cancer Center, Houston, TX
⁸University Hospital Dresden, Dresden, Germany
⁹Amsterdam University Medical Centers, VU University Medical Center, Amsterdam, Netherlands
¹⁰Oregon Health & Science University, Portland, OR
¹¹The Alfred Hospital, Melbourne, VIC, Australia
¹²Hospital Clínic, Barcelona, Spain
¹³Novartis Pharmaceuticals Corporation, East Hanover, NJ
¹⁴Novartis Institutes for BioMedical Research, Cambridge, MA
¹⁵The Alfred Hospital and Monash University, Melbourne, VIC, Australia

Uwe Platzbecker, MD¹, Pierre Fenaux, MD, PhD², David P. Steensma, MD³, Koen Van Eygen, MD^4*, Azra Raza, MD⁵, Ulrich Germing^6*, Patricia Font, MD^7*, Maria Diez-Campelo, PhD, MD^8*, Sylvain Thepot, MD^9*, Edo Vellenga, MD, PhD¹⁰, Mrinal M. Patnaik, MD, MBBS¹¹, Jun Ho Jang, MD, PhD¹², Helen Varsos, MS, RPh^13*, Esther Rose, MD^13*, Jacqueline Bussolari, PhD¹³, Fei Huang, PhD^14*, Souria Dougherty, BS, MBA^14*, Libo Sun, PhD^14*, Ying Wan, PhD^14*, Aleksandra Rizo, MD, PhD¹⁴ and Valeria Santini¹⁵

¹Hematology and Cellular Therapy, University Hospital Leipzig, Leipzig, Germany
²Hôpital Saint-Louis, Université Paris Diderot, Paris, France
³Dana-Farber Cancer Institute, Boston, MA
⁴Algemeen Ziekenhuis Groeninge, Kortrijk, Belgium
⁵Columbia University Medical Center, New York, NY
⁶Department of Hematology, Oncology and Clinical Immunology, Heinrich-Heine-University, Faculty of Medicine, Düsseldorf, Germany
⁷Department of Hematology, Hospital General Universitario Gregorio Marañon, Madrid, Spain
⁸Grupo Español de Síndromes Mielodisplásicos (GESMD), salamanca, salamanca, Spain
⁹Service des Maladies du Sang, CHU Angers, Angers, France
¹⁰Department of Hematology, University Medical Center Groningen, Groningen, Netherlands
¹¹Division of Hematology, Mayo Clinic, Rochester, MN
¹²Department of Hematology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of (South)
¹³Janssen Research & Development, LLC, Raritan, NJ
¹⁴Geron Corporation, Parsippany, NJ
¹⁵MDS Unit- Hematology, AOU Careggi-University of Florence, Firenze, Fi, Italy