-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

632.O1.6 632: Chronic Myeloid Leukemia: Therapy: CML: New and Beyond

Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Biological, SARS-CoV-2/COVID-19, Coronaviruses, Adult, Non-Biological, Diseases, CML, Therapies, Adverse Events, white blood cells, Biological Processes, Technology and Procedures, Cell Lineage, Study Population, Clinically relevant, Myeloid Malignancies, hematopoiesis, pharmacology, flow cytometry, TKI
Monday, December 7, 2020: 11:30 AM-1:00 PM
Moderators:
Franck E Nicolini, MD, PhD, Centre Hospitalier Lyon Sud and Jane Apperley, FRCP, FRCPath, MB , Hammersmith Hospital, Imperial College
Disclosures:
Nicolini: Sun Pharma Ltd: Consultancy; Incyte Biosciences: Research Funding, Speakers Bureau; Novartis: Research Funding, Speakers Bureau. Apperley: Incyte: Honoraria, Research Funding, Speakers Bureau; Novartis: Honoraria, Speakers Bureau; Pfizer: Honoraria, Research Funding, Speakers Bureau; Bristol Myers Squibb: Honoraria, Speakers Bureau.
11:30 AM

Hagop M. Kantarjian, MD1, Michael W. Deininger, MD, PhD2, Elisabetta Abruzzese, MD 3, Jane Apperley, FRCP, FRCPath, MB 4, Jorge E. Cortes, MD5, Charles Chuah, MD6, Daniel J. DeAngelo, MD, PhD7, John F. DiPersio, MD8, Andreas Hochhaus, MD9, Jeffrey H. Lipton, MD, PhD10, Franck E Nicolini, MD, PhD11, Javier Pinilla Ibarz, MD, PhD12, Delphine Rea, MD, PhD13,14, Gianantonio Rosti, MD15*, Philippe Rousselot, MD PhD16*, Neil P Shah, MD, PhD17*, Moshe Talpaz, MD18, Shouryadeep Srivastava, MBBS, PhD19*, Vickie Lu, PhD20* and Michael J. Mauro, MD21

1Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
2Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
3S. Eugenio Hospital, Tor Vergata University, Rome, Italy
4Centre for Haematology, Imperial College London, London, United Kingdom
5Georgia Cancer Center Augusta University, Augusta, GA
6Singapore General Hospital, Duke-NUS Medical School, Singapore, Singapore
7Department of Medical Oncology, Dana-Farber Cancer Inst., Boston, MA
8Washington University School of Medicine, Saint Louis, MO
9Jena University Hospital, Jena, Germany
10Princess Margaret Cancer Centre, University of Toronto, Toronto, ON, Canada
11Hématologie Clinique, Centre Léon Bérard, Lyon, France
12H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
13Hôpital Saint Louis, Paris, France
14Hôpital Saint-Louis, Paris, France
15University of Bologna, Bologna, Italy
16Hospital Mignot University de Versailles Saint-Quentin-en-Yvelines, Paris, France
17University of California San Francisco, San Francisco, CA
18Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI
19Millennium Pharmaceuticals, Inc., Cambridge, MA, USA, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, MA
20Millennium Pharmaceuticals, Inc., a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, Cambridge, MA
21Myeloproliferative Neoplasms Program, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY

11:45 AM

Monica Bocchia1*, Anna Sicuranza, PhD2*, Paola Pacelli2,3*, Alessandra Iurlo, MD, PhD4*, Elisabetta Abruzzese, MD 5, Sara Galimberti, MD, PhD6*, Patrizia Pregno7*, Giovanni Caocci, MD8,9, Isabella Capodanno, MD10*, Monica Crugnola, MD11*, Antonella Gozzini, MD12*, Claudio Fozza, MD13*, Mario Annunziata, MD14*, Sabina Russo15*, Anna Marina Liberati16*, Olga Mulas17*, Daniele Cattaneo18*, Adele Santoni19*, Vincenzo Sammartano19*, Federico Caroni20* and Donatella Raspadori2*

1Hematology, University of Siena, Siena, Italy
2Hematology, University of Siena, Azienda Ospedaliera Universitaria Senese, Siena, Italy
3Department of Medical Biotechnologies, University of Siena, Siena, Italy
4Hematology Division, Foundation IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milano, Italy
5Department of Hematology S. Eugenio Hospital, Rome, Italy, Roma, Italy
6Department of Clinical and Experimental Medicine, Section of Hematology, University of Pisa, Pisa, Italy
7AZ OSP CITTA' DELLA SALUTE E SCIENZA TORINO, University of Torino, TORINO, Italy
8Ematologia-Centro Trapianti Midollo Osseo, Ospedale Businco, Dipartimento di Scienze mediche e Sanità Pubblica, Università di Cagliari, Cagliari, Italy
9Hematology Unit, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, ITA
10Hematology Unit, Azienda Unità Sanitaria Locale - IRCCS, Reggio Emilia, Italy
11Division of Hematology, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy
12Hematology Unit, AOU Careggi, University of Florence, Florence, ITA
13Department of Clinical and Experimental Medicine, University of Sassari, Sassari, Italy
14Hematology Unit, Cardarelli Hospital, Naples, Italy
15Dipartimento di Medicina Interna, AOU Policlinico di Messina, Messina, Italy
16S.C. Oncoematologia, Università degli Studi di Perugia, A.O. Santa Maria, Terni, Italy
17Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy
18FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO, MILANO, ITA
19Hematology Unit, Azienda Ospedaliera Universitaria Senese, University of Siena, Siena, ITA
20Hematology Unit, University of Siena and Azienda Ospedaliera Universitaria Senese, Siena, Italy

12:00 PM

Delphine Rea, MD, PhD1, Michael J. Mauro, MD2, Jorge E. Cortes, MD3, Qian Jiang, MD4, Katia B Pagnano, MD, PhD5, Matilda Ongondi, MD6*, Chung Hoow Kok, BSc, PhD7*, Nicola Evans8*, Timothy P. Hughes, MD, MBBS, FRACP, FRCPA9 and International CML Foundation10*

1Université de Paris, Hematology department, Saint-Louis hospital, APHP, Paris, France
2Myeloproliferative Neoplasms Program, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
3Georgia Cancer Center Augusta University, Augusta, GA
4Peking University People’s Hospital, Beijing, China
5University of Campinas, Campinas, Brazil
6Kenyatta National Hospital, Nairobi, KEN
7Precision Medicine Theme, South Australian Health and Medical Research Institute, Adelaide, Australia
8International CML Foundation, Adelaide, SA, Australia
9South Australian Health and Medical Research Institute SAHMRI, Adelaide, SA, Australia
10iCMLf, Bexhill-On-Sea, United Kingdom

12:15 PM

Jorge E. Cortes, MD1, Timothy P. Hughes, MD, MBBS, FRACP, FRCPA2, Michael J. Mauro, MD3, Andreas Hochhaus, MD4, Delphine Rea, MD, PhD5, Yeow Tee Goh, MBBS6, Jeroen Janssen7*, Juan Luis Steegmann8, Michael C. Heinrich, MD9*, Moshe Talpaz, MD10, Gabriel Etienne, MD, PhD11*, Massimo Breccia, MD12*, Michael W. Deininger, MD, PhD13, Philipp D le Coutre, MD14, Fabian Lang, MD15*, Paola Aimone, MD16*, Fotis Polydoros16*, Silvia Cacciatore16*, Laura Stenson17* and Dong-Wook Kim, MD18

1Georgia Cancer Center Augusta University, Augusta, GA
2South Australian Health and Medical Research Institute SAHMRI, Adelaide, SA, Australia
3Myeloproliferative Neoplasms Program, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
4Klinik für Innere Medizin II, Jena, Germany
5Hopital Saint Louis, Paris, France
6Department of Hematology, Singapore General Hospital, Singapore, Singapore
7VU University Medical Center, Amsterdam, NLD
8Hospital de La Princesa, Madrid, Spain
9Portland VA Health Care System, Portland, OR
10University of Michigan Comprehensive Cancer Center, Ann Arbor, MI
11Hematology Department, Institut Bergonié, Bordeaux, France
12Department of Translational and Precision Medicine, Sapienza University, Rome, Italy
13Huntsman Cancer Institute, The University of Utah, Salt Lake City, UT
14Charité – Universitätsmedizin Berlin, Berlin, Berlin, Germany
15Department of Medicine II, Hematology/Oncology, Goethe University, Frankfurt, Germany
16Novartis Pharma AG, Basel, Switzerland
17Novartis Ireland Limited, Dublin, Ireland
18Seoul St. Mary's Hospital The Catholic University of Korea, Seoul, Korea, Republic of (South)

12:30 PM

Qian Jiang, MD1, Xiaojun Huang, MD1, Zi Chen, MD2*, Qian Niu, MD2*, Dayu Shi1*, Zongru Li1*, Yue Hou1*, Yu Hu, MD3*, Weiming Li, PhD3*, Xiaoli Liu4*, Na Xu4*, Yongping Song, MD5*, Yanli Zhang5*, Li Meng, MD, PhD6*, Zhenya Hong, MD, PhD6*, Bingcheng Liu7*, Shan Zeng2*, Lichuang Men2*, Yan Li, MD8*, Suning Chen9*, Mengxing Xue, PhD10*, Huanling Zhu, MD11*, He Li11*, Xin Du12*, Jin Lou, MD12*, Xiaohan Zhang12*, Yang Liang, MD13, Yujun Dai, MD, PhD13*, Ming Lu, PhD14*, Hengbang Wang2*, Jiao JI, PhD, MD2*, Changai Yue2*, Dajun Yang, MD, PhD15,16* and Yifan Zhai, MD, PhD2,14*

1Peking University Institute of Hematology, Peking University People's Hospital, Beijing, China
2Guangzhou Healthquest Pharma Co. Ltd., Guangzhou, China
3Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
4Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China
5Department of Hematology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China
6Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
7Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
8Institute of Hematology and Blood Diseases Hospital, National Clinical Research Center for Blood Diseases, Tianjin, China
9National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China
10Department of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China
11Department of Hematology, West China Hospital of Sichuan University, Chengdu, China
12Division of Hematology, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, China
13Department of Hematologic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, China
14Ascentage Pharma Group Inc., Rockville, MD
15Ascentage Pharma (SuZhou) Co., Ltd, Suzhou, China
16Collaborative Innovation Center for Cancer Medicine, State Key Laboratory of Oncology in South China, Guangzhou, China

12:45 PM

Jorge E. Cortes, MD1, Tapan Saikia, MD2, Dong-Wook Kim, MD3,4, Yesid Alvarado, MD5, Franck E Nicolini, MD, PhD6, Navin Khattry, MD, DM7*, Krishnakumar Rathnam, MD, DM8*, Jane Apperley, FRCP, FRCPath, MB 9, Michael W. Deininger, MD, PhD10, Hugues de Lavallade, MD, PhD11*, Aude Charbonnier, MD, PhD12*, Nikki Granacher, MD13*, Carlo Gambacorti-Passerini, MD14, Alessandro Lucchesi, MD15*, Michael J. Mauro, MD16, Gregor Verhoef, MD, PhD17*, Peter Vandenberghe, MD18, Andrew R. Whiteley, MD19, Shashikant Apte, MD, FRCPA20, Siu-Long Yao, MD21, Mudgal Kothekar, MD22*, Jayasree Sreenivasan, MSc22*, Bimba HV, MD22* and Geetanjali Chimote, MD, PhD22*

1Georgia Cancer Center Augusta University, Augusta, GA
2Prince Aly Khan Hospital, Mumbai, India
3Seoul St. Mary's Hospital The Catholic University of Korea, Seoul, Korea, Republic of (South)
4Department of Hematology, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, Korea, Republic of (South)
5Department of Leukemia, MD Anderson Cancer Center, Houston, TX
6Hematology department & ISERM U590, Centre Hospitalier Lyon Sud, LYON Cedex 03, France
7BMT unit, Department of Medical oncology, ACTREC., Tata Memorial Centre, Navi Mumbai, India
8Lake Area,Melur Main Rd, Meenakshi Mission Hospital and Research Centre, Tamil Nadu, India
9Centre for Haematology, Department of Medicine, Hammersmith Hospital, Imperial College, London, United Kingdom
10Division of Hematology and Hematologic Malignancies, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
11Department of Haematological Medicine, Kings College Hospital, NHS Foundation Trust, London, United Kingdom
12Onco-Hematology Department, Paoli-Calmette Cancer Institute, Marseille, France
13Ziekenhuis Netwerk Antwerpen, Antwerp, Belgium
14Dept of Medicine and Surgery, University of Milano Bicocca, Monza, MB, Italy
15Hematology Unit,, Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola (FC), FC, Italy
16Myeloproliferative Neoplasms Program, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
17Department of Hematology, University Hospitals Leuven, Leuven, Belgium
18Center for Human Genetics, University of Leuven Center for Human Genetics, Leuven, Belgium
19Baylor University Medical Center, Dallas, TX
20Department of Haematology, Sahyadri Specialty Hospitals, Pune, India
21Sun Pharmaceutical Industries, Inc., Princeton, NJ
22Clinical Research Department, Sun Pharma Advanced Research Company, Mumbai, Maharashtra, India

*signifies non-member of ASH