-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

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Ticketed Session denotes that this is a ticketed session.

501.O1.6 501. Hematopoietic Stem and Progenitor Biology: New Insights into the Molecular Regulation of Hematopoietic Stem Cells

Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
HSCs, Diseases, cell division, cell regulation, Bone Marrow Failure, cellular interactions, Biological Processes, immunodeficiency, cell expansion, Technology and Procedures, Immune Disorders, Cell Lineage, epigenetics, erythropoiesis, Neutropenia, hematopoiesis, metabolomics, microenvironment, molecular interactions, pathways
Saturday, December 5, 2020: 2:00 PM-3:30 PM
Moderators:
Sergei Doulatov, PhD, University of Washington School of Medicine and Moonjung Jung, MD, The Rockefeller University
Disclosures:
No relevant conflicts of interest to declare.
2:00 PM

Abhishek K Singh, PhD1, Ashley M Wellendorf, B.S.2*, Breanna Bohan, B.S.3*, Daniel Gonzalez-Nieto, PhD4*, Luis C Barrio, MD, PhD5*, Ashwini S. Hinge, PhD2*, Marie-Dominique Filippi, PhD6 and Jose A. Cancelas, MD7

1Cincinnati Children's Hospital Medical Center & Hoxworth Blood Center, University of Cincinnati, Cincinnati, OH
2Cincinnati Children's Hospital Medical Center, Cincinnati, OH
3University of Cincinnati, Cincinnati, OH
4Universidad Politecnica de Madrid, Madrid, Spain
5Hospital Ramon y Cajal, Madrid, Spain
6Stem Cell Program, Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital, Cincinnati, OH
7Hoxworth Blood Center, Univ. of Cincinnati, Cincinnati, OH

2:15 PM

Wenqing Wang, PhD1, Andrew Devilbiss, PhD2*, Thomas Mathews, PhD2*, Martin Arreola3*, Misty Martin4*, Zhiyu Zhao, DPhil5*, Avni Awani, PhD3*, Daniel P. Dever, PhD6*, Matthew H. Porteus, MD, PhD7, Sean Morrison, PhD2 and Katja G Weinacht, MD, PhD8*

1Department of Pediatrics, Division of Stem Cell Transplantation and Regenerative Medicine, Stanford University, Stanford, CA
2University of Texas Southwestern Medical Center, Dallas, TX
3Stanford University School of Medicine, Stanford, CA
4University of Texas South Western, Dallas, TX
5Children's Research Institute and the Department of Pediatrics, UT Southwestern Medical Center, Dallas, TX
6Department of Pediatrics, Stanford University School of Medicine, Stanford, CA
7Department of Pediatrics, Stanford School of Medicine, Stanford, CA
8Department of Pediatrics, Division of Stem Cell Transplantation and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA

2:30 PM

Laura Garcia Prat, PhD, BSc, MSc1,2, Kerstin B Kaufmann, PhD1, Florin Schneiter3*, Veronique Voisin, PhD4*, Alex Murison1*, Michelle Chan-Seng-Yue1,5*, Olga I. Gan, PhD1,2*, Jessica L. McLeod1*, Michelle Shoong1*, Kristele Pan1*, Kinam Gupta6*, Shin-Ichiro Takayanagi, PhD1*, Elvin Wagenblast, PhD7, Weijia Wang3*, Timm Schroeder, PhD3*, Stephanie Zhi-Juan Xie, PhD1,2 and John E. Dick, PhD, FRS1,2

1Princess Margaret Cancer Centre, University Health Network (UHN), Toronto, ON, Canada
2Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
3Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland
4Terrence Donnelly Centre for Cellular and Biomedical Research, University of Toronto, Toronto, ON, Canada
5PanCuRx Translational Research Initiative, Ontario Institute for Cancer Research, Toronto, Canada
6German Cancer Research Center, DKFZ, Heidelberg, Germany
7Princess Margaret Cancer Centre, University Health Network (UHN), East York, ON, Canada

2:45 PM

Fengjiao Wang1*, Jiahuan He2*, Yanni Ma2*, Sha Hao3*, Siqi Liu2*, Ai Gao3*, Hui Cheng3*, Jia Yu2* and Tao Cheng4

1State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, 288 Nanjing Road, Tianjin, China, China
2Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS), School of Basic Medicine Peking Union Medical College, Beijing, China
3State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
4State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China

3:00 PM

Masatoshi Sakurai, MD, PhD1, Shinichiro Okamoto, MD, PhD1 and Satoshi Yamazaki, PhD2,3*

1Division of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
2Laboratory of Stem Cell Therapy, Faculty of Medicine University of Tsukuba, Ibaraki, Japan
3Division of Stem Cell Biology, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

3:15 PM

Stephanie A Luff, PhD1,2, J Philip Creamer IV, BA, BS3*, Carissa Dege, PhD4, Rebecca Scarfò5*, Samantha Morris, PhD6*, Andrea Ditadi, PhD5* and Christopher M. Sturgeon, PhD1,2

1Icahn School of Medicine at Mount Sinai, New York, NY
2Department of Internal Medicine, Division of Hematology, Washington University School of Medicine, St. Louis, MO
3Department of Internal Medicine, Division of Hematology, Washington University School of Medicine, Saint Louis, MO
4Department of Medicine, Division of Hematology, Washington University School of Medicine, St. Louis, MO
5San Raffaele Telethon Institute for Gene Therapy, IRCCS San Raffaele Scientific Institute, Milan, Italy
6Developmental Biology, Washington University, St. Louis, MO

*signifies non-member of ASH