Caleb K. Stein, MS^1*, Faith E Davies, MD¹, Christoph Heuck, MD¹, Niels Weinhold, PhD^1*, Shweta S. Chavan, PhD^1*, Brian A Walker, PhD², Sharmilan Thanendrarajan, MD¹, Joshua Epstein, DSc¹, Shmuel Yaccoby, PhD¹, Maurizio Zangari, MD¹, Frits van Rhee, MD, PhD¹, Martin F Kaiser, MD^3*, Graham H Jackson, MD, PhD⁴, Pieter Sonneveld, MD, PhD⁵, Hartmut Goldschmidt, MD⁶, Peter Leif Bergsagel, MD⁷, Bart Barlogie, MD, PhD¹ and Gareth J Morgan, MD PhD¹

¹Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, AR
²Centre for Myeloma Research, Division of Molecular Pathology, The Institute of Cancer Research, London, United Kingdom
³Division of Molecular Pathology, The Institute of Cancer Research, London, United Kingdom
⁴Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, United Kingdom
⁵Department of Hematology, Erasmus MC, Rotterdam, Netherlands
⁶Internal Medicine V, University Clinic Heidelberg, Heidelberg, Germany
⁷Division of Hematology and Oncology, Mayo Clinic, Scottsdale, AZ

Monique C. Minnema, MD, PhD¹, Sanne de Haart, MD^2*, Tuna Mutis, MD, PhD^2*, Marco Koudijs, PhD^3*, Marja van Blokland^4*, Henk Lokhorst, MD, PhD¹, Roel de Weger, MD, PhD^4* and Stefan Willems, MD, PhD^4*

¹Department of Hematology, Cancer Center, UMC Utrecht, Utrecht, Netherlands
²Department of Clinical Chemistry and Hematology, UMC Utrecht, Utrecht, Netherlands
³Department of Medical Genetics, UMC Utrecht, Utrecht, Netherlands
⁴Department of Molecular Pathology, UMC Utrecht, Utrecht, Netherlands

Paola Neri, MD, PhD¹, Ines Tagoug, PhD^1*, Justin Simms^1*, Ranjan Maity, PhD^1*, Jacquelyn Babich^1*, Victor Jimenez-Zepeda, MD^2*, Peter Duggan, MD², Fariborz Kolvear, PhD^3*, Jonathan J Keats, Ph.D.⁴, Leif Bergsagel, MD, PhD⁵ and Nizar J Bahlis, MD¹

¹University of Calgary, Southern Alberta Cancer Research Institute, Calgary, AB, Canada
²Department of Medical Oncology and Hematology, Tom Baker Cancer Center, Calgary, AB, Canada
³University of Calgary, Cancer Cytogenetics Laboratory, Calgary, AB, Canada
⁴Translational Genomics Research Institute, Phoenix, AZ
⁵Comprehensive Cancer Center, Mayo Clinic, Scottsdale, AZ

Moritz Binder, MD, MPH¹, S. Vincent Rajkumar, MD², Rhett P. Ketterling, MD^3*, Angela Dispenzieri, MD², Martha Q. Lacy, MD², Morie A. Gertz, MD², Francis Buadi, MD², Suzanne R. Hayman, MD², Yi L. Hwa, NP^2*, Steven R. Zeldenrust, MD, PhD², John A. Lust, MD, PhD², Stephen J. Russell, MD, PhD², Nelson Leung, MD^2,4, Prashant Kapoor, MD², Ronald S. Go, MD², Wilson I. Gonsalves, MD^2*, Robert A. Kyle, MD² and Shaji K. Kumar, MD²

¹Department of Internal Medicine, Mayo Clinic, Rochester, MN
²Division of Hematology, Mayo Clinic, Rochester, MN
³Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
⁴Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN

Maria Gkotzamanidou^1,2, Evangelos Terpos¹, Nikhil C. Munshi, MD³, Vassilis L. Souliotis^4* and Meletios A. Dimopoulos⁵

¹Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
²Department of Medical Oncology, Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
³LeBow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
⁴Institute of Biology, Medicinal Chemistry and Biotechnology, National Hellenic Research Foundation, Athens, Greece
⁵National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

Evangelos Terpos¹, Vassilis Koutoulidis^2*, Sofia Fontara^2*, Flora Zagouri^1*, Dimitrios Christoulas^3*, Dimitris Matsaridis^2*, Andreas Koureas^2*, Efstathios Kastritis, MD^1*, Meletios A. Dimopoulos⁴ and Lia A. Moulopoulos^2*

¹Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
²First Department of Radiology, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
³Department of Hematology, 251 General Air Force Hospital, Athens, Greece
⁴National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

Miki Furukawa, MD^1*, Hiroshi Ohkawara, MD, PhD^1*, Kazuhiko Ikeda, MD, PhD^1,2, Emi Ito, PhD^3*, Jun-ichi Imai, PhD^3*, Yuka Yanagisawa, PhD^3*, Reiko Honma, PhD^4*, Shinya Watanabe, MD, PhD^3*, Satoshi Waguri, MD, PhD^3*, Kazuei Ogawa, MD, PhD^1* and Yasuchika Takeishi, MD, PhD^1*

¹Department of Cardiology and Hematology, Fukushima Medical University, Fukushima, Japan
²Department of Blood Transfusion and Transplantation Immunology, Fukushima Medical University, Fukushima, Japan
³Translational Research Center, Fukushima Medical University, Fukushima, Japan
⁴NIPPON GENE, CO., LTD, Tokyo, Japan

*Luzalba Sanoja-Flores, M.Sc.^1,2*, *Bruno Paiva, PhD^3,4*, Juan A Flores-Montero, MD^1,2*, Noemi Puig, MD, PhD^5*, Leire Burgos^4*, Omar García, PhD^2*, Felipe Prosper, MD⁶, Juana Merino, MD PhD^3*, Maria Belen Vidriales, MD, PhD^5*, Maria-Victoria Mateos⁷, Ramon Garcia, MD^7*, Luis Palomera, MD PhD^8*, Rafael Rios^9*, María Consuelo Cañizo, MD, PhD^10*, Brian G M Durie¹¹, Jacques J.M. van Dongen¹², Jesus San Miguel, MD PhD^3,4* and Alberto Orfao, MD, PhD^1,2

¹Servicio General de Citometría (NUCLEUS) and Department of Medicine, University of Salamanca, Salamanca, Spain
²Cancer Research Center (IBMCC-CSIC/USAL-IBSAL), Salamanca, Spain
³Department of Hematology and Immunology, Clinica Universidad de Navarra, Pamplona, Spain
⁴Centro de Investigación Médica Aplicada, University of Navarra, Clínica Universidad de Navarra, Pamplona, Spain
⁵Department of Hematology, Hospital Universitario de Salamanca, Salamanca, Spain
⁶Clinica Universidad de Navarra, Pamplona, Spain
⁷Department of Hematology, University Hospital of Salamanca, Salamanca, Spain
⁸Department of Hematology, Hospital Universitario Lozano Blesa, Zaragoza, Spain
⁹Hospital Virgen de las Nieves, Granada, Spain
¹⁰Hematology, Salamanca Universitary Hospital, Salamanca, Spain
¹¹Cedars-Sinai Outpatient Cancer Center at the Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA
¹²Department of Immunology, Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands

Bruno Paiva, PhD^1*, Teresa Cedena^2*, Noemi Puig, MD, PhD^3*, Lourdes Cordon^4*, Joaquin Martinez-López, MD.PhD^5*, Enrique M. Ocio, MD, PhD^6*, Miguel T Hernandez^7*, Ana Isabel Teruel, MD^8*, Mercedes Gironella^9*, M Asuncion Echeveste^10*, Laura Rosiñol, MD PhD^11*, Rafael Martinez, MD^12*, Albert Oriol, MD PhD^13*, Jesus Martin^14*, Norma C Gutiérrez^15*, Maria Belen Vidriales, MD, PhD^3*, Joan Blade, MD PhD¹¹, Juan Jose Lahuerta^16*, Maria-Victoria Mateos¹⁷ and Jesus San Miguel, MD PhD^18*

¹Department of Hematology and Immunology, Clinica Universidad de Navarra, Pamplona, Spain
²Hematology Department, Hospital Universitario 12 de Octubre, Madrid, Spain
³Department of Hematology, Hospital Universitario de Salamanca, Salamanca, Spain
⁴Hospital Universitario La Fe, Valencia, Spain
⁵Hematology, Hospital 12 de Octubre, Madrid, Spain
⁶University Hospital of Salamanca, Salamanca, Spain
⁷Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain
⁸Hospital Clinico de Valencia, Valencia, Spain
⁹Hospital Universitari Vall dHebron, Barcelona, Spain
¹⁰Hospital Universitario Donostia, San Sebastian, Spain
¹¹Hospital Clinic de Barcelona, Barcelona, Spain
¹²Hospital Clinico, Madrid, Spain
¹³Institut Català d’Oncologia, Hospital Germans Trias i Pujol, Barcelona, Spain
¹⁴Hospital Universitario Virgen del Rocío, Sevilla, Spain
¹⁵Cancer Research Center (IBMCC-CSIC). University of Salamanca., Salamanca, Spain
¹⁶Hospital 12 de Octubre, Madrid, Spain
¹⁷Hematology Department, University Hospital of Salamanca/IBSAL, Salamanca, Spain
¹⁸Centro de Investigación Médica Aplicada, University of Navarra, Clínica Universidad de Navarra, Pamplona, Spain

Shotaro Tatekawa, MD^1*, Junya Kuroda, MD, PhD^2*, Yoshiaki Chinen, MD^1*, Yuji Shimura, MD^1*, Hisao Nagoshi, MD^1*, Tsutomu Kobayashi, MD, PhD^2*, Eri Kawata, MD, PhD^3*, Nobuhiko Uoshima, MD, PhD^3*, Hiroshi Handa, MD, PhD⁴ and Masafumi Taniwaki^2*

¹Division of Hematology and Oncology, Kyoto Prefectural University of Medicine, Kyoto, Japan
²Division of Hematology and Oncology, Kyoto Prefectural University of Medicine Graduate School of Medical Science, Kyoto, Japan
³Department of Hematology, Japanese Red Cross Kyoto Daini Hospital, Kyoto, Japan
⁴Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Gunma, Japan

Manisha Bhutani, MD¹, Qing Zhang, Ph.D.², Sarah A Baxter, PhD^3*, Lawrence J Druhan, PhD³, Bart Barlogie⁴, Pieter Sonneveld, MD, PhD⁵, Belinda R Avalos, MD³, Edward A. Copelan, MD⁶ and Saad Z Usmani, MD, FACP⁷

¹Levine Cancer Institute/Carolinas Healthcare System, Charlotte, NC
²Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Charlotte, NC
³Department of Hematologic Oncology and Blood Disorders, The Levine Cancer Institute, Carolinas HealthCare System, Charlotte, NC
⁴Mount Sinai School of Medicine, New York, NY
⁵Department of Hematology, Erasmus MC, Rotterdam, Netherlands
⁶Carolinas Health Care, Levine Cancer Center, Charlotte, NC
⁷Levine Cancer Institute/Carolinas Healthcare System,, Charlotte, NC

Jayakumar R. Nair, PhD, MSc, BSc^1*, Louise Carlson, BS^2* and Kelvin P. Lee, MD³

¹Dept. of Immunology, Buffalo, NY
²immunology, Roswell Park Cancer Institute, Buffalo, NY
³Departments of Medicine and Immunology, Roswell Park Cancer Institute, Buffalo, NY

Hyungwoo Cho, M.D.^1*, Dok Hyun Yoon, MD, PhD^2*, Kihyun Kim³, Sung-Soo Yoon⁴, Chang-Ki Min, M.D., Ph.D^5*, HyeonSeok Eom, M.D., Ph.D⁶, Jin Seok Kim^7*, Je-Jung Lee⁸, Jae Hoon Lee⁹ and Cheolwon Suh¹⁰

¹Departments of Internal medicine, University of Ulsan College of medicine, Asan Medical Center, Seoul, South Korea
²Department of Oncology, University of Ulsan College of Medicine and Asan Medical Center, Seoul, South Korea
³Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
⁴Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea
⁵Hematology, Catholic BMT Center, Seoul St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, South Korea
⁶National Cancer Ctenter, Goyang-Si, South Korea
⁷Yonsei University College of Medicine, Seoul, South Korea
⁸Department of Hematology-Oncology,Chonnam National University Hwasun Hospital, Hwasun, South Korea
⁹Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, South Korea
¹⁰Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea

Mu Hao, MD, PhD^1*, Meirong Zang, PhD^1*, Yan Xu, MD, PhD^2*, Yu Qin, MD, PhD^1*, Lei Zhao, MD, PhD^3*, Shuhui Deng, MD, PhD^1*, Weiwei Sui, MD^1*, Gang An, MD.PhD^4*, Zengjun Li, MD, PhD^1*, Yi Shuhua, MD, PhD^1*, Fenghuang Zhan, MD, PhD⁵ and Lugui Qiu, MD, PhD¹

¹State Key Lab of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China
²lymphoma & myeloma department, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China
³Department of Molecular Physiology and Biophysics, University of Iowa, Iowa city, IA
⁴Harvard Medical School, the Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Boston, MA
⁵Department of Internal Medicine, University of Iowa, Iowa city, IA

Raphaël Szalat, MD^1,2*, Mehmet Kemal Samur, PhD^3*, Alice Cleynen, PhD^3*, Anne Calkins^4*, Matija Dreze^4*, Yu-Tzu Tai, PhD¹, Stephane Minvielle^5*, Herve Avet-Loiseau^6*, Kenneth C. Anderson, MD¹, Jean-Paul Fermand², Jean-Bernard Lazaro, PhD^4* and Nikhil C. Munshi, MD^1,7

¹Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
²Service d'Immuno-Hematologie, Hopital Saint-Louis, APHP, Paris, France
³Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA
⁴Dana-Farber Cancer Institute, Boston, MA
⁵Centre Hospitalier Universitaire de Nantes, Unité Mixte de Genomique du Cancer, Nantes, France
⁶IUCT-Oncopole, Toulouse, France
⁷VA Boston Healthcare System, West Roxbury, MA

Tina Bagratuni^1*, Nefeli Mavrianou^1*, Efstathios Kastritis, MD^1*, Christine Liakos^1*, Evangelos Terpos, MD¹ and Meletios A. Dimopoulos²

¹Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
²National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

Bangzheng Chen, PhD, Gareth J Morgan, MD PhD, Bart Barlogie, MD, PhD and Joshua Epstein, DSc

Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, AR

Min-Gu Kang, M.D.^1*, Hye-Ran Kim, Ph.D.^2*, Jun Hyung Lee, M.D.^1*, Thashma Pemmanda Ganapathy, M.S.^3*, Seung-Hyeon Yang, B.S.^3*, Moinul Hoque, B.S.^3*, Ra-Young Park, Ph.D.^3*, Seung Jung Kee, M.D., Ph.D.^4*, Soo Hyun Kim, M.D., Ph.D.^1*, Jong-Hee Shin, M.D., Ph.D.⁴, Soon-Pal Suh, M.D., Ph.D.^4* and Myung-Geun Shin, M.D., Ph.D.¹

¹Laboratory Medicine, Chonnam National University Hwasun Hospital, Hwasun, South Korea
²Environmental Health Center for Childhood Leukemia and Cancer, Chonnam National University Hwasun Hospital, Hwasun, South Korea
³Laboratory Medicine and Molecular Diagnostics/Mitochondrial Research Laboratory, Chonnam National University Hwasun Hospital, Hwasun, South Korea
⁴Laboratory Medicine, Chonnam National University Hospital, Gwangju, South Korea

Helene Caillon^1*, Michel Attal², Philippe Moreau, MD, PhD^3* and Thomas Dejoie^1*

¹Biochemistry Laboratory, Nantes University Hospital, Nantes, France, Nantes, France
²Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France
³Department of Hematology, Nantes University Hospital, Nantes, France

Carlos Fernández de Larrea^1*, Xavier Calvo^2*, Natalia Tovar^1*, Ester Lozano^1*, Xavier Setoain^3*, Manel Juan^4*, Tania Díaz^1*, Laura Rosiñol^1*, Montserrat Elena^5*, Mª Teresa Cibeira^1*, Ignacio Isola^1*, Maria Rozman^2*, Juan I. Aróstegui^4*, Jordi Yagüe^4* and Joan Bladé, MD¹

¹Department of Hematology, Amyloidosis and Myeloma Unit. Hospital Clínic, IDIBAPS, Barcelona, Spain
²Department of Hematopathology, Amyloidosis and Myeloma Unit. Hospital Clínic, IDIBAPS, Barcelona, Spain
³Department of Nuclear Medicine, Amyloidosis and Myeloma Unit. Hospital Clínic, IDIBAPS, Barcelona, Spain
⁴Department of Immunology, Amyloidosis and Myeloma Unit. Hospital Clínic, IDIBAPS, Barcelona, Spain
⁵Department of Biochemistry, Amyloidosis and Myeloma Unit. Hospital Clínic, IDIBAPS, Barcelona, Spain

Meera Mohan^1*, Rohan Samant^2*, Larry J Suva^3*, Corey O Montgomery^3*, Daisy V. Alapat, MD⁴, Roy Morello^5*, Frits van Rhee, MD, PhD¹, Sarah Waheed, MD^1*, Sharmilan Thanendrarajan, MD¹, Carolina Schinke, MD^1*, Christoph Heuck, MD¹, Yogesh Jethava, MD^1*, Donald Johann, MD, MS¹, Bart Barlogie, MD, PhD¹, Faith E Davies, MD¹, Gareth J Morgan, MD PhD¹ and Maurizio Zangari, MD¹

¹Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, AR
²Department of Radiology, University of Arkansas for Medical Sciences, Little Rock, AR
³Department of Orthopaedic Surgery, Center for Orthopaedic Research,, University of Arkansas for Medical Sciences, Little Rock, AR
⁴Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR
⁵Department of Physiology & Biophysics, University of Arkansas for Medical Sciences, Little Rock, AR

Natalie Scott Callander, MD^1,2, Cesar O. Freytes, MD³, Suhong Luo, MPH^4* and Kenneth R Carson, MD, PhD^5,6

¹University of Wisconsin Carbone Cancer Center, Madison, WI
²Williams S. Middleton Memorial Veterans Hospital, Madison, WI
³Medicine, Audie L. Murphy Memorial Veterans Hospital, San Antonio, TX
⁴Research Service, St Louis Veterans Administration Medical Center, St. Louis, MO
⁵Medicine, St Louis Veterans Administration Medical Center, St Louis, MO
⁶Washington University School of Medicine, Saint Louis, MO

Arnab Ghosh, MD, PhD^1*, Nicole Carreau, MD^1*, Alessandra Moscatello^2*, Adeeb Rahman, PhD^3*, Jingjing Qi^3*, Seunghee Kim-Schulze, PhD^3*, Shyamala C. Navada, MD⁴, Ajai Chari, MD⁵, Hearn Jay Cho, MD, PhD⁵, Sundar Jagannath, MD⁶ and Samir Parekh, MD⁷

¹Internal Medicine, Mount Sinai Hospital, New York, NY
²Mount Sinai Hospital, New York, NY
³Human Immune Monitoring Core, Icahn School of Medicine at Mount Sinai, New York, NY
⁴Division of Hematology/Oncology and Tisch Cancer Institute, Mount Sinai School of Medicine, New York, NY
⁵Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
⁶Tisch Cancer Institute / Multiple Myeloma Program, Mount Sinai School of Medicine, New York, NY
⁷Hematology and Medical Oncology, Mount Sinai School of Medicine, New York, NY

Even Holth Rustad^1*, Hong Yan Dai, PhD^2*, Eivind Coward, PhD^3*, Kristine Misund, PhD^1*, Anders Sundan, PhD^1* and Anders Waage, MD, PhD^1,4

¹KG Jebsen Center for Myeloma Research, Norwegian University of Science and Technology, Trondheim, Norway
²Department of Pathology and Medical Genetics, St. Olavs Hospital, Trondheim, Norway
³Bioinformatics Core Facility, Norwegian University of Science and Technology, Trondheim, Norway
⁴Department of Hematology, St. Olavs University Hospital, Trondheim, Norway

Taxiarchis Kourelis, MD, Francis Buadi, MD, Morie A Gertz, MD, Shaji Kumar, MD, Martha Q. Lacy, MD, Prashant Kapoor, MD, Ronald S. Go, MD, John A. Lust, MD, PhD, Suzanne R. Hayman, MD, S. Vincent Rajkumar, Steven R. Zeldenrust, MD, PhD, Stephen J. Russell, MD, PhD, David Dingli, MD, PhD, FRCP, Yi Lin, MD, PhD, Nelson Leung, MD, Robert A. Kyle, MD, Wilson I. Gonsalves, MD^* and Angela Dispenzieri, MD

Division of Hematology, Mayo Clinic, Rochester, MN

Brian C.-H. Chiu, PhD¹, Jin-Hua Chen, PhD^2*, Yu-Chun Yen, MS^2*, Gregory S. Calip, PharmD, MPH, PhD^3,4*, Chun-Ru Chien, MD, PhD^5*, Habibul Ahsan, MD, MMedSc^1*, Ya-Chen T Shih, PhD^6* and Kuang-Fu Cheng, PhD^2*

¹Department of Public Health Sciences, University of Chicago, Chicago, IL
²Biostatistics Center, Taipei Medical University, Taipei, Taiwan
³Center for Pharmacoepidemiology and Pharmacoeconomic Research, University of Illinois at Chicago, Chicago, IL
⁴Department of Pharmacy Systems, Outcomes and Policy, University of Illinois at Chicago, Chicago, IL
⁵Department of Radiation Oncology, China Medical University Hospital, Taichung, Taiwan
⁶Department of Health Services Research, University of Texas MD Anderson Cancer Center, Houston, TX

Shuji Ozaki, MD, PhD¹, Takayuki Saitoh, MD, PhD^2*, Hiroshi Handa, MD, PhD³, Hirokazu Murakami, MD², Kenshi Suzuki⁴, Naoki Takezako, MD, PhD⁵, Jun Konishi^6*, Kazutaka Sunami⁶, Yoshiaki Kuroda^7*, Mitsuhiro Itagaki, MD^8*, Hideki Asaoku, MD^9*, Eiichi Nagura, MD^10* and Kazuyuki Shimizu, MD¹¹

¹Department of Hematology, Tokushima Prefectural Central Hospital, Tokushima, Japan
²Department of Laboratory Sciences, Gunma University, Graduate School of Health Sciences, Maebashi, Japan
³Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Gunma, Japan
⁴Department of Hematology, Japanese Red Cross Medical Center, Tokyo, Japan
⁵Department of Hematology, National Hospital Organization Disaster Medical Center of Japan, Tachikawa, Japan
⁶Department of Hematology, National Hospital Organization Okayama Medical Center, Okayama, Japan
⁷Department of Hematology, Hiroshima University Hospital, Hiroshima, Japan
⁸Internal Medicine, Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital, Hiroshima, Japan
⁹Department of Laboratory, Hiroshima Red Cross Hospital, Hiroshima, Japan
¹⁰Department of Hematology, Chutoen General Medical Center, Kakegawa, Japan
¹¹Department of Hematology, Tokai Central Hospital, Kakamigahara, Japan

Miroslav Koulnis, PhD^1*, Homare Eda, MD, PhD^1*, Loredana Santo, MD^1*, Ka Tat Siu, PhD¹, Janani Ramachandran, MA^1*, Cristina Panaroni, PhD^1*, Takaaki Tanaka, MD, PhD^2* and Noopur S. Raje, MD¹

¹Massachusetts General Hospital Cancer Center, Boston, MA
²Dept. of Orthopaedic surgery, NHO Utsunoiya National Hospital, Utsunoiya, Japan

Shaji K Kumar, MD¹, Jae Hoon Lee², Meletios A. Dimopoulos³, Evangelos Terpos, MD⁴, Efstathios Kastritis, MD^4*, Wee Joo Chng, MD, PhD⁵, Artur J. Jurczyszyn, MD, PhD^6*, Hiroshi Handa, MD, PhD⁷, Shuji Ozaki, MD, PhD⁸, Xavier Leleu, MD, PhD⁹, Philippe Moreau, MD, PhD^10*, Juan José Lahuerta, MD PhD^11*, Chaim Shustik, MD¹², Daniel Dirck Waller, PhD^13*, Meral Beksac, MD¹⁴, Ravi Vij, MD, MBA¹⁵, Kihyun Kim¹⁶, Jin Seok Kim, M.D., Ph.D.^17*, Ashraf Z Badros, MD¹⁸, Melissa Alsina, MD¹⁹ and Brian G. M. Durie, MD²⁰

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, South Korea
³National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
⁴Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
⁵Haematology-Oncology, National University Health Systems, Singapore, Singapore
⁶Department of Haematology, Jagiellonian University Medical College, Kraków, Poland
⁷Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Gunma, Japan
⁸Department of Hematology, Tokushima Prefectural Central Hospital, Tokushima, Japan
⁹Service d'h, hopital la miletrie, POITIER, France
¹⁰Nantes University Hospital, Hôtel Dieu, Nantes, France
¹¹Hematology, Hospital Universitario 12 de Octubre, Madrid, Spain
¹²Division of Haematology, McGill University Health Center, Montreal, QC, Canada
¹³Cedars Cancer Centre, McGill University Health Centre Glen Site, Montreal, QC, Canada
¹⁴Department of Hematology, Ankara University School of Medicine, Ankara, Turkey
¹⁵Department of Medicine, Division of Oncology, Washington University School of Medicine, St Louis, MO
¹⁶Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea
¹⁷Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea
¹⁸Department of Medicine and Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore, MD
¹⁹Malignant Hematology, Moffitt Cancer Center, Tampa, FL
²⁰Cedars-Sinai Outpatient Cancer Center at the Samuel Oschin Comprehensive Cancer Institute, Los Angeles, CA

Ajay K. Nooka, MD, MPH¹, Jonathan L. Kaufman, MD¹, A. Tuba Karagulle Kendi, MD^2*, Yan Li^3*, Chikaodili O Obidike^3*, Charise Gleason, MSN, ANP-BC, AOCNP^1*, Lawrence H Boise, Ph.D.^1* and Sagar Lonial, MD^3,4

¹Division of BMT, Winship Cancer Institute, Emory University, Atlanta, GA
²Department of Nuclear Medicine, Emory University, Atlanta, GA
³Winship Cancer Institute, Emory University, Atlanta, GA
⁴Winship Cancer Institute of Emory University, Department of Hematology and Medical Oncology, Atlanta, GA

Jumpei Teramachi, DDS, PhD^1*, Masahiro Hiasa, PhD, DDS^2,3*, Asuka Oda^2*, Hirofumi Tenshin, DDS^2,4*, Ryota Amachi, DDS, PhD^2,4*, Takeshi Harada, MD, PhD^2*, Derek Hanson^2*, Keiichiro Watanabe, DDS, PhD^2,4*, Shiro Fujii, MD^2*, Kumiko Kagawa, MD^5,6*, Shingen Nakamura, MD, PhD^2*, Hirokazu Miki, MD, PhD^7*, Itsuro Endo, MD, PhD^2*, Shuji Ozaki, MD, PhD⁸, Toshio Matsumoto, MD, PhD^9* and Masahiro Abe, MD, PhD^2*

¹Department of Histology and Oral Histology, Tokushima University, Tokushima, Japan
²Department of Hematology, Endocrinology and Metabolism, Tokushima University, Tokushima, Japan
³Department of Biomaterials and Bioengineering, Tokushima University, Tokushima, Japan
⁴Department of Orthodontics and Dentofacial Orthopedic, Tokushima University, Tokushima, Japan
⁵Department of Hematology, Endocrinology and Metabolism, Tokushima University, Tokusima City, Japan
⁶Tokushima University, Tokushima, Japan
⁷Department of transfusion and cell therapy, Tokushima University Hospital, Tokushima, Japan
⁸Hematology, Tokushima Prefectural Central Hospital, Tokushima, Japan
⁹Fujii Memorial Institute of Medical Sciences, Tokushima University, Tokushima, Japan

Yu Wu, MD, PhD^1,2, Xinyi Chen^3* and Yuhuan Zheng^1*

¹Hematology Research Laboratory, West China Hospital, Sichuan University, Chengdu, China
²Department of Hematology, West China Hospital, Sichuan University, Chengdu, China
³Sichuan University, West China Hospital, Chengdu, China

Mi Hyun Bae, MD, PhD^1*, Sang Hyuk Park, MD, PhD^2*, Chan-Jeoung Park, MD, PhD¹, Bo Hyun Kim, MD^1*, Young-Uk Cho, MD, PhD¹, Seongsoo Jang, MD, PhD¹, Dong-Hyun Lee, MD^1*, Eul-Ju Seo, MD, PhD^1*, Jung-Hee Lee, MD, PhD^3*, Dok Hyun Yoon, MD, PhD^4* and Cheolwon Suh⁵

¹Department of Laboratory Medicine, University of Ulsan College of Medicine and Asan Medical Center, Seoul, South Korea
²Department of Laboratory Medicine, Pusan National University School of Medicine, Pusan National University Hospital, Busan, South Korea
³Department of Hematology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea
⁴Department of Oncology, University of Ulsan College of Medicine and Asan Medical Center, Seoul, South Korea
⁵Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea

Hang Quach, MD^1*, Daniel North, MBBS^2*, Susanna Freddi^3*, Shuh Y Tan, FRACP^4*, Lenny Straszkowski^5* and Harshal Nandurkar, PhD, FRACP, FRCPA⁶

¹University of Melbourne, St. Vincent's Hospital, Victoria, Australia
²St.Vincent's Hospital, Fitzroy, Australia
³Monash University, Clayton, Australia
⁴University of Melbourne, St.Vincent's Hospital, Melbourne, Australia
⁵St.Vincent's Institute, Fitzroy, Australia
⁶Australian Centre for Blood Diseases, Prahran, Australia

Brian S White, PhD^1,2*, Irena Lanc, PhD^1,3*, Daniel Auclair, PhD^4*, Robert Fulton, PhD^2*, Mark A Fiala, BS, CCRP^1*, Justin King^1*, Gregory Ahmann, BS⁵, Mary Derome, MS^4*, Elaine R Mardis, PhD^2*, Joan Levy, PhD^4*, Ravi Vij, MD, MBA¹, John F. DiPersio, MD, PhD¹ and Michael Tomasson, MD¹

¹Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO
²Washington University School of Medicine, Saint Louis, MO
³McDonnell Genome Institute, Washington University, Saint Louis, MO
⁴Multiple Myeloma Research Foundation, Norwalk, CT
⁵Division of Hematology - Oncology, Mayo Clinic, Scottsdale, AZ

Paul Dowling^1*, Kay Reen Ting^2,3*, Justine Meiller^2*, Shane Kelly^2*, Martin Clynes^2* and Peter O'Gorman^2,3

¹Dept of Biology, Maynooth University, Maynooth, Ireland
²National Institute for Cellular Biotechnology, Dublin City University, Dublin 9, Ireland
³Department of Haematology, Mater Misericordiae University Hospital, Dublin 7, Ireland

Catherine Randall Paschal, PhD^1*, Jens C Eickhoff, PhD^2*, Aric C Hall, MD^3*, Jennifer Laffin, PhD, FACMG^1*, Natalie Scott Callander, MD³ and Catherine P Leith, MBBChir⁴

¹Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI
²Department of Biostatistics & Medical Informatics, University of Wisconsin, Madison, WI
³Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI
⁴Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI

Luiza soares Vieira, MD^1*, Edvan de queiroz Crusoe, MD, MsC^1,2*, Manuella de S. Sampaio Almeida, MD, PhD^1*, Lais Sousa, MD^3*, ana Lucia Perez, MD^1*, Priscilla Cury, md^4*, Marina Rossato, MD^1*, Fabiana Higashi, MD^5*, ana Luiza Dias, MD^1*, anna Carolina Castro, MD^1*, Carlos Chiattone, MD, PhD⁶ and Vania T M Hungria, MD PhD⁷

¹Disciplina de Hematologia e Oncologia da Faculdade de Ciências Médicas da Santa Casa de São Paulo, sao paulo, Brazil
²Hospital Universitário Professor Edgar Santos- Universidade Federal da Bahia- HUPES- UFBA, salvador, Brazil
³Federal University of Bahia, Salvador, Brazil
⁴Disciplina de Hematologia e Oncologia da Faculdade de Ciências Médicas da Santa Casa de São Paulo, Sao Paulo, Brazil
⁵Disciplina de Hematologia e Oncologia da Faculdade de Ciências Médicas da Santa Casa de São Paulo, SAO PAULO, Brazil
⁶Disciplina de Hematologia e Hemoterapia, Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil
⁷Disciplina de Hematologia e Oncologia da Faculdade de Ciências Médicas da Santa Casa de Misericórdia São Paulo, Sao Paulo, Brazil

Ramesh Babu, Ph.D., MBA^1* and Prasad Koduru, Ph.D.^2*

¹InteGen LLC, Orlando, FL
²UTSouthWestern Medical Center, Dallas, TX

Mehmet K Samur, Ph.D^1,2*, Stephane Minvielle^3*, Florence Magrangeas^3*, Giovanni Parmigiani, PhD^1*, Kenneth C Anderson⁴, Philippe Moreau, MD^5*, Michel Attal⁶, Hervé Avet-Loiseau, MD^7* and Nikhil C. Munshi, MD^2,8

¹Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA
²LeBow Institute for Myeloma Therapeutics and Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
³Centre Hospitalier Universitaire de Nantes, Unité Mixte de Genomique du Cancer, Nantes, France
⁴The Jerome Lipper Multiple Myeloma Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
⁵Nantes University Hospital, Hôtel Dieu, Nantes, France
⁶Institut Universitaire du Cancer de Toulouse-Oncopole, Toulouse, France
⁷Centre de Recherche en Cancérologie de Toulouse Institut National de la Santé, Toulouse, France
⁸VA Medical Hospital, Boston, MA

Priya Khoral^1,2*, Robert J Guo^1,2*, Jahangir Abdi, PhD,^1,2* and Hong Chang, MD, PhD^1,2

¹University Health Network, Department of Laboratory Hematology, Toronto, ON, Canada
²University of Toronto, Department of Laboratory Medicine and Pathobiology, Toronto, ON, Canada

Ximena Camacho, MSc^1*, Camila Machado, Ph D^2*, maria Fernanda Garcia, Ph D^3*, Marcelo Fernandez, Ph D^3*, Omar Alonso^4*, Hugo Cerecetto^3*, Roger Chammas^2*, Juan Pablo Gambini^4*, Pablo Cabral, Ph D^3* and Eloisa Riva, MD⁵

¹Centro de Investigaciones Nucleares, Universidad de la República, Montevideo, Uruguay
²Departamento de Oncologia, Universidad de San Pablo, San Pablo, Brasil., San Pablo, Brazil
³Centro de Investigaciones Nucleares, Facultad de Ciencias, montevideo, Uruguay
⁴Medicina Nuclear, Hospital de Clinicas, montevideo, Uruguay
⁵Hematology Department, Hospital de Clínicas, Montevideo, Uruguay

Antonia Reale, Oncologist in training^1*, Tiffany T. Khong, BSc, PhD^2,3, Sridurga Mithraprabhu, Post doc^4*, Ioanna Savvidou, MD, PhD student^5*, Malarmathy Ramachandran^4* and Andrew Spencer^4,5,6

¹ACBD, Monash University/The alfred, Melbourne, Australia
²Myeloma Research Group, Alfred Hospital, Melbourne, Australia
³Myeloma Research Group, ACBD, Monash University & Alfred Hospital, Melbourne, Australia
⁴Myeloma Research Group, ACBD, Alfred Health-Monash University, Melbourne, Australia
⁵Myeloma Research Group, Alfred Hospital-Monash University, Melbourne, Australia
⁶Department of Haematology, Monash University and Alfred Hospital, Melbourne, Australia

Juraj Adamik, PhD^1*, Jixin Ding, PhD^2*, Wei Zhao^3*, Peng Zhang, Ph.D.^4*, Quanhong Sun^5*, G. David Roodman, MD, PhD^6,7 and Deborah Lynn Galson, PhD¹

¹Department of Medicine, Hematology-Oncology, University of Pittsburgh, Pittsburgh Cancer Institute, Pittsburgh, PA
²Indiana University, Indianapolis, IN
³Medicine/Hematology-Oncology, Indiana University, Indianapolis, IN, Indianapolis
⁴Department of Medicine, Hematology-Oncology, University of Pittsburgh, Pittsburgh Cancer Institute, Pittsburgh
⁵Department of Medicine, Hematology-Oncology Division, UPCI University of Pittsburgh, Pittsburgh
⁶Richard L. Roudenbush Veterans Administration Medical Center, Indianapolis, IN
⁷Medicine/Hematology-Oncology, Indiana University, Indianapolis, IN