Hun Ju Lee, MD^1*, Miguel Gallardo, PhD^2*, Xiaorui Zhang, BS^2*, Huaxian Ma, BS^2*, Alfonso Quintas-Cardama, MD², Yuan Qi^3*, Xiaoping Su, PhD^4* and Sean M. Post, PhD²

¹Department of Lymphoma & Myeloma, MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, MD Anderson Cancer Center, Houston, TX
³Department of Bioinformatics and Computational Biology, MD Anderson Cancer Center, Houston, TX
⁴Bioinformatics and Computational Biology, MD Anderson Cancer Center, Houston, TX

Yo-Ting Tsai, MS¹, Gerard Lozanski, MD^2*, Amy M. Lehman, MAS^3*, Ellen Sass^4*, Erin K. Hertlein, PhD⁵, Santosh Salunke^1*, Ching-Shih Chen, PhD^1*, Michael R. Grever, MD⁵, John C. Byrd, MD⁶ and David M. Lucas, PhD⁶

¹College of Pharmacy, The Ohio State University, Columbus, OH
²Pathology, The Ohio State University, Columbus, OH
³Center for Biostatistics, Department of Bioinformatics, The Ohio State University, Columbus, OH
⁴Department of Internal Medicine, College of Medicine, The Ohio State University, Columbus, OH
⁵Department of Internal Medicine, Division of Hematology, The Ohio State University, Columbus, OH
⁶Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, OH

Andrea Ghelli Luserna Di Rora^1*, Ilaria Iacobucci, PhD^2*, Enrica Imbrogno^3*, Enrico Derenzini, MD^3*, Anna Ferrari, PhD^4*, Viviana Guadagnuolo, PhD^4*, Valentina Robustelli^3*, Simona Soverini⁵, Cristina Papayannidis, MD, PhD⁶, Maria Chiara Abbenante, MD^4*, Michele Cavo, MD^2* and Giovanni Martinelli, MD, PhD⁶

¹DIMES, Department of Hematology and Medical Sciences “L. and A. Seràgnoli”, Bologna, Italy, Bologna, Italy
²"Seràgnoli" Institute of Hematology, University of Bologna, Bologna, Italy
³DIMES, Department of Hematology and Medical Sciences “L. and A. Seràgnoli”, University of Bologna, Bologna, Italy
⁴University of Bologna, Bologna, Italy
⁵Institute of Hematology, S.Orsola-Malpighi University Hospital, Bologna, Italy
⁶Bologna University School of Medicine, Bologna, Italy

Rosaria De Filippi, MD, PhD^1,2*, Michele Cillo, ScD^1*, Stefania Crisci, ScD^1*, Sara Mele, BS^1*, Serena Zanotta, ScD^1*, Angela De Monaco, ScD^1*, Domenico Galati, MD^1*, Giancarla Iaccarino, ScD^1*, Raffaele Di Francia, ScD^1*, Emanuela Morelli, MD^1*, Gianpaolo Marcacci, MD^1*, Cristina Becchimanzi, MD^1*, Attilio Guarini, MD^3*, Ferdinando Frigeri, MD, PhD^1*, Gaetano Corazzelli, MD^1* and Antonello Pinto, MD^1*

¹Hematology-Oncology and Stem Cell Transplantation Unit, Istituto Nazionale Tumori, Fondazione 'G. Pascale', IRCCS, Naples, Italy
²Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy
³Hematology, Ospedale oncologico 'Giovanni Paolo II', I.R.C.C.S., Bari, Italy

Meirong Zang^1*, Fengyan Jin^2*, Lanting Liu^1*, Gang An, MD.PhD^1*, Xiaoqi Qin, MD.^1*, Xiaoyan Feng^1*, Yan Xu, MD, PhD^1*, Mu Hao, MD, PhD^1*, Wen Zhou, Ph.D^1,3* and Lugui Qiu, MD, PhD¹

¹State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China
²Cancer Center, The First Hospital of Jilin University, Changchun, China
³Cancer Research Institute, Central South University; Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education;Key Laboratory of Carcinogenesis, National Health and Family Planning Commission, Changsha, China

Rosaria De Filippi, MD, PhD^1,2*, Stefania Crisci, ScD^2*, Michele Cillo, ScD^2*, Sara Mele, BS^2*, Angela De Monaco, ScD^2*, Domenico Galati, MD^2*, Serena Zanotta, ScD^2*, Gaetana Capobianco, MD^2*, Francesco Volzone, MD^2*, Manuela Arcamone, MD^2*, Piera Maiolino, PharmD^3*, Mariangela Saggese, PharmD^2*, Gaetano Corazzelli, MD^2*, Ferdinando Frigeri, MD, PhD^2*, Thomas Mehrling, MD, PhD^4* and Antonello Pinto, MD^2*

¹Department of Clinical Medicine and Surgery, Federico II University, Naples, Italy
²Hematology-Oncology and Stem Cell Transplantation Unit, Istituto Nazionale Tumori, Fondazione 'G. Pascale', IRCCS, Naples, Italy
³Pharmacy Unit, Istituto Nazionale Tumori, Fondazione 'G. Pascale', IRCCS, Naples, Italy
⁴Mundipharma-EDO GmbH, Basel, Switzerland

Rick Sorensen, BS^*, Sarah Meadows^*, Anella Yahiaoui, BS^*, Li Li, PhD, Peng Yue, PhD^*, Adam Kashishian, BS^*, Christophe Queva, PhD and Stacey Tannheimer, PhD^*

Gilead Sciences, Foster City, CA

Luigi Rigacci^1*, Gabriele Perrone^2*, Stefania Nobili^2*, Sofia Kovalchuk^1*, Benedetta Puccini^1*, Federica Lancia^1*, Renato Tassi^2*, Marco Brugia^2*, Ida Landini^2*, Lara Mannelli^1*, Gemma Benelli^1*, Cristina Napoli^2*, Emanuele Cencini^3*, Alberto Fabbri^4*, Lorenzo Iovino^5*, Mario Petrini⁵, Silvia Birtolo^6*, Alessandro Melosi^7*, Varesco Martini^8*, Simone Santini^9*, Carla Breschi^10*, Paolo Bernardeschi^11*, Carmelo Bengala^12*, Alberto Bosi, MD¹ and Enrico Mini^2*

¹Hematology Department, University and Hospital Careggi, Firenze, Italy
²Dipartimento di Scienze della Salute, University of Florence, Firenze, Italy
³Hematology Unit, Ospedale Santa Maria alle Scotte and University of Siena, Siena, Italy
⁴Az. Ospedaliera Universitaria Senese, Siena, Italy
⁵Hematology Department, University of Pisa, Pisa, Italy
⁶Oncology Department, Hospital, Pescia, Italy
⁷Oncology, Hospital, Lucca, Italy
⁸Oncology, Hospital, Firenze, Italy
⁹Oncology, Hospital, Prato, Italy
¹⁰Oncology, Hospital, Pistoia, Italy
¹¹Oncology, Hospital, Empoli, Italy
¹²Oncology, Hospital, Grosseto, Italy

Paul J. Hengeveld, B.Sc.^1,2*, Geoffrey M. Matthews, PhD^1*, Yiguo Hu, MD, PhD^1*, Michal Sheffer, PhD^1*, Megan A. Bariteau, BSc^1*, Haley I. Poarch^1*, Eugen Dhimolea, PhD^1* and Constantine S Mitsiades, MD, PhD¹

¹Dept. of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
²Department of Hematology, Academic Medical Centre, University of Amsterdam, Amsterdam, Netherlands

Joan Ballesteros¹, Lydia Scarfo^2*, Mattias Mattsson^3*, Aliki Xochelli^4*, Pamela Ranghetti^5*, Daniel Primo^1*, Alicia Robles^1*, Julian Gorrochategui^1*, Joaquin Martinez-Lopez^6*, Javier De la Serna⁶, Marcos González, MD, PhD^7*, Veerendra Munugalavadla⁸, Richard Rosenquist⁹, Kostas Stamatopoulos^4*, Christophe Quéva, Ph.D.^8* and Paolo Ghia, MD, PhD¹⁰

¹Vivia Biotech, Madrid, Spain
²Unit of Lymphoid Malignancies, Department of Onco-Hematology, San Raffaele Scientific Institute, Milan, Italy
³Uppsala University, Uppsala, Sweden
⁴Institute of Applied Biosciences, CERTH, Thessaloniki, Greece
⁵Università Vita-Salute San Raffaele and Ospedale San Raffaele, Milano, Italy
⁶Hospital Universitario 12 de Octubre, Madrid, Spain
⁷Hospital Clínico Universitario de Salamanca, Salamanca, Spain
⁸Gilead Sciences, Foster City, CA
⁹Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
¹⁰Università Vita-Salute San Raffaele and IRCCS Istituto Scientifico San Raffaele, Milano, Italy

Keith J. August, MD, MS¹, Leon van Haandel, PhD^2* and J. Steven Leeder, PharmD, PhD^2*

¹Division of Hematology/Oncology, Children's Mercy Hospital, Kansas City, MO
²Division of Clinical Pharmacology and Therapeutic Innovation, Children's Mercy Hospital, Kansas City, MO

Marsha L. Crochiere, PhD^1*, Stefan Hannus, PhD^2*, Kerrin Hansen^2*, Frank Becker, PhD^2*, Joel Ellis, PhD^1*, Margaret S. Lee, PhD¹ and Yosef Landesman, PhD^1*

¹Karyopharm Therapeutics Inc., Newton, MA
²Intana Bioscience GmbH, Planegg/Martinsried, Germany

Yana Pikman, MD¹, Andrew Furman, BA^2*, Emily S. Lee^2*, Andrew E. Place, MD, PhD¹, Gabriela Alexe, PhD^2*, Rebecca Modiste, RT(N), LAT^3*, Prafulla Gokhale, PhD^3*, Sunkyu Kim, PhD^4*, Lewis B. Silverman, MD¹ and Kimberly Stegmaier, MD¹

¹Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, MA
²Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA
³Dana-Farber Cancer Institute, Boston, MA
⁴Novartis Institute for Biomedical Research, Cambridge, MA