-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

501. Hematopoietic Stem and Progenitor Biology: Poster II

Hematopoietic Stem and Progenitor Biology Program: Oral and Poster Abstracts
Type: Poster
Sunday, December 6, 2015: 6:00 PM-8:00 PM
Hall A, Level 2 (Orange County Convention Center)

Murakami Shohei, PhD1*, Masayuki Yamamoto, MD, PhD2 and Hozumi Motohashi, MD, PhD1*

1Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan
2Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan

Karen K Vo, BS1,2, Danuta Jadwiga Jarocha, PhD1*, Randolph B Lyde Jr., BS1,2, Spencer Sullivan, MD3*, Deborah French, PhD4* and Mortimer Poncz, MD4,5

1Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA
2Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, PA
3Division of Hematology, University of Mississippi Medical Center, Jackson, MS
4Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA
5Department of Pediatrics, University of Pennsylvania, Philadelphia, PA

Qingsong Qiu, PhD candidate1*, Ping Liu, MD1*, Xuemei Zhao, BS1*, Chun Zhang, MS1*, Donghe Li, BS1*, Ruihong Zhang, BS1* and Ruibao Ren, MD, PhD1,2

1State Key Laboratory of Medical Genomics and Shanghai Institute of Hematology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
2Department of Biology, Brandeis University, Waltham, MA

Seonmi Park1*, Andreia Gianotti-Sommer1*, David H.K. Chui, MD2, Maria Stella Figueiredo, MD, PhD3*, Abdulrahman Alsultan, MD4*, Amein Al-Ali5*, Martin H Steinberg, Professor, of, Medicine6, George J. Murphy, Ph.D7* and Gustavo Mostoslavsky8*

1Center for Regenerative Medicine (CReM), Boston University, Boston, MA
2Department of Medicine, Boston University School of Medicine, Boston, MA
3Hematology and Blood Transfusion Division, Escola Paulista de Medicina / Universidade Federal de Sao Paulo, Sao Paulo SP, Brazil
4Sickle Cell Disease Research Center and Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia
5Center for Research & Medical Consultation, University of Dammam, Dammam, Saudi Arabia
6Department of Medicine/Division of Hematology and Oncology, Boston University School of Medicine, Boston, MA
7Department of Medicine, Center for Regenerative Medicine (CReM), Boston University, Boston, MA
8Department of Medicine, Center for Regenerative Medicine (CReM), Boston University School of Medicine, Boston, MA

Takashi Higo, MD1*, Junji Koya, MD, PhD1*, Yoshiki Sumitomo1,2*, Takako Tsuruta-Kishino, PhD1*, Keisuke Kataoka, MD, Ph.D.3*, Tomohiko Sato, MD, PhD1* and Mineo Kurokawa, MD4

1Department of Hematology & Oncology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan
2Oncology Research Laboratories, Kyowa Hakko Kirin Co., Ltd, tokyo, Japan
3Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
4Department of Hematology and Oncology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan

Yukiko Doi, MD1*, Takafumi Yokota, MD, PhD1, Tomohiko Ishibashi, MD1*, Yusuke Satoh, MD, PhD2, Michiko Ichii, MD, PhD1*, Akira Tanimura, MD, PhD1*, Sachiko Ezoe, MD, PhD1*, Hirohiko Shibayama, MD, PhD1, Kenji Oritani, MD, PhD1* and Yuzuru Kanakura, MD, PhD1

1Department of Hematology and Oncology, Osaka University Graduate School of Medicine, Suita, Japan
2Department of Lifestyle Studies, Kobe Shoin Women's University, Kobe, Japan

Tiago R Matos, MD, MSc1,2*, Hongye Liu1*, Masahiro Hirakawa, MD, PhD3*, Ana Cristina Alho, MD4,5* and Jerome Ritz, MD4,6

1Division of Hematologic Malignancies and Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
2Faculdade de Medicina da Universidade de Lisboa, Instituto de Medicina Molecular, Lisbon, Portugal
3Division of Hematologic Malignancies, Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA
4Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Boston, MA
5Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal
6Harvard Medical School, Boston, MA

Frederik Otzen Bagger, PhD1,2,3,4,5*, Damir Sasivarevic6*, Sina Hadi Sohi6*, Linea Gøricke Laursen1,2,3*, Sachin Pundhir, PhD1,2,3,4*, Ole Winther, PhD7*, Nicolas Rapin, PhD1,2,3,4* and Bo T Porse, PhD1,2,3*

1Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark
2Danish Stem Cell Centre (DanStem), Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
3The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
4Bioinformatics Centre, Department of Biology, Faculty of Natural Sciences, University of Copenhagen, Copenhagen, Denmark
5Current address: Dept. of haematology, Current address: University of Cambridge and EMBL-EBI, Cambridge, England
6Technical University of Denmark, Kgs. Lyngby, Denmark
7DTU Compute, Technical University of Denmark, Kgs. Lyngby, Denmark

Canxin Xu, MD, PhD1,2*, Kyunghee Choi, PhD1,2, Tae-Jin Lee1* and Nagisa Sakurai1*

1Pathology&Immunology, Washington University in St Louis, St Louis, MO
2Developmental, Regenerative and Stem Cell Biology Program, Washington University in St Louis, St Louis, MO

Sasan Zandi, MD PhD1, Faiyaz Notta2,3*, John E. Dick, PhD1, Naoya Takayama4*, Stephanie M Dobson, MSc1*, Olga I Gan, PhD5*, Gavin Wilson6*, Kerstin Kaufmann7*, Jessica McLeod7*, Elisa Laurenti, PhD8*, Cyrille Dunant9*, Mcpherson John6*, Lincoln Stein6* and Yigal Dror, MD, FRCP(C)10

1Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
2Ontario Institute For Cancer Research, Toronto, ON, Canada
3OICR, Toronto, ON, Canada
4UHN, Tokyo, Canada
5Department of Molecular Genetics, University of Toronto, Princess Margaret Cancer Centre, University Health Network, TORONTO, ON, Canada
6OICR, TORONTO, Canada
7UHN, TORONTO, Canada
8Cambridge Stem Cell Institute, Department of Haematology, University of Cambridge, Cambridge, England
9EPFL, Lausanne, Switzerland
10Marrow Failure and Myelodysplasia Program, Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada

Heather A. O'Leary, Ph.D.1, Thomas McNamara2* and Hal E. Broxmeyer, Ph.D.3

1Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN
2Indiana University School of Medicine/ Trinity College, Indianapolis, IN
3Department of Microbiology/Immunology, Indiana University School of Medicine, Indianapolis, IN

Kohta Miyawaki, MD1*, Hiromi Iwasaki, MD, PhD2 and Koichi Akashi, MD, PhD1*

1Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
2Center for Cellular and Molecular Medicine, Kyushu University Hospital, Fukuoka, Japan

Saritha D'Souza, PhD1*, John Maufort, PhD1*, Akhilesh Kumar, PhD1*, James Thomson, D.V.M., PhD2* and Igor Slukvin, MD, PhD1,3

1Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI
2Morgridge Institute for Research, Madison, WI
3Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI

Raedun Clarke, PhD1*, William Kim, PhD2*, Brian Groff, BS2*, Ramzey Abujarour, PhD1*, Megan Robinson, BS1*, Xiaosong Huang, PhD1*, Newsha Sahaf2*, Sarah Raynel, MS1*, Betsy Rezner, BS1*, David Robbins, BS1*, Lisa Guerrettaz, PhD1*, Daniel Shoemaker, PhD1* and Bahram Valamehr, PhD, MBA2*

1Fate Therapeutics, San Diego, CA
2Fate Therapeutics Inc, San Diego, CA

Yoshikazu Matsuoka, Ph.D.*, Keisuke Sumide, Phar.B.*, Hiroshi Kawamura, M.D.*, Ryusuke Nakatsuka, Ph.D.*, Tatsuya Fujioka, M.D., Ph.D.*, Yutaka Sasaki, M.D., Ph.D.* and Yoshiaki Sonoda, M.D., Ph.D.

Department of Stem Cell Biology and Regenerative Medicine, Kansai Medical University, Hirakata, Japan

Tonio Lang*, Friederike Herbst, PhD*, Elias Eckert*, Peer Wünsche*, Shayda Hemmati, PhD*, Tim Kindinger*, Nina Hofmann*, Oksana Zavidij, PhD*, Manfred Schmidt, PhD*, Claudia Ball, PhD* and Hanno Glimm, MD

Department of Translational Oncology, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Heidelberg, Germany

Yan Xiu, MD PhD* and Chen Zhao, MD PhD

University of Iowa, Iowa City, IA

Flavia Guillem, PhD1,2,3*, Michael Dussiot, PhD4*, Sebastien Causse, PhD5,6*, Guillaume Marcion7*, Emilie-Fleur Gautier, PhD4,8*, Julien Rossignol, MD9,10,11,12*, Jean benoit Arlet, MD, PhD13,14*, Mathilde Lamarque, MD3,15,16*, Patrick Mayeux, PhD8,17,18, Frederique Verdier, PhD4,8*, Xiuli An, MD, PhD19, Jean-Antoine Ribeil, MD, PhD20,21,22,23*, Carmen Garrido, PhD5,6,24*, Genevieve Courtois, PhD25*, Narla Mohandas, D.Sc.26 and Olivier Hermine9,10,12,27*

1Laboratoire INSERM, unité mixte de recherche 1163, centre national de la recherche scientifique (CNRS) e´quipe de recherche labellisée 8254, 24 Boulevard de Montparnasse, 75015 Paris, France, Paris, France
2Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Assistance publique – Hôpitaux de Paris, Hôpital Necker, 24 Boulevard de Montparnasse, 75015 Paris, France, Paris, France
3Laboratory of Excellence GR-Ex, 75015 Paris, France, Paris, France
4Laboratoire d’Excellence GR-Ex, PARIS, France
5INSERM, unité mixte de recherche 866, Equipe labellisée Ligue contre le Cancer and Association pour la Recherche contre le Cancer, and Laboratoire d’Excellence Lipoprotéines et santé (LipSTIC), 21033 Dijon, France, Dijon, France
6University of Burgundy, Faculty of Medicine and Pharmacy, 7 boulevard Jeanne d’Arc, 21033 Dijon, France, Dijon, France
7INSERM, unité mixte de recherche 866, Equipe labellisée Ligue contre le Cancer and Association pour la Recherche contre le Cancer, and Laboratoire d’Excellence Lipoprotéines et santé (LipSTIC), 21033 Dijon, France., Dijon, France
8INSTITUT COCHIN, INSERM U1016, PARIS, France
9Imagine Institute, Sorbonne Paris Cité, Paris Descartes University, Paris, France
10Department of Hematology, Necker Children's hospital, APHP, Paris, France
11Imagine Institute, INSERM UMR 1163, CNRS ERL 8654, Paris, France
12Centre de référence des déficits immunitaires héréditaires (CEREDIH), Necker Children's hospital, APHP, Paris, France
13Service de médecine interne, faculté de médecine Paris Descartes, Sorbonne Paris-Cité et Assistance publique-hôpitaux de Paris, hôpital européen Georges Pompidou, 20, rue Leblanc, 75015 Paris, France, Paris, France
14Centre national de référence des syndromes drépanocytaires majeurs, Paris, France
15Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Assistance publique – Hoˆpitaux de Paris, Hoˆ pital Necker, 24 Boulevard de Montparnasse, 75015 Paris, France., Paris, France
16Laboratoire INSERM, unité mixte de recherche 1163, centre national de la recherche scientifique (CNRS) équipe de recherche labellisée 8254, 24 Boulevard de Montparnasse, 75015 Paris, France., Paris, France
17Laboratoire d'excellence Gr-Ex, Paris, France
18Plateforme de Protéomique 3p5, Université Paris Descartes, PARIS, France
19New York Blood Center, New York, NY
20Hôpital Universitaire Necker -Enfants Malades, Paris, France
21Biotherapy Department, Hopital Universitaire Necker-Enfants Malades, Paris, France
22Paris Descartes Sorbonne Paris Cite University, Paris, France
23Laboratory of Excellence, GR-ex, Paris, France
24Centre anticancéreux George François Leclerc, 1 rue professeur Marion, 21079 Dijon, France, Dijon, France
25Laboratoire Inserm UMR 1163, CNRS ERL 8254, institut Imagine, hôpital Necker, laboratoire d’excellence sur le globule rouge (GR-Ex), Paris, France
26Red Cell Physiology Laboratory, New York Blood Center, New York, NY
27Institut Imagine, INSERM 1163/CNRS ERL 8254, Paris, France

Stefan Radtke, PhD1,2,3*, Kevin G Haworth, PhD1* and Hans-Peter Kiem, MD1,4,5

1Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
2Institute for Transfusion Medicine,, University of Duisburg-Essen, University Hospital Essen, Essen, Germany
3German Cancer Consortium, Heidelberg, Germany
4University of Washington, Seattle, WA
5Department of Pathology, University of Washington School of Medicine, Seattle

Daniel Ewerth1*, Stefanie Kreutmair1*, Birgit Kügelgen1*, Dagmar Wider1*, Julia Felthaus1*, Julia Schüler, DVM, PhD2*, Andrea Schmidts1*, Justus Duyster, MD, PhD1*, Anna Lena Illert1*, Monika Engelhardt3 and Ralph Wäsch, MD, PhD4*

1Dept. of Hematology, Oncology and Stem Cell Transplantation, University Medical Center, Freiburg, Germany
2Department Head In Vivo Tumorbiology, Oncotest GmbH, Freiburg, Germany
3Department of Internal Medicine I, Freiburg, Germany
4Department of Hematology, Oncology and Stem Cell Transplantation, University of Freiburg Medical Center, Freiburg, Germany

Yorky Tsin Sik Wong, BSc1*, Kam Tong Leung, PhD1*, Karen Li, PhD1*, Kathy Yuen Yee Chan, PhD1*, Xiao-Bing Zhang, PhD2*, Tak Yeung Leung, MD3*, Kam Sze Tsang, PhD4*, Ting Fan Leung, MD1*, Pak Cheung Ng, MD, FRCPCH1* and Chi Kong Li, MD1

1Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong, Hong Kong
2Department of Medicine, Loma Linda University, Loma Linda, CA
3Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong, Hong Kong
4Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children’s Research Hospital, Memphis, TN

Jenna M. Frame, Ph.D.1, Katherine H. Fegan, MS1*, Seana C. Catherman, BS1*, Joanna Tober, Ph.D.2*, Anne D. Koniski, MS1*, Kathleen E McGrath, PhD1 and James Palis, MD1

1Department of Pediatrics, University of Rochester Medical Center, Rochester, NY
2Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA

Erica Bresciani, PhD1*, Blake Carrington2*, Erika Mijin Kwon, PhD1*, Marypat Jones2*, Stephen Wincovitch2*, Raman B. Sood, PhD1* and Paul P. Liu, MD, PhD1

1Translational and Functional Genomics Branch, NIH, NHGRI, Bethesda, MD
2NIH, NHGRI, Bethesda, MD

Christopher W Dougher1*, Alexander Buffone Jr., PhD2*, Mehrab Nasirikenari, PhD2* and Joseph T. Lau, PhD2*

1Department of Immunology, Roswell Park Cancer Institute, Buffalo, NY
2Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, NY

Sasan Zandi, MD PhD1, John E. Dick, PhD1,2, Faiyaz Notta3* and Naoya Takayama4*

1Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
2Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
3OICR, Toronto, ON, Canada
4UHN, toronto, Canada

Racheal L Cooper, MS1*, Allison F. Scalora, MS2*, Elaine Wang, MD2*, John M. McCarty, MD2, Jennifer Anderson, RN2*, Catherine H. Roberts, PhD2*, Troy Lund, MD, PhD3, Amir A. Toor, MD2* and Angela Reynolds, PhD1*

1Department of Mathematics and Applied Mathematics, Virginia Commonwealth University, Richmond, VA
2Massey Cancer Center Bone Marrow Transplant Program, Virginia Commonwealth University, Richmond, VA
3Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN

*signifies non-member of ASH