Murakami Shohei, PhD^1*, Masayuki Yamamoto, MD, PhD² and Hozumi Motohashi, MD, PhD^1*

¹Institute of Development, Aging and Cancer, Tohoku University, Sendai, Japan
²Department of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Japan

Karen K Vo, BS^1,2, Danuta Jadwiga Jarocha, PhD^1*, Randolph B Lyde Jr., BS^1,2, Spencer Sullivan, MD^3*, Deborah French, PhD^4* and Mortimer Poncz, MD^4,5

¹Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA
²Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, PA
³Division of Hematology, University of Mississippi Medical Center, Jackson, MS
⁴Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA
⁵Department of Pediatrics, University of Pennsylvania, Philadelphia, PA

Qingsong Qiu, PhD candidate^1*, Ping Liu, MD^1*, Xuemei Zhao, BS^1*, Chun Zhang, MS^1*, Donghe Li, BS^1*, Ruihong Zhang, BS^1* and Ruibao Ren, MD, PhD^1,2

¹State Key Laboratory of Medical Genomics and Shanghai Institute of Hematology, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
²Department of Biology, Brandeis University, Waltham, MA

Seonmi Park^1*, Andreia Gianotti-Sommer^1*, David H.K. Chui, MD², Maria Stella Figueiredo, MD, PhD^3*, Abdulrahman Alsultan, MD^4*, Amein Al-Ali^5*, Martin H Steinberg, Professor, of, Medicine⁶, George J. Murphy, Ph.D^7* and Gustavo Mostoslavsky^8*

¹Center for Regenerative Medicine (CReM), Boston University, Boston, MA
²Department of Medicine, Boston University School of Medicine, Boston, MA
³Hematology and Blood Transfusion Division, Escola Paulista de Medicina / Universidade Federal de Sao Paulo, Sao Paulo SP, Brazil
⁴Sickle Cell Disease Research Center and Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Saudi Arabia
⁵Center for Research & Medical Consultation, University of Dammam, Dammam, Saudi Arabia
⁶Department of Medicine/Division of Hematology and Oncology, Boston University School of Medicine, Boston, MA
⁷Department of Medicine, Center for Regenerative Medicine (CReM), Boston University, Boston, MA
⁸Department of Medicine, Center for Regenerative Medicine (CReM), Boston University School of Medicine, Boston, MA

Takashi Higo, MD^1*, Junji Koya, MD, PhD^1*, Yoshiki Sumitomo^1,2*, Takako Tsuruta-Kishino, PhD^1*, Keisuke Kataoka, MD, Ph.D.^3*, Tomohiko Sato, MD, PhD^1* and Mineo Kurokawa, MD⁴

¹Department of Hematology & Oncology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan
²Oncology Research Laboratories, Kyowa Hakko Kirin Co., Ltd, tokyo, Japan
³Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
⁴Department of Hematology and Oncology, The University of Tokyo Graduate School of Medicine, Tokyo, Japan

Yukiko Doi, MD^1*, Takafumi Yokota, MD, PhD¹, Tomohiko Ishibashi, MD^1*, Yusuke Satoh, MD, PhD², Michiko Ichii, MD, PhD^1*, Akira Tanimura, MD, PhD^1*, Sachiko Ezoe, MD, PhD^1*, Hirohiko Shibayama, MD, PhD¹, Kenji Oritani, MD, PhD^1* and Yuzuru Kanakura, MD, PhD¹

¹Department of Hematology and Oncology, Osaka University Graduate School of Medicine, Suita, Japan
²Department of Lifestyle Studies, Kobe Shoin Women's University, Kobe, Japan

Tiago R Matos, MD, MSc^1,2*, Hongye Liu^1*, Masahiro Hirakawa, MD, PhD^3*, Ana Cristina Alho, MD^4,5* and Jerome Ritz, MD^4,6

¹Division of Hematologic Malignancies and Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
²Faculdade de Medicina da Universidade de Lisboa, Instituto de Medicina Molecular, Lisbon, Portugal
³Division of Hematologic Malignancies, Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA
⁴Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Boston, MA
⁵Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal
⁶Harvard Medical School, Boston, MA

Frederik Otzen Bagger, PhD^1,2,3,4,5*, Damir Sasivarevic^6*, Sina Hadi Sohi^6*, Linea Gøricke Laursen^1,2,3*, Sachin Pundhir, PhD^1,2,3,4*, Ole Winther, PhD^7*, Nicolas Rapin, PhD^1,2,3,4* and Bo T Porse, PhD^1,2,3*

¹Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark
²Danish Stem Cell Centre (DanStem), Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
³The Finsen Laboratory, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
⁴Bioinformatics Centre, Department of Biology, Faculty of Natural Sciences, University of Copenhagen, Copenhagen, Denmark
⁵Current address: Dept. of haematology, Current address: University of Cambridge and EMBL-EBI, Cambridge, England
⁶Technical University of Denmark, Kgs. Lyngby, Denmark
⁷DTU Compute, Technical University of Denmark, Kgs. Lyngby, Denmark

Canxin Xu, MD, PhD^1,2*, Kyunghee Choi, PhD^1,2, Tae-Jin Lee^1* and Nagisa Sakurai^1*

¹Pathology&Immunology, Washington University in St Louis, St Louis, MO
²Developmental, Regenerative and Stem Cell Biology Program, Washington University in St Louis, St Louis, MO

Sasan Zandi, MD PhD¹, Faiyaz Notta^2,3*, John E. Dick, PhD¹, Naoya Takayama^4*, Stephanie M Dobson, MSc^1*, Olga I Gan, PhD^5*, Gavin Wilson^6*, Kerstin Kaufmann^7*, Jessica McLeod^7*, Elisa Laurenti, PhD^8*, Cyrille Dunant^9*, Mcpherson John^6*, Lincoln Stein^6* and Yigal Dror, MD, FRCP(C)¹⁰

¹Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
²Ontario Institute For Cancer Research, Toronto, ON, Canada
³OICR, Toronto, ON, Canada
⁴UHN, Tokyo, Canada
⁵Department of Molecular Genetics, University of Toronto, Princess Margaret Cancer Centre, University Health Network, TORONTO, ON, Canada
⁶OICR, TORONTO, Canada
⁷UHN, TORONTO, Canada
⁸Cambridge Stem Cell Institute, Department of Haematology, University of Cambridge, Cambridge, England
⁹EPFL, Lausanne, Switzerland
¹⁰Marrow Failure and Myelodysplasia Program, Division of Hematology/Oncology, Department of Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada

Heather A. O'Leary, Ph.D.¹, Thomas McNamara^2* and Hal E. Broxmeyer, Ph.D.³

¹Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN
²Indiana University School of Medicine/ Trinity College, Indianapolis, IN
³Department of Microbiology/Immunology, Indiana University School of Medicine, Indianapolis, IN

Kohta Miyawaki, MD^1*, Hiromi Iwasaki, MD, PhD² and Koichi Akashi, MD, PhD^1*

¹Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
²Center for Cellular and Molecular Medicine, Kyushu University Hospital, Fukuoka, Japan

Saritha D'Souza, PhD^1*, John Maufort, PhD^1*, Akhilesh Kumar, PhD^1*, James Thomson, D.V.M., PhD^2* and Igor Slukvin, MD, PhD^1,3

¹Wisconsin National Primate Research Center, University of Wisconsin, Madison, WI
²Morgridge Institute for Research, Madison, WI
³Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI

Raedun Clarke, PhD^1*, William Kim, PhD^2*, Brian Groff, BS^2*, Ramzey Abujarour, PhD^1*, Megan Robinson, BS^1*, Xiaosong Huang, PhD^1*, Newsha Sahaf^2*, Sarah Raynel, MS^1*, Betsy Rezner, BS^1*, David Robbins, BS^1*, Lisa Guerrettaz, PhD^1*, Daniel Shoemaker, PhD^1* and Bahram Valamehr, PhD, MBA^2*

¹Fate Therapeutics, San Diego, CA
²Fate Therapeutics Inc, San Diego, CA

Yoshikazu Matsuoka, Ph.D.^*, Keisuke Sumide, Phar.B.^*, Hiroshi Kawamura, M.D.^*, Ryusuke Nakatsuka, Ph.D.^*, Tatsuya Fujioka, M.D., Ph.D.^*, Yutaka Sasaki, M.D., Ph.D.^* and Yoshiaki Sonoda, M.D., Ph.D.

Department of Stem Cell Biology and Regenerative Medicine, Kansai Medical University, Hirakata, Japan

Tonio Lang^*, Friederike Herbst, PhD^*, Elias Eckert^*, Peer Wünsche^*, Shayda Hemmati, PhD^*, Tim Kindinger^*, Nina Hofmann^*, Oksana Zavidij, PhD^*, Manfred Schmidt, PhD^*, Claudia Ball, PhD^* and Hanno Glimm, MD

Department of Translational Oncology, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Heidelberg, Germany

Yan Xiu, MD PhD^* and Chen Zhao, MD PhD

University of Iowa, Iowa City, IA

Flavia Guillem, PhD^1,2,3*, Michael Dussiot, PhD^4*, Sebastien Causse, PhD^5,6*, Guillaume Marcion^7*, Emilie-Fleur Gautier, PhD^4,8*, Julien Rossignol, MD^9,10,11,12*, Jean benoit Arlet, MD, PhD^13,14*, Mathilde Lamarque, MD^3,15,16*, Patrick Mayeux, PhD^8,17,18, Frederique Verdier, PhD^4,8*, Xiuli An, MD, PhD¹⁹, Jean-Antoine Ribeil, MD, PhD^20,21,22,23*, Carmen Garrido, PhD^5,6,24*, Genevieve Courtois, PhD^25*, Narla Mohandas, D.Sc.²⁶ and Olivier Hermine^9,10,12,27*

¹Laboratoire INSERM, unité mixte de recherche 1163, centre national de la recherche scientifique (CNRS) e´quipe de recherche labellisée 8254, 24 Boulevard de Montparnasse, 75015 Paris, France, Paris, France
²Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Assistance publique – Hôpitaux de Paris, Hôpital Necker, 24 Boulevard de Montparnasse, 75015 Paris, France, Paris, France
³Laboratory of Excellence GR-Ex, 75015 Paris, France, Paris, France
⁴Laboratoire d’Excellence GR-Ex, PARIS, France
⁵INSERM, unité mixte de recherche 866, Equipe labellisée Ligue contre le Cancer and Association pour la Recherche contre le Cancer, and Laboratoire d’Excellence Lipoprotéines et santé (LipSTIC), 21033 Dijon, France, Dijon, France
⁶University of Burgundy, Faculty of Medicine and Pharmacy, 7 boulevard Jeanne d’Arc, 21033 Dijon, France, Dijon, France
⁷INSERM, unité mixte de recherche 866, Equipe labellisée Ligue contre le Cancer and Association pour la Recherche contre le Cancer, and Laboratoire d’Excellence Lipoprotéines et santé (LipSTIC), 21033 Dijon, France., Dijon, France
⁸INSTITUT COCHIN, INSERM U1016, PARIS, France
⁹Imagine Institute, Sorbonne Paris Cité, Paris Descartes University, Paris, France
¹⁰Department of Hematology, Necker Children's hospital, APHP, Paris, France
¹¹Imagine Institute, INSERM UMR 1163, CNRS ERL 8654, Paris, France
¹²Centre de référence des déficits immunitaires héréditaires (CEREDIH), Necker Children's hospital, APHP, Paris, France
¹³Service de médecine interne, faculté de médecine Paris Descartes, Sorbonne Paris-Cité et Assistance publique-hôpitaux de Paris, hôpital européen Georges Pompidou, 20, rue Leblanc, 75015 Paris, France, Paris, France
¹⁴Centre national de référence des syndromes drépanocytaires majeurs, Paris, France
¹⁵Paris Descartes-Sorbonne Paris Cité University, Imagine Institute, Assistance publique – Hoˆpitaux de Paris, Hoˆ pital Necker, 24 Boulevard de Montparnasse, 75015 Paris, France., Paris, France
¹⁶Laboratoire INSERM, unité mixte de recherche 1163, centre national de la recherche scientifique (CNRS) équipe de recherche labellisée 8254, 24 Boulevard de Montparnasse, 75015 Paris, France., Paris, France
¹⁷Laboratoire d'excellence Gr-Ex, Paris, France
¹⁸Plateforme de Protéomique 3p5, Université Paris Descartes, PARIS, France
¹⁹New York Blood Center, New York, NY
²⁰Hôpital Universitaire Necker -Enfants Malades, Paris, France
²¹Biotherapy Department, Hopital Universitaire Necker-Enfants Malades, Paris, France
²²Paris Descartes Sorbonne Paris Cite University, Paris, France
²³Laboratory of Excellence, GR-ex, Paris, France
²⁴Centre anticancéreux George François Leclerc, 1 rue professeur Marion, 21079 Dijon, France, Dijon, France
²⁵Laboratoire Inserm UMR 1163, CNRS ERL 8254, institut Imagine, hôpital Necker, laboratoire d’excellence sur le globule rouge (GR-Ex), Paris, France
²⁶Red Cell Physiology Laboratory, New York Blood Center, New York, NY
²⁷Institut Imagine, INSERM 1163/CNRS ERL 8254, Paris, France

Stefan Radtke, PhD^1,2,3*, Kevin G Haworth, PhD^1* and Hans-Peter Kiem, MD^1,4,5

¹Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
²Institute for Transfusion Medicine,, University of Duisburg-Essen, University Hospital Essen, Essen, Germany
³German Cancer Consortium, Heidelberg, Germany
⁴University of Washington, Seattle, WA
⁵Department of Pathology, University of Washington School of Medicine, Seattle

Daniel Ewerth^1*, Stefanie Kreutmair^1*, Birgit Kügelgen^1*, Dagmar Wider^1*, Julia Felthaus^1*, Julia Schüler, DVM, PhD^2*, Andrea Schmidts^1*, Justus Duyster, MD, PhD^1*, Anna Lena Illert^1*, Monika Engelhardt³ and Ralph Wäsch, MD, PhD^4*

¹Dept. of Hematology, Oncology and Stem Cell Transplantation, University Medical Center, Freiburg, Germany
²Department Head In Vivo Tumorbiology, Oncotest GmbH, Freiburg, Germany
³Department of Internal Medicine I, Freiburg, Germany
⁴Department of Hematology, Oncology and Stem Cell Transplantation, University of Freiburg Medical Center, Freiburg, Germany

Yorky Tsin Sik Wong, BSc^1*, Kam Tong Leung, PhD^1*, Karen Li, PhD^1*, Kathy Yuen Yee Chan, PhD^1*, Xiao-Bing Zhang, PhD^2*, Tak Yeung Leung, MD^3*, Kam Sze Tsang, PhD^4*, Ting Fan Leung, MD^1*, Pak Cheung Ng, MD, FRCPCH^1* and Chi Kong Li, MD¹

¹Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong, Hong Kong
²Department of Medicine, Loma Linda University, Loma Linda, CA
³Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong, Hong Kong
⁴Department of Bone Marrow Transplantation and Cellular Therapy, St. Jude Children’s Research Hospital, Memphis, TN

Jenna M. Frame, Ph.D.¹, Katherine H. Fegan, MS^1*, Seana C. Catherman, BS^1*, Joanna Tober, Ph.D.^2*, Anne D. Koniski, MS^1*, Kathleen E McGrath, PhD¹ and James Palis, MD¹

¹Department of Pediatrics, University of Rochester Medical Center, Rochester, NY
²Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA

Erica Bresciani, PhD^1*, Blake Carrington^2*, Erika Mijin Kwon, PhD^1*, Marypat Jones^2*, Stephen Wincovitch^2*, Raman B. Sood, PhD^1* and Paul P. Liu, MD, PhD¹

¹Translational and Functional Genomics Branch, NIH, NHGRI, Bethesda, MD
²NIH, NHGRI, Bethesda, MD

Christopher W Dougher^1*, Alexander Buffone Jr., PhD^2*, Mehrab Nasirikenari, PhD^2* and Joseph T. Lau, PhD^2*

¹Department of Immunology, Roswell Park Cancer Institute, Buffalo, NY
²Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, NY

Sasan Zandi, MD PhD¹, John E. Dick, PhD^1,2, Faiyaz Notta^3* and Naoya Takayama^4*

¹Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
²Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
³OICR, Toronto, ON, Canada
⁴UHN, toronto, Canada

Racheal L Cooper, MS^1*, Allison F. Scalora, MS^2*, Elaine Wang, MD^2*, John M. McCarty, MD², Jennifer Anderson, RN^2*, Catherine H. Roberts, PhD^2*, Troy Lund, MD, PhD³, Amir A. Toor, MD^2* and Angela Reynolds, PhD^1*

¹Department of Mathematics and Applied Mathematics, Virginia Commonwealth University, Richmond, VA
²Massey Cancer Center Bone Marrow Transplant Program, Virginia Commonwealth University, Richmond, VA
³Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN