Izabella Andrianova^1,2*, Vincent M Hayes, BS^3*, Daria Madeeva, MD^3*, Rustem I. Litvinov, PhD^2*, Douglas B. Cines, MD⁴, Mortimer Poncz, MD^3,5, John W. Weisel, PhD² and Lubica Rauova, MD, PhD^3,5

¹Institute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia
²Department of Cell and Developmental Biology, University of Pennsylvania, Philadelphia, PA
³Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA
⁴Department of Pathology and Laboratory Medicine, The University of Pennsylvania, Philadelphia, PA
⁵Department of Pediatrics, University of Pennsylvania, Philadelphia, PA

Noriyuki Takahashi^1*, Takayuki Saitoh, MD, PhD^1*, Nanami Gotoh^1*, Kei Kimura^1*, Yuko Kuroda^1*, Kie Nagai^1*, Tomomi Nagashima^1*, Tetsuhiro Kasamatsu^1*, Yusuke Minato, PhD^2*, Hiroaki Shimizu, M.D., PhD.^3*, Takuma Ishizaki^4*, Akihiko Yokohama, MD, PhD⁵, Makiko Takizawa, PhD, MD^4*, Hiromi Koiso^4*, Takeki Mitsui^4*, Norifumi Tsukamoto, MD, PhD⁴, Hiroshi Handa, MD, PhD^4* and Hirokazu Murakami, MD PhD⁶

¹Department of Laboratory Science, Gunma University Graduate School of Health Sciences, Gunma, Japan
²Department of Virology and Preventive Medicine, Gunma University, Gunma, Japan
³Oncology Center, Gunma University Hospital, Gunma, Japan
⁴Department of Medicine and Clinical Science, Gunma University Graduate School of Medicine, Gunma, Japan
⁵Division of Blood Transfusion Service, Gunma University Hospital, Gunma, Japan
⁶Graduate School of Health Sciences, Gunma University, Maebashi, Japan

Daniel W. Bougie, PhD, Julie A. Peterson, PhD, Mark Rasmussen^* and Richard H. Aster, MD

Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI

Natthapol Songdej, MD, MPH¹, Guangfen Mao, MD^2*, Lawrence E. Goldfinger, PhD^2* and Angara Koneti Rao, MD³

¹Department of Medicine, Temple University School of Medicine, Philadelphia, PA
²Sol Sherry Thrombosis Research Center, Temple University School of Medicine, Philadelphia, PA
³Sol Sherry Thrombosis Research Center and Department of Medicine, Temple University School of Medicine, Philadelphia, PA

Silvia Cantoni, MD^1*, Monica Carpenedo, MD^2*, Domenico Sica Lanfranco, MD^3*, Michele Nichelatti^4*, Massimo Milella, MD^5*, Angela Centroni, MD^3* and Roberto Cairoli, MD^6*

¹Department of Hematology, Niguarda Hospital, Milan, Italy
²Hematology and Transplant Unit, San Gerardo Hospital, Monza, Italy
³Department of Biochemistry, Niguarda Hospital, Milan, Italy
⁴Service of Biostatistics, Niguarda Ca’ Granda Hospital, Milan, Italy
⁵Nuclear Medicine Unit, Niguarda Hospital, Milan, Italy
⁶Division of Hematology, Niguarda Ca' Granda Hospital, Milan, Italy

Shugo Kowata, MD, PhD^1*, Ryo Togawa, MD^2*, Yoshiaki Okano, MD^1*, Sumio Isogai, PhD^3*, Jiro Hitomi, MD PhD^4*, Kazunori Murai, MD, PhD⁵, Shigeki Ito, MD, PhD⁶ and Yoji Ishida, M.D., Ph.D.⁷

¹Hematology / Oncology, Department of Internal Medicine, Iwate Medical University, School of Medicine, Morioka, Japan
²Hematology/ Oncology, Iwate Medical University School of Medicine, Morioka, Japan
³Anatomy and human Embryology, Iwate Medical University School of Medicine, Morioka, Japan
⁴Anatomy and Human Embryology, Iwate Medical University School of Medicine, Morioka, Japan
⁵Iwate Prefectural Central Hospital, Morioka, Japan
⁶Division of Clinical Oncology, Iwate Medical University, School of Medicine, Morioka, Japan
⁷Division of Hematology and Oncology, Department of Internal Medicine, Iwate Medical University School of Medicine, Morioka, Japan

Marc Michel, MD,^1,2*, Daniel Adoue, MD, PhD^3*, Stéphane Cheze, MD, PhD^4*, Paul Coppo, MD, PhD^5*, Soraya Leclerc-Teffahi, PhD^6*, Jerome Fernandes, MS^7* and Nathalie Texier, MS^7*

¹Internal Medicine, French referral center for adult's immune cytopenia, Henri Mondor Hospital, AP-HP, UPEC University, Créteil, France
²Hôpital Henri-Mondor, APHP, Créteil, France
³Internal Medicine, Hopital Purpan, Toulouse, France
⁴Institut d’Hématologie de Basse-Normandie, CHU Caen Hôpital Côte de Nacre, Caen, France
⁵Hematology, Saint-Antoine Hospital, Paris, France
⁶Novartis, Rueil-Malmaison, France
⁷Kappa Santé, Paris, France

Rick Kapur, MD, PhD^1*, Rukhsana Aslam, PhD^1*, Edwin R. Speck, BRT^1*, Michael Kim, BSc^1*, Anne Zufferey, PhD^1*, Li Guo, MD¹, George B. Segel, MD², Heyu Ni, MD, PhD³ and John W. Semple, PhD¹

¹St. Michael's Hospital, Toronto, ON, Canada
²University of Rochester, Rochester, NY
³Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada

Laurence A. Greenbaum, MD, PhD^1*, Yahsou Delmas, MD, PhD^2*, Fadi Fakhouri, MD, PhD^3*, John F. Kincaid, MD, MA^4*, Christoph Licht, MD, FRCP(C), FASN^5*, Enrico E. Minetti, MD^6*, Chris Mix, MD^7*, Francois Provôt, MD^8*, Eric Rondeau, MD, PhD^9*, Neil Sheerin, BSc, MBBS, MRCP, PhD, FRCP^10*, Jimmy Wang, PhD^7*, Laurent E. Weekers, MD^11* and Jan Menne, MD^12*

¹Emory University, Atlanta, GA
²CHU de Bordeaux, Bordeaux, France
³CHU de Nantes, Nantes, France
⁴Alexion Pharmaceuticals, Inc., Cheshire, CT
⁵Division of Nephrology, The Hospital for Sick Children, Toronto, ON, Canada
⁶Careggi University Hospital, Florence, Italy
⁷Alexion, Cheshire, CT
⁸CHU de Lille, Lille, France
⁹Hôpital Tenon & Université Paris VI, Paris, France
¹⁰Newcastle University, Newcastle upon Tyne, United Kingdom
¹¹Centre Hospitalier Universitaire, Liège, Belgium
¹²Klinik für Nieren- und Hochdruckerkrankungen, Hannover, Germany

Erin Elizabeth Roesch, MD¹ and Catherine Broome, MD²

¹Division of Hematology/Oncology, Medstar Georgetown University Hospital, Washington, DC
²Hematology/Oncology, MedStar Georgetown University Hospital, Washington, DC

Issaka Yougbare, PhD^1*, Tai Wei-she, Bsc^1*, Darko Zdravic, MSc^2*, Pingguo Chen, MD, PhD², Guangheng Zhu, MD^1*, Howard Leong-Poi, MD^3*, Qu Dawei, PhD^4*, X. Lisa Yu, MD^4*, S. Adamson Lee, PhD^5*, John Sled, PhD^6*, Freedman John, MD^7* and Heyu Ni, MD, PhD^8,9

¹Toronto Platelet Immunobiology Group, Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada
²Toronto Platelet Immunobiology Group, Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, Canadian Blood Services, Toronto St. Michael's Hospital, University of Toronto, Toronto, ON, Canada
³Division of Cardiology, Keenan Research Centre for Biomedical Science, St Michael’s Hospital and Institute of Medical Science, University of Toronto, Toronto, ON, Cape Verde
⁴Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Toronto, ON, Canada
⁵Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario, Canada. Departments of Obstetrics and Gynaecology, University of Toronto, Toronto, ON, Canada
⁶Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Departments of Medical Biophysics, University of Toronto, Toronto, ON, Burma
⁷Toronto Platelet Immunobiology Group, Department of Laboratory Medicine, Keenan Research Centre for Biomedical Science, Toronto St. Michael's Hospital, Department of Physiology and Medicine, University of Toronto, Toronto, ON, Canada
⁸Canadian Blood Services, Canada, St. Michael's Hospital, Toronto, ON, Canada
⁹Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada

Niklas Boknäs, MD.^1*, Sofia Ramström, Associate professor^2*, Lars Faxälv^2* and Tomas L Lindahl, Professor, MD²

¹Department of hematology, Linköping University, Linköping, Sweden
²Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden

Jessica A. Reese, MS^1,2*, David R. Deschamps, MD^1*, Jennifer J. McIntosh, DO^1*, Eric J. Knudtson, MD^1*, Jennifer D. Peck, PhD^2*, Sara K. Vesely, PhD² and James N. George, MD^1,2

¹Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, OK
²Department of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK

Alberto Vazquez Mellado, MD, Olga Graciela Cantu-Rodriguez, MD^*, Myrna Pequeño-Luévano, MD^*, Laura Villarreal-Martínez, MD^*, José Carlos Jaime-Pérez, MD^*, Andres Gomez-De-Leon, MD^*, Oscar Gonzalez-Llano, MD, PhD^*, Perla Colunga-Pedraza, MD^*, Guillermo Sotomayor-Duque^* and David Gomez-Almaguer, MD^*

Hematology, Hospital Universitario Jose Eleuterio Gonzalez, Monterrey, Mexico

Matthew E. Lebow, BA, NREMT-P^1*, Michael DeSarno, MS^2*, Damon Eugene Houghton, MD, BS^3*, John P. Winters III, MD⁴, Samuel A. Merrill, MD, PhD⁵, George F. Atweh, M.D.¹ and Neil A Zakai, MD, MSc⁶

¹University of Vermont, Burlington, VT
²University of Vermont, Burlington
³University of North Carolina, Chapel Hill, NC
⁴St. Charles Health System, Bend, OR
⁵John Hopkins University, Baltimore, MD
⁶Medicine, University of Vermont, Colchester, VT

Monica Escorcio-Correia, PhD^1*, Andrew Provan, MD² and Daniel J Pennington, PhD^1*

¹Blizard Institute, Centre for Immunobiology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
²Haematology Department, Barts and the London School of Medicine and Dentistry, London, United Kingdom

Nicole De Simone, MD, MPH^1*, Ravi Sarode, MD², Sean Yates, MD^2*, Karen Matevosyan, MD³, Manasa Reddy, MD^1*, Chakri Gavva, MD^4*, Ayesha Zia, MD⁵ and Yu-Min Shen, MD⁶

¹UT Southwestern Medical Center at Dallas, Dallas, TX
²Transfusion Medicine, University of Texas Southwestern Medical Center, Dallas, TX
³UT Southwestern Medical Center, Dallas, TX
⁴UT Southwestern Medical School, Dallas, TX
⁵Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX
⁶Division of Hematology/Oncology, UT Southwestern Medical Center at Dallas, Dallas, TX

Gail Rock, PhD, MD¹, Steven Weger, MD^2*, Hana Abouhadjar, MD^3*, David Barth, MD, FRCPC^4*, William Clark, MD^5*, Paul R. Yenson, MD, FRCPC⁶ and Stephen Ronan Foley, MD, FRCPC⁷

¹The Canadian Apheresis Group, Ottawa, ON, Canada
²National Viral Lab, Winnipeg, Canada
³Canadian Apheresis Group, Ottawa, Canada
⁴University Health Network, Department of Pathobiology and Laboratory Medicine, Toronto, ON, Canada
⁵Kidney Clinical Research Unit, London Health Sciences Centre, London, ON, Canada
⁶Division of Hematology, Department of Medicine, Vancouver General Hospital, Vancouver, BC, Canada
⁷Hamilton Health Sciences, Hamilton, ON, Canada

Bethany T Samuelson, MD¹, Meredith Holmes, PharmD^2*, Andrew White, MD^3*, Emily Glynn, MD^4*, Daniel B Martin, MD^1*, David Garcia, MD⁵, Janet Kelly, PharmD^6* and Ann Kathryn Wittkowsky, PharmD^5*

¹Department of Medicine, Division of Hematology, University of Washington, Seattle, WA
²Department of Pharmacy, University of Washington, Seattle, WA
³Department of Medicine, University of Washington, Seattle, WA
⁴Department of Pathology, University of Washington, Seattle, WA
⁵University of Washington, Seattle, WA
⁶Department of Pharmacy, University of Washington, Seattle

Tomás José González-López, MD^1*, María Teresa Alvarez-Roman, MD^2*, Cristina Pascual, MD^3*, Blanca Sánchez-González, MD^4*, Fernando Fernández-Fuentes, MD^5*, Gloria Pérez-Rus, MD^6*, José Angel Hernández-Rivas, MD^7*, Silvia Bernat, MD^8*, Montserrat Cortés, MD^9*, José María Bastida, MD^10*, Violeta Martínez-Robles, MD^11*, Angeles Fernández-Rodríguez, MD^12*, Pavel Olivera, MD^13*, Estefanía Bolaños, MD^14*, Rafael Alonso, MD^15*, Laura Entrena, MD^16*, Marta Gómez-Nuñez, MD^17*, Nuria Bermejo, MD^18*, María Paz Martínez-Badas^19*, María Jesús Peñarrubia, MD^20*, Arancha Alonso, MD^21*, Inmaculada Soto, MD^12*, María Yera Cobo, MD^22*, Alberto Casaus, MD^23*, Isabel Caparrós, MD^24*, Marí­a Perera, MD^25*, Reyes Jiménez Bárcenas, MD^26*, Cecilia Heras, MD^7*, María Calbacho, MD^27*, Maria Tenorio, MD^28*, Armando Luaña, MD^29*, Elsa Lopez-Ansoar, MD^30*, Gerardo Hermida, MD^1*, Javier García-Frade, MD^31*, José Ramón González-Porras, MD^32* and Miguel A. Sanz, MD, PhD³³

¹Department of Hematology, Hospital Universitario de Burgos, Burgos, Spain
²Department of Hematology, Hospital Universitario La Paz, Madrid, Spain
³Hematology, Hospital General Universitario Gregorio Marañón, Madrid, Spain
⁴Department of Hematology, Hospital del Mar, Barcelona, Spain
⁵Department of Hematology, Hospital Universitario Insular de Gran Canaria, Las Palmas de Gran Canaria, Spain
⁶Department of Hematology, Hospital General Universitario Gregorio Marañón, Madrid, Spain
⁷Department of Hematology, Hospital Infanta Leonor, Madrid, Spain
⁸Hospital de La Plana, Department of Hematology, Castellón, Spain
⁹Department of Hematology, Fundació Hospital Asil de Granollers, Barcelona, Spain
¹⁰Hospital Universitario de Salamanca, Salamanca, Spain
¹¹Department of Hematology, Hospital de León, León, Spain
¹²Department of Hematology, Hospital Universitario Central de Asturias, Oviedo (Asturias), Spain
¹³Department of Hematology, Hospital Universitario Valle Hebrón, Barcelona, Spain
¹⁴Department of Hematology, Hospital Clínico San Carlos, Madrid, Spain
¹⁵Department of Hematology, Hospital Universitario Doce de Octubre, Madrid, Spain
¹⁶Hematology Department, Hospital Virgen de las Nieves, Granada, Spain
¹⁷Department of Hematology, Parc Sanitari Taulí, Sabadell (Barcelona), Spain
¹⁸Department of Hematology, Hospital San Pedro de Alcántara, Cáceres, Spain
¹⁹Department of Hematology, Hospital de Avila, Avila, Spain
²⁰Department of Hematology, Hospital Clínico de Valladolid, Valladolid, Spain
²¹Department of Hematology, Hospital Universitario Quirón Madrid, Madrid, Spain
²²Department of Hematology, Hospital Universitario Puerta del Mar, Cádiz, Spain
²³Department of Hematology, Hospital Punta de Europa, Algeciras (Cádiz), Spain
²⁴Department of Hematology, Hospital Clínico de Málaga, Málaga, Spain
²⁵Department of Hematology, Hospital Universitario de Gran Canaria Doctor Negrín, Las Palmas de Gran Canaria, Spain
²⁶Department of Hematology, Hospital Universitario Virgen del Rocío, Sevilla, Spain
²⁷Hospital Universitario Ramon y Cajal, Madrid, Spain
²⁸Department of Hematology, Hospital Universitario Ramón y Cajal, Madrid, Spain
²⁹Hematology Department, Hospital Arnau de Vilanova, Lérida, Spain
³⁰Hematology Department, Complejo Hospitalario Universitario de Ourense, Orense, Spain
³¹Department of Hematology, Hospital Universitario Río Hortega, Valladolid, Spain
³²Department of Hematology, Hospital Clínico de Salamanca, Salamanca, Spain
³³Servicio de Hematologia, Hospital Univ. La Fe, Valencia, Spain