Ali T Taher¹, M Domenica Cappellini², Yesim Aydinok³, John B. Porter^4*, Zeynep Karakas^5*, Vip Viprakasit⁶, Noppadol Siritanaratkul⁶, Antonis Kattamis⁷, Candace Wang^8*, Zewen Zhu^8*, Victor Joaquin^8*, Marie José Uwamahoro^9* and Yong-Rong Lai^10*

¹American University of Beirut Medical Center, Beirut, Lebanon
²Universitá di Milano, Ca Granda Foundation IRCCS, Milan, Italy
³Ege University Hospital, Izmir, Turkey
⁴University College London, London, United Kingdom
⁵Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey
⁶Department of Pediatrics and Internal Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
⁷First Dept of Pediatrics, University of Athens, Athens, Greece
⁸Novartis Pharmaceuticals, East Hanover, NJ
⁹Novartis Pharma AG, Basel, Switzerland
¹⁰The First Affiliated Hospital of Guangxi Medical University, Nanning, China

Alessia Pepe^1*, Antonella Meloni^1*, Alessandra Briatico Vangosa^2*, Fabrizia Terrazzino^3*, Maria Giovanna Neri^1*, Domenico Maddaloni^4*, Gaetano Roccamo^5*, Sabrina Armari^6*, Aurelio Maggio, MD⁷, Cristina Salvatori^8*, Vincenzo Positano^1* and Paolo Ricchi^9*

¹CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy
²Institute of Radiology, “G. D’Annunzio” University, Chieti, Italy
³Unità Operativa Complessa Radiologia, “ARNAS” Civico, Palermo, Italy
⁴Unità Operativa Complessa di Pediatria, Ospedale "Engles Profili", Fabriano, Italy
⁵Unità di Prevenzione e Cura delle Mictrocitemie, Ospedale "Civile", S. Agata di Militello (ME), Italy
⁶Reparto di Pediatria, Azienda Ospedaliera di Legnago, Legnago (VR), Italy
⁷Dept. of Hematology, Hospital 'V. Cervello', Palermo, Italy
⁸Unità Operativa Sistemi Informatici, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy
⁹Unità Operativa Semplice Dipartimentale Malattie Rare del Globulo Rosso, Azienda Ospedaliera di Rilievo Nazionale, Napoli, Italy

Dudley J Pennell^1*, John B Porter^2*, Antonio Piga, MD³, Jackie Han^4*, Alexander Vorog^4* and Yesim Aydinok⁵

¹Cardiovascular Biomedical Research Unit, Royal Brompton Hospital, London, United Kingdom
²University College London, London, United Kingdom
³University of Turin, Turin, Italy
⁴Novartis Pharmaceuticals, East Hanover, NJ
⁵Ege University Hospital, Izmir, Turkey

M Domenica Cappellini¹, Mohamed Bejaoui^2*, Silverio Perrotta, MD^3*, Leyla Agaoglu^4*, Antonis Kattamis⁵, Jackie Han^6*, Ali El-Ali^7* and John B Porter^8*

¹Universitá di Milano, Ca Granda Foundation IRCCS, Milan, Italy
²Centre National de Greffe de Moelle Osseuse, Bab Saadoun, Tunis, Tunisia
³Second University of Naples, Naples, Italy
⁴Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey
⁵First Department of Pediatrics, University of Athens, Athens, Greece
⁶Novartis Pharmaceuticals, East Hanover, NJ
⁷Novartis Pharma AG, Basel, Switzerland
⁸University College London, London, United Kingdom

Ersi Voskaridou^1*, Dimitrios Christoulas^2*, Maria Dimopoulou^1*, Konstantina Repa^1*, Maroussa Douskou^3* and Evangelos Terpos⁴

¹Thalassemia Center, Laikon General Hospital, Athens, Greece
²Department of Hematology, 251 General Air Force Hospital, Athens, Greece
³Bioiatriki Medical Center, Athens, Greece
⁴Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece

Hala Mounir Mohamed Moustafa Agha, MD^1*, Antoine AbdelMassih, Msc^2*, Mohamed Youssef Abd El Rahman, MD^1*, Ornella Milanesi,, MD^3*, Biagio Castaldi, MD^4*, Giulia Geranio, MD^5*, Ludovica Frizziero, MD^6*, Giuseppe Basso, MD^7*, Maria Caterina Putti, MD^8,9*, Ahmed Essam, Msc^10*, Reem Esmail, MD^2*, Ghada El-Kamah, MD^11*, Mona Hamdy, MD^2*, Heba El Baz, MD^2*, Noha El Behary, MD^10*, Carol Hanna^12*, Hassan El Tagy^13*, Mary Atef Mishriky^13*, Mirna Mamdouh^13*, Hossam Khalifa^13* and Soheir Adam, MD/Assistant Professor¹⁴

¹Pediatric Cardiology, Cairo University Specialized Pediatric Hospital, Cairo, Egypt
²Cairo University Specialized Pediatric Hospital, Cairo, Egypt
³Department of women and child health , padova university, padova, Italy
⁴Pediatric cardiology unit, , Department of women and child health , padova university, padova, Italy
⁵Department of women and child health (well being), Padova university, padova, Italy
⁶Clinica di Emato-Oncologia Pediatrica, Azienda Ospedaliero-Universitaria di Padova, Padova, Italy
⁷Laboratory of Haematology and Oncology, Department of Pediatrics, University of Padua, Padua, Italy
⁸Department of Women’s and Children’s Health, Laboratory of Oncohematology, University of Padua, Padua, Italy
⁹Department of Women’s and Chidren’s Health, University of Padua, Padua, Italy
¹⁰Department of Diagnostic Radiology, Cairo University, Cairo, Egypt
¹¹Genetics department,, National Research center of Egypt, Cairo, Egypt
¹²Cairo university, Cairo, Egypt
¹³Cairo University, Cairo, Egypt
¹⁴Department of Medicine, Duke University Medical Center, Durham, NC

Alessia Pepe^1*, Tommaso Casini^2*, Liana Cuccia^3*, Francesco Sorrentino^4*, Rosamaria Rosso^5*, Paolo Ricchi^6*, Aurelio Maggio⁷, Maria Giovanna Neri^1*, Maria Chiara Resta^8*, Valentina Vinci^9*, Vincenzo Positano^1* and Antonella Meloni^1*

¹CMR Unit, Fondazione G. Monasterio CNR-Regione Toscana, Pisa, Italy
²Centro Talassemie ed Emoglobinopatie, Ospedale Meyer, Firenze, Italy
³Unità Operativa Complessa Ematologia con Talassemia, ARNAS Civico, Palermo, Italy
⁴U.O.S. Dipartimentale - DH Talassemici, Ospedale, Roma, Italy
⁵U.O. Talassemie ed Emoglobinopatie, Ospedale "Ferrarotto" - Azienda Ospedaliero-Universitaria Policlinico "Vittorio Emanuele", Catania, Italy
⁶Unità Operativa Semplice Dipartimentale Malattie Rare del Globulo Rosso, Azienda Ospedaliera di Rilievo Nazionale, Napoli, Italy
⁷Ematologia II con Talassemia, Ospedale, Palermo, Italy
⁸Struttura Complessa di Radiologia, Ospedale "SS. Annunziata" ASL Taranto, Taranto, Italy
⁹Istituto di Radiologia, Az. Osp. "Garibaldi" - Presidio Ospedaliero Nesima, Catania, Italy

Natália Oliveira Mota, Master Student^1*, Elza Miyuki Kimura, B.Sc.^2*, Roberta Dorta Ferreira^1*, Dulcineia Albuquerque, PhD^3*, Daniela Maria Ribeiro^1*, Magnun Santos^1*, Fernando F Costa, M.D., Ph.D.³ and Maria Fatima Sonati, PhD^1*

¹Department of Clinical Pathology, University of Campinas, Campinas, Brazil
²Department of Clinical Pathology, University of Campinas, Campinas, SP, Brazil
³Hematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil