Jason H. Mendler, MD, PhD¹, Marlene Balys^1*, Umayal Sivagnanalingam^1*, Allison Eberhardt^1*, Korinne Thorne^1*, Tzu-Chieh Ho, PhD^1*, Mark W. LaMere, BA^1*, Samuel Moore^1*, Helene McMurray, PhD^1*, Jason R. Myers^1*, John M. Ashton, PhD^1*, Kristen O'Dwyer, MD^1*, Jane L. Liesveld, MD², Laura M. Calvi, MD¹ and Michael W. Becker, MD¹

¹James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY
²James P. Wilmot Cancer Institute, Department of Medicine, University of Rochester Medical Center, Rochester, NY

Terrence Neal Wong, MD PhD¹, Jeffery M. Klco, MD/PhD², Ryan Demeter^3*, Christopher A. Miller, PhD^4*, Allegra Petti, PhD^3*, Nichole Havey^5*, Robert Fulton, PhD^6*, Sharon Heath^7*, Elaine R Mardis, PhD^6*, Peter Westervelt, MD, PhD⁸, John F. DiPersio, MD, PhD⁹, Matthew J. Walter, MD¹⁰, John S. Welch, MD, PhD¹⁰, Timothy Graubert, MD¹¹, Richard K Wilson, PhD^6*, Timothy J. Ley, MD¹⁰ and Daniel C. Link, MD¹²

¹Division of Oncology, Department of Internal Medicine, Washington University in St. Louis School of Medicine, St. Louis, MO
²St Jude Children's Research Hospital, Memphis, TN
³The McDonnell Genome Institute, Washington University in St. Louis School of Medicine, Saint Louis, MO
⁴McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO
⁵Division of Oncology, Washington University in St. Louis School of Medicine, Saint Louis, MO
⁶Washington University School of Medicine, Saint Louis, MO
⁷Department of Medicine, Division of Oncology, Washington University in St. Louis, Saint Louis, MO
⁸Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO
⁹Department of Medicine, Division of Oncology, Washington University School of Medicine, Saint Louis, MO
¹⁰Division of Oncology, Washington University School of Medicine, St. Louis, MO
¹¹Medicine, Washington University, Saint Louis, MO
¹²Washington Univ. School of Medicine, Saint Louis, MO

Emilia L. Lim^1*, Diane L. Trinh, MSc^1*, Rhonda E. Ries, MA^2*, Yussanne Ma, PhD^3*, James Topham^1*, Maya D. Hughes, MD^4*, Erin Pleasance, PhD^1*, Andrew J. Mungall, PhD³, Richard Moore, PhD^1*, Yongjun Zhao, PhD^1*, Daniela S. Gerhard, PhD^5*, Vivian Oehler, MD⁶, E. Anders Kolb, MD⁷, Alan S. Gamis, MD, MPH⁸, Malcolm A. Smith, MD, PhD⁹, Todd A. Alonzo, PhD¹⁰, Robert J. Arceci, MD, PhD¹¹, Soheil Meshinchi, MD, PhD² and Marco A. Marra, PhD^1,12

¹Canada's Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada
²Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
³Michael Smith Genome Sciences Centre, British Columbia Cancer Agency, Vancouver, BC, Canada
⁴Seattle Children's Hospital, Seattle
⁵Office of Cancer Genomics, National Cancer Institute, Bethesda, MD
⁶Fred Hutchinson Cancer Research Ctr., Seattle, WA
⁷Nemours Center for Cancer and Blood Disorders, Alfred I. duPont Hospital for Children, Wilmington, DE
⁸Division of Hematology/Oncology/Bone Marrow Transplantation, Children's Mercy Hospitals and Clinics, Kansas City, MO
⁹Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD
¹⁰Keck School of Medicine, University of Southern California, Los Angeles, CA
¹¹Ronald A. Matricaria Institute of Molecular Medicine, Phoenix Children's Hospital, Phoenix, AZ
¹²Department of Medical Genetics, University of British Columbia, Vancouver, BC, Canada

Xiaoyu Qu, PhD^1,2*, Megan Othus, PhD^1,3*, Jerry Davison, PhD^1*, Liying Yan^4*, Elihu H. Estey, MD^2,5,6*, Jerry Radich, MD^1,2,3,7, Harry P. Erba, MD, PhD^3,8, Frederick R. Appelbaum, MD^1,2,3,7 and Min Fang, MD, PhD^1,2,3,7*

¹Fred Hutchinson Cancer Research Center, Seattle, WA
²Seattle Cancer Care Alliance, Seattle, WA
³SWOG Leukemia Committee, Portland, OR
⁴EpigenDx, Inc., Boston, MA
⁵Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA
⁶Division of Hematology, University of Washington, Seattle, WA
⁷University of Washington, Seattle, WA
⁸Internal Medicine, Hematology/Oncology, University of Alabama at Birmingham, Birmingham, AL

John S. Welch, MD, PhD¹, Allegra Petti, PhD^2*, Christopher A. Miller, PhD^3*, Daniel C. Link, MD⁴, Matthew J. Walter, MD⁵, Catrina C. Fronick^6*, Robert S. Fulton, PhD^7*, Lukas D. Wartman, MD⁸, Geoffrey L. Uy, MD⁴, Armin Ghobadi, MD⁹, Michael Tomasson⁹, Iskra Pusic, MD¹⁰, Rizwan Romee, MD¹⁰, Todd A Fehniger, MD, PhD¹⁰, Keith Stockerl-Goldstein¹¹, Ravi Vij, MBBS⁹, Stephen Oh, MD PhD¹², Camille N. Abboud, MD, FACP¹⁰, Amanda F. Cashen, MD⁸, Mark A. Schroeder, MD¹⁰, Meagan A. Jacoby, MD, PhD⁵, Peter Westervelt, MD, PhD¹³, John F Dipersio, MD, PhD⁸, Richard K Wilson, PhD^14* and Timothy J. Ley, MD¹⁵

¹Division of Oncology, Washington University School of Medicine, St. Louis, MO
²Washington University, The Genome Institute, St Louis, MO
³McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO
⁴Division of Oncology, Washington University School of Medicine, Saint Louis, MO
⁵Department of Medicine, Division of Oncology, Washington University in St. Louis, Saint Louis, MO
⁶McDonnell Genome Institute, Washington University in St. Louis, Saint Louis, MO
⁷McDonnell Genome Institute, Washington University, St Louis, MO
⁸Division of Oncology, Department of Medicine, Washington University School of Medicine, Saint Louis, MO
⁹Siteman Cancer Center, Washington University, St Louis, MO
¹⁰BMT and Leukemia Program, Washington University School of Medicine, Saint Louis, MO
¹¹Washington University School of Medicine, Siteman Cancer Center, Saint Louis, MO
¹²Division of Hematology, Washington University School of Medicine, St. Louis, MO
¹³Department of Medicine, Division of Oncology, Washington University School of Medicine, St. Louis, MO
¹⁴Washington University School of Medicine, Saint Louis, MO
¹⁵Washington University School of Medicine, St. Louis, MO

Luise Hartmann, MSc^1,2,3*, Sebastian Vosberg, MSc^1,2,3*, Klaus H. Metzeler, MD^1,2,3, Daniela Schumacher^2*, Friederike Pastore, MD^1,2,3, Kathrin Bräundl^1,2,3*, Evelyn Zellmeier^2*, Bianka Ksienzyk^2*, Nikola P Konstandin, PhD^2*, Stephanie Schneider, PhD^4*, Stefan Krebs, PhD^5*, Alexander Graf, PhD^5*, Helmut Blum, PhD^5*, Martin Neumann, MD^6,7*, Claudia D Baldus, MD^6,7, Stefan K. Bohlander, MD^8*, Wolfgang Hiddemann, MD^2,3,9, Karsten Spiekermann, MD^1,2,3 and Philipp A. Greif, MD^1,2,3

¹German Cancer Consortium (DKTK), Munich, Germany
²Department of Internal Medicine III, University Hospital Grosshadern, Ludwig-Maximilians-Universität, Munich, Germany
³German Cancer Research Center (DKFZ), Heidelberg, Germany
⁴Laboratory for Leukemia Diagnostics, Dept. of Internal Medicine III, University Hospital Großhadern, Ludwig-Maximilians-Universität, Munich, Germany
⁵Laboratory for Functional Genome Analysis, Gene-Center, Ludwig-Maximilians-University, Munich, Germany
⁶Department of Hematology and Oncology, Charité University Hospital, Berlin, Germany
⁷German Cancer Consortium (DKTK), Berlin, Germany
⁸Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand
⁹German Cancer Consortium (DKTK), Heidelberg, Germany