-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

614.O1.6 614. Acute Lymphoblastic Leukemia: Therapy, excluding Transplantation: Advances in Immunotherapy

Acute Lymphoblastic Leukemia: Therapy, excluding Transplantation Program: Oral and Poster Abstracts
Type: Oral
Monday, December 7, 2015: 2:45 PM-4:15 PM
W224CDGH, Level 2 (Orange County Convention Center)
Moderators:
Renato Bassan, MD, Ospedale dell'Angelo & Ospedale SS. Giovanni e Paolo and Alan S. Wayne, MD, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California

Disclosures:
Wayne: NIH: Patents & Royalties ; Medimmune: Honoraria , Other: travel support , Research Funding ; Kite Pharma: Honoraria , Other: travel support ; Pfizer: Honoraria ; Spectrum Pharmaceuticals: Honoraria , Other: travel support , Research Funding .
2:45 PM

Giovanni Martinelli, MD1*, Hervé Dombret2, Patrice Chevallier, MD, PhD3*, Oliver G. Ottmann, MD4*, Nicola Goekbuget, MD5, Max S. Topp, MD6, Adele K. Fielding, MB BS, PhD7, Lulu Ren Sterling, PhD8*, Jonathan Benjamin, MD9 and Anthony Selwyn Stein, MD10

1Institute of Hematology, S.Orsola-Malpighi University Hospital, Bologna, Italy
2Hematology, Hôpital Saint-Louis, Paris, France
3Department of Hematology, Nantes University Hospital, Nantes, France
4Department of Haematology, Cardiff University, Cardiff, United Kingdom
5Department of Medicine II, Goethe University, Frankfurt, Germany
6Department of Internal Medicine II, Division of Hematology and Medical Oncology, Wuerzburg University Medical Center, Wuerzburg, Germany
7Department of Hematology, UCL Cancer Institute, London, United Kingdom
8Amgen Inc., San Francisco, CA
9Amgen Inc., Thousand Oaks, CA
10Gehr Leukemia Center, City of Hope Medical Center, Duarte, CA

3:00 PM

Nicola Gökbuget, MD1, Hervé Dombret, MD, PhD2, Massimiliano Bonifacio, MD3*, Albrecht Reichle, MD4*, Carlos Graux, MD PhD5*, Christoph Faul, MD6, Helmut Diedrich, MD7*, Max S. Topp, MD8, Monika Brüggemann, MD9*, Heinz A. Horst, MD, PhD10, Julia Stieglmaier, PhD11*, Hendrik Wessels, MD11*, Vincent Haddad, MSc12*, Gerhard Zugmaier, MD11, Dirk Nagorsen, MD13 and Ralf C Bargou, MD14

1Department of Medicine II, Goethe University, Frankfurt, Germany
2Hôpital Saint-Louis, AP-HP, Paris, France
3Department of Medicine, Section of Hematology, University of Verona, Verona, Italy
4University Hospital, Regensburg, Germany
5Department of Hematology, CHU UcL Namur, Mont-Godinne, Belgium
6Department of Hematology and Oncology, University of Tuebingen, Tuebingen, Germany
7Medizinische Hochschule, Hannover, Germany
8Department of Internal Medicine II, Division of Hematology and Medical Oncology, Wuerzburg University Medical Center, Wuerzburg, Germany
9Department of Hematology, University Hospital Schleswig-Holstein, Kiel, Germany
10Department of Internal Medicine II, University Hospital Schleswig Holstein, Campus Kiel, Kiel, Germany
11Amgen Research (Munich) GmbH, Munich, Germany
12Amgen Ltd., Cambridge, England
13Global Clinical Development, Amgen, Thousand Oaks, CA
14Department of Hematology and Oncology, University Hospital Wurzburg, Wurzburg, Germany

3:15 PM

Stephan A. Grupp, MD, PhD1,2, Shannon L Maude, MD, PhD1,2, Pamela A Shaw, PhD3*, Richard Aplenc, MD, PhD1,2, David M. Barrett, MD, PhD2,4*, Colleen Callahan, MSN2*, Simon F. Lacey, PhD, BS5*, Bruce L. Levine, PhD6, J Joseph Melenhorst, PhD5*, Laura Motley, RN2*, Susan R. Rheingold, MD1,2, David T Teachey, MD1,2, Patricia A. Wood, MD, PhD7, David Porter, MD8 and Carl H. June, MD5,9

1Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
2Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA
3Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA
4Department of Pediatrics, University of Pennsylvania, Philadelphia, PA
5Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA
6Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
7Cell & Gene Therapies Unit, Novartis Pharmaceuticals Corporation, East Hanover, NJ
8Bone Marrow and Stem Cell Transplant Program, Abramson Cancer Center of the University of Pennsylvania, Philadelphia, PA
9Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA

3:30 PM

Jae H Park, MD1, Isabelle Riviere, PhD2, Xiuyan Wang, PhD2*, Yvette Bernal, MS3*, Terence Purdon4*, Elizabeth Halton, RN, MS, ANP5*, Yongzeng Wang, PhD2*, Kevin J. Curran, MD6, Craig S. Sauter, MD7, Michel Sadelain, MD, PhD2 and Renier J. Brentjens, MD, PhD2

1Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
2Center for Cell Engineering, Memorial Sloan Kettering Cancer Center, New York, NY
3Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
4Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY
5Memorial Sloan Kettering Cancer Center, New York, NY
6Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY
7Department of Medicine, Adult Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY

3:45 PM

Shannon L Maude, MD, PhD1,2, David M. Barrett, MD, PhD1,3*, David E Ambrose4*, Susan R. Rheingold, MD1,2, Richard Aplenc, MD, PhD1,2, David T Teachey, MD1,2, Colleen Callahan, MSN1*, Christine S Barker5*, Maya Mudambi5*, Pamela A Shaw, PhD6*, Jennifer Brogdon, PhD7*, Regina M Young, PhD4*, John Scholler4*, Andreas Loew, PhD7*, Katherine T. Marcucci, PhD8*, Jeffrey Finklestein4*, Irina Kulikovskaya, PhD4*, Farzana Nazimuddin4*, Zhaohui Zheng, MS9,10*, Bruce L. Levine, PhD8,9, David L Porter, MD11, Simon F. Lacey, PhD, BS10*, Jan J. Melenhorst, PhD8*, Carl H. June, MD10,11,12 and Stephan A. Grupp, MD, PhD1,2

1Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA
2Department of Pediatrics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
3Department of Pediatrics, University of Pennsylvania, Philadelphia, PA
4Center for Cellular Immunotherapies, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA
5Center for Childhood Cancer Research, Children’s Hospital of Philadelphia, Philadelphia, PA
6Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA
7Novartis Institute for Biomedical Research, Cambridge, MA
8Center for Cellular Immunotherapies, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
9Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
10Center for Cellular Immunotherapies, University of Pennsylvania, Philadelphia, PA
11Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
12Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA

4:00 PM

Daniel W. Lee III, MD1, Maryalice Stetler-Stevenson, MD, PhD2, Constance M. Yuan, MD, PhD2*, Terry J. Fry, M.D.1, Nirali N Shah, MD1, Cindy Delbrook, RN3*, Bonnie Yates, RN, PNP3*, Hua Zhang, Ph.D.3*, Ling Zhang, Ph.D.3*, James N. Kochenderfer, MD4, Steven A. Rosenberg, MD, PhD5*, David Stroncek, MD6 and Crystal L. Mackall, MD3

1Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD
2Laboratory of Pathology, National Cancer Institute, Bethesda, MD
3Pediatric Oncology Branch, National Cancer Institute/National Institutes of Health, Bethesda, MD
4Experimental Transplantation and Immunology Branch, National Cancer Institute/National Institutes of Health, Bethesda, MD
5Surgery Branch, NCI, NIH, Bethesda, MD
6Department of Transfusion Medicine, Clinical Center, National Institutes of Health, Bethesda, MD

*signifies non-member of ASH