-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

322.O2.6 322. Disorders of Coagulation or Fibrinolysis: Novel Treatment Strategies in Hemophilia

Disorders of Coagulation or Fibrinolysis Program: Oral and Poster Abstracts
Type: Oral
Monday, December 7, 2015: 10:30 AM-12:00 PM
W311ABCD, Level 3 (Orange County Convention Center)
Moderators:
Rodney M. Camire, PhD, Children's Hospital of Philadelphia and Yesim G. Dargaud, MD, PhD, Hopital Edouard Herriot Pav. E

Disclosures:
Camire: Pfizer: Consultancy , Patents & Royalties , Research Funding ; Novo Nordisk: Research Funding ; Spark Therapeutics: Membership on an entity’s Board of Directors or advisory committees .
10:30 AM

Robert Klamroth1*, Toshko Lissitchkov, MD2*, Luminita Rusen3*, Olaf Walter, MD, MBA4*, Johann Bichler, PhD4*, K John Pasi5, Andreas Tiede, MD, PhD6 and Sigurd Knaub, PhD4

1Vivantes Clinic Friedrichshain, Berlin, Germany
2Department of Coagulation Disorders and Anemia, SHAT Joan Pavel, Sofia, Bulgaria
3Sanador SR, Bucharest, Romania
4Octapharma AG, Lachen SZ, Switzerland
5Royal London Haemophilia Centre, Barts and the London School of Medicine and Dentistry, London, United Kingdom
6Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

10:45 AM

Elena Santagostino, MD, PhD1, Christine Voigt, PhD2*, Denise Wolko2*, Grace Cole2*, Yanyan Li, PhD2* and Iris C. Jacobs, MD2

1Centro Emofilia e Trombosi, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy
2CRD, CSL Behring, King of Prussia, PA

11:00 AM

Junjiang Sun, MD1*, Eric Livingston2*, Tom Knudsen, DVM, PhD3*, Dougald M. Monroe III, PhD4, Mirella Ezban, Ph.D.5*, Ted Bateman, PhD6* and Paul E. Monahan, MD7

1Gene Therapy Center, University of North Carolina, Chapel Hill, NC
2Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC, NC
3Novo Nordisk A/S, Maaloev, Denmark
4Division of Hematology/Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC
5Novo Nordisk, Maaloev, Denmark
6Department of Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC
7Department of Pediatrics and Gene Therapy Center, University of North Carolina at Chapel Hill, Chapel Hill, NC

11:15 AM

Peter Boross, PhD1*, Cafer Yildiz2*, Kamran Bakhtiari, PhD3*, Joost C.M. Meijers, Prof, PhD3 and C. Erik Hack, MD, PhD1,2*

1Prothix B.V., Leiden, Netherlands
2Laboratorium for Translational Immunology, UMC Utrecht, Utrecht, Netherlands
3Department of Plasma Proteins, Sanquin Research, Amsterdam, Netherlands

11:30 AM

K John Pasi1, Pencho Georgiev2*, Tim Mant3*, Michael Desmond Creagh4*, Toshko Lissitchkov, MD5*, David Bevan6*, Steve Austin7*, Charles R Hay8*, Brigit Brand9, Rashid Kazmi10*, Pratima Chowdary11*, Margaret V Ragni12, Jihong Chen13*, Akin Akinc13*, Benny Sorensen13 and Savita Rangarajan14

1Royal London Haemophilia Centre, Barts and the London School of Medicine and Dentistry, London, United Kingdom
2University Multiprofile Hospital for Active Treatment “Sveti Georgi’, Plovdiv, Bulgaria
3Quintiles Drug Research Unit, London, United Kingdom
4Royal Cornwall Hospitals NHS Trust, Truro, United Kingdom
5Department of Coagulation Disorders and Anemia, SHAT Joan Pavel, Sofia, Bulgaria
6Guy's and St Thomas' Hospital NHS Trust, London, United Kingdom
7St. George’s Healthcare NHS Trust Haemophilia Centre, London, United Kingdom
8Manchester Royal Infirmary, Manchester, United Kingdom
9Universitaetsspital Zuerich, Zeurich, Switzerland
10University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom
11Royal Free Hospital, London, United Kingdom
12University of Pittsburgh and Hemophilia Center of Western Pennsylvania, Pittsburgh, PA
13Alnylam Pharmaceuticals, Cambridge, MA
14Southern Haemophilia Network, Hampshire Hospitals NHF Foundation Trust, London, United Kingdom

11:45 AM

Gili Kenet1,2, Tami Livnat3*, Emma Fosbury4*, Pratima Chowdary4*, Alfica Sehgal5*, Akin Akinc5* and Benny Sorensen5

1Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel
2National hemophilia center and the Institue of Thrombosis and Hemostasis, The Chaim Sheba Medical Centre, Ramat Gan, Israel
3Tel Hashomer Hospital, Tel Aviv, Israel
4Royal Free London NHS Foundation Trust, London, United Kingdom
5Alnylam Pharmaceuticals, Cambridge, MA

*signifies non-member of ASH