-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

114.O1.6 114. Hemoglobinopathies, Excluding Thalassemia – Clinical: Promising Therapies in Sickle Cell Disease

Hemoglobinopathies, Excluding Thalassemia – Clinical Program: Oral and Poster Abstracts
Type: Oral
Monday, December 7, 2015: 10:30 AM-12:00 PM
W340, Level 3 (Orange County Convention Center)
Moderators:
Jane A Little, MD, Case Western Reserve University and Maureen Okam, MD, MPH, Brigham and Women's Hosp.

Disclosures:
No relevant conflicts of interest to declare.
10:30 AM

Barbara Cappelli, MD1,2*, Francoise Bernaudin, MD3, Annalisa Ruggeri, MD, PhD4,5*, Myriam Labopin, MD6*, Fernanda Volt, MT1*, Belinda Pinto Simoes, M.D., Ph.D.7,8, Alina Ferster, MD, PhD9, Sophie Dupont, MD10*, Josu de la Fuente, PhD, FRCP, FRCPI, FRCPCH, FRCPath11, Jean-Hugues Dalle, MD, PhD12, Marco Zecca, MD13*, Marie Robin, MD, PhD14, Mark C. Walters, MD15, Nathalie Dhedin, MD16*, Gerard Michel, MD17*, Patrick Lutz18*, Benedicte Neven, MD, PhD19*, Yves Bertrand, MD, PhD20*, Jean Pierre Vannier, MD, PhD21*, Mouhab Ayas, MD22, Susanne Matthes, MD23*, Hanadi Elayoubi, MD1*, Agnes Devergie, MD1*, Chantal Kenzey, CRA1*, Franco Locatelli, MD24, Christina Peters, MD, PhD25*, Vanderson Rocha, MD, PhD26,27, Mary Eapen, MBBS28 and Eliane Gluckman, MD1

1Eurocord International Registry, Paris, France
2Monacord, Centre Scientifique de Monaco, Monaco, Monaco
3Dept. Pediatrie, Hopital Intercommunal de Creteil, Creteil, France
4Eurocord, Hôpital Saint Louis APHP, University Paris-Diderot, Paris, France
5Service d’Hématologie et Thérapie Cellulaire, Hôpital Saint-Antoine, Paris, France
6Department of Hematology and Cell Therapy, Saint Antoine Hospital, Paris, France
7University of São Paulo,, São Paulo, Brazil
8Ribeirão Preto Medical School, Ribeirao Preto, Brazil
9Dept. of Hémato-oncologie pédiatrique, Children's University Hospital Reine Fabiola, Brussels, Belgium
10Cliniques Universitaires Saint Luc, Hemato-Oncology Unit, Brussels, Belgium
11Centre for Haematology, Imperial College London, London, United Kingdom
12Hematology, Hopital Robert Debre, Paris, France
13Pediatric Hematology/Oncology, IRCCS Policlinico San Matteo, Pavia, Italy
14Hematology - Bone Marrow Transplantation, Saint-Louis Hospital, Paris, France
15UCSF Benioff Children's Hospital, Oakland, CA
16Department of Hematology, Adolescents and young adults unit, Saint-Louis Hospital, Paris, France
17Timone Enfants Hospital and Aix-Marseille University, Department of Pediatric Hematology and Oncology, Marseille, France
18CHRU Strasbourg, Strasbourg, France
19Pediatric Hematology-Immunology and Rheumatology Unit, Assistance Publique-Hôpitaux de Paris, Necker-Enfants Malades University Hospital, Paris, France
20Pediatric Hematology and Oncology Unit, IHOP, Lyon, France
21Paediatric Oncology and Haematology Unit, Charles Nicolle Rouen University Hospital, Rouen, France
22Department of Pediatric Hematology/Oncology, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia
23St Anna Children's Hospital, Vienna, Austria
24Department of Pediatric Hematology and Oncology, IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy
25Stem Cell Transplantation Unit, St. Anna Children's Hospital, Vienna, Austria
26Churchill Hospital, Oxford University, Oxford, United Kingdom
27Eurocord - Monacord, Hôpital Saint Louis, Paris, France
28Medical College of Wisconsin, Milwaukee, WI

10:45 AM

Josh Lehrer-Graiwer, MD, MPhil, FACC1*, Jo Howard, MD2, Claire Jane Hemmaway, MD3*, Moji Awogbade4, Paul Telfer, FRCPath, MD5*, Mark Layton, MB, FRCP6*, Timothy Mant, MB, FFPM, FRCP7*, Kobina Dufu, PhD1*, Athiwat Hutchaleelaha, Ph.D.1*, Teri Koller, MBA1*, Donna Oksenberg, PhD1*, Mira Patel, PhD1* and Eleanor Ramos, MD1*

1Global Blood Therapeutics, South San Francisco, CA
2Department of Haematology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom
3ba, Romford, United Kingdom
4Department of Haematology, King's College Hospital, London, United Kingdom
5The Royal London Hospital, London, United Kingdom
6Imperial College NHS Foundation Trust, London, United Kingdom
7Quintiles Drug Research Unit at Guy’s Hospital, London, United Kingdom

11:00 AM

Lakshmanan Krishnamurti, MD1, Keith M. Sullivan, MD2, Naynesh R. Kamani, MD3, Edmund K Waller, MD, PhD4, Allistair Abraham, MD5, Federico Campigotto, MS6*, Wandi Zhang, M.D7*, Shannon Smith, MSN1*, Kathryn L. Hassell, MD8, Laura Decastro, MD9*, Catherine J Wu, MD10,11, Donna S. Neuberg, Sc.D.12 and Mark C. Walters, MD13

1Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Emory University, Atlanta, GA
2Division of Hematology/Oncology/ Blood and Marrow Transplantation, Duke University, Durham, NC
3AABB Center for Cellular Therapies, Washington, DC
4Winship Cancer Institute, Department of Hematology and Medical Oncology, Emory University, Atlanta, GA
5Childrens National Medical Center, Washington, DC
6Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA
7Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA
8University of Colorado Denver Health Sciences Center, Aurora, CO
9Division of Hematology/Oncology/BMT, University of Pittsburgh Medical Center, Pittsburgh, PA
10Department of Medical Oncology, Dana-Farber Cancer Inst., Boston, MA
11Dana-Farber Cancer Institute, Harvard Medical School, Boston
12Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA
13UCSF Benioff Children's Hospital Oakland, Oakland, CA

11:15 AM

Francoise Bernaudin1, Suzanne Verlhac2*, Elisabeth Ducros-Miralles1*, Regis Peffault Delatour3*, Jean-Hugues Dalle4, Eleonore Petras5*, Valentine Brousse6*, Isabelle Thuret7*, Catherine Paillard8*, Benedicte Neven9*, Claire Galambrun7*, Maryse Etienne-Julian10*, Corinne Pondarre11*, Laurence Lutz12*, Corinne Guitton13*, Florence Missud14*, Camille Runel15*, Charlotte Jubert16*, Gisele Elana17*, Manuela Vasile18*, Cecile Arnaud1*, Annie Kamdem1*, Florence Kasbi18*, Francois Gouraud19*, Francoise Freard1*, Fabienne Toutain20*, Gerard Socie21 and Sylvie Chevret22*

1Pediatrics, SCD Referral CHIC Center, Creteil, France
2Pediatric Radiology, SCD Referral CHIC Center, Creteil, France
3St-Louis Hospital, Hematology, Paris 7, Paris, France
4Debre Hospital, Pediatric Hematology, Paris, France
5CHU Guadeloupe, SCD Referral Center, Pointe à Pitre, France
6Pediatrics, SCD Referral Necker Center, Paris, France
7Pediatric Hematology, La Timone Hospital, Marseille, France
8Pediatric Hematology, CHU Strasbourg, Strasbourg, France
9Hôpital Universitaire Necker -Enfants Malades, Paris, France
10SCD Referral Guadeloupe Center, Pointe à Pitre, France
11SCD Referral Centre Hospitalier lntercommunal de Creteil, Creteil, France
12Pediatrics, CHRU Strasbourg Hospital, Strasbourg, France
13Pediatrics, SCD Referral Bicetre Center, Kremlin-Bicetre, France
14Pediatric Hematology Immunology, SCD Referral Debre Center, Paris, France
15Pediatric Oncology Hematology, Bordeaux Hospital, Bordeaux, France
16Pediatric Onco-hematology, Hôpital des Enfants, Bordeaux, France
17Pediatrics, SCD Referral Martinique Center, Fort de France, France
18Radiology, CHIC Hospital, Creteil, France
19Pediatrics, Meaux Hospital, Meaux, France
20Hemato-Pediatrics, CHU-Rennes, Rennes, France
21St-Louis Hospital, Paris, France
22Statistics St-Louis Hospital, Paris 7, Paris, France

11:30 AM

Carolyn C Hoppe, MD1, Eufemia Jacob, PhD, RN2*, Frans A. Kuypers, Ph.D.3 and Lori Styles, MD4*

1Hematology-Oncology, UCSF Benioff Children's Hospital Oakland, Oakland, CA
2School of Nursing, UCLA, Los Angeles, CA
3Children's Hospital Oakland Research Institute, Oakland, CA
4Pharmacyclics LLC, an AbbVie Company, Sunnyvale, CA

11:45 AM

Odianosen Eigbire-Molen1*, Deepika S. Darbari, MD2, Maria R. Ponisio, MD3*, Mikhail V. Milchenko, PhD3*, Mark J. Rodeghier, PhD4*, James F. Casella, MD5, Robert McKinstry, MD, PhD6* and Michael R. DeBaun, MD, MPH7

1Georgetown University School of Medicine, Washington, DC
2Division of Hematology and Oncology, Children's National Medical Center, Washington, DC
3Mallinckrodt Institute of Radiology, Washington University in St. Louis, School of Medicine, St Louis, MO
4Rodeghier Consultants, Chicago, IL
5Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD
6Mallinckrodt Institute of Radiology, Washington University in St. Louis, School of Medicine, St. Louis, MO
7Vanderbilt-Meharry-Matthew Walker Center of Excellence in Sickle Cell Disease, Vanderbilt University School of Medicine, Nashville, TN

*signifies non-member of ASH