Josephine Tabea Tauer, PhD^1*, Ingmar Glauche, PhD^2*, Meinolf Suttorp, MD, PhD¹ and all Participants of trial CML-PAED II^1*

¹Dpt of Pediatrics, Hematology/Oncology, University Hospital Carl Gustav Carus, Dresden, Germany
²Institute for Medical Informatics and Biometry, Faculty of Medicine Carl Gustav Carus, Technische Universität Dresden, Germany, Dresden, Germany

Dong-Wook Kim¹, Charles S. Cleeland, PhD^2*, Susanne Saussele³, Loretta A. Williams, PhD, APRN², Hesham Mohamed^4*, Javier Pinilla-Ibarz^5* and Elisabetta Abruzzese, MD⁶

¹Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, South Korea
²Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, TX
³III. Medizinische Klinik, Universitätsmedizin Mannheim, Universität Heidelberg, Mannheim, Germany
⁴Bristol-Myers Squibb, Plainsboro, NJ
⁵Department of Malignant Hematology, H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL
⁶Hematology, S. Eugenio Hospital, Roma, Italy

Frédéric Millot^1*, Joelle Guilhot, PhD¹, Meinolf Suttorp, Prof. Dr.², Anne Sophie Meunier, MD^3*, Gunes Adalet Meral, MD^4*, Petr Sedlacek, MD, PhD^5*, Eveline de Bont, MD, PhD⁶, Chi Kong Li, MD⁷, Krzysztof Kalwak^8*, Birgitte Lausen⁹, Srdjana Culic^10*, Barbara De Moerloose, MD, PhD^11*, Andrea Biondi, Prof, MD¹² and Andre Baruchel, MD¹³

¹Inserm CIC 1402, University Hospital, Poitiers, France
²Pediatric Hematology/Oncology, University Hospital Gustav Carus, Dresden, Germany
³Pediatric Hematology Oncology, University Hospital, Poitiers, France
⁴Department of Pediatric Hematology, Uludağ University Hospital, , Görükle Bursa, Turkey
⁵University Hospital Motol, Prague, Czech Republic
⁶University Medical Center Groningen, Groningen, Netherlands
⁷Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong, Hong Kong
⁸Department of Pediatric Hematology Oncology and Transplantation, Wroclaw Medical University, Wroclaw, Poland
⁹Department of Pediatrics, Rigshospitalet, Copenhagen, Denmark
¹⁰Department of Pediatric Hematology Oncology Immunology and Medical Genetic, University Hospital, Split, Croatia
¹¹Department of Pediatrics, Ghent University, Ghent, Belgium
¹²Centro Ricerca Tettamanti, Clinica Pediatrica, Università Milano Bicocca, Osp. San Gerardo/Fondazione MBBM, Monza (MB), Italy
¹³Pediatric Hematology and Immunology Department, Robert Debré Hospital - APHP and University Paris Diderot, Paris, France

Ghayas C. Issa, MD^1*, Hagop M. Kantarjian, MD², Elias Jabbour², Gautam Borthakur, MD², Srdan Verstovsek, MD², Sherry Pierce, BSN, BA^2*, William Wierda, MD, PhD², Alessandra Ferrajoli, MD², Guillermo Garcia-Manero, MD², Tapan Kadia, MD², Naval Daver, MD², Naveen Pemmaraju, MD², Farhad Ravandi, MD², Sara Emogene DellaSala, BS^2* and Jorge E. Cortes, MD²

¹Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Franck E. Nicolini, MD, PhD^1,2, Gabriel Etienne, MD, PhD^2,3*, Viviane Dubruille, MD^2,4*, Lydia Roy, MD^2,5*, Françoise Huguet, MD^2,6*, Laurence Legros, MD^2,7*, Stéphane Giraudier, MD, PhD^2,8*, Valérie Coiteux, MD^2,9*, Agnes Guerci-Bresler, MD^2,10*, Pascal Lenain, MD^2,11*, Delphine Rea^2,12*, Shanti Amé, MD^2,13*, Pascale Cony-Makhoul, M.D.^2,14*, Martine Gardembas, MD^2,15*, Eric Hermet, MD^2,16*, Philippe Rousselot, MD, PhD^2,17*, Marie-Claude Gagnieu, PharmD, PhD^18*, Stéphane Morisset, Stat^1*, Christine Pivot, PharmD^19*, Madeleine Etienne, CRA^1,2*, Francois Guilhot, MD^2,20, Stéphanie Dulucq, PharmD, PhD^21* and Francois-Xavier Mahon, MD, PhD, Professor^2,3*

¹Hematology department 1G, Centre Hospitalier Lyon Sud, Pierre Bénite, France
²Fi-LMC group, Pessac, France
³Hematology department, Institut Bergonié, Bordeaux, France
⁴Department of Hematology, Nantes University Hospital, Nantes, France
⁵Hematology department, CHU de Poitiers, Poitiers, France
⁶Hematology department, Institut universitaire du cancer de Toulouse, Toulouse, France
⁷Hematology department, Hopital Archet 1, CHU Nice, Nice, France
⁸Hematology department, Hôpital Henri Mondor, Créteil, France
⁹Hematology department, Hôpital Claude Huriez, Lille, France
¹⁰Hematology department, Hôpital d'Adultes du Brabois, CHU Nancy, Nancy, France
¹¹Hematology department, Centre Henri Becquerel, Rouen, France
¹²Hematology department, Hôpital Saint-Louis, Paris, France
¹³Hematology department, Hôpital Civil , CHU Strasbourg, Strasbourg, France
¹⁴Hematology department, Centre Hospitalier Annecy-Genevois, Site Annecy, Metz-Tessy, France
¹⁵Hematology Department, University Hospital, Angers, France
¹⁶Hematology department, CHU d’Estaing, Clermont-Ferrand, France
¹⁷Hematology Department, Hôpital André Mignot, Versailles, France
¹⁸Pharmacology laboratory, Hôpital Edouard Herriot, Lyon, France
¹⁹Central Pharmacy, Hôpital Edouard Herriot, Lyon, France
²⁰Hematology department, Inserm CIC 1402, CHU de Poitiers, Poitiers, France
²¹Laboratory of Hematology, Hôpital Haut Lévêque, Pessac, France

Giuseppe Saglio¹, Sonya J. Snedecor, PhD^2*, Xiang Ji^2*, Ming-Hui Tai, BPharm, MHPA, PhD^2*, David Ray, PharmD, MBA^3,4*, Estella Mendelson, BSRN, MBA^3*, Aby Buchbinder^3*, Pascal Edrich^5* and Francois-Xavier Mahon, MD, PhD, Professor^6*

¹University of Turin, Orbassano, Italy
²Pharmerit International, Bethesda, MD
³Novartis Pharmaceuticals Corporation, East Hanover, NJ
⁴Rutgers Ernest Mario School of Pharmacy, New Brunswick, NJ
⁵Novartis Pharma AG, Basel, Switzerland
⁶Laboratoire Hématopoïèse Leucémique et Cible Thérapeutique, Inserm U1035, Université Victor Ségalen, Bordeaux, France

Preetesh Jain, MBBS, MD, DM, PhD^1*, Hagop M Kantarjian, MD², Elias Jabbour^3*, Zeev Estrov, MD², Gautam Borthakur, MD², Naveen Pemmaraju, MD², Tapan Kadia, MD², Naval Daver, MD², Farhad Ravandi, MD², Srdan Verstovsek, MD², Susan O'Brien, MD⁴ and Jorge E. Cortes, MD⁵

¹Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³University of Texas, The MD Anderson Cancer Center, Houston
⁴University of California - Irvine, Orange, CA
⁵Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX

Christian T. Dietz, PhD^1*, Alice Charlotte Fabarius, PhD^1*, Michael Lauseker, PhD^2*, Susanne Saussele¹, Lida Kalmanti^1*, Sébastien Rinaldetti^1*, Claudia Haferlach, MD³, Brigitte Schlegelberger, MD, PhD⁴, Martine Jotterand^5*, Alois Gratwohl⁶, Axel R. Zander, Professor⁷, Nicolaus Kröger^7*, Dietrich W. Beelen, MD⁸, Jürgen Novotny^9*, Christoph Nerl^10*, Christof Scheid¹¹, Karsten Spiekermann¹², Jiri Mayer, MD¹³, Herbert G. Sayer¹⁴, Christiane Falge^15*, Donald Bunjes, MD^16*, Hartmut Döhner, Prof. Dr.¹⁷, Arnold Ganser¹⁸, Peter Brossart, MD¹⁹, Rainer Schwerdtfeger²⁰, Herrad Baumann^20*, Rolf Kuse^21*, Hans Walter Lindemann, MD^22*, Matthias Bormann^23*, Bernd Hertenstein, MD^23*, Gabriela M. Baerlocher²⁴, Carlo Aul, MD^25*, Peter Staib^26*, Matthias Edinger, MD²⁷, Michael Schatz^28*, Axel A Fauser²⁹, Renate Arnold, MD³⁰, Dieter K. Hossfeld, MD^31*, Hans-Jochem Kolb¹², Susanne Schnittger, PhD³, Martin C. Müller, MD^1*, Andreas Reiter, MD^1*, Andreas Hochhaus, MD³², Markus Pfirrmann^2*, Joerg Hasford^2*, Michele Baccarani³³ and Ruediger Hehlmann, MD¹

¹III. Medizinische Klinik, Medizinische Fakultät Mannheim der Uni Heidelberg, Mannheim, Germany
²Institut für medizinische Informationsverarbeitung, Biometrie und Epidemiologie, Ludwig-Maximilians-Universität, München, Germany
³MLL Münchner Leukämielabor, München, Germany
⁴Institut für Humangenetik, Medizinische Hochschule, Hannover, Germany
⁵Service de génétique médicale, Centre Hospitalier Universitaire Vaudois (CHUV),, Lausanne, Switzerland
⁶Behandlungszentrum Stammzelltransplantation, Universitätsspital, Basel, Switzerland
⁷Interdisziplinäre Klinik und Poliklinik für Stammzelltransplantation, Universitätsklinikum Eppendorf, Hamburg, Germany
⁸Klinik für Knochenmarktransplantation, Universitästsklinikum, Essen, Germany
⁹Klinik für Hämatologie, Universitätsklinikum, Essen, Germany
¹⁰Klinik für Hämatologie, Onkologie, Immunologie, Palliativmedizin, Infektiologie und Tropenmedizin, Klinikum Schwabing, München, Germany
¹¹Klinik I für Innere Medizin, Universitätsklinikum, Köln, Germany
¹²Medizinische Klinik und Poliklinik III, Klinikum der Ludwig-Maximilians-Universität, München, Germany
¹³Interní hematologická a onkologická klinika, Masarykova univerzita, Brno, Czech Republic
¹⁴Klinik für Innere Medizin II, Universitätsklinikum, Jena, Germany
¹⁵Medizinische Klinik 5, Klinikum Nürnberg-Nord, Nürnberg, Germany
¹⁶Department of Internal Medicine III, University of Ulm, Ulm, Germany
¹⁷Klinik für Innere Medizin III, Universitätsklinikum, Ulm, Germany
¹⁸Klinik für Hämatologie, Hämostaseologie, Onkologie und Stammzelltransplantation, Medizinische Hochschule, Hannover, Germany
¹⁹Medizinische Klinik III für Hämatologie und Onkologie, Universitätsklinikum, Bonn, Germany
²⁰KMT-Zentrum, Deutsche Klinik für Diagnostik, Wiesbaden, Germany
²¹Abteilung für Hämatologie und Stammzelltransplantation, Asklepios Klinik St. Georg, Hamburg, Germany
²²Klinik für Hämatologie und Onkologie, St.-Marien-Hospital, Hagen, Germany
²³I. Medizinische Klinik, Klinikum Bremen-Mitte, Bremen, Germany
²⁴Universitätsklinik für Hämatologie und hämatologisches Zentrallabor, Inselspital, Bern, Switzerland
²⁵Klinik für Onkologie und Hämatologie, HELIOS St. Johannes Klinik, Duisburg, Germany
²⁶Klinik für Hämatologie und Onkologie, St. Antonius Hospital, Eschweiler, Germany
²⁷Abteilung Hämatologie und Internistische Onkologie, Universitätsklinikum, Regensburg, Germany
²⁸II. Medizinische Klinik, St. Vincentius Kliniken, Karlsruhe, Germany
²⁹Klinik für Knochenmarktransplantation und Hämatologie/Onkologie, Idar-Oberstein, Germany
³⁰Medizinische Klinik mit Schwerpunkt Hämatologie, Onkologie und Tumorimmunologie, Campus Virchow-Klinikum, Charité - Universitätsmedizin, Berlin, Germany
³¹II. Medizinische Klinik, Universitätsklinikum Eppendorf, Hamburg, Germany
³²Universitätsklinikum Jena, Jena, Germany
³³Istituto di Ematologia, Universita di, Bologna, Italy

Alessandra Iurlo, MD, PhD^1*, Roberto Latagliata, MD^2*, Cristina Bucelli, MD^3*, Dario Ferrero, MD^4*, Fausto Castagnetti, MD/PhD⁵, Massimo Breccia, MD^6*, Elisabetta Abruzzese, MD⁷, Daniele Cattaneo, MD^8*, Carmen Fava, MD^9*, Antonella Gozzini, MD^10*, Mario Annunziata, MD^11*, Mario Tiribelli, MD^12*, Patrizia Pregno, MD^13*, Fabio Stagno, MD/PhD¹⁴, Paolo Vigneri, MD/PhD^15*, Francesco Cavazzini, MD¹⁶, Gianni Binotto^17*, Giovanna Mansueto, MD^18*, Sabina Russo, MD^19*, Franca Falzetti, MD²⁰, Enrico Montefusco, MD^21*, Gabriele Gugliotta, PhD^22*, Cristiana Gasbarrino, MD^23*, Ada D'Addosio, MD^24*, Laura Cortesi^25*, Michele Cedrone, MD^26*, Antonella Russo Rossi, MD^27*, Paolo Avanzini, MD^28*, Mauro Endri, MD^29*, Antonio Spadea, MD³⁰, Francesca Celesti, MD^31*, Gianfranco Giglio, MD^32*, Alessandro Isidori, M.D. PhD³³, Monica Crugnola, MD^34*, Elisabetta Calistri^35*, Federica Sorà, MD, PhD^36*, Giovanna Rege-Cambrin, MD^37*, Simona Sica^38*, Luigia Luciano, MD³⁹, Ester Maria Orlandi, MD^40*, Monica Bocchia, MD^41*, Mauro Tettamanti^42*, Giuliana Alimena, MD⁴³, Giuseppe Saglio, MD PhD^44*, Gianantonio Rosti, MD^45*, Alessandro Nobili^42*, Pier Mannuccio Mannucci, MD⁴⁶ and Agostino Cortelezzi, MD⁴⁷

¹Division of Hematology, IRCCS Maggiore Policlinico Hospital Foundation, Milano, Italy
²Division of Hematology-Dept. of Cellular Biotechnologies and Hematology, University La Sapienza of Rome, Rome, Italy
³Oncohematology Division, IRCCS Ca' Granda - Maggiore Policlinico Hospital Foundation, University of Milan, Milano, Italy
⁴Chair of Hematology, Department of Medicine and Experimental Oncology, Torino, Italy
⁵Bologna University School of Medicine, Bologna, Italy
⁶Dipartimento di Ematologia e Biotecnologie, Università La Sapienza, Rome, Italy
⁷Hematology, S. Eugenio Hospital, Roma, Italy
⁸Department of Hematology, IRCCS Maggiore Policlinico Hospital Foundation, Milan, Italy
⁹Division of Internal Medicine - Hematology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Italy
¹⁰Hematology Unit, AOU Careggi, Firenze, Italy
¹¹Hematology, OSPEDALE CARDARELLI, NAPOLI, Italy
¹²Division of Hematology and BMT, Department of Experimental and Clinical Medical Sciences, Azienda Ospedaliero-Universitaria di Udine, Udine, Italy
¹³Hematology Unit, AZ OSP. CITTA' DELLA SALUTE E SCIENZA TORINO, TORINO, Italy
¹⁴Section of Hematology, A.O.U. Policlinico, Catania, Italy
¹⁵Dep. Clinical and Experimental Medicine, University of Catania Medical School, Catania, Italy
¹⁶Haematology Dept., University of Ferrara, Ferrara, Italy
¹⁷Department of Medicine, Hematology and Clinical Immunology Section, University of Padova, Padova, Italy
¹⁸Department of Onco-Hematology, IRCCS-CROB, Rionero in Vulture, Italy
¹⁹Hematology Unit, University of Messina, Messina, Italy
²⁰University of Perugia, Perugia, Italy
²¹Hematology Unity, Sant'Andrea Hospital, Rome, Italy
²²"Seràgnoli" Institute of Hematology, Bologna University School of Medicine, Bologna, Italy
²³Onco-Hematology Unit, Università Cattolica Giovanni Paolo II, Campobasso, Italy
²⁴Hematology, Villa San Pietro Hospital, Rome, Italy
²⁵Department of Neuroscience, IRCCS - Istituto di Ricerche Farmacologiche, Milano, Italy
²⁶UOC of Hematology, San Giovanni - Addolorata Hospital, Rome, Italy
²⁷Hematology, University of Bari, Bari, Italy
²⁸Hematology, S.Maria Nuova Hospital, Reggio Emilia, Italy
²⁹Hematology Unit, Pordenone Hospital, Pordenone, Italy
³⁰Clinical Oncology, Istituto Regina Elena, Rome, Italy
³¹Hematology, Belcolle Hospital, Viterbo, Italy
³²Hematology, Cardarelli Hospital, Campobasso, Italy
³³Hematology and Stem Cell Transplant Center, AORMN Hospital, Pesaro, Italy
³⁴Clinical and Experimental Medicine, University of Parma, Parma, Italy
³⁵Hematology Unit, Ospedale Ca' Foncello, Treviso, Treviso, Italy
³⁶Università Cattolica del Sacro Cuore, Rome, Italy
³⁷Division of Hematology and Internal Medicine, University of Turin, "San Luigi Gonzaga" University Hospital, Orbassano, Italy
³⁸Institute of Hematology, Catholic University, Rome, Italy
³⁹University of Naples Federico II, Napoli, Italy
⁴⁰Dept of Oncology-Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
⁴¹Department of Hematology and Transplants, University of Siena, Siena, Italy
⁴²Department of Neuroscience, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Milano, Italy
⁴³Department of Cellular Biotechnologies and Hematology, Sapienza University, Rome, Italy
⁴⁴Clinic of Internal Medicine and Hematology, Università di Torino - Ospedale San Luigi, 10043 Orbassano-Torino, Italy
⁴⁵Department of Hematology and Oncological Sciences, Bologna, Italy
⁴⁶Scientific Direction, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milano, Italy
⁴⁷Oncohematology Unit, University of Milan, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy

Mariko Minami, MD^1*, Toshihiro Miyamoto, MD, PhD¹, Takeshi Arita, MD, PhD^1*, Tomohiko Kamimura, MD, PhD^2*, Junichiro Yuda, MD^1*, Yoshikane Kikushige, MD, PhD^1*, Yasuo Mori, MD, PhD^1*, Goichi Yoshimoto, MD, PhD^1*, Kenjiro Kamezaki, MD, PhD¹, Koji Kato, MD, PhD¹, Motoaki Shiratsuchi, MD, PhD^3*, Katsuto Takenaka, MD, PhD¹, Hiromi Iwasaki, MD, PhD^1*, Satoshi Yamasaki, MD, PhD^4*, Tsuyoshi Muta, MD, PhD^5*, Kazuki Tanimoto, MD, PhD^6*, Ryosuke Ogawa, MD, PhD⁵, Tetsuya Eto, MD, Ph.D^7* and Koichi Akashi, MD, PhD^1*

¹Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
²Department of Hematology, Harasanshin Hospital, Fukuoka, Japan
³Department of Medicine and Bioregulatory Science, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan
⁴Kyushu Medical Center, Fukuoka, Japan
⁵Department of Hematology / Oncology, Japan Community Healthcare Organization Kyushu Hospital, Kita-Kyushu, Japan
⁶Japanese Red Cross Fukuoka Hospital, Fukuoka, Japan
⁷Department of Hematology, Hamanomachi Hospital, Fukuoka, Japan

Stuart Goldberg, MD¹ and Stephanie Hamarman, MD^2*

¹Division of Leukemia, John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ
²NYC Psychiatry, New York, NY

Qian Jiang^1*, Zheng-Chen Liu^2*, Song-Xin Zhang^2*, Jing Li^2* and Robert Peter Gale, MD, PhD, DSc^3,4

¹Peking University People's Hospital, Beijing, China
²New Sunshine Charity Foundation, Beijing, China
³Imperial College, London, United Kingdom
⁴Celgene Corp., Summit, NJ

Niklas Gunnarsson, MD^1*, Martin Hoglund, MD, PhD², Leif Stenke, MD, PhD³, Solveig Wallberg Jonsson, MD, PhD^4*, Fredrik Sandin, PhD^5*, Magnus Bjorkholm, MD, PhD⁶, Arta Dreimane, MD, PhD^7*, Mats Lambe, MD, PhD^8*, Berit Markevarn, MD^9*, Ulla Olsson-Stromberg, MD, PhD^10*, Hans Wadenvik, MD, PhD^11*, Johan Richter, MD, PhD^12* and Anders Sjalander, MD, PhD^13*

¹Department of Public Health and Clinical Medicine, UmeA University, Gavle, Sweden
²Uppsala University, Department of Medical Sciences, Section of Hematology, Uppsala, Sweden
³Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden
⁴Department of Public Health and Clinical Medicine, Umea University, Umea, Sweden
⁵Regional Cancer Centre, Uppsala-Orebro, Uppsala, Sweden
⁶Department of Medicine, Division of Hematology, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden
⁷Departement of Hematology, Linkoping University Hospital, Linkoping, Sweden
⁸Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
⁹Department of Hematology, Umea University Hospital, Umea, Sweden
¹⁰Department of Medical Science and Division of Hematology, Uppsala University Hospital, Uppsala, Sweden
¹¹Department of Hematology, Sahlgrenska University Hospital, Göteborg, Sweden
¹²Department of Hematology and Vascular Disorders, Skane University Hospital, Lund, Sweden
¹³Department of Public Health and Clinical Medicine, Umea University, Sundsvall, Sweden

Mary Akosile, BA^1*, Sherry Pierce, BSN, BA^2*, Mark Brandt, BS^3*, Srdan Verstovsek, MD², Gautam Borthakur, MD², Hagop Kantarjian, MD³, Farhad Ravandi, MD³, William Wierda, MD, PhD³, Guillermo Garcia-Manero, MD³, Naval Daver, MD³, Tapan Kadia, MD³, Jan A. Burger, MD, PhD³, Naveen Pemmaraju, MD², Elias Jabbour² and Jorge E. Cortes, MD³

¹School of Public Health, University of Texas Health Science Center, Houston
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, University of Texas MD Anderson Cancer Center, Houston, TX

Moshe Yair Levy, MD¹, Lisa J. McGarry, MPH^2*, Stephanie Lustgarten, PhD^2*, Mo Yang, PhD^2* and Frank G. Haluska, MD²

¹Baylor University Med Center, Dallas, TX
²ARIAD Pharmaceuticals, Inc., Cambridge, MA

Yasmin Abaza, MD^*, Hagop M Kantarjian, MD, Gautam Borthakur, MD, Naval Daver, MD, Farhad Ravandi, MD, Dai Chihara, MD, PhD, Srdan Verstovsek, MD, Jan A Burger, MD, PhD, Zeev Estrov, MD, Maro Ohanian, DO^*, Elias Jabbour and Jorge E. Cortes

Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX

Isabel Amanda Giere, PhD. M.Sc^1*, Marí­a Jose Mela Osorio, MD^1*, Federico Andrés Klosowski^2*, Mariana Debus^2*, Ana Inés Varela, MD^3*, Elena Beatriz Moiraghi, MD^4*, Miguel A Pavlovsky, MD⁵, Isolda Fernandez, MD^1*, Dante Intile, Statistic^1* and Carolina Pavlovsky, MD^6*

¹FUNDALEU, Buenos Aires, Argentina
²Fundaleu, Buenos Aires, Argentina
³Hospital Ramos Mejía / Sanatorio Las Lomas, Buenos Aires, Argentina
⁴HOSPITAL RAMOS MEJIA, Buenos Aires, Argentina
⁵Fundaleu / Centro Hematológico Pavlovsky, Buenos Aires, Argentina
⁶FUNDALEU, Buenos Aires, Argentina, Buenos Aires, Argentina

Michael J. Mauro, MD¹, Lisa J. McGarry, MPH^2*, Mo Yang, PhD^2*, Stephanie Lustgarten, PhD^2* and Hui Huang, MBA, PhD^2*

¹Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
²ARIAD Pharmaceuticals, Inc., Cambridge, MA

Vamsi K Kota, MD¹, Elliott F. Winton, MD¹, Martha Arellano, MD¹, Anand Jillella^1*, Morgan L. McLemore, MD¹, Fuad El Rassi, MD² and H Jean Khoury¹

¹Winship Cancer Institute of Emory University, Atlanta, GA
²The Georgia Comprehensive Sickle Cell Center at Grady Health System, Atlanta, GA

Ching-Yuan Kuo, MD^1*, Po-Nan Wang, MD², Wen Li Hwang, MD^3*, Cheng-Hwai Tzeng, MD^4*, Li-Yuan Bai, MD^5*, Jih-Luh Tang, MD, PhD⁶, Ming-Chih Chang, MD^7*, Sheng-Fung Lin, MD⁸, Tsai-Yun Chen, MD⁹, Yeu-Chin Chen, MD¹⁰, Tran-Der Tan, MD¹¹, Chih-Yi Hseih, MD^12*, Chinjune Lin, MD^13*, Miljkovic Darko, MD^14* and Chang Cheng-Shyong, MD^15*

¹Chang Gung Memorial Foundation-Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
²Chang Gung Memorial Hospital-Linkou, Taoyuan, Taiwan
³Taichung Veterans General Hospital, Taichung City, Taiwan
⁴Division of Hematology/Medical Oncology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
⁵China Medical University Hospital, Taichung, Taiwan
⁶Division of Hematology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
⁷Mackay Memorial Hospital, Taipei, Taiwan
⁸Division of Hematology/Oncology, Department of Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
⁹National Cheng Kung University Hospital, Tainan, Taiwan
¹⁰Tri-Service General Hospital (TSGH), Taipei, Taiwan
¹¹Department Hematology & Medical Oncology, Koo Foundation Sun Yet-Sen Cancer Center, Taipei, Taiwan
¹²Novartis (Taiwan) Co. Ltd., Taipei, Taiwan
¹³Novartis Pharmaceuticals Corporation, East Hanover, NJ
¹⁴Novartis Pharma AG, Basel, Switzerland
¹⁵Changhua Christian Hospital, Changhua city, Taiwan

Tetsuro Ochi^1*, Taiichi Kyo, MD¹, Kayo Toishigawa^1*, Takeshi Okatani^1*, Ryota Imanaka^1*, Kohei Kyo^1*, Mitsuhiro Itagaki^1*, Yuta Katayama^1*, Koji Iwato^2* and Hideki Asaoku^3*

¹Department of Internal Medicine, Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital, Hiroshima, Japan
²Department of Blood Transfusion, Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital, Hiroshima, Japan
³Department of Clinical Laboratory, Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital, Hiroshima, Japan

Sung-Eun Lee^1,2*, Soo Young Choi^2*, Soo-Hyun Kim^2*, Hye-Young Song^2*, Hea-Lyun Yoo^2*, Mi-Young Lee^2*, Ki-Hoon Kang^2*, Hee-Jeong Hwang^2*, Eun-Jung Jang^2* and Dong-Wook Kim^2,3

¹Department of Hematology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, South Korea
²Cancer Research Institute, The Catholic University of Korea, Seoul, South Korea
³Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, South Korea

Lei Chen, MD, PhD^1*, Dominick Latremouille-Viau, MSc^2*, Annie Guerin, MSc^2*, Roy Nitulescu, MSc^2* and Patrick Gagnon-Sanschagrin, BSc^2*

¹Novartis Pharmaceuticals Corporation, East Hanover, NJ
²Analysis Group, Inc., Montreal, QC, Canada

Ester Pungolino, MD^1*, Giuseppe Rossi, MD², Maria Angela Mura^3*, Alessandra Perego, MD^4*, Ester Maria Orlandi, MD^5*, Mauro Turrini, MD^6*, Lorenza Borin, MD^7*, Maria Adele Capucci, MD^2*, Alessandra Iurlo, MD, PhD^8*, Alessandra Trojani, PhD^9*, Mariella D'Adda, MD^2*, Francesco Spina, MD^10*, Gabriella De Canal^3*, Maria Luisa Pioltelli^9*, Maria Luisa Latargia, MD^11*, Sergio Pauli, MD^12*, Chiara Elena, MD^13*, Stefania Brusorio^9*, Francesco Lanza, MD^14*, Simona Malato, MD^15*, Michela Anghilieri, MD^16*, Maria C Carraro, MD^17*, Enrica Morra, MD⁹ and Roberto Cairoli, MD^18*

¹Niguarda Cà Granda Hospital, Milan, Italy
²Division of Hematology, A.O. Spedali Civili of Brescia, Brescia, Italy
³Pathology Department, Cytogenetics, Niguarda Cà Granda Hospital, Milan, Italy
⁴Internal medicine-Haematology, Desio Hospital, Desio, Italy
⁵Dept of Oncology-Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
⁶Division of Hematology, Valduce Hospital, Como, Italy
⁷San Gerardo Hospital, Monza, Italy
⁸Division of Hematology, IRCCS Maggiore Policlinico Hospital Foundation, Milano, Italy
⁹Division of Hematology, Niguarda Cà Granda Hospital, Milan, Italy
¹⁰Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
¹¹Busto Arsizio Hospital, Busto Arsizio, MI, Italy
¹²Azienda Ospedaliera Sant'Antonio Abate, Gallarate, Italy
¹³Policlinico S. Matteo IRCCS, Pavia, Italy
¹⁴Cremona Hospital, Cremona, Italy
¹⁵Hematology and Bone Marrow Transplantation Unit, San Raffaele Scientific Institute, Milano, Italy
¹⁶Manzoni Hospital, Lecco, Italy
¹⁷A.O. Sacco Hospital, Milan, Italy
¹⁸Division of Hematology, Niguarda Ca' Granda Hospital, Milan, Italy

Roberto Latagliata^1*, Massimo Breccia, MD^2*, Dario Ferrero, MD^3*, Francesco Cavazzini⁴, Malgorzata Monika Trawinska^5*, Fausto Castagnetti, MD/PhD⁶, Mario Annunziata, MD^7*, Fabio Stagno, MD/PhD⁸, Mario Tiribelli, MD^9*, Gianni Binotto^10*, Carmen Fava, MD^11*, Elena Crisà, MBBS, MD^12*, Giovanna Mansueto^13*, Antonella Gozzini^14*, Franca Falzetti, MD¹⁵, Enrico Montefusco, MD^16*, Alessandra Iurlo, MD, PhD^17*, Russo Sabina^18*, Michele Cedrone, MD^19*, Antonella Russo Rossi, MD^20*, Gabriele Gugliotta, MD/PhD^6*, Patrizia Pregno, MD^21*, Alessandro Isidori, MD, PhD²², Paolo Avanzini, MD^23*, Mauro Endri^24*, Atelda Romano, MD^25*, Gianfranco Giglio, MD^26*, Francesca Celesti, MD^27*, Federica Sorà, MD, PhD^28*, Sergio Storti, MD²⁹, Ada D'Addosio, MD^30*, Sara Galimberti, MD^31*, Ester Maria Orlandi, MD^32*, Elisabetta Calistri^33*, Monica Bocchia, MD^34*, Monica Crugnola, MD^35*, Giovanna Rege Cambrin^36*, Paolo Vigneri, MD/PhD^37*, Luigiana Luciano, MD³⁸, Elisabetta Abruzzese, MD³⁹ and Giuliana Alimena, MD⁴⁰

¹Dept. of Cellular Biotechnologies and Hematology, Sapienza University, Rome, Rome, Italy
²Dipartimento di Ematologia e Biotecnologie, Università La Sapienza, Rome, Italy
³Chair of Hematology, Department of Medicine and Experimental Oncology, Torino, Italy
⁴Hematology, University of Ferrara, Ferrara, Italy
⁵Hematology, Sant'Eugenio Hospital, Rome, Italy
⁶Institute of Hematology, S.Orsola-Malpighi University Hospital, Bologna, Italy
⁷Hematology, OSPEDALE CARDARELLI, NAPOLI, Italy
⁸Section of Hematology, A.O.U. Policlinico, Catania, Italy
⁹Division of Hematology and BMT, Department of Experimental and Clinical Medical Sciences, Azienda Ospedaliero-Universitaria di Udine, Udine, Italy
¹⁰Department of Medicine, Hematology and Clinical Immunology, Padua School of Medicine, Padova, Italy
¹¹Division of Internal Medicine - Hematology, San Luigi Gonzaga Hospital, University of Turin, Orbassano, Italy
¹²Hematology, University of Turin, Turin, Italy
¹³Hematology, IRCCS - CROB Rionero in Vulture, Rionero in Vulture, Italy
¹⁴Hematology, University of Florence, Florence, Italy
¹⁵University of Perugia, Perugia, Italy
¹⁶Hematology Unity, Sant'Andrea Hospital, Rome, Italy
¹⁷Division of Hematology, IRCCS Maggiore Policlinico Hospital Foundation, Milano, Italy
¹⁸Hematology, University of Messina, Messina, Italy
¹⁹UOC of Hematology, San Giovanni - Addolorata Hospital, Rome, Italy
²⁰Hematology, University of Bari, Bari, Italy
²¹Hematology Unit, AZ OSP. CITTA' DELLA SALUTE E SCIENZA TORINO, TORINO, Italy
²²Hematology, San Salvatore Hospital, Pesaro, Italy
²³Hematology, S.Maria Nuova Hospital, Reggio Emilia, Italy
²⁴Hematology, Santa Maria degli Angeli Hospital, Pordenone, Italy
²⁵Hematology, Regina Elena National Cancer Institute, Rome, Italy
²⁶Hematology, Cardarelli Hospital, Campobasso, Italy
²⁷Hematology, Belcolle Hospital, Viterbo, Italy
²⁸Università Cattolica del Sacro Cuore, Rome, Italy
²⁹UOC di Onco-Ematologia, Università Cattolica del Sacro Cuore - Centro di Ricerca e Formazione ad Alta Tecnologia nelle Scienze Biomediche, Campobasso, Italy
³⁰Hematology, Villa San Pietro Hospital, Rome, Italy
³¹UO University Hematology, AOU Pisana, Pisa, Italy
³²Dept of Oncology-Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
³³Hematology Unit, Ospedale Ca' Foncello, Treviso, Treviso, Italy
³⁴Department of Hematology and Transplants, University of Siena, Siena, Italy
³⁵Clinical and Experimental Medicine, University of Parma, Parma, Italy
³⁶University of Turin, ORBASSANO TORINO, Italy
³⁷Dep. Clinical and Experimental Medicine, University of Catania Medical School, Catania, Italy
³⁸Department of Hematology, Federico II University, Naples, Italy
³⁹Hematology, S. Eugenio Hospital, Roma, Italy
⁴⁰Department of Biotechnologies and Hematology, Sapienza University, Rome, Italy