Vikram R Paralkar, MD¹, Cristian Taborda^2*, Yu Yao, MD^3*, Rishi Prasad^2*, Jing Luan^2*, Ross C. Hardison, PhD^4*, Gerd A. Blobel, MD, PhD⁵ and Mitchell J Weiss, MD, PhD^3*

¹Division of Hematology/Oncology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA
²Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA
³Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN
⁴Penn State University, State College, PA
⁵Division of Hematology, The Children's Hospital of Philadelphia, Philadelphia, PA

Xin Gao¹, Tongyu Wu^1*, Jamie Lahvic^2*, Kirby D. Johnson^1*, Erik A. Ranheim, MD³, Leonard I. Zon, M.D^2,4 and Emery H Bresnick, Ph.D.¹

¹Department of Cell and Regenerative Biology, Carbone Cancer Center, UW-Madison Blood Research Program, University of Wisconsin School of Medicine and Public Health, Madison, WI
²Stem Cell Program and Division of Hematology/Oncology, Howard Hughes Medical Institute, Boston Children's Hospital/Harvard Medical School, Boston, MA
³Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI
⁴Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA

Yue Gu, MS^1*, Wei Yang, PhD^2*, Amanda Jones, PhD^3*, Shanrun Liu, MD, PhD^4*, Qian Dai, MD, PhD^5*, C Scott Swindle, PhD^6*, Thomas Ryan, PhD^4*, Tim M. Townes, PhD⁷, Christopher Klug, PhD⁸ and Hengbin Wang, PhD^1*

¹Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL
²Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, Birmingham, AL
³Department of Biochemistry and Molecular Genetics, 1Department of Biochemistry and Molecular Genetics, Birmingham, AL
⁴University of Alabama at Birmingham, Birmingham, AL
⁵Department of Pathology, University of Alabama at Birmingham, Birmingham, AL
⁶Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL
⁷Department of Biochemistry and Molecular Genetics, UAB Stem Cell Institute, University of Alabama at Birmingham, Birmingham, AL
⁸The Univ. of AL at Birmingham, Birmingham, AL

Alan D. Friedman, M.D., Hong Guo, MD, PhD^* and Stacy Cooper, MD^*

Division of Pediatric Oncology, Johns Hopkins University School of Medicine, Baltimore, MD

Zhongfa Yang, PhD^1*, Yu Zhu, MD, PhD¹, Rachel Gerstein, PhD² and Alan G. Rosmarin, MD¹

¹Medicine, University of Massachusetts Medical School, Worcester, MA
²Microbiology and Physiological Systems, UMASS Medical School, Worcester, MA

M Cristina Keightley, PhD^1*, Duncan P. Carradice, MBBS, FRCPA, FRACP², Joly Kwek, PhD^1*, Ashley Buckle, PhD^3*, Judith E Layton, PhD^2*, Joan K Heath, D.Phil^2* and Graham J Lieschke, PhD, MBBS, BMedSc, FRACP¹

¹Australian Regenerative Medicine Institute, Monash University, Clayton, Australia
²The Walter & Eliza Hall Institute of Medical Research, Parkville, Australia
³Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia

Pierre-Jacques Hamard, Ph.D.¹, Luisa Luciani, Ph.D.^2*, Fan Liu, Ph.D.^2*, Guoyan Cheng, Ph.D.^2*, Megan A. Hatlen, Ph.D.^3*, Olga A Guryanova, M.D., Ph.D.^4*, Xinyang Zhao, Ph.D.⁵, Ross L. Levine, MD^6,7 and Stephen D. Nimer, MD⁸

¹Sylvester Comprehensive Cancer Center, Miami, FL
²Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL
³Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY
⁴Memorial Sloan-Kettering Cancer Center, New York, NY
⁵UAB Stem Cell Institute, Department of Biochemistry and Molecular Genetics, The University of Alabama at Birmingham, Birmingham, AL
⁶Memorial Sloan Kettering Cancer Center, New York, NY
⁷Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁸Sylvester Comprehensive Cancer Center, Department of Medicine, Miller School of Medicine, University of Miami, Miami, FL

Sung Kai Chiu, MBBS^1,2*, Cedric Tremblay, PhD^1*, Jesslyn Saw^1* and David J. Curtis, M.D., Ph.D.^1,2

¹Australian Centre For Blood Diseases, Monash University, Melbourne, Australia
²Department of Haematology, The Alfred Hospital, Melbourne, Australia

Omer Schwartzman^1*, Zohar Mukamel, PhD^2*, Shai Izraeli, MD, Prof^3,4 and Amos Tanay, PhD, Prof^2*

¹Tel Aviv University, Sheba Medical Center, Tel Aviv, Israel
²Department of Biological Regulation and Computer Science and Applied Mathematics, Weizmann Institute of Science, Rehovot, Israel
³Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⁴Sheba Medical Center, Edmond and Lily Safra Children Hospital, Pediatric Hematology Oncology, Tel Hashomer, Ramat Gan and Tel Aviv University, Ramat Gan, Israel