Manisha Du Plessis^1*, Luis Daniel Mata Casimiro^2*, Irmela Jeremias, MD^3,4 and Olaf Heidenreich, PhD^2,5,6

¹Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands
²Princes Máxima Center for Pediatric Oncology, Utrecht, Netherlands
³Research Unit Apoptosis in Hematopoietic Stem Cells, Helmholtz Munich, German Research Center for Environmental Health (HMGU), Munich, Germany
⁴German Cancer Consortium (DKTK), partner site Munich, a partnership between DKFZ and the Hospital of the Ludwig-Maximilians-University (LMU), Munich, Germany
⁵Wolfson Childhood Cancer Research Centre, Newcastle University, Newcastle upon Tyne, United Kingdom
⁶University Medical Center Utrecht, Utrecht, Netherlands

Justin Adeyeye^1*, Cynthia R. Giver, PhD², Jamie Cohen^3*, Yuou Wang, PhD^3*, Tysheena P. Charles, PhD^4*, Khue G. Nguyen, PhD^5*, Jian-Ming Li, PhD^3*, Jens Wrammert, PhD^4*, David A. Zaharoff, PhD^5* and Edmund K. Waller, MD, PhD⁶

¹Winship Cancer Institute Summer Scholars Research Program, Emory University, Atlanta, GA
²Emory University Winship Cancer Institute, Atlanta, GA
³Winship Cancer Institute, Emory University, Atlanta, GA
⁴Department of Pediatrics, Emory University, Atlanta, GA
⁵Department of Biomedical Engineering, North Carolina State University, Raleigh, NC
⁶Emory University, Winship Cancer Institute, Atlanta, GA

Jeffrey N Lindquist, PhD^1*, Kai Qin, PhD^2*, Jeffrey M Liu, PhD^3*, Aaron M Ring, MD, PhD^2* and Hirdesh Uppal, PhD^1*

¹Simcha Therapeutics, San Francisco, CA
²Fred Hutchinson Cancer Center, Seattle, WA
³Simcha Therapeutics, New Haven, CA

Darren C Phillips, PhD, BSc^*, Luzivette Robles-Cardona^*, Cory Alvey^*, Justin Ingram^*, Lloyd T Lam, PhD^*, Ziping Yang^*, Jacob J Riehm, MS^*, Jun Chen, MD, PhD^*, Matthew Kurnick^*, Peter Kovar^*, Jin Wang^*, George Doherty^*, Vikram Bhat^*, Yujia Dai^*, Andrew Judd^* and Andrew Souers, PhD

AbbVie Inc., North Chicago, IL

Timo Ullrich^1*, Birte Hernandez Alvarez^2*, Christoph Pollmann^3*, Malte Ulrich Ritter^4*, Jérémy Haaf^5*, Narges Aghaallaei, PhD^6*, Jacob Piehler^7*, Ivan Tesakov, MD^8*, Maya El-Riz^9*, Kateryna Maksymenko^1*, Valeriia Hatskovska^5*, Sergey Kandabarau^10*, Maksim Klimiankou, PhD^11*, Claudia Lengerke, MD¹², Karl Welte, MD, PhD¹³, Andrei Lupas, PhD^1*, Julia Skokowa, MD, PhD¹¹ and Mohammad ElGamacy, PhD^14*

¹Department Protein Evolution, Max Planck Institute for Biology, Tuebingen, DEU
²Department Protein Evolution, Max Planck Institute for Biology, Tuebingen, Germany
³Department of Biology/Chemistry and Center for Cellular Nanoanalytics, Osnabrück University, Osnabrück, Germany
⁴Department of Oncology, Hematology, Clinical Immunology, and Rheumatology, University Hospital Tuebingen, Tuebingen, BW, Germany
⁵Department of Oncology, Hematology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tuebingen, DEU
⁶University Hospital Tübingen, Tübingen, DEU
⁷Department of Biology/Chemistry and Center for Cellular Nanoanalytics, University of Osnabruck, Osnabruck, DEU
⁸Department of Oncology, Hematology, Immunology, Rheumatology and Clinical Immunology, University Hospital Tübingen, Tübingen, DEU
⁹Department of Biology/Chemistry and Center for Cellular Nanoanalytics, Osnabrück University, OsnabrüCk, DEU
¹⁰Department of Oncology, Hematology, Clinical Immunology, and Rheumatology, University Hospital Tuebingen, Tuebingen, Germany
¹¹Department of Oncology, Hematology, Immunology, Rheumatology and Clinical Immunology, University Hospital Tübingen, Tübingen, Germany
¹²Department for Internal Medicine II, Hematology, Oncology, Clinical Immunology and Rheumatology, University Hospital Tuebingen, Tuebingen, Germany
¹³Pediatric Hematology and Oncology, The University Children's Hospital Tuebingen, Tuebingen, Germany
¹⁴Department of Oncology, Hematology, Clinical Immunology, and Rheumatology, University Hospital Tuebingen, Tuebingen, DEU

Maura Lima Pereira Bueno^1*, Charles Ayemoba^2*, Anna M Di Staulo^2*, Sen Zhang, PhD^2*, Fernanda Soares Niemann, MSc^1*, Nádia Ghinelli Amôr, PhD^1*, Irene Santos, MSc^1*, Adriana da Silva Santos Duarte, PhD^1*, Audrey Bastos^1*, Sara Teresinha Olalla Saad, MD PhD¹, Sandra Pinho, PhD² and Fernanda Marconi Roversi, PhD^1,3*

¹Hematology and Transfusion Medicine Center, State University of Campinas – UNICAMP, Campinas, Brazil
²Department of Pharmacology & Regenerative Medicine, University of Illinois at Chicago, Chicago, IL
³Department of Surgery, Emory University, Atlanta

Neeraj K Aryal, PhD^1*, Thomas Frost, PhD^1*, Yuhan Huang^1*, Bo Kyung Alex Seong, PhD^1*, Lisa Drew, PhD^1* and Omid Tavana^2*

¹AstraZeneca, Waltham, MA
²AstraZeneca Early Oncology R&D TDE, Waltham, MA

Yupeng Zheng, Ph.D.^1*, Walter F Lenoir, Ph.D.^1*, Marek J Kobylarz, Ph.D.^2*, Jun Li^1*, Tamara D Hopkins, PhD^2*, Michael R McKeown, PhD^2*, Michelle G. Shum^2*, Kameron R Mori^2*, Elizabeth C Townsend, Ph.D.^1*, Benjamin W Trotter, Ph.D.^2*, Peter B Rahl, Ph.D.^2*, Nikolaus D Obholzer, PhD^2* and Charles Y Lin, PhD²

¹Kronos Bio, cambridge, MA
²Kronos Bio, Inc., Cambridge, MA

Sarada Ketharnathan, PhD¹, Serkan Dogan^1*, Sujata Pokharel^1*, Sergey V Prykhozhij, PhD^1*, Anna Cordeiro, PhD^2*, Irina Alecu^3*, William Mannherz, PhD⁴, Mira Liebman, MD^5*, Elaine W. Leung, MD, FRCPC⁵, Steffany Bennett^3*, Miroslava Cuperlovic-Culf^6*, Suneet Agarwal, MD, PhD⁴, Yigal Dror, MD, FRCPC⁷ and Jason N. Berman, MD¹

¹CHEO Research Institute, Ottawa, ON, Canada
²AGADA Biosciences, Halifax, NS, Canada
³Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, CAN
⁴Boston Children's Hospital, Boston, MA
⁵Children's Hospital of Eastern Ontario, Ottawa, ON, CAN
⁶Digital Technologies Research Centre, National Research Council of Canada, Ottawa, ON, CAN
⁷Marrow Failure and Myelodysplasia Program, Division of Haematology and Oncology, The Hospital for Sick Children, Toronto, ON, Canada