Carmen Gonzalez, MSc^1*, Catia Simoes, PhD^1*, Leire Burgos, PhD^1*, David Martinez-Cuadron, PhD², Sarai Sarvide^1*, Diego Alignani, PhD^1*, Aitziber Lopez^1*, Yujuan Gui, PhD^3*, Hana Komic, PhD^4*, Tessa Schmachtel, MSc^5*, Carmen Botella, MD, PhD^6*, Raimundo Garcia Boyero, MD^7*, Esther Perez Santaolla, MD^8*, Cristina Gil, MD^9*, Jesús Lorenzo Algarra, MD^10*, Maria Jose Sayas Lloris, MD^11*, Francisco Ibañez, MD^12*, Laura Torres, MD^13*, Isabel Cano-Ferri, MD^2*, Evelyn Acuña-Cruz, MD^13*, Olga Arce, MD^14*, Fredrik B. Thorén, PhD^4*, Michael A. Rieger, PhD^5*, Jesús F. San-Miguel, MD, PhD¹, Felipe Prosper, MD, PhD¹, Pau Montesinos, PhD, MD^2* and Bruno Paiva, PhD^1*

¹Clínica Universidad de Navarra, Centro de Investigación Médica Aplicada, Universidad de Navarra, CCUN, IDISNA, CIBER-ONC, Pamplona, Spain
²Hospital Universitari i Politècnic La Fe, Department of Hematology, Valencia, Spain
³Single-Cell Multiomics, BD Biosciences, Vianen, Netherlands
⁴TIMM Laboratory at Sahlgrenska Center for Cancer Research, Institute of Biomedicine, University of Gothenburg, Gothenburg, Sweden
⁵Department of Medicine 2, Hematology/Oncology, Goethe University Hospital Frankfurt, Frankfurt, Germany
⁶Department of Hematology, Hospital General Universitario De Alicante, Alicante, Spain
⁷Hospital General Universitario de Castellon, Castellon, Spain
⁸Hospital Donostia, Donostia, Spain
⁹Hospital General Universitario De Alicante, Alicante, Spain
¹⁰Hospital General de Albacete, Albacete, Spain
¹¹Hospital Dr. Peset, Valencia, Spain
¹²Hospital General Universitario de Valencia, Valencia, Spain
¹³Hospital Universitary i Politecnic La Fe, Valencia, Spain
¹⁴Hospital Universitario de Basurto, Bilbao, Spain

Lukas H. Haaksma, MD^1,2*, Raffaele Palmieri^3*, Jesse M. Tettero, MD, PhD^1,2*, Tom Reuvekamp^1,2,4*, Lok Lam Ngai, MD^1,2*, Costa Bachas, PhD^1,2*, Angèle Kelder^1,2*, Willemijn J. Scholten^1,2*, Patrycja Gradowska, PhD^5,6*, Valentina Arena^7*, Anderson Simione^8*, Luca Maurillo, MD^3*, Adriano Venditti³, Bob Lowenberg, MD, PhD⁶, Gert J. Ossenkoppele, MD, PhD^1,2, David C. de Leeuw, MD, PhD^1,2*, Maura R. V. Ikoma-Colturato, MD, PhD^8*, Francesco Buccisano, MD³ and Jacqueline Cloos, PhD^1,2*

¹Department of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands
²Imaging and Biomarkers, Cancer Center Amsterdam, Amsterdam, Netherlands
³Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy
⁴Department of Hematology, Amsterdam UMC location Universiteit van Amsterdam, Amsterdam, Netherlands
⁵HOVON Foundation, Rotterdam, Netherlands
⁶Department of Hematology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, Netherlands
⁷GIMEMA Foundation, Rome, Italy
⁸Flow Cytometry Laboratory, Hospital Amaral Carvalho, Jaú, Brazil

Morgan L Shannon, MD^1*, Tian Y Zhang, MD, PhD^2,3, Lori Muffly, MD⁴ and Gabriel N Mannis, MD^2,3

¹Stanford Health Care, Stanford, CA
²Division of Hematology, Department of Medicine, Stanford Health Care, Stanford, CA
³Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA
⁴Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Stanford, CA

Zhong Zhang^1*, Miriam Wilhelm^1*, Ines Sieber^1*, Hartmut Döhner, MD¹ and Michaela Feuring, md^2*

¹Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
²Ulm University Hospital, Ulm, Germany

David Sallman, MD¹, Amy F McLemore, MS^2*, Onyee Chan, MD³, Andrew T. Kuykendall, MD¹, Eric Padron, MD¹, Zhuoer Xie, MD, MS³, Alison R. Walker, MD, MBA, MPH⁴, David H Spencer, MD, PhD⁵, Rami S. Komrokji, MD³, Jeffrey E Lancet, MD¹ and Meagan Jacoby, MD⁶

¹Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
²Malignant Hematology Department, Moffitt Cancer Center, Tampa, FL
³Department of Malignant Hematology, Moffitt Cancer Center, Tampa, FL
⁴Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Wesley Chapel, FL
⁵Division of Oncology, Department of Medicine, Washington University School of Medicine in St. Louis, St Louis, MO
⁶Washington University-School of Medicine, Richmond Heights, MO

Katarina Micin, BS, MS^1*, Tiffany Nong^1*, Ellen Madarang, PharmD^2*, Kiana Robles^2*, Maurizio Affer, MS^1*, Brittney Otero, PhD^3*, Azad Gucwa^3*, Felipe Novoa^2*, Sion Williams^4*, Ana Ayupe^5*, Yi Zhou^6*, Justin M. Watts, MD² and Justin Taylor, MD^1,2

¹Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL
²Leukemia Service, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL
³Mission Bio, San Francisco, CA
⁴Onco-Genomics Shared Resource, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL
⁵Onco-Genomics Shared Resource, Sylvester Comprehensive Cancer Center, University of Miami Miller of School of Medicine, Miami, FL
⁶Molecular Diagnostics Lab, Department of Pathology, University of Miami Miller School of Medicine, Miami, FL

Jacob Jendro^1*, Lara Bischof, MD^1*, Jule Ussmann, MD^1*, Tung Pham Thanh^1*, Donata Backhaus, MD^1*, Dominic Brauer, MD^1*, Vladan Vucinic, MD^1*, Carmen Herling, MD^1*, Marco Herling, MD^1*, Georg-Nikolaus Franke, MD^1*, Maximilian Merz, MD¹, Klaus H Metzeler, MD¹, Uwe Platzbecker, MD¹, Sebastian Schwind, MD^1* and Madlen Jentzsch, MD^2*

¹Department for Hematology, Cell Therapy, Hemostaseology and Infectious Diseases, University of Leipzig Medical Center, Leipzig, Germany
²Department for Hematology, Cell Therapy, Hemostaseology and Infectious Diseases, University of Leipzig Medical Center, Leipzig, Sachsen, Germany

Martin Carre, MD^1*, Mathieu Meunier^2*, Zofia Gross, MD^3*, Gaspar Aspas Requena^4*, Urbain Tauveron-Jalenques^5*, Emmanuelle Tavernier, MD^6*, Jérome Cornillon, MD^7*, Ugo Thévenet, MD^8*, Boullanger Fow Heng Nadine^9*, Clémence Santana^10*, Clément Rocher, MD^11*, Sylvain Lamure, MD, PhD^12*, Amine Belhabri, MD^13*, Mauricette Michallet, MD, PhD¹³, Adrien Contejean^14*, Natacha Mauz^14*, Gian Matteo Pica, MD^15*, Arthur Dony^15* and Mael Heiblig^16*

¹Clinical Hematology Department, CHU Grenoble Alpes - Université Grenoble Alpes, Grenoble, France
²Department of Hematology CHU Grenoble Alpes, Grenoble, France
³Département d'Hématologie, CHU de Lyon, Pierre-Bénite, France
⁴CHU Clermont-Ferrand, Clermont-Ferrand, France
⁵Service d'Hématologie Clinique et Thérapie Cellulaire, CHU Clermont-Ferrand, Clermont-Ferrand, France
⁶Institut De Cancérologie De La Loire, Saint Priest En Jarez, FRA
⁷Institut Cancerologique De La Loire, Saint-priest-en-Jarez, FRA
⁸Département d'hématologie Clinique et de Thérapie Cellulaire, CHU Saint-Etienne, Saint-Etienne, France
⁹CH de Roanne, Roanne, France
¹⁰Département d'Hématologie, CH de Valence, Valence, France
¹¹Département d'Hématologie, Centre Hospitalier Bourgoin Jallieu, Bourgoin Jallieu, France
¹²Département d'Onco-Hématologie, Hôpitaux Nord-Ouest, Villefranche-sur-Saone, France
¹³Département de Cancérologie médicale, Centre Léon Bérard, Lyon, France
¹⁴Département d'Hématologie, Centre Hospitalier Annecy Genevois, Epagny Metz-Tessy, France
¹⁵Département d'Hématologie, CH Chambery, Chambéry, France
¹⁶Service d'hématologie clinique, Hospices Civils de Lyon, Hôpital Lyon Sud, Pierre-Bénite, France

Sanam Loghavi, MD^1*, Sa A. Wang, MD², Wei-Ying Jen, MD, FRCPath, MA^3,4*, Wei Wang, MD, PhD^5*, Hong Fang^5*, Shaoying Li, MD⁶, Sofia A. Garces, MD^7*, Andres E Quesada, MD^8*, Jie Xu, MD PhD^2*, Chi Young Ok, MD⁶, Shimin Hu^9*, Jeffrey L. Jorgensen, MD², Guilin Tang, MD, PhD^2*, Cedric Nasnas, MD^4*, Omer Karrar^10*, Ghayas C. Issa, MD⁴, Naval Daver, MD¹¹, Courtney D. DiNardo, MD, MSc¹², Tapan M. Kadia, MD⁴, Hagop M. Kantarjian, MD⁴, L. Jeffrey Medeiros, MD², Farhad Ravandi, MBBS¹³ and Nicholas J. Short, MD⁴

¹Department of Hematopathology, MD Anderson Cancer Center, Houston, TX
²Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Haematology-Oncology, National University Cancer Institute, Houston, TX
⁴Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Hematopathology, The University of Texas, MD Anderson Cancer Center, Houston, TX
⁶Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷Hematopathology, MD Anderson Cancer Center, HOUSTON, TX
⁸Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX
⁹Department of Hematopathology, The University of Texas M.D. Anderson Cancer Center, Houston, TX
¹⁰The University of Texas MD Anderson Cancer Center, Houston, TX
¹¹MD Anderson Cancer Center, Houston, TX
¹²Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
¹³Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX

Enise Ceran, MD^1*, Anne Kathrin Merbach, PhD^1,2*, Christian Rohde, PhD^1,2*, Robert Durruthy-Durruthy, PhD^3*, Adam Sciambi, PhD^3*, Michelle Lotze^1*, Gema Fuerte, PhD^3*, Matteo Cattaneo, PhD^3*, Ivan Lukic, PhD^3*, Maxi Wass, MD^4*, Judith Schaffrath, MD^4*, Christoph Röllig, MD, MSc^5*, Richard F. Schlenk, MD^1*, Marina Scheller, PhD^1*, Simone Kowoll^6*, Jörg Steighardt, PhD^6*, Bayram Edemir, MD^4*, Beatrice Ludwig-Kraus, MD^7*, Lutz P. Mueller, MD^4*, Sabine Edemir^4*, Abi Vainstein-Haras, MD^8*, Ella Sorani, PhD^8*, Irit Gliko Kabir, PhD^8*, Shaul Kadosh, PhD^8*, Cora Gromann^6*, Andreas Wienke, PhD^9*, Claudia Wickenhauser, MD^10*, Claudia D Baldus, MD^11*, Uwe Platzbecker, MD¹², Hubert Serve, MD¹³, Martin Bornhäuser, MD^14* and Carsten Müller-Tidow, MD^1,2*

¹Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany
²European Molecular Biology Lab (EMBL), Molecular Medicine Partnership Unit, Heidelberg, Germany
³Mission Bio, South San Francisco, CA
⁴Department of Internal Medicine IV, Hematology and Oncology, Martin Luther University Halle-Wittenberg, Halle, Germany
⁵Department of Internal Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany
⁶Coordination Centre for Clinical Trials Halle, Martin-Luther University Halle-Wittenberg, Halle, Germany
⁷Department of Laboratory Medicine, Martin Luther University Halle-Wittenberg, Halle, Germany
⁸BiolineRx, Modi'in, Israel
⁹Institute of Medical Epidemiology Biometrics and Informatics, Martin Luther University Halle-Wittenberg, Halle, Germany
¹⁰Department of Pathology, Martin Luther University Halle-Wittenberg, Halle, Germany
¹¹Department of Hematology and Oncology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany
¹²Department of Hematology, Cellular Therapy, Hemostaseology and Infectious Diseases, University Leipzig Medical Center, Leipzig, Germany
¹³Department of Medicine, Hematology/Oncology, Goethe-University Frankfurt, University Hospital, Frankfurt am Main, Germany
¹⁴National Center for Tumor Diseases (NCT/UCC) Dresden, Technical University Dresden, Dresden, Germany