-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

605. Molecular Pharmacology and Drug Resistance: Lymphoid Neoplasms: Poster III

Symposia: Molecular Pharmacology and Drug Resistance: Lymphoid Neoplasms Program: Oral and Poster Abstracts
Type: Poster
Monday, December 9, 2024: 6:00 PM-8:00 PM
Halls G-H (San Diego Convention Center)

Maija Garnaas1*, Kristen Cowens1*, Zhen Zhang, PhD1*, Michael Deci2*, Maiko Obana, PhD1*, John Zielinski2*, Matthew Sullivan2*, Russell Karp2*, Stephanie Christainsen2*, Brianna Magliozzi2*, Graham MacLean1*, Terrence Washington2*, Ying Fu2*, Varun Chavada2*, Hannah D'Ambrosio2*, Sunil Singh2*, John Eldredge1*, Kenneth Drombosky, PhD2*, Pradeep Babu Jagadeesh Reddy2*, Shilpa Sharma2*, Harkewal Singh2*, Neeraj Kaushal, PhD2*, Binu Philip2*, Graham Farrington, PhD2*, Brendan M. Weiss, MD1, Joshua P Frederick, PhD2* and Lin Guey2*

1Moderna, Inc., Cambridge, MA
2ModernaTX, Inc., Cambridge

Mark E Robinson, PhD1*, Qin Li, PhD1*, Chang Zhang, PhD1*, Chuanzong Zhan, PhD1*, Zhangliang Cheng, BSc1*, Kohei Kume, PhD1*, Kadriye Nehir Cosgun, PhD1*, Shalin Kothari, MD1*, Nikol Agadzhanian, MSc1*, Daisuke Nakada, PhD2 and Markus Müschen, MD1

1Center of Molecular and Cellular Oncology, Yale University, New Haven, CT
2Department of Molecular & Human Genetics, Baylor College of Medicine, Houston, TX

Li Wang, MD1,2,3*, Guo Zhang, PhD2*, Hui Zhou, MD1,2,3* and Ting Niu, MD, PhD2,3,4

1Department of Hematology, West China Hospital, Sichuan University, Chengdu, China
2State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University, Chengdu, China
3National Facility for Translational Medicine (Sichuan), West China Hospital, Sichuan University, Chengdu, China
4Department of Hematology, West China Hospital, Sichuan University, Chengdu, Sichuan, China

Mayu Tomita1*, Natsumi Kawasaki, PhD1*, Keigo Yorozu, PhD1*, Mitsue Kurasawa1*, Bansho Masutani, PhD2*, Nicolas Sax, MS2*, Sei Shu, PhD1*, Yoriko Yamashita-Kashima, PhD1* and Shigeki Yoshiura, PhD1*

1Product Research Dept., Chugai Pharmaceutical Co., Ltd., Yokohama, Kanagawa, Japan
2Biological Technology Dept., Chugai Pharmaceutical Co., Ltd., Yokohama, Kanagawa, Japan

Paola Manara, MS1, Venu Venkatarame Gowda Saralamma, PhD2*, Austin Daniel Newsam, BS1*, Marco Vincenzo Russo, PhD3*, Tyler Andrew Cunningham, PhD4*, Alicia Bilbao Martinez, BS3*, Nikolai Fattakhov, PhD3*, Kyle Hoffman, PhD5*, Alexandra Marie Carbone, BS1*, Abdessamad Youssfi Alaoui, PhD2*, Dhanvantri Chahar, PhD2*, Olivia Barbara Lightfuss, BS1*, Francesco Maura, MD6, Daniel Bilbao, PhD3 and Jonathan H. Schatz, MD2

1University of Miami Miller School of Medicine Sheila and David Fuente Graduate Program in Cancer Biology, Miami, FL
2Division of Hematology, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL
3Department of Pathology and Laboratory Medicine, University of Miami Miller School of Medicine, Miami, FL
4University of Miami Miller School of Medicine Medical Scientist Training Program, Miami, FL
5Bioinformatics Solutions Inc, Waterloo, ON, Canada
6University of Miami, Coral Gables, FL

Ting Shi1*, Jin Peng2*, Wei Yuan3*, Xinghua Zhen2*, Jieyu Xu, MD4*, Wen Gao5, Pumin Zhang2* and Honghu Zhu1,6*

1Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
2Zhejiang Provincial Key Laboratory of Pancreatic Diseases, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
3Hematology, Affiliated Hospital of Jiujiang University, Jiujiang, China
4Department of Lymphoma, Zhejiang Cancer Hospital, Hangzhou, China
5Department of Hematology, Beijing Chao-Yang Hospital, Capital Medical University, Beijing, China
6Chinese Institutes for Medical Research, Beijing, China

Kristopher Adrian Knight1, Harrison C. Brown, PhD2*, Mathew S. Karpen3*, H. Trent Spencer, PhD3*, Christopher B. Doering, PhD4* and Sunil S Raikar, M.D.3

1Molecular and Systems Pharmacology, Emory University, Atlanta, GA
2Expression Therapeutics, Tucker, GA
3Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Emory University and Children's Healthcare of Atlanta, Atlanta, GA
4Aflac Cancer and Blood Disorders Center, Emory University and Children's Healthcare of Atlanta, Atlanta, GA

Jacinta Davis, PhD1, JuanCarlos Balandrán, PhD2*, Katharina Hayer, MS1,3*, Sisi Zheng, MD1,4,5, Zhiwei Ang, PhD1*, Evelyn Liu1,6*, Bonnie Yates, NP7*, Nirali N. Shah, MD8, Iannis Aifantis, PhD2 and Andrei Thomas-Tikhonenko, PhD1,5,9

1Division of Cancer Pathobiology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Philadelphia, PA
2Department of Pathology and Laura & Isaac Perlmutter Cancer Center, NYU School of Medicine, New York, NY
3Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA
4UT Southwestern, Dallas, TX
5Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA
6Department of Biology, University of Pennsylvania, Philadelphia, PA
7Pediatric Oncology Branch, National Institutes of Health, Bethesda, MD
8Pediatric Oncology Branch, NIH, Bethesda, MD
9Department of Pathology & Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

Natsumi Kawasaki, PhD*, Sei Shu, PhD*, Xiaoxiao Liu, PhD* and Shigeki Yoshiura, PhD*

Product Research Dept., Chugai Pharmaceutical Co., Ltd., Yokohama, Kanagawa, Japan

Jason Yongsheng Chan1, Elizabeth Chun Yong Lee2*, Kelila Xin Ye Chai2*, Boon Yee Lim2*, Zhimei Li2*, Jing Yi Lee3*, Bavani Kannan2*, Tun Kiat Ko2*, Jessica Sook-Ting Kok3*, Kah Suan Lim3*, Nur Ayuni Muhammad Taib2*, Dachuan Huang, PhD, BSc, MSc4*, Jing Quan Lim, PhD3*, Masatoshi Hazama5*, Koji Fukushima6*, Bin Tean Teh3*, Soon Thye Lim1* and Choon Kiat Ong7*

1Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
2National Cancer Centre Singapore, Singapore, SGP
3National Cancer Centre Singapore, Singapore, Singapore
4National Cancer Centre Singapore, SINGAPORE, Singapore
5SymBio Pharmaceuticals Limited, Minato-Ku, TKY, Japan
6SymBio Pharmaceuticals Limited, Tokyo, Japan
7National Cancer Centre Singapore, Singapore, Singapore, SGP

Steffen Krohn1*, Carina Lynn Gehlert, PhD1*, Dorothee Winterberg, PhD1*, Alexander Jochimsen1*, Ammelie Svea Boje1*, Natalie Baum, PhD1*, Claudia D Baldus, MD2,3*, Monika Brüggemann, MD2,3*, Gunnar Cario, MD3,4*, Martin Schrappe, MD3,4, Lennart Lenk, PhD3,4*, Martin Gramatzki, MD1, Katja Klausz, PhD1,3*, Christian Kellner, PhD5* and Matthias Peipp, PhD1,3*

1Division of Antibody-Based Immunotherapy, Department of Hematology and Oncology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany
2Department of Hematology and Oncology, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany
3Clinical Research Unit CATCH ALL (KFO 5010/1) funded by the Deutsche Forschungsgemeinschaft, Kiel, Germany
4Department of Pediatrics I, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany
5Division of Transfusion Medicine, Cell Therapeutics and Haemostaseology, LMU University Hospital, LMU Munich, Munich, Germany

Yidan Zhang1*, Xiyue Xu1*, Xianhuo Wang, MD1* and Huilai Zhang, MD2

1Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
2Tianjin Medical University Cancer Institute and Hospital, Tianjin, Tianjin, China

Ningjing Lin, MD1*, Tingting Du, MA1*, Hui Zhou2*, Yajun Li, MD2*, Liang Wang3*, Xiaomeng Dong, PhD4*, Haochuan Zheng, PharmD4*, Jingtao Lu, PhD4*, Mi Tang, PhD4*, Jihua Wu, PhD4*, Wei Zhu, MD4*, Yuqin Song, MD5 and Jun Zhu, PhD6

1Department of Lymphoma, Peking University Cancer Hospital and Institute, Beijing, China
2Hunan Cancer Hospital, Changsha, China
3Beijing Tongren Hospital, Beijing, China
4BioRay Pharmaceutical Co., Ltd, Taizhou, China
5Key Laboratory of Carcinogenesis and Translational Research, Department of Lymphoma, Peking University Cancer Hospital, Beijing, China
6Department of Lymphoma, Peking University Cancer Hospital, Beijing, Beijing, China

Yingying Zuo, PhD1*, Yun Liu, PhD1*, Meng Chen1*, Yixin Ai2*, Yanxia Shi, PhD3*, Jingrong Cao, PhD4 and Yihan Wang, PhD4*

1Department of Preclinical Management, Shenzhen TargetRx, Inc., Shenzhen, China
2Department of Computational Chemistry, Shenzhen TargetRx, Inc., Shenzhen, China
3Department of Biological and Translational Research, Shenzhen TargetRx, Inc., Shenzhen, China
4Shenzhen TargetRx, Inc., Shenzhen, China

Jessica A.O. Zimmerman, MD, MS1,2, Mimi Fang, MS2,3*, Dawne Shelton, PhD4* and Miles A. Pufall, PhD2,3*

1Stead Family Department of Pediatrics - Hematology/Oncology, University of Iowa, North Liberty, IA
2Holden Comprehensive Cancer Center, University of Iowa, Iowa City, IA
3Department of Biochemistry and Molecular Biology, University of Iowa, Iowa City, IA
4Illumina, San Diego

Haruya Okamoto, MD1*, Shinsuke Mizutani, MD, PhD1*, Taku Tsukamoto, MD, PhD1*, Yoko Katsuragawa-Taminishi, MD1*, Yuka Kawaji-Kanayama1*, Kentaro Mizuhara, MD1*, Ayako Muramatsu, MD, PhD1*, Reiko Isa, MD, PhD1*, Takahiro Fujino, MD, PhD1*, Yuji Shimura, MD, PhD1*, Koji Ichikawa2* and Junya Kuroda, MD, PhD3

1Division of Hematology and Oncology, Kyoto Prefectural University of Medicine, Kyoto, Japan
2Taiho Pharmaceutical Co., Ltd., Tsukuba, JPN
3Division of Hematology and Oncology, Department of Medicine,, Kyoto Prefectural University of Medicine, Kyoto, Japan

Kyla L. Trkulja1,2, Will Tong2*, Daisy V. Tran2*, Li Meng2*, Evelyn Teh, PhD3*, Susanne Penny, PhD3*, Devanand M. Pinto, PhD3*, Armand Keating, MD2, John Kuruvilla, MD, FRCPC2,4 and Rob C. Laister, PhD2

1Institute of Medical Science, University of Toronto, Toronto, ON, Canada
2Department of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON, Canada
3Human Health Therapeutics, National Research Council, Halifax, NS, Canada
4Department of Medicine, University of Toronto, Toronto, ON, Canada

Candice Jamois, PharmD1*, Koorosh Korfi, PhD2, Sylvia Herter, PhD3*, Sabine Wilson, PhD4*, Sreenath Krishnan1*, Marie-Helene Wasmer1*, Isabel Prieto5*, Heather Hinton6*, Wouter Driessen1*, Georgios Kazantzidis1*, Denis Sahin, PhD7*, Akiko Tagawa8*, Natalie Dimier, PhD9* and Katharina Lechner10*

1Pharma Research and Early Development, Roche Innovation Center Basel, Roche, Basel, Switzerland
2Pharma Research and Early Development, Innovation Center Zürich, Roche, Zürich, Switzerland
3Pharma Research and Early Development, Roche Innovation Center Zurich, Roche, Schlieren, Switzerland
4Pharma Research and Early Development, Roche Innovation Center Welwyn, Roche, Welwyn, United Kingdom
5Product Development, Innovation Center Welwyn, Roche, Welwyn, United Kingdom
6Product Development, Innovation Center Basel, Roche, Basel, Switzerland
7Product Development Oncology and Hematology, Roche Innovation Center Basel, Roche, Basel, Switzerland
8Product Development, Roche Innovation Center Basel, Roche, Basel, Switzerland
9Pharma Research and Early Development, Innovation Center Welwyn, Roche, Welwyn, United Kingdom
10Pharma Research and Early Development, Innovation Center Munich, Roche, Munich, Germany

*signifies non-member of ASH