Sebastien Jacquelin, PhD^1*, Emma Maxwell^1*, Cameron Flegg, PhD^2*, Yajun Liu^1*, Isis Taylor^1*, Ginell Ranpura^1*, Fathima Nooru-Mohamed^1*, Kamil A Sokolowski^3*, Anthony Adamson^4*, Katharine M Irvine, BSc (Hons), LLB, PhD^1* and David A Hume, BScHons, PhD^1*

¹Translational Research Institute, Mater Research Institute-University of Queensland, Brisbane, QLD, Australia
²Translational Research Institute, Imaging Facility, brisbane, QLD, Australia
³Translational Research Institute/Preclinical Imaging Facility, Brisbane, QLD, Australia
⁴University of Manchester, Manchester, United Kingdom

Kamila Bujko, PhD^1*, Mateusz Admiak, PhD^1*, Kannathasan Thetchinamoorthy, PhD^1*, Arjun Thapa, PhD^2*, Diana Wierzbicka, PhD^1*, Magdalena Molenda, MSc^1*, Mariusz Z Ratajczak, MD, PhD, DSci^1,3 and Magdalena Kucia, PhD¹

¹Laboratory of Regenerative Medicine, Medical University of Warsaw, Warsaw, Poland
²Stem Cell Institute at James Graham Brown Cancer Center, University of Louisville, Louisville, KY
³Stem Cell Institute at JGB CC, University of Louisville, Louisville, KY

Jue Li^1,2,3*, Michihiro Hashimoto, PhD^4,5,6*, Mingzhe Pan^5,6*, Hui Zeng, MD, PhD⁷, Paul R. Andreassen, PhD^8,9* and Gang Huang, PhD^5,6

¹Department of Cell Systems and Anatomy, UT Health San Antonio, Joe R. and Teresa Lozano Long School of Medicine, San Antonio, San Antonio, TX
²Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinanti, OH
³Department of Hematology, Xiangya Hospital, Central South University, Changsha, China
⁴Mays Cancer Center, UT Health San Antonio, San Antonio, TX
⁵Department of Pathology and Laboratory Medicine, UT Health San Antonio, San Antonio, TX
⁶Department of Cell Systems and Anatomy, UT Health San Antonio, San Antonio, TX
⁷Department of Hematology, Guangdong Provincial People's Hospital, South Medical University, Guangzhou, China
⁸Cincinnati Children's Hosp. Med. Ctr., Cincinnati, OH
⁹Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati

Anna Rydström, PhD^1*, Julia Sjöberg^1*, Valgardur Sigurdsson, PhD^1,2*, Shamit Soneji, PhD^3*, Stefan Lang, PhD^3*, Els Mansell, PhD^1,2 and Jonas Larsson, PhD, MD¹

¹Molecular Medicine and Gene Therapy, Lund Stem Cell Center, Lund University, Lund, Sweden
²Erasmus Medical Center, Rotterdam, Netherlands
³Molecular Hematology, Lund Stem Cell Center, Lund University, Lund, Sweden

Yuya Tanaka, MD^1*, Hiroki Kato^2*, Sayaka Sano^2*, Daigo Michimata^2*, Kazuki Sakurai^2*, Kazuki Hashimoto^2*, Naoya Morota^2*, Koichi Onodera, MD^2*, Shunsuke Hatta^2*, Noriko Fukuhara, MD, PhD³, Yasushi Onishi^2*, Tohru Fujiwara⁴ and Hideo Harigae, MD, PhD²

¹Department of Hematology, Tohoku University Graduate School of Medicine, Sendai, MIY, Japan
²Department of Hematology, Tohoku University Graduate School of Medicine, Sendai, Japan
³Department of Hematology, Tohoku University School of Medicine, Sendai, Japan
⁴Department of Laboratory Medicine, Iwate Medical University School of Medicine, Shiwa-gun, Iwate, Japan

Stefania Mazzi, PhD^1*, Tetsuichi Yoshizato, MD, PhD², Joana Carrelha, PhD^3,4*, Kari Högstrand, PhD^5*, Axel Winroth, MD^5*, Masafumi Seki, MD, PhD^5*, Bishan Wu^4*, Ellen Markljung, PhD^6*, Amy Hillen^6*, Edwin Chari^5*, Petter Woll, PhD^5* and Sten Eirik Waelgaard Jacobsen, MD, PhD^5,6,7,8*

¹Center for Hematology and Regenerative Medicine (HERM), Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden
²Center for Hematology and Regenerative Medicine (HERM) - Department of Medicine Huddinge, Karolinska Institutet, Solna, Sweden
³Department of Immunology and Inflammation, Imperial College London, London, United Kingdom
⁴University of Oxford, Oxford, United Kingdom
⁵Center for Hematology and Regenerative Medicine (HERM) - Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden
⁶Department of Cell and Molecular Biology, Karolinska Institutet, Stockholm, Sweden
⁷MRC Molecular Haematology Unit - MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
⁸Department of Hematology, Karolinska University Hospital, Stockholm, Sweden

Alexis Caulier, MD, PhD^1,2*, Jorge Diego Martin Rufino, MD, PhD^1,2, Seayoung Lee, BS^2*, Nicole Castano^1,2*, Emily King, MSc^1,2*, Samantha Joubran, MSc^1,2*, Marcus Joseph Jones^3*, Seth Raphael Goldman^3*, Uma Arora, PhD^1,2*, Lara Wahlster, MD, PhD^2,4,5, Eric Lander, PhD^2,6,7* and Vijay G. Sankaran, MD, PhD^1,2,4

¹Division of Hematology/Oncology, Boston Children’s Hospital, Harvard Medical School, Boston, MA
²The Broad Institute of MIT and Harvard, Cambridge, MA
³Nascent Transcriptomics Core, Harvard Medical School, Boston, MA
⁴Division of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
⁵Boston Children’s Hospital, Boston, MA
⁶Department of Biology, Massachusetts Institute of Technology, Cambridge, MA
⁷Department of Systems Biology, Harvard Medical School, Boston, MA

Mousumi Chakraborty, PhD^1*, Luana Chiquetto Paracatu, PhD², Zev Greenberg, PhD³, Qian Dong, MS^1*, Ashley Jones, M.S^4* and Laura G. Schuettpelz, MD, PhD¹

¹Dept. of Pediatrics, Washington University School of Medicine, St. Louis, MO
²Dept. of Pediatrics, Washington University In St Louis, St Louis, MO
³Dept. of Pediatrics, Washington University School of Medicine, Saint Louis, MO
⁴Washington University in St. Louis, Saint Louis, MO

Luana Chiquetto Paracatu, PhD¹, Qian Dong, MS^2*, Mia G Warmka, BS^2*, Liana Valin^3*, Patrick Hunt, B.S^4*, Ashley Jones, M.S^5*, Meg Schuetz^6*, Mousumi Chakraborty, PhD^7*, Zev Greenberg, PhD³, Christine RC Zhang, PhD⁸, Grant A Challen, PhD⁸, Cliff Luke^9*, Robert Signer, PhD¹⁰, Wandy Beatty, PhD^11*, David Kast, PhD^6*, Stephen Sykes, PhD¹² and Laura G. Schuettpelz, MD, PhD²

¹Dept. of Pediatrics, Washington University In St Louis, St Louis, MO
²Dept. of Pediatrics, Washington University School of Medicine, St. Louis, MO
³Dept. of Pediatrics, Washington University School of Medicine, Saint Louis, MO
⁴Dept of Pediatrics, Washington University in St. Louis, Saint Louis, MO
⁵Washington University in St. Louis, Saint Louis, MO
⁶Dept of Cell Biology & Physiology, Washington University in St. Louis, Saint Louis, MO
⁷Dept. of Pediatrics, Washington University In Saint Louis, Saint Louis, MO
⁸Division of Oncology, Washington University School of Medicine, St. Louis, MO
⁹Dept of Pediatrics, Washington University School of Medicine, St Louis, MO
¹⁰University of California San Diego, La Jolla, CA
¹¹Washington University School of Medicine, Saint Louis, MO
¹²Department of Pediatrics, Washington University School of Medicine, St Louis, MO

Xinjian Mao, PhD¹, Ning Zhang, Ph.D.^1*, Xi He, MD,. Ph.D.^1*, Ruochen Dong, Ph.D.¹, Zhe Yang, PhD¹, Michael Epp^1*, Linda Zhang^2*, Allison Scott^1*, Kate Hall^1*, Anoja Perera^1*, Jeff Haug^1*, Hua Li, Ph.D.^1*, Cheng Luo, Ph.D.^3,4*, Chuan He, Ph.D.^2,5* and Linheng Li, Ph.D.^1,6

¹Stowers Institute for Medical Research, Kansas City, MO
²Department of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL
³Zhongshan Institute for Drug Discovery, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Zhongshan, China
⁴State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China
⁵Howard Hughes Medical Institute, The University of Chicago, Chicago, IL
⁶Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS

Anne L. Robertson^1*, Lu Yue, PhD^1*, Avik Choudhuri, PhD^2*, Caroline Kubaczka, PhD^3*, Samuel J. Wattrus, PhD^1,4*, Joseph Mandelbaum, PhD^5*, Serine Avagyan, MD, PhD⁶, Song Yang, PhD^7*, Rebecca J. Freeman^1*, Victoria Chan^1*, Megan C. Blair^1*, George Q. Daley, MD, PhD⁸ and Leonard I. Zon, MD⁷

¹Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute; Howard Hughes Medical Institute; Harvard Medical School; Harvard Stem Cell Institute; Harvard University, Boston, MA
²Fulcrum Therapeutics, Cambridge, MA
³Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute; Harvard Medical School; Harvard University, Boston, MA
⁴Department of Molecular Biology, Massachusetts General Hospital, Boston
⁵Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital and Dana Farber Cancer Institute; Howard Hughes Medical Institute; Harvard Medical School; Harvard Stem Cell Institute; Harvard University, Boston
⁶University of California San Francisco, San Francisco, CA
⁷Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital; Howard Hughes Medical Institute; Harvard Medical School; Harvard Stem Cell Institute; Harvard University, Boston, MA
⁸Stem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA

Justin C. Wheat, MD, PhD¹ and Ulrich Steidl^2,3,4

¹Department of Medicine, Memorial Sloan Kettering Cancer Center, Boston, MA
²Blood Cancer Institute, Department of Oncology, Albert Einstein College of Medicine, Bronx, NY
³Department of Oncology, Montefiore Medical Center, Bronx, NY
⁴Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY