Ziyi Hu^1,2*, Yuxi Xu, MS^2,3*, Yuxuan He^1,2*, Qing Xu^1,2*, Ya Zhou^1,2*, Qi Wang^1,2*, Xiaodong Xie^1,2*, Rui Wang^1,2*, Xiaoqi Wang, MD^1*, Shijie Yang, PhD^1*, Qingxiao Song, MD, PhD^1,2 and Xi Zhang, PhD^2,4

¹Medical Center of Hematology, Xinqiao Hospital of Army Medical University, Chongqing, China
²Jinfeng Laboratory, Chongqing, China
³Medical Center of Hematology, Xinqiao Hospital of Army Medical University, Chongqing, AL, China
⁴Medical Center of Hematology, Xinqiao Hospital of Army Medical University, State Key Laboratory of Trauma and Chemical Poisoning, Chongqing Key Laboratory of Hematology and Microenvironment, Chongqing, China

Melissa Zwick^1,2*, Bastian Zinkel^1,2*, Corinna Spohr^3*, Tamina Rückert^1*, Sebastian Halbach^3,4*, Khalid Shoumariyeh, MD^1,4*, Lukas M. Braun^1,2*, Annika Nelde^5,6*, Melanie Maerklin^6,7*, Samuel J. Holzmayer^6,7*, Sandra Duquesne^1*, Alexandra Emilia Schlaak^8*, Patricia Otto-Mora^8*, Bertram Bengsch^8,9,10,11*, Marcel Schiff^1*, Sandra Kissel^1*, Marie Follo^1*, Heidi Altmann^12*, Désirée Kunadt^12*, Anna Lena Illert^1,4,13,14*, Juliane S. Walz, MD^5,6,7,15*, Gerd Walz^9,16,17*, Justus Duyster, MD^1,18*, Johannes Schetelig, MD, MSc^11,12, Tilman Brummer, PhD^3,4,9,19*, Robert Zeiser, MD^1,4,9,17 and Natalie Koehler^1,17*

¹Department of Medicine I, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
²Faculty of Biology, University of Freiburg, Freiburg, Germany
³Institute of Molecular Medicine and Cell Research (IMMZ), Zentrum für Biochemie und Molekulare Zellforschung (ZBMZ), Faculty of Medicine, University of Freiburg, Freiburg, Germany
⁴German Cancer Consortium (DKTK), Partner Site Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany
⁵Department of Peptide-based Immunotherapy, Institute of Immunology, University and University Hospital Tübingen, Tübingen, Germany
⁶Cluster of Excellence iFIT (EXC2180) "Image-Guided and Functionally Instructed Tumor Therapies", University of Tübingen, Tübingen, Germany
⁷Clinical Collaboration Unit Translational Immunology, Department of Internal Medicine, University Hospital Tübingen, Tübingen, Germany
⁸Department of Internal Medicine II (Gastroenterology, Hepatology, Endocrinology and Infectious Diseases), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
⁹BIOSS Center for Biological Signalling Studies, University of Freiburg, Freiburg, Germany
¹⁰German Cancer Consortium (DKTK), Heidelberg, Germany
¹¹Clinical Trials Unit, DKMS gGmbH, Dresden, Germany
¹²Department of Internal Medicine I, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany
¹³Department of Medicine III, Klinikum Rechts der Isar, Faculty of Medicine, Technical University of Munich, Munich, Germany
¹⁴TranslaTUM, Center for Translational Cancer Research, Technical University of Munich, Munich, Germany
¹⁵German Cancer Consortium (DKTK), Partner Site Tübingen and German Cancer Research Center (DKFZ), Tübingen, Germany
¹⁶Renal Division, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
¹⁷CIBSS – Centre for Integrative Biological Signalling Studies, University of Freiburg, Freiburg, Germany
¹⁸German Cancer Consortium (DKTK), Partner site Freiburg; and German Cancer Research Center (DKFZ), Heidelberg, Germany
¹⁹Comprehensive Cancer Center Freiburg (CCCF), Faculty of Medicine and Medical Center, University of Freiburg, Freiburg, Germany

Ji Eun Lim, PhD^1*, Srideshikan Sargur Madabushi, PhD¹, Mengistu Lemecha Shukare, PhD^2*, Hemendra Ghimire, PhD^1*, Jenny Paredes, PhD³, Sally Mokhtari, PhD⁴, James F. Sanchez, PhD^4*, Karamjeet S Sandhu, MD³, Amandeep Salhotra, MD³, Ryotaro Nakamura, MD³, Jeffrey Wong, MD^1*, Anthony S. Stein, MD³, Dorothy Schaue^5*, Marcel R.M. van den Brink, MD, PhD³, MHD Monzr M. Al Malki, MD³, Guy Storme, MD, PhD^6* and Susanta Hui, PhD^1*

¹Radiation Oncology, City of Hope National Medical Center, Duarte, CA
²Department of Molecular and Cellular Biology, City of Hope National Medical Center, Duarte, CA
³Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA
⁴Clinical and Translational Project Development, City of Hope National Medical Center, Duarte, CA
⁵Department of Radiation Oncology, University of California, Los Angeles (UCLA), Los Angeles, CA
⁶Department of Radiotherapy Universitair Ziekenhuis (UZ) Brussels, Brussels, Belgium

Shanid Mohiyuddin, PhD^1*, Vasantharaja Raguraman, PhD^1*, Nashwan Jabbour, MD^2*, Melissa Kesler, MD^2*, Jayakrishna Ambati^3*, Senthilnathan Palaniyandi, PhD^1* and Gerhard C Hildebrandt, MD¹

¹Department of Medicine, Ellis Fischel Cancer Center, University of Missouri, Columbia, MO
²University of Kentucky, Lexington, KY
³University of Virginia School of Medicine, Charlottesville, VA

Jose Antonio Bejarano Garcia^*, Melanie Nufer^*, Maria Jose Palacios Barea^*, Beatriz Guijarro-Albaladejo^*, Inmaculada Carrasco Brocal^*, Belén Sierro^*, Estefania Garcia-Guerrero, PhD^*, Maribel Lara Chica^*, Teresa Caballero, PhD, MD^*, Alfonso Rodríguez-Gil, PhD^* and Jose Antonio Pérez-Simón, MD, PhD

Instituto de Biomedicina de Sevilla (Consejo Superior de Investigaciones Científicas (CSIC), Universidad de Sevilla (US), Hospital Universitario Virgen del Rocío (HUVR))., Sevilla, Spain

Qianqian Huang, PhD^1*, Xinya Jiang^2*, Bixia Wang^3*, Zhigui Wu^1*, Fangqing Zhang^1*, Huidong Guo^4* and Xiao Jun Huang, MD⁵

¹Peking University People's Hospital & Peking University Institute of Hematology, Beijing, China
²Xiangya Hospital, Central South University, Changsha, China
³Peking University People’s Hospital, Beijing, China
⁴*Correspondence should be addressed to Xiao-Jun Huang or Huidong Guo, Peking University People's Hospital & Peking University Institute of Hematology, Beijing, China
⁵Peking University People’s Hospital, Peking University Institute of Hematology, Beijing, China

Juan Vargas^1,2*, Isabell Lang^3*, Svetlana Stepanzow^3*, Olena Zaitseva^3*, Estibaliz Arellano-Viera^4*, Carolin Graf^4*, Haroon Shaikh, PhD^2*, Muhammad Daud^5*, Sophie Barkey^5*, Harald Wajant^6* and Andreas Beilhack^7*

¹University Clinic Würzburg, Würzburg, Germany
²Department of Medicine II, University Hospital Würzburg, Würzburg, Germany
³Division of Molecular Internal Medicine, Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany
⁴Würzburg University Clinics, Würzburg, Germany
⁵Interdisciplinary Center for Clinical Research (IZKF) Experimental Stem Cell Transplantation Laboratory, Würzburg University Hospital, Würzburg, Germany
⁶University Hospital Würzburg, Würzburg, DEU
⁷Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany

Wentao Han¹, Hassan Bjeije^2*, Hamza Celik, PhD^3*, Michael P. Rettig, PhD², Yanan Li, PhD^4*, Andrew L Young, MD, PhD⁵, Christine RC Zhang, PhD², Infencia Xavier Raj, BS, MS⁶, Saranajith Dunuwille, PhD^2* and Grant A Challen, PhD²

¹Division of Oncology, Washington University School of Medicine, Saint Louis, MO
²Division of Oncology, Washington University School of Medicine, St. Louis, MO
³Incyte Research Institute, Wilmington, DE
⁴Department of Pediatrics, Division of Hematology and Oncology, Washington University School of Medicine, St. Louis, MO
⁵Division of Hematology, Washington University School of Medicine in St. Louis, St. Louis, MO
⁶Division of Oncology, Washington University In St. Louis, Saint Louis, MO

Verena Holzmüller^1,2,3*, Ulrich Thienel, MD, PhD^4*, Jana Gawron^1,3*, Kenji Cunnion, MD^5*, Neel Krishna, PhD^5*, Lindsey Glenn^5* and Robert Zeiser, MD^2,6

¹Department of Medicine I, University Medical Center Freiburg, Freiburg, Germany
²Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany
³Faculty of Biology, University of Freiburg, Freiburg, Germany
⁴UT Partners, New York, NY
⁵ReAlta Life Sciences, Norfolk, VA
⁶University of Freiburg, Faculty of Medicine, Albert Ludwigs University (ALU), Freiburg, Germany, Freiburg, Germany, Freiburg, Germany

Xiaolin Yuan, MD^1,2,3*, Lingbo Yi^4*, Yibo Wu, MD^1,3,5*, Yishan Ye, MD^1*, Luxin Yang, MD^6*, Panpan Zhu^1*, Zhiyang Yuan, PhD^4*, He Huang, MD^1,3,7*, Shanshan Pei, PhD^1,3,5* and Yi Luo^5,8,9

¹Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, hangzhou, China
²Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
³Zhejiang Province Engineering Research Center for Stem Cell and Immunity Therapy, hangzhou, China
⁴Shanghai Tissuebank Biotechnology Co., Ltd, Shanghai, China
⁵Institute of Hematology, Zhejiang University, hangzhou, China
⁶Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
⁷Institute of Hematology, Zhejiang University, Hangzhou, China
⁸Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Bone Marrow Transplantation Center of The First Affiliated Hospital & Liangzhu Laboratory, Zhejiang University School of Medicine, hangzhou, China
⁹Zhejiang Province Engineering Research Center for Stem Cell and Immunity Therapy, Hangzhou, China

Wei-Hsin Liu, MD¹, Aloukick Singh, PhD^2*, Sandeep Yadav, PhD^2*, Esther Bachar Lustig, PhD^1* and Yair Reisner, PhD^1,3,4

¹Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
²The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Immunology & Regenerative Biology, Weizmann institute of science, Rehovot, Israel
⁴CPRIT Scholar in Cancer Research, Houston, TX

Haroon Shaikh, PhD^1*, Ivana Jorgacevic, PhD^2*, Hla Ali, MSc^2*, Maja Bundalo, PhD^2*, Sarah Schäfer, PhD^2*, Michael AG Kern^1*, Maike Büttner- Herold, MD^3*, Clément Cochain, PhD^2*, Antoine-Emmanuel Saliba, PhD^4*, Giuseppe Rizzo, PhD^2*, Juan Vargas^1*, Louis Boon, PhD^5*, Wolfgang Herr, MD⁶, Hermann Einsele, MD^1*, Friederike Berberich-Siebelt, MD^7*, Andreas Rosenwald, MD^8*, Andreas Beilhack^9* and Alma Zernecke, MD^2*

¹Department of Medicine II, University Hospital Würzburg, Würzburg, Germany
²Institute of Experimental Biomedicine, University Hospital Würzburg, Würzburg, Germany
³Department of Nephropathology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⁴Helmholtz Institute for RNA-based Infection Research (HIRI), Würzburg, Germany
⁵JJP Biologics, Warsaw, Poland
⁶Internal Medicine III - Hematology and Oncology, University Hospital Regensburg, Regensburg, Germany
⁷Institute of Pathology, Julius-Maximilians-Universität Würzburg, Würzburg, Germany
⁸Comprehensive Cancer Center Mainfranken, University Hospital Würzburg, Würzburg, Germany
⁹Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany

Ying WANG^1*, Alicia Huaze Li^2*, Ruqayyah sanders-Braggs^3*, Yan Zhou, MS^4*, Mimi Chen, PhD^5*, Tien Bui^3*, Hongfa Zhu^6*, Nasheed Hossain, MD^7*, Jonathan Soboloff^8*, John Elrod^9*, Elizabeth O. Hexner, MD, MSTR¹⁰ and Yi Zhang, MD, PhD⁵

¹Center for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ
²Fels Institute for Cancer Research and Molecular Biology, Temple University, Philadelphia
³Center for Discovery and Innovation, Hackensack University Medical Center, Nutley
⁴Fox Chase Cancer Center, Temple University, Philadelphia
⁵Center for Discovery and Innovation, Hackensack University Medical Center, Nutley, NJ
⁶Hackensack Meridian Health, Hackensack
⁷Division of Hematology/Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA
⁸Temple University School of Medicine, Philadelphia, PA
⁹Center for Translational Medicine, Temple University, Philadelphia
¹⁰Abramson Cancer Center, Department of Medicine, Division of Hematology-Oncology, University of Pennsylvania, Philadelphia, PA

Xie-Na Cao, MD, PhD^1*, Wen-Kai Zhang, MD^1*, Wei Shi, PhD^2*, Ling-Hui Xia, MD, PhD^1*, Li Li, MD^3*, Chun-Yan Sun, MD^1* and Yu Hu^4*

¹Institute of Haematology, Huazhong University of Science and Technology, Union Hospital, Tongji Medical School, Wuhan, China
²Institute of Hematology, Union Hospital, Tongji Medical School, Huazhong University of Science and Technology, Wuhan, China
³Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD
⁴Institute of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China