Anasuya Hazra^*, Anita Boyapati^*, Ching-Ha Lai^*, Kate Knorr^*, Dhruti Chokshi^*, Glenn S. Kroog^*, Karen Rodriguez Lorenc, A. Thomas DiCioccio^* and John D. Davis^*

Regeneron Pharmaceuticals, Inc., Tarrytown, NY

Lorenzo Cani, MD^*, Sara A. Scott, PharmD^*, Nisha S. Joseph, MD, Craig C. Hofmeister, MD, Vikas A. Gupta, MD PhD, Madhav V. Dhodapkar, MD PhD, Sagar Lonial, MD^*, Ajay K. Nooka, MD, MPH and Jonathan L. Kaufman, MD

Winship Cancer Institute of Emory University, Atlanta, GA

Robbe Heestermans, MD^1,2,3*, Catharina Olsen, PhD^4,5*, Jana Succari, MSc^2*, Shervine Ameli, M.D.^2*, Toon Janssen, PhD^4*, Ann De Becker, M.D., PhD^1,2*, Isabelle Vande Broek, M.D., PhD^6*, Marleen Bakkus, PhD^1,7*, Rik Schots, M.D., PhD^1,2, Elke De Bruyne, PhD^1* and Ivan Van Riet, PhD^1,2*

¹Translational Oncology Research Center (Team Hematology and Immunology), Vrije Universiteit Brussel (VUB), Brussels, Belgium
²Department of Hematology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium
³Department of Clinical Biology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Jette, Belgium
⁴Brussels Interuniversity Genomics High Throughput Core (BRIGHTcore), Vrije Universiteit Brussel (VUB), Université Libre de Bruxelles (ULB), Brussels, Belgium
⁵Clinical Sciences, Research Group Reproduction and Genetics, Centre for Medical Genetics, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium
⁶Department of Oncology and Hematology, VITAZ Hospital, Sint-Niklaas, Belgium
⁷Department of Clinical Biology, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Brussels, Belgium

Rikako Tabata, M.D.^1*, Mitsuaki Oura, M.D.^2*, Daisuke Ikeda, M.D.^3*, Shuichi Aikawa^4*, Chiho Misono^4*, Fuminari Fujii, M.D.^1*, Hajime Sakuma, M.D.^2*, Masanori Toho, MD^2*, Atsushi Uehara^5*, Kentaro Narita, M.D.^1*, Masami Takeuchi, M.D.^2*, Tomohisa Watari^4*, Yoshihito Otsuka, Ph.D.^4* and Kosei Matsue, M.D., Ph.D.²

¹Division of Hematology/Oncology, Kameda Medical Center, Kamogawa, Japan
²Division of Hematology/Oncology, Kameda Medical Center, Kamogawa, Chiba, Japan
³Department of Hematology and Oncology, Okayama University Hospital, Okayama, Japan
⁴Department of Laboratory Medicine, Kameda Medical Center, Chiba, Japan
⁵Division of Hematology/Oncology, Kameda Medical Center, Kamogawa-Shi, Japan

Kristin Ezell, MD¹, Katharine Hooper, FNP-BC^2*, Kaylyn Kirk, DO^3*, Ritika Vankina, MBBS^2* and Swarup Kumar, MBBS²

¹University of Connecticut, West Hartford, CT
²Carole and Ray Neag Comprehensive Cancer Center, University of Connecticut, Farmington, CT
³University of Connecticut, Farmington, CT

Adrian A Almodovar Diaz¹, Samhar Alouch^2*, Angela Dispenzieri, MD³, Udit Yadav, MBBS^4*, Francis Buadi, MD³, David Dingli, MD, PhD³, Eli Muchtar, MD³, Nelson Leung, MD⁵, Taxiarchis Kourelis, MD³, Rahma M Warsame, MD³, Ronald S Go, M.D.⁶, Moritz Binder, MD³, Joselle Cook, MBBS³, Miriam Hobbs, APRN, CNP, DNP^3*, Yi Lisa Hwa, APRN, DNP, CNP³, Amie Fonder, PA-C, MS^7*, Michelle G. Rogers, CNP^3*, Suzanne R Hayman, MD³, Yi Lin, MD, PhD³, Mustaqeem A. Siddiqui, MD, MBA³, Robert A. Kyle, MD³, Morie A. Gertz, MD³, Vincent Rajkumar, MD^3* and Wilson I. Gonsalves, MD⁸

¹University of Puerto Rico School of Medical Sciences, San Juan, PR
²Alfaisal University, Riyadh, Saudi Arabia
³Division of Hematology, Mayo Clinic, Rochester, MN
⁴Division of Hematology/Oncology, Mayo Clinic Arizona, Phoenix, AZ
⁵Division of Nephrology, Hematology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
⁶Division of Medical Oncology, Mayo Clinic, Onalaska, WI
⁷Hematology, Mayo Clinic, Rochester, MN
⁸Division of Hematology, Mayo School of Graduate Medical Education, Rochester, MN

Maher Albitar, MD¹, Hong Zhang, MD^1*, Sally Agersborg, MD, PhD^1*, Ahmad Charifa, MD^1*, Pooja Phull, MD^2*, Noa Biran, MD², David H. Vesole, MD, PhD³, Harsh Parmar, MD², Andrew L Pecora, MD⁴, Andrew Ip, MD, MSc⁵, Andre Goy, MD, MS⁶ and David S. Siegel, MD, PhD⁴

¹Genomic Testing Cooperative, Lake Forest, CA
²Division of Multiple Myeloma, John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ
³John Theurer Cancer Center, Hackensack, NJ
⁴Hackensack University Medical Center, Hackensack, NJ
⁵Lymphoma Division, John Theurer Cancer Center, Hackensack Meridian Health, Hackensack, NJ
⁶John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ

Priyanka Venkatesh, MBBS^1,2, Razan Mansour, MD^1,2*, Hamid Ehsan, MD^1,3*, Nausheen Ahmed, MD^1,4, Muhammad Umair Mushtaq, MD^1,5, Al-Ola Abdallah, MD^1,6, Shebli Atrash, MD^1,3 and Barry Paul, MD, MS^1,3

¹US Myeloma Innovations Research Collaborative (USMIRC), Kansas City, KS
²Internal Medicine, The University of Kansas Medical Center, Kansas City, KS
³Levine Cancer Institute, Atrium Health Wake Forest University School of Medicine, Charlotte, NC
⁴Division of Hematologic Malignancies & Cellular Therapeutics, University of Kansas Medical Center, Westwood, KS
⁵Division of Hematologic Malignancies & Cellular Therapeutics, University of Kansas Medical Center, Overland Park, KS
⁶Division of Hematologic Malignancies & Cellular Therapeutics, University of Kansas Medical Center, Kansas City, KS

Georgia Riga^1,2*, Vincent Luong^1,3*, Katarina Uttervall^1,3*, Gösta Gahrton, MD, PhD¹, Hareth Nahi, MD, PhD^1,4,5*, Johan Lund, MD, PhD^1,3*, Evren Alici, MD¹ and Muhammad Kashif, PhD^6*

¹Department of Medicine, Karolinska Institutet, Stockholm, Sweden
²Department of Information Technology, Uppsala University, Uppsala, Sweden
³Hematology Medical Unit, Karolinska University Hospital, Stockholm, Sweden
⁴Pfizer Inc., Stockholm, Sweden
⁵Department of Medicine, Södersjukhuset, Stockholm, Sweden
⁶Department of Medicine, Karolinska Institutet, Huddinge, Sweden

Arwa Bohra, MBBS^1*, Rafla Hassan, MBBS^1*, Saurabh Zanwar, MD^1*, Dragan Jevremovic, M.D., Ph.D^2*, Horatiu Olteanu, M.D., Ph.D.², Wilson I. Gonsalves, MD³, Gregory Otteson^4*, Pedro Horna, MD², S. Vincent Rajkumar, MD^1* and Shaji Kumar, MD¹

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Division of Hematopathology, Mayo Clinic, Rochester, MN
³Division of Hematology, Mayo School of Graduate Medical Education, Rochester, MN
⁴Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN

Vincent Luong^1,2*, Muhammad Kashif, PhD^1*, Katarina Uttervall, MD, PhD^1,2*, Anna Bohlin^1*, Nursen Cetrez, MD^1*, Gabriel Afram^1,2,3*, Hareth Nahi, MD, PhD^1,4,5*, Johan Lund, MD, PhD^1,2* and Evren Alici, MD^1,2

¹Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Stockholm, Sweden
²Department of Hematology, Karolinska University Hospital, Stockholm, Sweden
³Pfizer Inc, Solna, Sweden
⁴Pfizer Inc., Stockholm, Sweden
⁵Department of Medicine, Södersjukhuset, Stockholm, Sweden

Luis Gerardo Rodríguez-Lobato^1*, Anna De Daniel, MD^2*, Arturo Pereira, MD, PhD^3*, Carlos Fernández de Larrea, MD⁴, Natalia Tovar^4*, M Teresa Cibeira López, MD, PhD^5*, David F. Moreno, MD, PhD^4*, José Miguel Mateos Pérez, MD^6*, Joan Bladé, MD, PhD^7* and Laura Rosinol Dachs, MD PhD^8*

¹Department of Hematology, Hospital Clínic de Barcelona, Barcelona, Spain., Barcelona, Spain
²Hospital Clínic of Barcelona, Barcelona, ESP
³Hospital Clínic de Barcelona, Barcelona, BARCELONA, Spain
⁴Hospital Clínic de Barcelona, Barcelona, Spain
⁵Hospital Clinic of Barcelona, University of Barcelona, IDIBAPS, Barcelona, Spain
⁶Department of Hematology, Hospital Clinic Barcelona, Barcelona, Spain
⁷Amyloidosis and Multiple Myeloma Unit, Department of Hematology, IDIBAPS, Hospital Clinic, Spain, Barcelona, Spain
⁸Hematopoietic Cell Transplant Unit, Hospital Clínic de Barcelona, ICAMS, Barcelona, Spain

Martin K. Kortüm^1*, Sebastian Theurich, MD^2*, James Farrell^3*, Joseph C. Cappelleri, PhD^4*, Olivia Ashman^5*, Shanti Neff-Baro^6*, Aline Gauthier^7*, Khalil Jewiti-Rigondza^7* and Christof Scheid^8*

¹Würzburg University Hospital, Wuerzburg, Germany
²Department of Medicine III, LMU University Hospital, LMU Munich, Munich, Germany
³Pfizer Ltd, Dublin, Ireland
⁴Pfizer Inc, Groton, CT
⁵Pfizer Ltd, London, United Kingdom
⁶Amaris Ltd, Paris, France
⁷Amaris Ltd, Barcelona, Spain
⁸Cologne University Hospital, Cologne, Germany

Sonia More'^1,2*, Valentina Maria Manieri^1,3*, Laura Corvatta^4*, Erika Morsia^1,2*, Shahram Kordasti, MD, PhD^1,3,5, Attilio Olivieri^1,2*, Antonella Poloni, PhD^1,2* and Massimo Offidani, MD ^6*

¹Hematology Unit, Azienda Ospedaliero Universitaria delle Marche, Ancona, Italy
²Hematology Unit, Department of Clinical and Molecular Sciences, Università Politecnica delle Marche, Ancona, Ancona, Italy
³Department of Clinical and Molecular Sciences, DISCLIMO, Università Politecnica delle Marche, Ancona, Ancona, Italy
⁴UOC Medicina, Ospedale Profili, Fabriano, ITA
⁵Department of Clinical Haematology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom
⁶Clinica di Ematologia Ospedali Riuniti Ancona, Ancona, Italy

Raheel Iftikhar, MBBS, FCPS¹, Natasha Ali, MBBS^2*, Danyal Ahmad Ghani, FCPS^3*, Maryam Khan^1*, Nida Anwar^4*, Syed Waqas Imam Bokhari, MBBS, MRCP, FRCPath^5*, Uzma Zaidi^6*, Usman Ahmed^5*, Shahzad Sarwar^7*, Saima Humayun^1*, Ayesha Iftikhar^3*, Bushra Ahsan^5*, Farrukh Ali Khan^8*, Aisha Jamal^4*, Fawad Qureshi^8*, Munira Moosajee^2*, Umar Zahur^9*, Munira Borhany^10*, Muhammad Ayaz Mir^3* and Salman Naseem Adil^2*

¹Armed Forces Bone Marrow Transplant Centre, Rawalpindi, Pakistan
²Aga Khan University, Karachi, Pakistan
³Shifa International Hospital, Islamabad, Pakistan
⁴National Institute of Blood Disease & Bone Marrow Transplantation, Karachi, Pakistan
⁵Shaukat Khanum Memorial Cancer Hospital & Research Center, Lahore, Pakistan
⁶King Hamad University Hospital, Al Sayh, Bahrain
⁷Gambat Institute of Medical Sciences, Gambat, Pakistan
⁸Dow University of Health Sciences, Karachi, Pakistan
⁹Quaid-e-Azam International Hospital, Islamabad, Pakistan
¹⁰Ziauddin Hospital, Karachi, Pakistan

Yuyue Ren, MD^1*, Ming Liu, MD^2*, Jiancheng Fang, MD^2*, Lianjie Wang^1*, Liqian Yu^1*, Yanming Xue^1*, Weiwei Zhao^1*, Juan Liu^1*, Yinglan Jin^1*, Yaoyao Tian^1*, Liyan Chen^1*, Panxiang Cao^2*, Fang Wang, MD^2*, Hongxing Liu, MD^2,3,4 and Wei Wang, MD^1*

¹Department of Hematology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China
²Pathology & Laboratory Medicine Division, Hebei Yanda Lu Daopei Hospital, Langfang, Hebei, China
³Precision Medicine Center, Beijing Lu Daopei Institute of Hematology, Beijing, China
⁴Department of Laboratory Medicine, Lu Daopei Hematology & Oncology Center, Hebei Yanda Hospital, Beijing, Beijing, China

Claudio Cerchione, MD¹, Davide Bezzi^2*, Davide Nappi, M.D.^3*, Matteo Marchesini, PhD^3*, Andrea Prochowski Iamurri^4*, Paola Caroli, M.D.^5*, Arrigo Cattabriga, MD^6*, Delia Cangini, M.D.^3*, Giacomo Feliciani, Ph.D.^3*, Emiliano Loi^7*, Federica Matteucci^8*, Domenico Barone^8*, Sonia Ronconi, M.D.^3*, Michela Ceccolini, M.D.^3*, Gerardo Musuraca, M.D., Ph.D.^3*, Nicola Normanno, M.D.^3*, Giovanni Martinelli, M.D.³ and Alice Rossi, M.D.^3*

¹Hematology Unit, Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST IRCCS, Meldola (FC), Italy
²Nuclear Medicine Unit, AUSL Romagna, Forli, Italy
³IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola (FC), Italy
⁴IRCCS Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" (IRST), Meldola, Italy
⁵IRCCS Istituto Romagnolo Per Lo Studio Dei Tumori dino Amadori IRST, Meldola, Meldola, Italy
⁶Department of Radiology, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy
⁷IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy
⁸Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" - IRST IRCCS, Meldola (FC), Italy

Anthony Colombo, PhD¹, Esther Lam, MPH^2*, Ben Falk^3*, Anton Luis Villamejor^4*, Amie Hwang, PhD, MPH^5*, Jose Aparicio^6*, Jia Yin Wan, M.S.^7*, Chun R. Chao, PhD, MS^8*, Mallory Bernstein^9*, Ravi Vij, MD, MBA¹⁰, Mark Fiala, PhD^11*, Pei Lin, MD, DM, MDPC¹², Robert Z. Orlowski, MD, PhD¹³, Imran Siddiqi, MD, PhD^14*, David Conti^15*, Akil Merchant, MD¹⁶ and Wendy Cozen, DO, MPH¹⁷

¹Department of Population and Public Health Sciences, University of Southern California, Keck School of Medicine, Whittier, CA
²Department of Pathology and Laboratory Medicine, University of California Irvine, Orange, CA
³Samuel Oschin Cancer Institute, Cedars-Sinai, Los Angeles, CA
⁴Division of Hematology and Cellular Therapy, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA
⁵Keck School of Medicine University of Southern California, Los Angeles, CA
⁶Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA
⁷University of California, Irvine, Irvine, CA
⁸Department of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA
⁹University of California, Irvine School of Medicine, Irvine, CA
¹⁰Division of Oncology, Washington University School of Medicine, St. Louis, MO
¹¹Division of Oncology, Washington University School of Medicine, Saint Louis, MO
¹²Department of Hematopathology, M.D. Anderson Cancer Center, Houston, TX
¹³Department of Lymphoma & Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁴University of Southern California, Norris Comprehensive Cancer Center, Los Angeles, CA
¹⁵Department of Population and Public Health Sciences, University of Southern California, Los Angeles, CA
¹⁶Samuel Oschin Cancer Center, Cedars-Sinai Medical Center, Los Angeles, CA
¹⁷Division of Hematology-Oncology, Department of Medicine, UCI, School of Medicine, Orange, CA

Heinz Ludwig, MD¹, Meletios A. Dimopoulos, MD², Meral Beksac, MD³, Frank Bridoux, MD, PhD^4*, Guldane Cengis-Seval^3*, Luca Arcaini, MD^5,6*, Foteini Theodorakakou, MD^7*, Hermine Agis, Prof MD⁸, Francesca Gay, MD, PhD⁹, Aristeidis Chaidos, MD, PhD^10*, Dario Roccatello^11*, Daniele Derudas^12*, Andrea Havasi, MD^13*, Julie Krainer, MSc^1*, Silvia Mangiacavalli, MD^14*, Elise Michelon^15*, Javier De La Rubia^16*, Nattawat Klomjit, MD^17*, Tamer Shehab^18*, Kenar Jhaveri^19*, Nelson Leung, MD²⁰ and Efstathios Kastritis, MD, PhD^7*

¹Wilhelminen Cancer Research Institute, c/o Department of Medicine I, Clinic Ottakring, Vienna, Austria
²National and Kapodistrian University of Athens, Athens, Greece
³Akademik Veri Yönetim Sistemi, Ankara Üniversitesi, Ankara, Turkey
⁴Néphrologie, CHU de Poitiers, Poitiers, France
⁵Department of Molecular Medicine, University of Pavia, Pavia, Italy
⁶Fondazione IRCCS Policlinico San Matteo and University of Pavia, Pavia, Italy
⁷Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
⁸Department Internal Medicine I, Division Hematology & Hemostaseology, Medical University of Vienna, Vienna, Austria
⁹Myeloma Unit, Division of Hematology, University of Torino, A.O.U. S., Torino, Italy
¹⁰Hugh and Josseline Langmuir Centre for Myeloma Research, Centre for Haematology, Department of Immunology and Inflammation, Imperial College London and Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom
¹¹University Center of Excellence on Nephrological, Rheumatological and Rare Diseases, San Giovanni Bosco Hub Hospital, Turin, Italy
¹²Department of Hematology, Struttura Complessa di Ematologia e Centro Trapianto Cellule Staminali Emopoieti, Cagliari, Italy
¹³Renal Section, Boston University School of Medicine, Boston, MA
¹⁴Division of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
¹⁵Dep. of Nephrology & Renal Transplantation, Université de Poitiers, CHU Poitiers, Poitiers, France
¹⁶Hospital Universitario y Politécnico La Fe, Valencia, Spain
¹⁷Division of Nephrology and Hypertension, University of Minnesota, Rochester, MN
¹⁸Cairo Kidney Center, Cairo, Egypt
¹⁹Feinstein Institute for Medical Research, Manhasset
²⁰Division of Nephrology, Hematology, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN

Zachary M Avigan, MD¹, Saoirse Bodnar^1*, Darren Pan, MD¹, Adolfo Aleman, Jr.^2*, Joshua Richter, MD³, Larysa J Sanchez, MD¹, Cesar Rodriguez, MD^1*, Adriana Rossi, MD, MSc¹, Shambavi Richard, MD², Hearn Jay Cho, MD, PhD², Sundar Jagannath, MD², Samir Parekh, MD⁴ and Santiago Thibaud, MD^1*

¹Department of Medicine, Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
²Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
³Icahn School of Medicine at Mount Sinai, New York, NY
⁴Department of Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY

Febe Smits, MD^1,2,3*, Kazem Nasserinejad, PhD^4,5*, Mark-David Levin⁶, Gert Jan Timmers, MD, PhD^7*, Esther G.M. De Waal, MD^8*, Josien C Regelink, MD^9*, Gerjo A. Velders, PhD, MD^10*, Matthijs Westerman, MD^11*, Nazik Durdu-Rayman, MD, PhD^12*, Suzanne Last-Koopmans^13*, Roel JW van Kampen, MD PhD¹⁴, Claudia A M Stege, MD, PhD^15*, Kaz Groen, MD^1,2*, Maarten R. Seefat, MD^1,2*, Monique C. Minnema¹⁶, Pieter Sonneveld, MD¹⁵, Paula F Ypma, MD, PhD^3*, Niels W.C.J. van de Donk, MD, PhD^1,2* and Sonja Zweegman, MD, PhD^1,2

¹Department of Hematology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
²Treatment and Quality of Life, Cancer Center Amsterdam, Amsterdam, Netherlands
³Department of Hematology, HagaZiekenhuis, The Hague, Netherlands
⁴Department of Hematology, Erasmus MC, University Medical Center, Rotterdam, Netherlands
⁵HOVON foundation, Rotterdam, Netherlands
⁶Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, Netherlands
⁷Department of Internal Medicine, Amstelland Hospital, Amstelveen, Netherlands
⁸Department of Internal Medicine, Medical Center Leeuwarden, Leeuwarden, Netherlands
⁹Department of Internal Medicine, Meander Medical Center, Amersfoort, Netherlands
¹⁰Department of Internal Medicine, Gelderse Valei Hospital, Zutphen, Netherlands
¹¹Department of Internal Medicine, Northwest Clinics, Alkmaar, Netherlands
¹²Department of Internal Medicine, Franciscus Hospital, Schiedam, Netherlands
¹³Department of Internal Medicine, Beatrix Hospital, Gorinchem, Netherlands
¹⁴Department of Internal Medicine, Zuyderland Medical Center, Sittard-Geleen, Netherlands
¹⁵Department of Hematology, Erasmus Medical Center, Rotterdam, Netherlands
¹⁶Department of Hematology, University Medical Center Utrecht, Utrecht, Netherlands

Thomas G. Martin, MD¹, María-Victoria Mateos, MD, PhD², Niels W.C.J. van de Donk, MD, PhD^3*, Zhen Cai^4*, Weijun Fu^5*, Alfred L Garfall^6*, Shinsuke Iida, MD, PhD⁷, Yoshiaki Kuroda^8*, Ting Niu, MD, PhD⁹, Ajay K. Nooka, MD, MPH¹⁰, Surbhi Sidana, MD¹¹, Katherine Chastain, MD¹², Margaret Doyle¹³, Kazuko Nishikawa^14*, Yang Song^15*, Hiroshi Yamazaki, MS^14*, Jianmin Zhuo^16*, Yan Zhu, PhD^17*, Juan Du, MD, PhD¹⁸ and Tadao Ishida¹⁹

¹University of California, San Francisco, San Francisco, CA
²University Hospital of Salamanca/IBSAL/CIC/CIBERONC, Salamanca, Spain
³Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
⁴International College Zhejiang, University West District of Zijingang Campus, Zhejiang, China
⁵Shanghai Changzheng Hospital, Naval Medical University, Shanghai, China
⁶Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
⁷Nagoya City University Institute of Medical and Pharmaceutical Sciences, Nagoya, Japan
⁸Hiroshima-Nishi Medical Center, National Hospital Organization, Hiroshima, Japan
⁹Department of Hematology, West China Hospital, Sichuan University, Chengdu, Sichuan, China
¹⁰Winship Cancer Institute of Emory University, Atlanta
¹¹Stanford University School of Medicine, Stanford, CA
¹²Janssen Research & Development, Raritan, NJ
¹³Janssen Global Services, Dublin, Ireland
¹⁴Research and Development Division, Janssen Pharmaceutical K.K., Tokyo, Japan
¹⁵Janssen Research & Development, Beijing, China
¹⁶Janssen (China) Research & Development, Shanghai, China
¹⁷Janssen Asia Pacific Medical Affairs, Singapore, Singapore
¹⁸Department of Hematology, Myeloma & Lymphoma Center, Shanghai Changzheng Hospital, Shanghai, China
¹⁹Japanese Red Cross Medical Center, Tokyo, Japan

Maksim V Soloviev, MD, PhD^1*, Larisa Mendeleeva, MD, PhD^1*, Olga Samoilova, MD, PhD^2*, Igor Davydkin, MD, PhD^3*, Kamil Kaplanov, MD, PhD^4*, Tatiana Kaporskaya, MD, PhD^5*, Elena Martynova, MD^6*, Michael Mikhalev, MD^7*, Marina Savinova, MD^8*, Elena Volodicheva, MD, PhD^9*, Tatiana Ianovna Pospelova, MD, PhD^10*, Natalia Skvortsova, MD, PhD^11*, Tatyana Shelekhova, MD, PhD^12*, Svetlana Belyaeva, MD^13*, Elena Kuznetsova, MD^14*, Natalya Rachkova, MD^15*, Marina Kiseleva, MD^16*, Tatiana Konstantinova, MD, PhD^17*, Maria Frolova, MD^18*, Maiia Soloveva, MD, PhD^1*, Svetlana Osyunikhina, MD^19*, Svetlana Menshakova, MD^20*, Tatiana Ksenzova, MD^21*, Ekaterina Filatova, MD^22*, Anna Alekseeva, MD^23*, Elena Voronova, MD^24*, Irina Verkhoglyad, MD^25*, Elena Patrakova, MD^26*, Yulia Chizhova, MD^27*, Zhanna Davydova, MD^28*, Yuri Dunaev, MD^29*, Tatiana Sycheva, MD^30*, Tatiana Chagorova, MD^31*, Nadezhda Stepanova, MD^32*, Marina Kozmina, MD^33*, Elena Kirillova, MD^34*, Elena Borisenkova, MD^35*, Natalia Popova, MD^36*, Natalia Esefieva, MD^37*, Irina Soklova, MD^38*, Alexandra Gvozdareva, MD^39*, Anton Shutylev, MD^40* and Elena Tarasenko, MD^41*

¹National Medical Research Center for Hematology, Moscow, Russian Federation
²Nizhny Novgorod Regional Clinical Hospital named after N A Semashko, Nizhniy Novgorod, Russian Federation
³Federal State Budgetary Educational Institution of Higher Education “Samara State Medical University” of the Ministry of Healthcare of the Russian Federation, Samara, Russian Federation
⁴Regional Clinical Hospital, Volgograd, Russian Federation
⁵Regional Clinical Hospital, Irkutsk, Russian Federation
⁶Regional Clinical Hospital, Krasnoyarsk, Russian Federation
⁷City Clinical Hospital No. 7, Krasnoyarsk, Russian Federation
⁸City Clinical Hospital N16, Kazan, Russian Federation
⁹Regional Clinical Hospital, Tula, Russian Federation
¹⁰Medical State University, Novosibirsk, RUS
¹¹Medical State University, Novosibirsk, Russian Federation
¹²Medical University, Saratov, Russian Federation
¹³Regional Clinical Hospital, Belgorod, Russian Federation
¹⁴Regional Clinical Hospital, Orenburg, Russian Federation
¹⁵Regional Clinical Hospital, Bryansk, Russian Federation
¹⁶Regional Clinical Hospital, Simferopol, Russian Federation
¹⁷Regional Clinical Hospital No 1, Ekaterinburg, Russian Federation
¹⁸Regional Clinical Hospital, Vologda, Russian Federation
¹⁹Regional Clinical Hospital, Saransk, Russian Federation
²⁰Regional Clinical Hospital, Tver, Russian Federation
²¹Regional Clinical Hospital, Tyumen, Russian Federation
²²Regional Clinical Hospital, Blagoveshchensk, Russian Federation
²³Regional Clinical Hospital, Ulan Ude, Russian Federation
²⁴Regional Clinical Hospital, Tambov, Russian Federation
²⁵Regional Clinical Hospital, Khabarovsk, Russian Federation
²⁶Oncology Center, Cherepovets, Russian Federation
²⁷Regional Clinical Hospital, Kemerovo, Russian Federation
²⁸Russian Railways Hospital, Smolensk, Russian Federation
²⁹Regional Clinical Hospital, Arkhangelsk, Russian Federation
³⁰Regional Clinical Hospital, Astrakhan, Russian Federation
³¹Regional Oncology Dispensary, Penza, Russian Federation
³²Hospital, Orsk, Russian Federation
³³City Polyclinic, Orel, Russian Federation
³⁴Regional Clinical Hospital, Omsk, Russian Federation
³⁵Regional Clinical Hospital, Kaluga, Russian Federation
³⁶District Hospital, Surgut, Russian Federation
³⁷Regional Clinical Hospital, Ulyanovsk, Russian Federation
³⁸Oncology Center, Syktyvkar, Russian Federation
³⁹Regional Clinical Hospital, Yaroslavl, Russian Federation
⁴⁰City clinic 5, Perm, Russian Federation
⁴¹City Hospital N1, Sevastopol, Russian Federation

Sarah Gooding, MD, PhD^1,2*, Kara-Louise Royle^3*, Mohammad Kazeroun^2*, Robert Cicero, MSc^3*, Laura Chiecchio, PhD^4*, Dipal Mehta, MBBS MRCP^5*, Emma J Lyon^5*, Bethan Hudson-Lund^5*, Jasmin Rahman^5*, Khrystal McBean^6*, Martin F Kaiser, MD⁷, Catherine Olivier, MA^3*, Doina Levinte^3*, Charlotte Kennaway, MD^3*, Dean Smith, BA(Hons) MBBS MRCP FRCPath MD(Res)^8,9*, Jonathan Sive, MD^10*, Ceri Bygrave, MBBCh MRCP FRCPath^11*, Guy Pratt^12*, Michael A. Chapman, PhD¹³, Graham Jackson, MD^14*, Rakesh Popat, MBBS, PhD^5,15, Christopher Parrish, MBBChir, MRCP, FRCPath, MA, PhD³, Gordon Cook, PhD, DSc^3*, Angela Hamblin, MD, PhD^2,16*, Naser Ansari-Pour, PhD^2*, David A. Cairns, PhD^3*, Anjan Thakurta, PhD², Karthik Ramasamy, MD, PhD^2,6, Eileen M Boyle, MBChB, PhD⁵, Kwee Yong, MD, PhD⁵ and Matthew W. Jenner^17*

¹MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
²Oxford Translational Myeloma Centre, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), University of Oxford, Oxford, United Kingdom
³Cancer Research UK Clinical Trials Unit, Leeds Institute of Clinical Trials Research, University of Leeds, Leeds, United Kingdom
⁴University Hospital Southampton, Wessex Regional Genetics Laboratory Service (Salisbury), Southampton, GBR
⁵UCL Cancer Institute, University College London, London, United Kingdom
⁶Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
⁷The Institute of Cancer Research, London, United Kingdom and the Royal Marsden Hospital, London, United Kingdom
⁸Clinical Haematology, Nottingham University Hospitals NHS Trust, Nottingham, United Kingdom
⁹School of Medicine, University of Nottingham, Nottingham, United Kingdom
¹⁰Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom
¹¹Department of Haematology, Cardiff & Vale University Health Board, Cardiff, United Kingdom
¹²University Hospitals Birmingham NHS FT, Birmingham, United Kingdom
¹³Department of Haematology, University of Cambridge, Cambridge, United Kingdom
¹⁴University of Newcastle, Department of Haematology, Newcastle, United Kingdom
¹⁵NIHR UCLH Clinical Research Facility, University College London Hospitals NHS Foundation Trust, London, United Kingdom
¹⁶Department of Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
¹⁷University Hospital Southampton, Southampton, United Kingdom

Rasmus Rønnemoes, MD^1,2*, Anne Rudbeck Juhl, MD^2,3,4*, Shoaib Afzal, MD, PhD, DMSci^2,4,5*, Stig Egil Bojesen, MD, DMSci^2,4,5*, Boerge Groenne Nordestgaard, MD, DMSci^2,4,5*, Michael Huy Cuong Pham, MD^6*, Klaus Fuglsang Kofoed, MD, PhD, DMSci^4,6*, Jørgen Tobias Kühl, MD, PhD^7*, Andreas Fuchs, MD, PhD^6*, Per Ejlstrup Sigvardsen, MD, PhD^6*, Thomas S. Kristensen, MD, PhD^8*, Jesper Petersen, PhD^3*, Andreas Glenthoej, MD, PhD^3,4 and Jens Helby, MD, PhD^2,3,4*

¹Danish Red Blood Cell Center, Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, AL, Denmark
²The Copenhagen General Population Study, Copenhagen University Hospital – Herlev and Gentofte, Herlev, Denmark
³Danish Red Blood Cell Center, Department of Hematology, Copenhagen University Hospital - Rigshospitalet, Copenhagen, Denmark
⁴Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
⁵Department of Clinical Biochemistry, Copenhagen University Hospital – Herlev and Gentofte, Herlev, Denmark
⁶Department of Cardiology, The Heart Centre, Rigshospitalet - Copenhagen University Hospital, Copenhagen, Denmark
⁷Department of Cardiology, Zealand University Hospital, Roskilde, Denmark
⁸Department of Radiology, Rigshospitalet - Copenhagen University Hospital, Copenhagen, Denmark

Tadeusz Kubicki^*, Kaina Millan^*, Anna Pula^*, Henry Raeder^*, Quinn Hauck^*, Manoj Bhagwat^*, Jude Barton^*, Eyitayo Awe^*, Soma Das^*, Daniela Del Gaudio^*, Sulin Wu, MD, PhD, Frank Wen, MD, PhD, Jennifer H Cooperrider, MD, Benjamin A Derman, MD, Andrzej J Jakubowiak, MD, PhD and Michael W Drazer, MD, PhD

Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL

Bei Wang^1*, Benjamin A Derman, MD², Zhou Zhang^3*, Krissana Kowitwanich^4*, John F. Cursio, PhD^5*, Daniel Appelbaum^6*, Chuan He, Ph.D.^7*, Wei Zhang^3*, Andrzej J Jakubowiak, MD, PhD² and Brian Chiu, PhD¹

¹Department of Public Health Sciences, University of Chicago, Chicago, IL
²Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL
³Northwestern University Feinberg School of Medicine, Chicago, IL
⁴Department of Chemistry, University of Chicago, Chicago, IL
⁵University of Chicago Biological Sciences Division, Chicago, IL
⁶Department of Radiology, University of Chicago, Chicago, IL
⁷Department of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL

Oren Pasvolsky, MD¹, Aimaz Afrough^2*, Lei Feng, MS^3*, Wenli Dong^3*, Tiffany Richards, PhD, NP⁴, James A Davis, PharmD^5*, Danai Dima, MD⁶, Ariel Grajales-Cruz^7*, Mariola A Vazquez-Martinez, MD⁷, Aishwarya Sannareddy, MBBS^2*, Utkarsh Goel, MBBS⁸, Rahul Banerjee, MD, FACP⁹, Mahmoud R. Gaballa, MD⁴, Alex Lieberman-Cribbin^10*, Masooma S Rana, MBBS^11*, Kelley Julian, PharmD^12*, Christopher J Ferreri, MD^13*, Leyla O. Shune, MD¹⁴, Shaun DeJarnette^14*, Evguenia Ouchveridze, MD¹⁵, Sandra Susanibar-Adaniya, MD¹⁶, Andrew J. Portuguese¹⁷, Peter A. Forsberg, MD¹⁸, Hitomi Hosoya, MD, PhD¹⁹, Lekha Mikkilineni, MD, MA¹⁹, Gurbakhash Kaur, MD, MA²⁰, Adriana Rossi, MD, MSc¹⁰, Megan M Herr, PhD²¹, Erin Eberwein, PharmD^22*, Chenyu Lin, MD²², Brandon Blue²³, Shahzad Raza, MD⁶, Yi Lin, MD, PhD²⁴, Joseph P. McGuirk, DO²⁵, Shebli Atrash, MD²⁶, Douglas W Sborov, MD²⁷, Peter M. Voorhees, MD²⁸, Faiz Anwer, MD⁶, Doris K. Hansen, MD^29*, Krina K. Patel, MD, MSc³⁰, Surbhi Sidana, MD³¹, Andrew J. Cowan, MD^32*, Larry D Anderson Jr., MD, PhD³³, Shambavi Richard, MD¹⁰, Alfred L. Garfall, MD³⁴, Hans C. Lee, MD³⁵ and Jack Khouri, MD⁶

¹Department of Lymphoma & Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
²UT Southwestern Simmons Cancer Center, Dallas, TX
³Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Division of Hematology-Oncology, Medical University of South Carolina, Charleston, SC
⁶Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
⁷H Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁸Department of Hematology and Medical Oncology, Cleveland Clinic, Cleveland, OH
⁹University of Washington, Seattle, WA
¹⁰Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
¹¹Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Santa Clara, CA
¹²University of Utah Huntsman Cancer Institute, Salt Lake City, UT
¹³Department of Hematologic Oncology and Blood Disorders, Atrium Health Levine Cancer Institute, Charlotte, NC
¹⁴University of Kansas Medical Center, Kansas City, KS
¹⁵Division of Hematologic Malignancies & Cellular Therapeutics, University of Kansas Medical Center, Westwood, KS
¹⁶Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
¹⁷Fred Hutchinson Cancer Center, Seattle, WA
¹⁸University of Colorado Cancer Center, Denver, CO
¹⁹Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Palo Alto, CA
²⁰Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX
²¹Roswell Park Comprehensive Cancer Center, Buffalo, NY
²²Duke University Cancer Institute, Durham, NC
²³H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
²⁴Division of Hematology, Mayo Clinic, Rochester, MN
²⁵Division of Hematologic Malignancies & Cellular Therapeutics, University of Kansas Medical Ctr., Westwood, KS
²⁶Levine Cancer Institute, Charlotte, NC
²⁷Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
²⁸Plasma Cell Disorders Section, Department of Hematologic Oncology & Blood Disorders, Levine Cancer Center, Charlotte, NC
²⁹Moffitt Cancer Center, Tampa, FL
³⁰M.D. Anderson Cancer Center, MD Anderson Cancer Center, Houston, TX
³¹Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Stanford, CA
³²University of Washington Fred Hutchinson Cancer Center, Seattle, WA
³³Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX
³⁴Division of Hematology/Oncology, Hospital of the University of Pennsylvania, Philadelphia, PA
³⁵Department of Lymphoma & Myeloma, MD Anderson Cancer Center, Houston, TX

Dor D. Abelman^1,2, Jenna Eagles^1*, Aimee Wong, PhD^3*, Saumil Shah, MSc^3*, Stephanie Pedersen, MSc^1*, Sarah Bridges, MAHS^4*, Cecilia Bonolo De Campos, PhD, MSc, DVM^1*, Darrell White, MD, MSc^5,6, Irwindeep Sandhu, MD⁷, Kevin Song, MD^8,9, Zac McDonald, PhD^10*, Abir Khaled, PhD^10*, Liqiang Yang, PhD^10*, Alli Murugesan, PhD, MSc^11,12*, Anthony Reiman, MD^3,11,13, Suzanne Trudel, MD, MSc^2,14 and Trevor J. Pugh, PhD, FACMG^1,2,15*

¹Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
²Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada
³Department of Biological Sciences, University of New Brunswick, Saint John, NB, Canada
⁴Maritime SPOR SUPPORT Unit, Saint John Regional Hospital, Saint John, NB, Canada
⁵Dalhousie University and QEII Health Sciences Centre, Halifax, NS, CAN
⁶Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada
⁷Cross Cancer Institute, Edmonton, AB, Canada
⁸BC Cancer Agency, Vancouver General Hospital, Vancouver, BC, Canada
⁹Department of Medicine, Division of Hematology, University of British Columbia, Leukemia Bone Marrow Transplant Program of British Columbia and Vancouver General Hospital, Vancouver, BC, Canada, Vancouver, Canada
¹⁰Rapid Novor, Kitchener, ON, Canada
¹¹Faculty of Medicine, Dalhousie University, Saint John, NB, Canada
¹²Department of Nursing and Health Sciences, Faculty of Science, Applied Science and Engineering, University of New Brunswick, Saint John, NB, Canada
¹³Department of Oncology, Saint John Regional Hospital, Saint John, NB, Canada
¹⁴Princess Margaret Cancer Centre, Toronto, ON, Canada
¹⁵Ontario Institute for Cancer Research, Toronto, ON, Canada

Farah Rexha, BS^1*, Joshua Gustine, MD, MPH^2*, Ryan Han, BA^3*, Rie Nakamoto-Matsubara, MD, PhD^4*, Cristina Panaroni, PhD^4*, Rajib Shome, PhD⁵, Valentina Nardi, MD^6*, Andrew R. Branagan, MD⁷, Diana Cirstea, MD^8*, Andrew J. Yee, MD⁹ and Noopur Raje⁵

¹Center for Multiple Myeloma, Cancer Center, Massachusetts General Hospital, Boston, MA
²Massachusetts General Hospital, Boston, MA
³Tufts University School of Medicine, Boston, MA
⁴Center for Multiple Myeloma, Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, MA
⁵Center for Multiple Myeloma, Massachusetts General Hospital, Harvard Medical School, Boston, MA
⁶Department of Pathology, Massachusetts General Hospital, Boston, MA
⁷Center for Multiple Myeloma, Massachusetts General Hospital Cancer Center, Boston, MA
⁸Harvard Medical School, Massachusetts General Hospital Cancer Center, Boston, MA
⁹Massachusetts General Hospital Cancer Center, Boston, MA

Arwa Bohra, MBBS^1*, Saurabh Zanwar, MD^1*, Dragan Jevremovic, M.D., Ph.D^2*, Horatiu Olteanu, M.D., Ph.D.², Wilson I. Gonsalves, MD³, Gregory Otteson^4*, Pedro Horna, MD², Vincent Rajkumar, MD^1* and Shaji Kumar, MD¹

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Division of Hematopathology, Mayo Clinic, Rochester, MN
³Division of Hematology, Mayo School of Graduate Medical Education, Rochester, MN
⁴Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN

Geethika Bodanapu, BA¹, June Corrigan, MS^2*, John Culnan, PhD^2*, Maya Srinivasan, MD, MSc^3,4, Mehar Hora, BS^1*, Alexander Lazzaro, MD^1,3*, Cenk Yildirim, MS^2*, Danne Elbers, PhD^2,4,5*, Deborah Lang, PhD^2,6*, Nhan V. Do, MD, MS^1,2*, Mary T. Brophy, MD^1,2*, Britney Bell, MD^1,3, Raphael E. Szalat, MD, PhD^1,3, Nikhil C. Munshi, MD^2,5,7, Nathanael R. Fillmore, PhD^2,3,5* and Camille V. Edwards, MD^1,3

¹Boston University Chobanian & Avedisian School of Medicine, Boston, MA
²VA Boston Healthcare System, Boston, MA
³Section of Hematology and Medical Oncology, Boston Medical Center, Boston, MA
⁴Boston University Chobanian and Avedisian School of Medicine, Boston, MA
⁵Harvard Medical School, Boston, MA
⁶Department of Dermatology, Boston Medical Center, Boston, MA
⁷Dana-Farber Cancer Institute, The Jerome Lipper Multiple Myeloma Center, Boston, MA

Yukiyasu Kato^1*, Tomotaka Suzuki^1*, Aki Kondo^2*, Naohiro Matsunaga^2*, Takaki Kikuchi^2*, Takashi Kanamori, MD, PhD^2*, Takashi Yoshida, MD^3*, Satoshi Kayukawa^3*, Yu Asao^4*, Hiroki Yano^4*, Hirokazu Sasaki, MD^1*, Arisa Asano, MD, PhD^1*, Shiori Kinoshita, MD, PhD^1*, Tomoko Narita, MD, PhD^1*, Takaomi Sanda, MD, PhD¹, Masaki Ri, MD, PhD^1*, Hirokazu Komatsu, MD, PhD^1* and Shinsuke Iida, MD, PhD⁵

¹Department of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
²Department of Hematology and Oncology, Nagoya City University West Medical Center, Nagoya, Japan
³Department of Hematology and Oncology, Nagoya Memorial Hospital, Nagoya, Japan
⁴Department of Hematology, Kainan Hospital, Yatomi, Japan
⁵Nagoya City University Institute of Medical and Pharmaceutical Sciences, Nagoya, Japan

Evangelos Terpos, MD, PhD¹, Ioannis Ntanasis-Stathopoulos, MD, PhD, MSc^1*, Charalampia Kyriakou, FRCP FRCPath PhD^2*, Carlyn Rose Tan, MD³, Niels Abildgaard, MD, DMSc^4*, Michel Delforge^5*, Dorotea Beatriz Eugenia Fantl, MD⁶, Cristian M Seehaus^7*, Emilie Carneiro^8*, Cristina João, MD, MsC, PhD^9,10* and Saad Z. Usmani, MD¹¹

¹Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
²UCLH Centre for Waldenströms Macroglobulinaemia and Related Conditions, University College London Hospitals NHS Foundation Trust, London, United Kingdom
³Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁴Department of Haematology, Odense University Hospital, Odense, Denmark
⁵University Hospital Leuven, Leuven, Belgium
⁶Hospital Italiano de Buenos Aires, Buenos Aires, BA, ARG
⁷Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
⁸Myeloma Lymphoma Research Group, Champalimaud Experimental Clinical Research Programme, Champalimaud Foundation, Lisbon, Portugal
⁹Champalimaud Foundation, Lisbon, Portugal
¹⁰NOVA Medical School, Universidade Nova de Lisboa, Lisbon, Portugal
¹¹Myeloma Service, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY

Oren Pasvolsky, MD¹, Denái R. Milton, MS^2*, Mark R. Tanner, PhD^3*, Qaiser Bashir, MD³, Samer A. Srour, MD³, Neeraj Y. Saini, MD³, Paul Lin, MD, PhD³, Ashka Patel^3*, Hina N. Khan, MD^3,4*, Jeremy Ramdial, MD³, Yago Nieto, MD, PhD³, Guilin Tang, MD, PhD^5*, Asad Haider, MD^3*, Yosra M. Aljawai, MD, MS³, Saqib Ahmed, MD^3*, Partow Kebriaei, MD³, Hans C. Lee, MD¹, Christine Ye, MD^1*, Krina K. Patel, MD, MSc¹, Sheeba K. Thomas, MD¹, Robert Z. Orlowski, MD, PhD¹, Richard E. Champlin, MD³, Elizabeth J. Shpall, MD³ and Muzaffar H. Qazilbash, MD³

¹Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Hematology/Oncology, McGovern Medical School, The University of Texas, Health Sciences Center at Houston, Houston, TX
⁵Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX

Yang Xu^1*, Yili Fan^1*, Luyao Wang^1*, Jiawei Zhang^1*, Boxiao Chen^1*, Luyu Yang^1* and Xuzhao Zhang^2*

¹the Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
²Department of Hematology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, China

Fidelia Ida^1*, Bharat Ramakrishna^1*, Kaz Nasserinejad^2*, Adriana Radu^1*, John-Philip Lawo^1*, Xiang Zhang^1*, David Gardiner^1*, Lara Yoon^3*, Elizabeth C. Dabrowski^3*, John Shen^3*, Monica Iyer^3*, Hannah Kreisberg^3*, Gabriela Espinoza^1*, Zainab Shahid^4* and Sergio A. Giralt, MD⁴

¹CSL Behring LLC, King of Prussia, PA
²Biostatistics Department, Data Sciences, Safety, and Medical (DSSM), IQVIA Inc., Durham
³Aetion, Inc., New York, NY
⁴Memorial-Sloan Kettering Cancer Center, New York, NY

Sahin Sarihan, BSc^1*, Roisin McAvera, PhD^2*, Catherine Duane, MD, MSc, BSc^2*, Philip T Murphy^3*, Quinn John, PhD^4*, Rowan Kuiper^5*, Ian Overton, PhD^6* and Siobhan V Glavey¹

¹Departments of Haematology and Pathology, Beaumont RCSI Cancer Centre, Dublin, Ireland
²Beaumont RCSI Cancer Centre, Departments of Haematology and Pathology, Dublin, Ireland
³Department of Haematology, Beaumont RCSI Cancer Centre, Dublin, Ireland
⁴Beaumont RCSI Cancer Centre, Department of Haematology, Dublin, Ireland
⁵SkylineDx, Rotterdam, Netherlands
⁶Patrick G Johnston Centre for Cancer Research, Queens University Belfast, School of Medicine Dentistry and Biomedical Science, Belfast, United Kingdom

Zhaochen Zhang, MD^1*, Zhangzhen Shi^2*, Di Zhou^3*, Xinmei Dang, MD^1*, Xiangyi Guo^4* and Lintao Bi, MD, PhD⁵

¹The Third Bethune Hospital of Jilin University, Changchun, China
²Jilin University, Changchun, CHN
³Department of Oncology and Hematology, China-Japan Union Hospital, Jilin University, Changchun, China
⁴China-Japan Union Hospital of Jilin University, Changchun, AL, China
⁵Department of Hematology, China-Japan Union Hospital of Jilin University, Changchun, AL, China

Beatriz Astibia Mahillo, MD^1*, María-Jesús Blanchard, MD, PhD^1*, Miguel Piris Villaespesa, MD, PhD^1*, Pablo Palomo Rumschisky, MD^1*, Jesús Villarrubia Espinosa, MD^1*, Valentín García Gutiérrez Sr.¹, Ana Jiménez, MD^1*, Mónica García-Cosío^2*, Ernesto Roldán Santiago^3*, Eulalia Rodríguez Martín^3*, María Talavera Yagüez^4*, Gemma Moreno Jiménez^1*, Javier López^1* and Fernando Martín Moro^1*

¹Hematology, Hospital Universitario Ramón y Cajal, Madrid, Spain
²Pathology, Hospital Universitario Ramón y Cajal, Madrid, Spain
³Immunology, Hospital Universitario Ramón y Cajal, Madrid, Spain
⁴Genetics, Hospital Universitario Ramón y Cajal, Madrid, Spain

Julia Grace Reinke^1*, Peng Peng^2*, Daniela Nicoleta Petrusca, PhD¹, Kanita Chaudhry, BS^3*, Louise Carlson^1*, Christopher Rolf Schorr^1,4 and Kelvin P. Lee, MD^5,6,7

¹Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN
²Indiana University Simon Cancer Center, Indianapolis, IN
³Roswell Park Comprehensive Cancer Center, Buffalo, NY
⁴Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN
⁵Indiana University School of Medicine, Indianapolis, IN
⁶Melvin and Bren Simon Comprehensive Cancer Center, Division of Hematology and Oncology, Indiana University School of Medicine, Indianapolis, IN
⁷Melvin and Bren Simon Comprehensive Cancer Center, INDIANA UNIVERSITY, INDIANAPOLIS, IN

Kuldeepsinh Atodaria, MD¹, Keerthi Sripathi, MD^2*, Samyukta Varma, MD^3*, Tarun Parvataneni, MD^4*, Navanita Biswas, MD^5*, Bhavya Raja Gopal Yarlagadda, MD^6*, Megha Panchal, MBBS^7*, Hashwin Pilathodan, MBBS^8*, Janani Arunachalam, MBBS^9*, Shalin Rawal, MBBS^10*, Jujhar Sandhu, MD^11* and Urvish Patel, MD^12*

¹Tower Health Reading Hospital, West Reading, PA
²Arkansas College of Osteopathic Medicine Program, Fort Smith, AR
³Marshfield Clinic, Marshfield, WI
⁴Aiken Regional Medical Center, Aiken, SC
⁵Tower Health Reading Hospital, west reading
⁶MUSC Kershaw medical center, camden
⁷GMERS Medical College,sola, Odhav, AL, India
⁸Coimbatore Medical College, coimbatore, India
⁹University of Connecticut, Farmington, CT
¹⁰NYMC st. Mary's General Hospital and Saint Clare's Health, denville
¹¹Ampla Health, yuba
¹²Icahn School Medicine at Mount Sinai, Jersey City, NJ

Meletios Dimopoulos, MD¹, Thierry Facon, MD², Meral Beksac^3*, Ludek Pour, PhD^4*, Roman Hajek, MD, PhD⁵, Zhuogang Liu^6*, Jiri Minarik⁷, Philippe Moreau, MD, PhD^8*, Joanna Romejko-Jarosinska, MD, PhD^9*, Ivan Špička^10*, Vladimir I. Vorobyev, PhD^11*, Britta Besemer, MD^12*, Tadao Ishida¹³, Wojciech Janowski, FRCPA, FRACP¹⁴, Sevgi Kalayoglu Besisik^15*, Gurdeep Parmar, MBBS^16*, Pawel Robak^17*, Elena Zamagni, MD^18*, Hartmut Goldschmidt, MD¹⁹, Thomas Martin, MD²⁰, Salomon Manier, MD, PhD²¹, Mohamad Mohty, MD, PhD²², Robert Z. Orlowski, MD, PhD²³, Erin Comerford, MSc^24*, Claire Tian^25*, Jérôme Msihid, MSc^26*, Feng Lin^27*, Stephanie Rhoten, PhD^28* and Xavier. P Leleu^29*

¹Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece
²University of Lille, CHU Lille, Service des Maladies du Sang, Lille, France
³Istinye University Ankara Liv Hospital, Ankara, Turkey
⁴University Hospital Brno, Brno, Czech Republic
⁵University Hospital Ostrava and University of Ostrava, Ostrava, Czech Republic
⁶Department of Hematology, Shengjing Hospital of China Medical University, Shenyang, China
⁷Department of Hemato-Oncology, University Hospital Olomouc and Faculty of Medicine and Dentistry, Palacky University Olomouc, Olomouc, Czech Republic, Olomouc, Czech Republic
⁸University Hospital Hôtel-Dieu, Nantes, France
⁹Department of Lymphoid Malignancies, Marie Sklowdoska-Curie National Research Institute of Oncology, Warszawa, Poland
¹⁰Charles University and General Hospital in Prague, Prague, Czech Republic
¹¹Department of Lymphoid Malignancies Maria Sklodowska -Curie National Research Institute Warszawa, Poland, Warszawa, Poland
¹²Department of Hematology, Oncology, Immunology and Rheumatology, University Hospital of Tuebingen, Tuebingen, Germany
¹³Department of Hematology, Japanese Red Cross Medical Center, Tokyo, Japan
¹⁴Calvary Mater Newcastle, Waratah, NSW, AUS
¹⁵İstanbul University Rectorate 34452 Beyazıt/Fatih/İstanbul, Istanbul, Turkey
¹⁶Wollongong Hospital, Wollongong, Australia, Wollongong, Australia
¹⁷Department of General Hematology, Copernicus Memorial Hospital, Comprehensive Cancer Center and Traumatology, Łódź, Poland
¹⁸IRCCS Azienda Ospedaliero-Universitaria di Bologna, Istituto di Ematologia Seràgnoli, Bologna, Italy
¹⁹Internal Medicine V, GMMG - Study Group at University Hospital Heidelberg, Heidelberg, Germany
²⁰Department of Hematology, University of California at San Francisco, San Francisco, CA
²¹Lille University Hospital, Lille, France
²²Hematology Dpt, Hopital Saint-Antoine, University UPMC, INSERM, Paris, France
²³Department of Lymphoma & Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
²⁴Sanofi, 450 Water St Cambridge (U.S.) Massachusetts 02141 United States of America, Cambridge, MA
²⁵Sanofi, 5-7 Floor, 112 Jian Guo Rd - Chaoyang District Beijing, Beijing, China
²⁶Sanofi, Gentilly, France
²⁷Sanofi, Cambridge, MA
²⁸Patient Centered Solutions at IQVIA, San Francisco, California, United States, San Francisco, CA
²⁹Hematology, CHU, University, Poitiers, France, Poitiers, France

Joseph S Hong Jr., jhong20@mgh.harvard.edu^1*, Baijun Zhou, MHS^1*, Andrew J. Yee, MD^2,3 and Sara Barmettler, MD^1,2*

¹Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA
²Harvard Medical School, Boston, MA
³Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA