Jun Ma, PhD^1*, Michael P Randall, MD², Ming Lu^2*, Lingjing Chen, PhD^2*, Huimin Geng, PhD^3*, Aishwarya Kumar^1*, Saloni Malla, PhD^1*, Mark Noviski, PhD^1*, Ryan Rountree, PhD^1* and James L. Rubenstein, MD, PhD⁴

¹NURIX Therapeutics, San Francisco, CA
²Hematology/Oncology, Department of Medicine, University of California, San Francisco, San Francisco, CA
³Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA
⁴Hematology/Oncology, Department of Medicine, Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA

Vinodh Pillai, MD^1*, David Smith, PhD^2*, Anna Eichinger^3,4*, Andrew Rech^5*, Julia Wang^5*, Eduardo Esteva^6*, Arta Seyedian^7*, Xiaoxu Yang^8*, Mei Zhang^9*, Dan Martinez^10*, Kai Tan, PhD¹¹, Minjie Luo, PhD, FACMG^12*, Christopher Y. Park, MD, PhD¹³ and Boris Reizis, PhD^14*

¹University of Pennsylvania, Philadelphia, PA
²Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA
³New York University Grossman School of Medicine, New York, NY
⁴Department of Pediatrics, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-Universität München, Munich, Germany
⁵University of Pennsylvania, Philadelphia
⁶New York University Grossman School of Medicine, New York
⁷Children's Hospital of Philadelphia, Philadelphia, PA
⁸The Children's Hospital of Philadelphia, Philadelphia, PA
⁹The Children's Hospital of Philadelphia, Philadelphia
¹⁰The Children's Hospital of Philadelphia, Phildelphia
¹¹Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA
¹²Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, Philadelphia
¹³Department of Pathology, New York University School of Medicine, New York, NY
¹⁴New York University School of Medicine, New York, NY

Marina Bacac, PhD^1*, Johannes Sam, PhD^2*, Won Seog Kim, MD^3*, Gareth P. Gregory, MBBS(Hons), PhD, FRACP, FRCPA⁴, Matthew Ku, MBBS, PhD^5*, Sylvia Herter, PhD^1*, Christian Klein, PhD¹, Pablo Umana, PhD¹, Stephen Simko^6*, Victor Orellana-Noia^6*, Linda Lundberg^7* and Alessia Bottos, PhD^7*

¹Roche Innovation Center Zürich, Pharma Research & Early Development, Zürich, Switzerland
²Roche Innovation Center Zürich, Pharma Research & Early Development, Zurich, Switzerland
³Samsung Medical Center, Division of Hematology-Oncology, Department of Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of (South)
⁴School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia
⁵St Vincent's Hospital, University of Melbourne, Melbourne, Australia
⁶Genentech, Inc., South San Francisco, CA
⁷F. Hoffmann-La Roche Ltd, Basel, Switzerland

Johannes Duell, MD^1*, Diana Alvarez Arias^2*, Hilka Rauert-Wunderlich^1*, Florian Eisele^1*, Alla Volgina^2*, Beth Rumberger^2*, Thomas Stauffer Larsen, MD, PhD^3* and Andreas Rosenwald^1*

¹University of Wurzburg, Wurzburg, Germany
²Incyte Corporation, Wilmington, DE
³Odense University Hospital, Odense, Denmark

Dimitra Karagkouni, PhD^1,2,3*, Maria J. J. Fernandez Turizo, MD⁴, Nikolaos Kalavros^1,2,3,5*, Sean M McCabe, BS^6*, Alexandra W Lenart, BA^7*, Shivani Nanda^1,2,3*, Athanasios Ploumakis^1,2,3,5*, Antonella Amaral^2,5*, Anna B Rider, BSc^8*, Aliyah R. Sohani, MD^3,6*, Mwanasha H. Merrill, MD⁹, Eric D. Jacobsen, MD¹⁰, Maria Elena Cabrera, MD^11*, Pablo Villegas^12*, Ioannis S Vlachos, PhD^1,2,3,5* and Salvia Jain, MD^2,3,6

¹Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA
²Broad Institute of Harvard and MIT, Cambridge, MA
³Harvard Medical School, Boston, MA
⁴Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Brookline, MA
⁵Spatial Technologies Unit, Harvard Medical School Initiative for RNA Medicine, Beth Israel Deaconess Medical Center, Boston, MA
⁶Division of Hematology and Oncology, Department of Medicine, Massachusetts General Hospital Cancer Center, Boston, MA
⁷Department of Medicine, Massachusetts General Hospital, Boston, MA
⁸Department of Pathology, Massachusetts General Hospital, Boston, MA
⁹Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA
¹⁰Dana Farber Cancer Institute, Boston, MA
¹¹Hematology Department, Hospital del Salvador, Santiago, Chile
¹²Pathology Department, Hospital del Salvador, Santiago, Chile

Troy Noordenbos^1,2*, Joseph G. Schroers-Martin, MD¹, Mark P. Hamilton, MD, PhD^3,4, Soyeong Jun, PhD^5*, Takeshi Sugio, MD, PhD^1,2*, Brian J. Sworder, MD, PhD⁶, Chloé Beate Steen, PhD^7*, Mari Olsen, BS^1*, Chih Long Liu, PhD^1*, Aaron Newman^8*, Brooke Howitt, MD, PhD^9*, Yasodha Natkunam, MD, PhD⁹, David B. Miklos, MD, PhD^3,10, Maximilian Diehn, MD, PhD^5*, Matthew J. Frank, MD, PhD^2,3,10 and Ash A. Alizadeh, MD, PhD^1,2

¹Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, CA
²Stanford Cancer Institute, Stanford University, Stanford, CA
³Stanford Cancer Institute, Center for Cancer Cell Therapy, Stanford University, Stanford, CA
⁴Department of Medicine, Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University, Stanford, CA
⁵Department of Radiation Oncology, Stanford University, Stanford, CA
⁶Division of Hematology and Oncology, University of California, Irvine, Irvine, CA
⁷Oslo University Hospital, Oslo, Norway
⁸Stanford University, Stanford, CA
⁹Department of Pathology, Stanford University, Stanford, CA
¹⁰Division of Blood and Marrow Transplantation and Cellular Therapy, Stanford University School of Medicine, Palo Alto, CA

Lei Nie, MD^1,2*, Vivian Jiang, PhD¹, Yang Liu, Ph.D^1,3*, Tianci Zhang, MS^1*, Hong Kim, PhD^4*, Jovanny Vargas^5*, Qingsong Cai, PhD^3*, Selvi Thirumurthi, MD^6*, David Santos^4* and Michael Wang, MD^1,7,8

¹Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, HOUSTON, TX
³The University of Texas MD Anderson Cancer Center, Houston, TX
⁴UT MD Anderson Cancer Center, Houston, TX
⁵Lymphoma Myeloma, The University of Texas MD Anderson Cancer Center, houston, TX
⁶Gastroenterology, The University of Texas MD Anderson Cancer Center, houston, TX
⁷Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
⁸The University of Texas MD Anderson Cancer Center, Department of Lymphoma and Myeloma, Houston, TX

Patrick Nylund, PhD^1*, Kossi D Abalo, PhD^1,2*, Saima Zubair, PhD^1*, Eirini Voutsinou^1*, Tove Selvin^1*, Ann-Marie Ly, MD^1*, Anna Nikkarinen, MD^3*, Mattias Berglund, PhD^4*, Daniel Molin^4*, Gunilla Enblad, MD, PhD^4*, Peter Hollander, MD, PhD^4*, Mats Hellström, MD, PhD^4* and Ingrid Glimelius, MD, PhD^1,2

¹Department of Immunology, Genetics and Pathology, Cancer Precision Medicine Unit, Uppsala University, Uppsala, Sweden., Uppsala University, Uppsala, Sweden
²Department of Medicine, Clinical Epidemiology Division, Karolinska Institute, Stockholm, Sweden
³Department of Immunology, Genetics and Pathology, Cancer Precision Medicine Unit, Uppsala University, Uppsala, Sweden
⁴Department of Immunology, Genetics and Pathology, Cancer Immunotherapy Unit, Uppsala University, Uppsala, Sweden

Meijuan Wu^1*, Xi Chen^2*, Jialiang Lu^3,4*, Weihao Zhuang^3*, Chang He^5*, Cong Li^2*, Haifeng Yu^2*, Tao Lei^2*, Xiaowu Dong, PhD^3*, Jianpeng Sheng, PhD^5* and Haiyan Yang, PhD⁶

¹Pathology Department, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, China
²Lymphoma Department, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, China
³Hangzhou Institute of Innovative Medicine, Institute of Drug Discovery and Design, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, China
⁴Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, China
⁵College of Artificial Intelligence, Nanjing University of Aeronautics and Astronautics, Nanjing, China
⁶Department of Lymphoma, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, China

Marie Hairing Enemark^1*, Maja Lund Jensen, MSc^1*, Maja Dam Andersen, MD^2*, Trine Plesner^3*, Stephen Hamilton-Dutoit^2* and Maja Ludvigsen^1,4

¹Department of Hematology, Aarhus University Hospital, Aarhus N, Denmark
²Aarhus University Hospital, Aarhus N, Denmark
³Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
⁴Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark

Daisy Lin, MS^*, Vanessa Spires^*, Jeremy Gale, MS^*, Nathan Cheadle, MS^*, Tine Casneuf, PhD^*, Gregg Masters, MS^*, Lisa Grimm, BS^*, Omar Jabado, PhD^*, Tahamtan Ahmadi, MD, PhD^*, Mark Fereshteh, PhD^*, Maria Jure-Kunkel, PhD, DVM^*, Andrew J. Steele, PhD^* and Jordan Blum, PhD^*

Genmab, Plainsboro, NJ

Ioanna Xagoraris, MD^1,2, Ying Yang, PhD^3*, Dora Trogrlic, MSc^3*, Alma Mansson^4*, Christina Plastira, MD^3*, Vasiliki Leventaki, MD^5*, Hong Qian, PhD⁶, Andreas Lundqvist, PhD^3* and George Z. Rassidakis, MD, PhD^3,7*

¹Department of Oncology-Pathology, Karolinska Institute, Solna, Stockholm, Sweden
²Department of Pathology and Cancer Diagnostics, Karolinska University Hospital, Stockholm, Sweden
³Department of Oncology-Pathology, Karolinska Institute, Stockholm, Sweden
⁴Center for Hematology and Regenerative Medicine (HERM), Department of Medicine, Huddinge, Karolinska Institute, Stockholm, Quebec, Sweden
⁵Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX
⁶Center for Hematology and Regenerative Medicine (HERM), Department of Medicine Huddinge, Karolinska Institute, Stockholm, Sweden
⁷Department of Oncology-Pathology, Karolinska University Hospital, Stockholm, Sweden

Elisavet Vlachonikola, PhD^1*, Antonios Mingos^1,2*, Philip Rock^3*, Glykeria Gkoliou^1,2*, Marina Gerousi^1*, Maria Fitopoulou^1,2*, Nikolaos Pechlivanis^1,4*, Maria Karipidou^1*, Anastasia Iatrou^1,2*, Malama Galanou^1,5*, Efthalia Karamanli^1*, Nikolaos Vastarouchas^1*, Charles C Chu, PhD⁶, Clive S Zent, MD³, Richard Burack³, Anastasia Chatzidimitriou^1,7* and Kostas Stamatopoulos^1,7*

¹Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece
²Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece
³Departments of Pathology and Laboratory Medicine, Medicine, and Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA
⁴Department of Genetics, Development and Molecular Biology, School of Biology, Aristotle University of Thessaloniki, Thessaloniki, Greece
⁵Department of Biological Applications and Technology, University of Ioannina, Ioannina, Greece
⁶Departments of Pathology and Laboratory Medicine, Medicine, and Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY
⁷Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden

Anath Lionel, MD, PhD¹, Naishu Kui^2*, Ryan Sun^2*, Eslam Aboismail, MD^3*, Sanjit Om Tewari, MD^4*, Ajlan Al Zaki, MD, PhD⁵, Sushanth Gouni, MD⁶, Preetesh Jain, MD, MBBS, PhD, DM⁶, Dai Chihara, MD, PhD⁶, Swaminathan P Iyer, MD^6*, Michael Wang, MD⁶, Ranjit Nair, MD^6*, Luis Enrique Malpica Castillo, MD⁶, Hun Ju Lee, MD⁶, Chijioke Nze, MD, MPH⁶, Luis E. Fayad, MD³, Frederick Hagemeister^6*, Maria Alma Rodriguez, MD^6*, Amy A. Ayers, MPH^6*, Cristina Gutierrez^7*, Gabriela Rondon, MD⁸, Fareed Khawaja, MBBS⁹, Partow Kebriaei, MD⁸, Elizabeth J. Shpall, MD⁸, Christopher R. Flowers, MD, MS⁶, Jason R. Westin, MD⁶, Paolo Strati, MD⁶, Wei WANG^10*, Sa A. Wang, MD¹⁰, Sairah Ahmed, MD⁶ and Sattva S. Neelapu, MD⁶

¹Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Oakville, ON, Canada
²Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX
³The University of Texas MD Anderson Cancer Center, Houston, TX
⁴Department of Nuclear Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Department of Lymphoma/Myeloma and Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX
⁶Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷Department of Critical Care, The University of Texas MD Anderson Cancer Center, Houston, TX
⁸Department of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX
⁹Department of Infectious Diseases, The University of Texas MD Anderson Cancer Center, Houston, TX
¹⁰Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX

Marina Gerousi^1*, Maria Fitopoulou^1,2*, Malama Galanou^1,3*, Philip Rock^4*, Georgios Karakatsoulis^1*, Anastasia Anastasiadou^1*, Maria Karipidou^1*, Anastasia Iatrou^1,2*, Efthalia Karamanli^1*, Nikolaos Vastarouchas^1*, Paolo Ghia, MD, PhD^5,6, Charles C Chu, PhD⁷, Clive S Zent, MD⁴, Richard Burack⁴, Anastasia Chatzidimitriou^1,8* and Kostas Stamatopoulos^1,9

¹Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece
²Department of Molecular Biology and Genetics, Democritus University of Thrace, Alexandroupolis, Greece
³Department of Biological Applications and Technology, University of Ioannina, Ioannina, Greece
⁴Departments of Pathology and Laboratory Medicine, Medicine, and Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA
⁵Division of Experimental Oncology, B cell neoplasia Unit, IRCCS Ospedale San Raffaele, Milan, Italy
⁶Università Vita-Salute San Raffaele, Milan, Italy
⁷Departments of Pathology and Laboratory Medicine, Medicine, and Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY
⁸Department of Molecular Medicine and Surgery, Karolinska Institute, Stockholm, Sweden
⁹Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden

Ruifeng Sun^1*, Jaewoong Lee, PhD^1,2*, Mark E Robinson, PhD^1*, Kohei Kume, PhD^1*, Chuanzong Zhan, PhD^1*, Zhangliang Cheng, BSc^1*, Kadriye Nehir Cosgun, PhD^1*, Lai N Chan, PhD¹, Etienne Leveille, MD^1*, Shalin Kothari, MD^1*, Samuel G. Katz, MD-PhD^3*, Ning Ma, PhD^4*, Vivasvan S Vykunta^5*, Brian Shy, MD-PhD^6*, Daniel J Hodson, MD-PhD⁷, Alexander Marson, MD-PhD^8*, Nagarajan Vaidehi, PhD^4* and Markus Müschen, MD¹

¹Center of Molecular and Cellular Oncology, Yale University, New Haven, CT
²School of Biosystems and Biomedical Sciences, Korea University, Seoul, Korea, Republic of (South)
³Department of Pathology, Yale School of Medicine, New Haven, CT
⁴Department of Systems Biology, City of Hope Comprehensive Cancer Center, Duarte, CA
⁵Department of Medicine, University of California San Francisco, San Francisco, CA
⁶Department of Laboratory Medicine, University of California San Francisco, San Francisco, CA
⁷Wellcome-MRC Cambridge Stem Cell Institute and Department of Haematology, University of Cambridge, Cambridge, United Kingdom
⁸Department of Medicine, University of California, San Francisco, San Francisco, CA

Min Liu^1,2*, Liang Hong^1*, Shruti Sridhar^1*, Patrick Jaynes^1*, Chartsiam Tipgomut, PhD^1*, Limei Poon^3,4*, Sanjay De Mel, BSc, FRCPath, MRCP^3,4*, Joanne Shu Xian Lee^4,5*, Jayalakshmi .^5*, Siok-Bian Ng^4,6*, Char Loo Tan^6*, Wee-Joo Chng^1,5,7 and Anand Devaprasath D. Jeyasekharan, MBBS, MRCP, PhD^1,3,4,8*

¹Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
²Department of Radiation Oncology, Chongqing University Cancer Hospital, Chongqing, China
³Department of Haematology-Oncology, National University Cancer Institute, Singapore, National University Health System, Singapore, Singapore
⁴NUS Centre for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⁵Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore
⁶Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⁷Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⁸Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

Jenny Coelho¹, Sophia Maharry Roush^2*, Samantha Beck³, Amon Chirwa^4*, Edwards Kasonkanji, MPH^4*, Tamiwe Tomoka, MD^5*, Jonathan Galeotti^6*, Satish Gopal, MD, MPH^7,8*, Matthew S Painschab, MD⁴ and Yuri D. Fedoriw, MD^4,9

¹Department of Laboratory Medicine, UNC Chapel Hill, Chapel Hill, NC
²Pathobiology & Translational Science, University of North Carolina at Chapel Hill, Chapel Hill, NC
³Pathobiology & Translational Science, University of North Carolina at Chapel Hill, Carrboro, NC
⁴UNC Project-Malawi, Lilongwe, Malawi
⁵Kamuzu Central Hospital, Lilongwe, Lilongwe, MWI
⁶University of North Carolina, Chapel Hill, NC
⁷UNC Project-Malawi, Lilongwe, MWI
⁸National Cancer Institute, Rockville, MD
⁹Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC

Fiona Swain^1,2*, Melinda Burgess, PhD^2,3*, Sarah Kempe^4*, Muhammed B. Sabdia, BSc⁵, Andrea S Henden, MBBS^6,7,8, Joel Wight, MBBS, FRACP, FRCPA, DMedSc^9,10*, Eliza A. Hawkes, MD^11,12, Howard Mutsando, MBChB, FRACP, FRCPA^13,14*, Dipti Talaulikar, PhD, FRACP, FRCPA, MBBS^15,16, Lilia Merida de Long^4*, Simone Birch, MBBS^17*, Penelope Wyche, MBBS^18*, Zachary Hawula, PhD^2*, Rakin Chowdhury, MD^2,19*, Maher K. Gandhi, PhD, FRACP, FRCPath^5,20 and Colm Keane, MD^2,21

¹Department of Haematology, Princess Alexandra Hospital, Woolloongabba, Australia
²Frazer Institute, University of Queensland, Brisbane, QLD, Australia
³Department of Haematology, Princess Alexandra Hospital, Brisbane, QLD, Australia
⁴Frazer Institute, University of Queensland, Brisbane, Australia
⁵Mater Research Institute, University of Queensland, Brisbane, QLD, Australia
⁶Translational Cancer Immunotherapy, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia
⁷Department of Haematology and Bone Marrow Transplant, Royal Brisbane and Women's Hospital, Brisbane, QLD, Australia
⁸Faculty of Medicine, University of Queensland, Brisbane, Australia
⁹Department of Haematology & Bone Marrow Transplantation, Townsville University Hospital, Townsville, Australia
¹⁰School of Medicine, James Cook University, Townsville, Australia
¹¹School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
¹²Austin Health, Olivia Newton-John Cancer Research & Wellness Centre, Melbourne, Australia
¹³University of Queensland Rural Clinical School, Toowoomba, QLD, Australia
¹⁴Toowoomba Hospital, Toowoomba, QLD, Australia
¹⁵Department of Diagnostic Genomics, Canberra Health Services, Canberra, Australia
¹⁶College of Health and Medicine, Australian National University, Red Hill, Australia
¹⁷Pathology Queensland, Brisbane, AUS
¹⁸Pathology Queensland, Brisbane, Australia
¹⁹Department of Haematology, Princess Alexandra Hospital, Fairfield Gardens, QLD, Australia
²⁰Department of Haematology, Princess Alexandra Hospital, Brisbane, Australia
²¹Department of Haematology, Princess Alexandra Hospital, Woolloongabba, Qld, Australia