Michelle P. Aranha, PhD^1,2,3*, Omar Nadeem, MD⁴, Robert A. Redd, MS^5*, Michael Timonian, MD^1,2,3*, Sophie Magidson, BS^2*, Elizabeth D. Lightbody, PhD^1,2,3, Jean-Baptiste Alberge, PhD^1,2,3, Ting Wu, MS^1*, Junko Tsuji, PhD^1*, Luca Bertamini, MD^2*, Ankit K. Dutta, PhD^1,2,3*, Habib El-Khoury, MD^2*, Mark Bustoros, MD⁶, Jacob Laubach², Giada Bianchi, MD⁷, Elizabeth K. O'Donnell, MD², Kenneth C. Anderson, MD^2,3, Gad Getz, PhD^1*, Lorenzo Trippa, PhD^5*, Paul G. Richardson^2,3, Romanos Sklavenitis-Pistofidis, MD^1,2,3 and Irene Ghobrial, MD^1,2,3

¹Broad Institute of MIT and Harvard, Cambridge, MA
²Dana-Farber Cancer Institute, Boston, MA
³Harvard Medical School, Boston, MA
⁴Center for Early Detection and Interception of Blood Cancers, Dana-Farber Cancer Institute, Boston, MA
⁵Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
⁶Division of Hematology & Medical Oncology, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY
⁷Amyloidosis Program, Division of Hematology, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

Noa Biran, MD^1*, Binod Dhakal, MBBS², Ruben Niesvizky, MD³, Suzanne Lentzsch, MD, PhD⁴, John T Mckay, MD^5*, David H. Vesole, MD, PhD^6,7, Ajay K. Nooka, MD, MPH⁸, Barry Paul, MD, MS⁹, Parameswaran N. Hari, MD, MBBS¹⁰, Silvia D'Ambrosi^11*, Rowan Kuiper^11*, Martin H van Vliet, PhD^11*, David S. Siegel, MD, PhD¹, Saad Z. Usmani, MD¹² and Frits van Rhee, MD, PhD¹³

¹Hackensack University Medical Center, Hackensack, NJ
²Division of Hematology and Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI
³Division of Hematology and Medical Oncology, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY
⁴Columbia University Medical Center, New York, NY
⁵Wake Forest University School of Medicine, Winston-Salem, NC
⁶Multiple Myeloma Division, John Theurer Cancer Center, Hackensack Meridian Health, Hackensack, NJ
⁷Lombardi Comprehensive Cancer Center, Medstar Georgetown Medical Center, Washington, DC, DC
⁸Winship Cancer Institute of Emory University, Atlanta
⁹Department of Hematologic Oncology & Blood Disorders, Levine Cancer Institute, Atrium Health Wake Forest University School of Medicine, Charlotte, NC
¹⁰The Medical College of Wisconsin, Brookfield, WI
¹¹SkylineDx, Rotterdam, Netherlands
¹²Myeloma Service, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
¹³Myeloma Center, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR

Henry Becerra, MD¹, Emmanuel Bugarin-Estrada^2*, Ruben Niesvizky, MD³, Roger Pearse, MD, PhD^4*, Jorge Monge, MD⁴ and Mateo Mejia Saldarriaga, MD^5,6

¹Department of Medicine, Brookdale University Hospital and Medical Center, Brooklyn, NY
²Internal Medicine, University of Miami Health System, Miami, FL
³Division of Hematology and Medical Oncology, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY
⁴Division of Hematology & Medical Oncology, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY
⁵Division of Hematology & Medical Oncology, Weill Cornell/New York Presbyterian Hospital, New York, NY
⁶Division of Hematology & Medical Oncology, Weill Cornell Medicine/New York Presbyterian Hospital, NEW YORK, NY

Yuka Uesugi^1,2*, Daisuke Miura^3*, Ami Inokuchi^4*, Daisuke Ikeda^5,6*, Rikako Tabata, M.D.^5*, Kentaro Narita^1*, Masami Takeuchi, M.D.^5* and Kosei Matsue, M.D., Ph.D.⁵

¹Division of Hematology/Oncology, Kameda Medical Center, Chiba, Japan
²Division of Hematology, Department of Internal Medicine, Showa university Fujigaoka hospital, Kanagawa, Japan
³Division of Hematology, Kimitsu Chuo Hospital, Chiba, Japan
⁴Division of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan
⁵Division of Hematology/Oncology, Kameda Medical Center, Kamogawa, Chiba, Japan
⁶Department of Hematology and Oncology, Okayama University Hospital, Okayama, Japan

Wenqiang Yan^1*, Lihui Shi^2*, Jingyu Xu^3*, Lingna Li^4*, Jian Cui^5*, Chenxing DU^3*, Tengteng Yu^6*, Shuaishuai Zhang, MD^6*, Rui Lv^7*, Weiwei Sui, MD^3*, Shuhui Deng^8*, Yan Xu, MD^9*, Dehui Zou^3*, Lu-Gui Qiu, M.D.³, Mu Hao, MD^3* and Gang An^3*

¹State Key Laboratory of Experimental Hematology, State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood, TIANJIN, China
²State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical Colleg, Tianjin, Tianjin, China
³State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology& Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
⁴State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical Colleg, Tianjin, CHN
⁵State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, TIANJIN, China
⁶State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
⁷State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences&Peking Union Medical College, Tianjin, CHN
⁸State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical Colleg, Brookline, MA
⁹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Boston, MA

Mohamad Mohty, MD, PhD¹, Nizar J. Bahlis, MD², Ajay K. Nooka, MD, MPH³, Marco DiBonaventura^4*, Joseph C. Cappelleri, PhD^5* and Umberto Conte, PharmD^4*

¹Sorbonne University, Hôpital Saint-Antoine, and INSERM UMRs938, Paris, France
²Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada
³Winship Cancer Institute of Emory University, Atlanta
⁴Pfizer Inc, New York, NY
⁵Pfizer Inc, Groton, CT

Tomas Jelinek, MD, PhD^1*, David Zihala^2,3*, Aintzane Zabaleta, PhD^4*, Ioannis V Kostopoulos, PhD^5*, Ondrej Soucek^6*, Ondrej Venglar^3*, Cristina Moreno^7*, Despina Fotiou, MD^8*, Eva Radova^3,9*, Luis-Esteban Tamariz-Amador, MD^7*, Foteini Theodorakakou, MD^8*, Ludmila Muronova^2,10*, Andrea Manubens, PhD^11*, Ourania Tsitsilonis, MD, PhD^5*, Tereza Popkova, MD^2,10*, Lucie Broskevicova^3,9*, Jana Mihalyova^3,9*, Tereza Sevcikova^3*, Jesús F. San-Miguel, MD, PhD¹², Meletios Dimopoulos, MD⁸, Paula Rodríguez-Otero, MD, PhD^4*, Jakub Radocha, MD, PhD¹³, Efstathios Kastritis, MD^14*, Bruno Paiva, PhD^15* and Roman Hajek, MD, PhD^9,16

¹Department of Hematooncology, University Hospital Ostrava and Faculty of Medicine University of Ostrava, Ostrava, Czech Republic
²Department of Haematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
³Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
⁴Clínica Universidad de Navarra. Centro de Investigación Médica Aplicada., Pamplona, Spain
⁵Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece
⁶Department of Immunology, University Hospital Hradec Kralove and Faculty of Medicine in Hradec Kralove, Charles University, Hradec Kralove, Czech Republic, Hradec Kralove, Czech Republic
⁷Cancer Center Clinica Universidad de Navarra (CCUN), Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IdiSNA), CIBER-ONC numbers CB16/12/00369 and CB16/12/00489, Pamplona, Spain
⁸Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
⁹Department of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
¹⁰Department of Haematooncology, University Hospital Ostrava, Ostrava, Czech Republic
¹¹Clínica Universidad de Navarra, Cancer Center Clínica Universidad de Navarra, Madrid, Spain
¹²CIMA (Pamplona)Cancer Center Clinica Universidad de Navarra (CCUN), Centro de Investigacion Medica Aplicada (CIMA), Instituto de Investigacion Sanitaria de Navarra (IdiSNA), CIBER-ONC numbers CB16/12/00369 and CB16/12/00489, Pamplona, Spain
¹³4th Department of Internal Medicine-Hematology, University Hospital Hradec Kralove, Charles University, Faculty of Medicine in Hradec Kralove, Hradec Kralove, Czech Republic
¹⁴Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Voula,Athens, AL, Greece
¹⁵Department of Hematology, Centre for Applied Medical Research, Cancer Center Clinica Universidad de Navarra, University of Navarra, IdiSNA, CIBERONC, Pamplona, Spain
¹⁶University Hospital Ostrava and University of Ostrava, Ostrava, Czech Republic

Sandra Novoa Jáuregui, MD^1*, Maria Gabarros Subira^2*, Ana María Garrido^3*, Laura Palomo, PhD^4*, Irene Medina^5*, Francisco Beas^6*, Marc Bosch, MD^7*, Sofia Muzio, MD^7*, Sergi Camarillas, MD^8*, Gloria Hidalgo-Gomez^9*, Margarita Ortega^10*, Laura Gallur, MD^11*, Carlos Palacio^9*, Adoracion Blanco^12*, Julia Montoro, PhD^3,13*, Silvia Saumell, MD, PhD^14*, Inmaculada Fernández-Camacho, MD^15*, Francesc Bosch, MD, PhD^12,13,16,17, Mercedes Gironella, MD^18* and Andres Jerez, MD, PhD^3,14,19*

¹Hematology Department, Vall d'Hebron University Hospital, University Autònoma of Barcelona (UAB), Barcelona, Spain
²Department of Hematology, Vall d'Hebron University Hospital, Barcelona, Spain / España, Spain
³Vall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain
⁴ICO-Hospital Germans Trias i Pujol, Institut de Recerca contra la Leucèmia Josep Carreras (IJC), Universitat Autònoma de Barcelona, Badalona, ESP
⁵Servei d’Hematologia, Vall d’Hebron Hospital Universitari, Experimental Hematology, Vall d’Hebron Institute of Oncology (VHIO), Vall d’Hebron Barcelona Hospital Campus, Passeig Vall d'Hebron 119-129, 08035 Barcelona, Spain, BARCELONA, Spain
⁶Experimental Hematology Unit, Vall d'Hebron Institute of Oncology (VHIO), Barcelona, AL, Spain
⁷Department of Hematology, Vall d'Hebron University Hospital, Barcelona, Spain
⁸Vall d'Hebron University Hospital, Barcelona, Spain
⁹Experimental Hematology, Vall d'Hebron Institute of Oncology (VHIO), Hospital Universitari Vall d'Hebron, Barcelona, Spain
¹⁰Department of Hematology, University Hospital Vall D´Hebron, Barcelona, BARCELONA, ESP
¹¹Experimental Hematology, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain
¹²Department of Hematology, Vall d’Hebron University Hospital, Barcelona, Spain
¹³Experimental Hematology Unit, Vall d’Hebron Institute of Oncology (VHIO), Vall d'Hebron University Hospital, University Autonoma of Barcelona (UAB), Barcelona, Spain
¹⁴Department of Hematology, Hospital Universitari Vall d'Hebron, Barcelona, Spain
¹⁵Clinical Trials Unit, Vall d'Hebron Institute of Oncology, Barcelona, Spain
¹⁶Hematology Department, Vall d’Hebron Institute of Oncology (VHIO), University Hospital Vall d’Hebron, Barcelona, Spain
¹⁷Department of Hematology, Vall d'Hebron University Hospital, University Autònoma of Barcelona (UAB), Barcelona, Spain
¹⁸Hematology, Hospital Universitari Vall d'Hebron, Barcelona, Spain
¹⁹Experimental Hematology. Hematology Department Vall d´Hebron Institute of Oncology (VHIO), Hospital Universitari Vall d’Hebrón, Barcelona, Spain

Caitlin Unkenholz^1*, Mateo Mejia Saldarriaga, MD², Esther Ortega^3,4*, Jorge Monge, MD⁴, Christian A Gordillo, BS^5*, Juan Esteban Velez-Hernandez, MD^4,6*, Divaya Bhutani, MD⁷, Roger Pearse, MD, PhD^4*, Rajshekhar Chakraborty, MD⁷, Suzanne Lentzsch, MD, PhD⁷, Ran Reshef, MD, MSc⁷, Ruben Niesvizky, MD⁴ and Mark Bustoros, MD⁴

¹Weill Cornell Medicine, New York
²Division of Hematology & Medical Oncology, Weill Cornell Medicine/New York Presbyterian Hospital, NEW YORK, NY
³Hematology Department, Hospital Universitario Jerez de la Frontera, Jerez De La Frontera, Spain
⁴Division of Hematology & Medical Oncology, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY
⁵Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York
⁶Hospital Alma Mater de Antioquia, Medellin, Colombia
⁷Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY

David E. Mery, PhD¹, Yihao Zhan, MD^2,3*, Hongling Peng, MD^4*, Eric Siegel^5*, Cody Ashby, PhD^6*, Clyde Bailey, BS^1*, Catherine Ma^7,8*, Hongwei Xu, DDS^1*, Samer Al Hadidi, MD, MSc⁹, Carolina Schinke, MD¹, Maurizio Zangari, MD¹, Sharmilan Thanendrarajan, MD¹, Frits van Rhee, MD, PhD¹, Guido Tricot, MD^1*, John D Shaughnessy, Jr, PhD^10* and Fenghuang Zhan, MD¹

¹Myeloma Center, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR
²Department of Hematology, Second Xiang-ya Hospital, Central South University, Changsha, China
³University of Arkansas for Medical, Little Rock, AR
⁴Department of Hematology, The Second XIANGYA Hospital, Changsha, China
⁵Department of Biostatistics, University of Arkansas For Medical Sciences, Little Rock, AR
⁶Department of Bioinformatics, University of Arkansas for Medical Sciences, Little Rock, AR
⁷Coppell High School, Coppell, TX
⁸Department of Internal Medicine, University of Arkansas for Medical, Little Rock, AR
⁹University of Arkansas for Medical Sciences, Little Rock, AR
¹⁰Myeloma Center, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical sciences, Little Rock, AR

Carlos Pérez Míguez^1*, Jose Angel Diaz Arias^2*, Davide Crucitti^3,4*, Jesús Gómez Fernández^1*, Manuel Piñeiro Fiel^1*, Marta Sonia Gonzalez Perez^5*, Maria-Victoria Mateos, MD, PhD⁶ and Adrian Mosquera Orgueira, MD, PhD^7,8*

¹Health Research Institute of Santiago de Compostela, Santiago de Compostela, Spain
²University Hospital of Santiago de Compostela, Department of Hematology, IDIS, A Coruña, Spain
³Pharmacology, University of Santiago de Compostela, Santiago de Compostela, Spain
⁴Group of Computational Hematology and Genomics, Health Research Institute of Santiago de Compostela, Santiago de Compostela, Spain
⁵University Hospital of Santiago de Compostela, Santiago de Compostela, Spain
⁶University of Salamanca, Department of Medicine, Salamanca, Spain
⁷University Hospital of Santiago de Compostela, Department of Hematology, IDIS, SANTIAGO DE COMPOSTELA, Spain
⁸Hematology Department, University Hospital of Santiago de Compostela, Group of Computational Hematology and Genomics, IDIS, Santiago de Compostela, Spain

Kohei Sato, MD^1*, Kazuhito Suzuki, MD, PhD², Riku Nagao, MD^3*, Tadahiro Gunji, MD^4*, Masaharu Kawashima, MD, PhD^4*, Hideki Uryu, MD^2*, Mamiko Momoki, MD^2*, Hiroto Ishii, MD, PhD^3*, Mitsuji Katori, MD, PhD^3*, Susumu Tanoue, MD, PhD^2*, Atsushi Katsube, MD^2*, Hiroki Yokoyama, MD, PhD^2*, Takeshi Saito, MD, PhD², Kaichi Nishiwaki, MD, PhD^3* and Shingo Yano, MD, PhD²

¹Division of Clinical Oncology/Hematology, The Jikei University Hospital, Minato, TKY, Japan
²Division of Clinical Oncology/Hematology, The Jikei University Hospital, Tokyo, Japan
³Division of Clinical Oncology/Hematology, The Jikei University Kashiwa Hospital, Chiba, Japan
⁴Division of Clinical Oncology/Hematology, The Jikei University Daisan Hospital, Tokyo, Japan

Dan Guo^1*, Wenfeng Su^1*, Jinfeng Lu^1*, Lemin Hong^1*, Bingzong Li, MD, PhD² and Huang Hongming^3*

¹Affiliated Hospital of Nantong University, Nantong, China
²Jiangsu Cooperative Lymphoma Group (JCLG)., Nanjing, China
³Affiliated Hospital of Nantong University, Hematology, Natong, China, Natong, China

Myo Htut, MD¹, Keehoon Lee, Research Assistant Professor^2*, Nitya Nathwani, MD¹, Michael Rosenzweig, MD¹, Murali Janakiram, MBBS¹, Scott R. Goldsmith, MD¹, James F. Sanchez, PhD^3*, Martha Scott^4*, Jonathan Keats^1,5*, Amrita Y Krishnan, MD, FACP⁶, Steven T. Rosen, MD^7,8,9 and Sophia S. Wang, PhD^10*

¹Judy and Bernard Briskin Center for Multiple Myeloma Research, City of Hope, Duarte, CA
²Translational Genomics Research Institute (TGen North), part of City of Hope, Flagstaff, AZ
³Clinical and Translational Project Development, City of Hope National Medical Center, Duarte, CA
⁴BRC 2084.02, City of Hope Medical Center, Duarte, CA
⁵Translational Genomics Research Institute, Phoenix, CA
⁶Judy and Bernard Briskin Center for Multiple Myeloma Research, City of Hope, Irvine, CA
⁷Department of Hematology and HCT, City of Hope Comprehensive Cancer Center, Duarte, CA
⁸City of Hope Comprehensive Cancer Center, Toni Stephenson Lymphoma Center, Beckman Research Institute, Duarte, CA
⁹Department of Hematology and Hematopoietic Cell Transplantation, Beckman Research Institute, City of Hope, Duarte, CA
¹⁰City of Hope Comprehensive Cancer Center, Duarte, CA

Emmanuel Bugarin-Estrada^1*, Jorge Monge, MD², Roger Pearse, MD, PhD^2*, Ruben Niesvizky, MD² and Mateo Mejia Saldarriaga, MD³

¹Internal Medicine, University of Miami Health System, Miami, FL
²Division of Hematology & Medical Oncology, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY
³Division of Hematology & Medical Oncology, Weill Cornell Medicine/New York Presbyterian Hospital, NEW YORK, NY

Martha Romero Prieto, MD^1*, Andrés Melo Arias^2*, Juan Guio Oros^3*, Natalia Tijaro Ovalle⁴, Gonzalo Ucros^5*, Karen Galvis^6*, Diana Martinez^7*, Gina Cuellar^6*, Carlos Saavedra^7*, Liliana Martin^6*, Sandra Quijano^8*, Andres Borda Molina, MD^9*, Guillermo Quintero^10*, Mónica Duarte^11*, Juanita Zuluaga Castro^12*, Julian Cubillo^13*, Viviana Barrera^13*, Claudia Agudelo, MD^9*, Carmenza Camargo, MD^9*, Beatriz Wills, MD¹⁴, Luis Buitrago, MD^9*, Marco Paez^15*, Oscar Torres^16*, Oscar Rivero^17*, Joaquin Martínez-López^18* and Patricia Bernal^19*

¹Department of Pathology and Laboratory, Fundacion Santa Fe de Bogota Hospital, Bogota, Colombia
²San Carlos Hospital, Madrid, Spain
³Center of Excellence for Multiple Myeloma, Fundacion Santa Fe de Bogota Hospital, Bogota, Colombia
⁴Memorial Sloan Kettering Cancer Center, Nueva York
⁵Nuclear Medicine, Fundacion Santa Fe de Bogota Hospital, Bogota, Colombia
⁶Department of Pathology and Laboratory,, Fundacion Santa Fe de Bogota Hospital, Bogota, Colombia
⁷Department of Pathology and Laboratory,, Fundacion Santa Fe de Bogota Hospital, Bogotá, Colombia
⁸Department of Pathology and Laboratory,, Fundacion Santa Fe de Bogota, Bogota, Colombia
⁹Department of Hematology, Fundación Santa Fe de Bogotá, Bogotá, Colombia
¹⁰Department of Hematology, Fundacion Santa Fe de Bogota Hospital, Bogota, COL
¹¹Department of Hematology, Fundacion Santa Fe de Bogota Hospital, Bogotá, COL
¹²Center of Excellence for Multiple Myeloma, Fundacion Santa Fe de Bogota, Bogota, Colombia
¹³Department of Pathology and Laboratory, Fundacion Santa Fe de Bogota Hospital, Bogotá, Colombia
¹⁴Lymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁵Department of Pathology and Laboratory, Fundacion Santa Fe de Bogota, Bogota, Colombia
¹⁶Department of Radiology, Bogota, Colombia
¹⁷Department of Radiology, Fundacion Santa Fe de Bogota, Bogota, Colombia
¹⁸Department of Hematology, Hospital Universitario 12 de Octubre, Madrid, Spain
¹⁹Nuclear medicine, Fundacion Santa Fe de Bogota, Bogota, Colombia

Noriko Nishimura, MD^1,2,3, Sham Mailankody, MD, MBBS², Samantha Brown^4*, Sean M. Devlin, PhD^4*, Bruno Almeida Costa, MD⁵, Tasmin Farzana, MPH^2*, Eric M Jurgens, MD², Ross S Firestone, MD, PhD², Karthik Nath^6*, David J. Chung, MD, PhD⁷, Heather J. Landau, MD⁸, Michael Scordo, MD⁹, Gunjan L. Shah, MD⁸, Roni Shouval, MD, PhD¹⁰, Hamza Sloan Hashmi, MD^2*, Hani Hassoun, MD², Kylee H Maclachlan, PhD, BSc, FRACP, FRCPA², Malin Hultcrantz, MD, PhD², Neha Korde, MD², Alexander M. Lesokhin, MD¹¹, Urvi A. Shah, MD², Carlyn Rose Tan, MD², Sergio A. Giralt, MD¹², Saad Z. Usmani, MD² and Sridevi Rajeeve, MD^13*

¹Department of Hematology/Oncology, The Cancer Institute Hospital, Tokyo, NY, Japan
²Myeloma Service, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
³Division of Hematologic Malignancies, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁴Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
⁵The Mount Sinai Hospital, Brookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine at Mount Sinai, NEW YORK, NY
⁶Icon Cancer Centr, South Brisbane, AUS
⁷Transplant and Cellular Therapy Services, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁸Adult Bone Marrow Transplant Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁹Transplant and Cellular Therapy Services, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York City, NY
¹⁰Adult Bone Marrow Transplantation Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
¹¹Myeloma & Cell Therapy Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
¹²Adult Bone Marrow Transplantation Service, Memorial Sloan Kettering Cancer Center, New York, NY
¹³Myeloma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY

Arwa Bohra, MBBS^1*, Surendra Dasari, PhD^2*, Wilson I. Gonsalves, MD³, Prashant Kapoor, MD⁴, Saurabh Zanwar, MD^1*, Moritz Binder, MD¹, Angela Dispenzieri, MD¹, Michael M Timm^5*, Dragan Jevremovic, M.D., Ph.D^5*, S. Vincent Rajkumar, MD^1* and Shaji Kumar, MD¹

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN
³Division of Hematology, Mayo School of Graduate Medical Education, Rochester, MN
⁴Mayo Clinic, Rochester, MN
⁵Division of Hematopathology, Mayo Clinic, Rochester, MN

Maher Albitar, MD¹, Hong Zhang, MD^1*, Sally Agersborg, MD, PhD^1*, Ahmad Charifa, MD^1*, Pooja Phull, MD^2*, Noa Biran, MD², David H. Vesole, MD, PhD³, Harsh Parmar, MD², Andrew L Pecora, MD⁴, Andrew Ip, MD, MSc⁵, Andre Goy, MD, MS³ and David S. Siegel, MD, PhD⁴

¹Genomic Testing Cooperative, Lake Forest, CA
²Division of Multiple Myeloma, John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ
³John Theurer Cancer Center, Hackensack, NJ
⁴Hackensack University Medical Center, Hackensack, NJ
⁵Lymphoma Division, John Theurer Cancer Center, Hackensack Meridian Health, Hackensack, NJ

Arghya Ray, PhD¹, Yan Song, PhD^1*, Ting Du, PhD^1*, Leutz Buon, MS^2*, Md. Abu Musa, PhD^1*, Xueping Wan, PhD^1*, Sindhu C Pillai, PhD^1*, Teng Fang, PhD^1*, Minxing Wang, MS^1*, Dharminder Chauhan, PhD^1* and Kenneth C. Anderson, MD³

¹The Jerome Lipper Multiple Myeloma Center,Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
²Dana Farber Cancer Institute, Harvard Medical School, Boston, MA
³Dana-Farber Cancer Institute, The Jerome Lipper Multiple Myeloma Center, Boston, MA

Meletios-Athanasios Dimopoulos¹, Despina Fotiou, MD^1*, Foteini Theodorakakou, MD^1*, Irene Solia, MD^1*, Vasiliki Spiliopoulou, MD^1*, Ioannis Ntanasis-Stathopoulos, MD, PhD, MSc^1*, Panagiotis Malandrakis, MD^1*, Erasmia Psimenou, MD^1*, Nikolaos Kanellias^1*, Maria Roussou, MD^1*, Magdalini Migkou, MD^1*, Evangelos Eleutherakis-Papaiakovou, MD^1*, Maria Gavriatopoulou^1*, Evangelos Terpos, MD, PhD² and Efstathios Kastritis, MD^3*

¹Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
²Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Drosia, Attiki, Greece
³Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Voula,Athens, AL, Greece

Benjamin A Derman, MD¹, Tadeusz Kubicki^2*, Jennifer H Cooperrider, MD¹, Anna Pula^2*, Ken Jiang^2*, Mariel Coradin^3*, Ravleen Virdi, MSc^3*, Fionn McLoughlin, PhD^3*, Luciano Di Stefano, PhD^4*, Vincent Bonifay, PhD^5*, Caroline Rougé Dubroc, PharmD^4* and Andrzej J Jakubowiak, MD, PhD¹

¹Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL
²University of Chicago, Chicago, IL
³Corgenix Clinical Laboratory, Broomfield, CO
⁴Sebia, Lisses, France
⁵SEBIA, Lisses, France

Sanjay De Mel, BSc, FRCPath, MRCP^1*, Jonathan Scolnick, PhD^2*, Chern Han Yong, PhD^3*, Stacy Li Wen Xu, PhD^4*, Xiaojing Huo^4*, Cinnie Soekojo, MRCP (UK), FRCPath^5*, Fang Fang Song^6*, Melissa G Ooi, MB BCh, BAO, MRCP(I), FRCPath, PhD^7,8,9*, Phyu The, BSc^10*, Radhika Sharma^11*, Yanfen Peng^12*, Sabrina Toh^13*, Siok-Bian Ng^14*, Anand Devaprasath Jeyasekharan, MBBS, MRCP, PhD^15*, Joe Yeong, FRCPath, PhD^16*, Li Yen Chong^17*, Chi Ching Lim, MN, APN^18*, Felicia Wee^17*, Jinmiao Chen, PhD^17*, Lim Soon Wong, PhD^3*, Jun Siong Low, PhD^19* and Wee-Joo Chng, FRCP, FRCPath, PhD²⁰

¹Department of Haematology-Oncology, National University Cancer Institute, Singapore, National University Health System, Singapore, Singapore
²Singleron Biothechnologies Pte Ltd, Singapore, Singapore
³School of Computing, National University of Singapore, Singapore, Singapore
⁴Singleron Biotechnologies Pte Ltd, Singapore., Singapore, Singapore
⁵National University Cancer Institute, Singapore, National University Health Syst, Singapore, MD, SGP
⁶Haematology Oncology, National University Cancer Institute Singapore, Singapore, Singapore
⁷National University Cancer Institute, Singapore, Singapore
⁸National University Cancer Institute Singapore, National University Health System, Singapore, Singapore
⁹Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore
¹⁰Pathology, National University of Singapore, Singapore, Singapore
¹¹Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore
¹²National University of Singapore, Singapore, SGP
¹³Cancer Science Institute of Singapore, Singapore, SGP
¹⁴Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
¹⁵Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore, Singapore
¹⁶Institute of Molecular Cell Biology, Agency for Science, Technology and Research, Singapore, SGP
¹⁷Institute of Molecular Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore
¹⁸National University Cancer Institute, Singapore, National University Hospital, Singapore, Singapore
¹⁹Cancer Science Institute of Singapore, National University of Singapore, singapore, Singapore
²⁰National University Cancer Institute of Singapore, Singapore, Singapore

Kenneth J C Lim, MBBS^1,2,3, Cameron Wellard, BSc (Hons), PhD^4*, Elizabeth Moore, PhD, MPH, PgradDip (Nurs Crit Care)^4*, Betty Gration, BMBCh^5*, Bradley Augustson, MBBS, FRACP, FRCPA^6*, Peter Mollee, FRACP, MBBS, MSc, FRCPA^7,8, Jennifer Zhang, PhD^9*, Nicole Wong Doo, MBBS, MD, FRACP, FRCPA^10,11, Sabine Ringkowski, MD¹², Adam Bryant, MBBS(Hon), PhD, FRACP, FRCPA^12,13*, Slavisa Ninkovic, MBBS^14,15,16, Nada Hamad, MBBS, MSc, BSc^17,18,19, Georgia McCaughan, MBBS, MMed^20,21*, Shaji Kumar, MD²², Andrew Spencer, MBBS^23,24* and Hang Quach, MD, FRACP, FRCPA, MBBS^25,26

¹Hematology, St Vincent's Hospital Melbourne, Brunswick, Australia
²Division of Hematology,, Mayo Clinic Rochester, Rochester, MN
³Victorian Cancer Cytogenetic Service, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia
⁴School of Public Health and Preventative Medicine, Monash University, Melbourne, VIC, Australia
⁵Haematology, St Vincent's Hospital Sydney, Sydney, Australia
⁶Sir Charles Gairdner Hospital and Linear Clinical Research, Perth, Western Australia, Australia
⁷Faculty of Medicine, University of Queensland, Brisbane, QLD, Australia
⁸Department of Haematology, Princess Alexandra Hospital, Brisbane, QLD, Australia
⁹Concord Repatriation General Hospital, Sydney, Australia
¹⁰Department of Haematology, Concord Hospital, University of Sydney, Concord, NSW, AUS
¹¹Concord Clinical School, Faculty of Medicine and Health, University of Sydney, Australia, Concord, NSW, Australia
¹²Hematology, Liverpool Hospital, Liverpool, NSW, AUS
¹³Liverpool Hospital, Sydney, Australia
¹⁴Faculty of Medicine, University of Melbourne, Melbourne, Australia
¹⁵Haematology, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia
¹⁶Victorian Cancer Cytogenetics Service, St Vincent's Hospital Melbourne, Fitzroy, VIC, Australia
¹⁷Haematology Department, The Kinghorn Cancer Centre, St Vincent's Hospital, Darlinghurst, NSW, Australia
¹⁸School of Clinical Medicine, Faculty of Medicine and Health, The University of New South Wales, Sydney, NSW, Australia
¹⁹School of Medicine, University of Notre Dame, Sydney, Australia
²⁰School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales, Sydney, NSW, Australia
²¹Department of Haematology, St. Vincent's Hospital, Sydney, Australia
²²Division of Hematology, Mayo Clinic, Rochester, MN
²³Department of Malignant Haematology & Stem Cell Transplantation, The Alfred Hospital, Melbourne, Australia
²⁴School of Translational Medicine, Alfred Health-Monash University, Melbourne, VIC, Australia
²⁵Department of Haematology, St Vincent’s Hospital Melbourne, Victoria, Australia, Melbourne, VIC, Australia
²⁶University of Melbourne, St. Vincent’s Hospital, Melbourne, VIC, Australia

Jan H. Frenking, MD^1,2*, Christine Riedhammer, MD^3*, David N. Sedloev, MD^4*, Valentine Landrin^1*, Mirco Julian Friedrich, MD, PhD^5,6*, Niels Weinhold, PhD^5*, Martin K. Kortüm^7*, Carsten Müller-Tidow, MD^8,9*, Hermann Einsele, MD¹⁰, Sandra Sauer, MD^11*, Leo Rasche, MD^12* and Marc S. Raab^5,13*

¹Heidelberg Myeloma Center, Department of Medicine V, Heidelberg University Hospital, Heidelberg, Germany
²Clinical Cooperation Unit Molecular Hematology/Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany
³University Hospital Wuerzburg, Wuerzburg, Germany
⁴Heidelberg Myeloma Center, Department of Medicine V, Heidelberg University Hospital, Heidelberg, AL, Germany
⁵Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Heidelberg, Germany
⁶Broad Institute of MIT and Harvard, Cambridge, MA
⁷Department of Medicine II, University Hospital of Wuerzburg, Wuerzburg, Germany
⁸Department of Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany
⁹National Center for Tumor Diseases Heidelberg, Heidelberg, Germany
¹⁰Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany
¹¹Heidelberg Myeloma Center, Internal Medicine V, Hematology, Oncology and Rheumatology, Heidelberg University Hospital, Heidelberg, Germany
¹²Department of Internal Medicine, University Hospital of Würzburg, Würzburg, Germany
¹³German Cancer Research Center, Heidelberg, Germany

David Murray, MD, PhD^1*, Mindy Kohlhagen, BS^1*, Jon Coker, PhD^2*, Maria Alice V. Willrich, PhD, MSc^3*, Surendra Dasari, PhD^4* and Angela Dispenzieri, MD⁵

¹Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
²Xylo Technologies, Mayo Clinic, Rochester, MN
³Department of Laboratory Medicine, Mayo Clinic, Rochester, MN
⁴Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN
⁵Division of Hematology, Mayo Clinic, Rochester, MN

Sahar Khan, FRCPath, MB BCh^1*, Salman Basrai^2,3*, Esther Masih-Khan, PhD^4*, Harjot Vohra, MD, CCRP, MLT^4*, Donna Reece, MD⁴, Suzanne Trudel, MD, MSc⁴, Keith Stewart, MB BCh, MBA^4*, Sita D. Bhella, MD⁴, Vishal Kukreti, MD, MSc⁵, Chloe Yang, MD^4*, Rodger E Tiedemann, MBChB, PhD⁴, Anca Prica, MD⁶, Aaron Schimmer^7*, Sagi Abelson^3,8* and Christine I Chen, MHPE, MD⁹

¹Windsor Regional Cancer Centre, Windsor, ON, Canada
²Ontario Institute for Cancer Research, Mississauga, ON, Canada
³Ontario Institute for Cancer Research, Toronto, Canada
⁴Princess Margaret Cancer Centre, Toronto, ON, Canada
⁵Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON, Canada
⁶Divison of Medical Oncology and Hematology, Princess Margaret Cancer Centre - University Health Network, Toronto, ON, Canada
⁷Princess Margaret Cancer Centre / University Health Network, Toronto, ON, Canada
⁸University Health Network, Princess Margaret Cancer Centre, Toronto, Canada
⁹Princess Margaret Cancer Centre - University Health Network, Toronto, ON, Canada

Elham Askari^1*, Angela Dispenzieri, MD¹, Francis K. Baudi, MD^1*, Suzanne R Hayman, MD¹, Morie A. Gertz, MD¹, Prashant Kapoor, MD², Wilson I. Gonsalves, MD¹, Taxiarchis Kourelis, MD¹, David Dingli, MD, PhD¹, Rahma M Warsame, MD¹, Nelson Leung, MD¹, Yi Lin, MD, PhD¹, Eli Muchtar, MD¹, Joselle Cook, MBBS¹, Moritz Binder, MD¹, Nadine Abdallah, MD², Yi Lisa Hwa, APRN, DNP, CNP¹, Michelle G. Rogers, CNP^1*, Miriam Hobbs, APRN, CNP, DNP^1*, Amie Fonder, PA-C, MS^1*, David Murray, MD, PhD^3*, Robert A. Kyle, MD¹, Vincent Rajkumar, MD^1* and Shaji Kumar, MD¹

¹Division of Hematology, Mayo Clinic, Rochester, MN
²Mayo Clinic, Rochester, MN
³Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN

Rintu Sharma, MBBS MD DM¹, Pamella Paul^2*, Esther Masih-Khan^2*, Eshetu G. Atenafu^3*, Harjot Vohra, MD, CCRP, MLT^4*, Sita D. Bhella, MD⁵, Christine I Chen, MHPE, MD⁶, Vishal Kukreti, MD, MSc⁷, Guido Lancman, MD, MSc⁴, Donna E Reece, MD⁸, A. Keith Stewart, MBChB⁹, Rodger E Tiedemann, MBChB, PhD¹⁰, Chloe Yang, MD^5* and Suzanne Trudel, MD, MSc¹¹

¹Division of Medical Oncology and Hematology, Princess Margaret Cancer Center - University Health Network, Toronto, ON, Canada
²Princess Margaret Cancer Center- University Health Network, Toronto, ON, Canada
³Biostatistics Department, Princess Margaret Cancer Center, Toronto, ON, Canada
⁴Princess Margaret Cancer Centre, Toronto, ON, Canada
⁵Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre - University Health Network, Toronto, ON, Canada
⁶Princess Margaret Cancer Centre - University Health Network, Toronto, ON, Canada
⁷Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON, Canada
⁸Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre- University Health Network, Toronto, ON, Canada
⁹Division of Medical Oncology and Hematology, University of Toronto/Princess Margaret Cancer Center- University Health Network, Toronto, ON, Canada
¹⁰School of Medical Sciences, Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand
¹¹Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre - University Health Network, Toronto, ON, Canada

Rafael Alonso Fernandez, MD^1*, Andrés Arroyo Barea^2*, Maria Teresa Cedena Romero, MD, PhD^3*, Laura Rosiñol Dachs^4*, Javier de la Rubia^5*, Sara Miqueleiz, MD^6*, Veronica Gonzalez-Calle, MD, PhD^7*, Felipe De Arriba, MD, PhD^8*, Luis Felipe Casado Montero, MD⁹, Miguel Teodoro Hernandez, MD^10*, Maria Mas Esteve, MD^11*, Pascual Fernandez^12*, Paula Rodríguez-Otero, MD, PhD^13*, Carmen Calle Primo^14*, Eugenia Abella, PhD^15*, Paz Ribas^16*, Adrian Alegre, MD^17*, Juan Miguel Bergua, MD^18*, Irene Gomez-Catalan^19*, Jose Maria Arguiñano Perez^20*, Luis Palomera, MD, PhD^21*, Enrique M Ocio, MD, PhD^22*, Maria Jose Busto Medina^23*, Nieves Somolinos^24*, Jose Maria Alonso Alonso^25*, Aránzazu García Mateo, PhD^26*, Joan Bargay^27*, Pilar Delgado, MD, PhD^28*, Dunia De Miguel Llorente^29*, Javier de la Cruz^30*, Maria Victoria Mateos, MD, PhD³¹, Jesús F. San-Miguel, MD, PhD³², Joan Bladé, MD, PhD^33*, Juan-Jose Lahuerta Palacios, MD, PhD^34* and Joaquin Martinez Lopez, PhD, MD^35*

¹Department of Hematology, Hospital Universitario 12 de Octubre, Spanish National Cancer Research Center (CNIO), Complutense University Madrid, Madrid, Spain
²Hospital Universitario 12 De Octubre, Imas12 Madrid, Madrid, ESP
³Hematology Department, Hospital Universitario 12 de Octubre, CIBER-ONC, Instituto de Investigación IMAS12, Madrid, Spain
⁴Hematology Department, Hospital Clinic de Barcelona and Insitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
⁵Hematology Department, Hospital Universitari i Politècnic La Fe, Valencia, Spain
⁶Department of Hematology, Hospital de la Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, Spain, Barcelona, Spain
⁷Hospital Universitario de Salamanca, Instituto de Investigacion Biomedica de Salamanca (IBSAL), University of Salamanca, Salamanca, Spain
⁸Hospital Morales Meseguer, IMIB-Arrixaca, Universidad de Murcia, Murcia, Spain
⁹Hospital General Universitario de Toledo, Toledo, Spain
¹⁰Department of Hematology, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain
¹¹Department of Hematology, Hospital General de Castellón, Castellón, Spain
¹²Hospital General de Alicante, ALICANTE, Spain
¹³Department of Hematology, Cancer Center Clínica Universidad de Navarra, Pamplona, Navarra, Spain
¹⁴Department of Hematology, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain
¹⁵Department of Hematology, Hospital del Mar, Barcelona, Spain
¹⁶Hospital Universitario Dr Peset Aleixandre, Valencia, Spain
¹⁷Department of Hematology, Hospital Universitario de La Princesa, Madrid, Spain
¹⁸Department of Hematology, Hospital San Pedro de Alcántara, Cáceres, Spain
¹⁹Department of Hematology, Complejo Hospitalario Universitario de Albacete, Albacete, Spain
²⁰Department of Hematology, Hospital Universitario de Navarra, IdiSNA, Pamplona, Spain
²¹Hospital Clinico Universitario Lozano Blesa, Instituto Investigacion Sanitaria Aragon, Zaragoza, Spain
²²Hospital Universitario Marqués de Valdecilla (IDIVAL), Universidad de Cantabria, Santander, Spain
²³Department of Hematology, Hospital Virgen de la Luz, Cuenca, Spain
²⁴Department of Hematology, Hospital Universitario de Getafe, Getafe, Spain
²⁵Hematology Department, Hospital Rio Carrión, Palencia, Spain
²⁶Department of Hematology, Hospital General de Segovia, Segovia, Spain
²⁷Hematology Department, Hospital Universitario Son Llàtzer. IdIsBa., Palma de Mallorca, Spain
²⁸Hematology Department, Hospital Universitario Miguel Servet, Zaragoza, Spain
²⁹Hospital Universitario de Guadalajara, Guadalajara, Spain, Guadalajara, Spain
³⁰Research Institute imas12, Hospital Universitario 12 de Octubre, Madrid, Spain
³¹Hospital Universitario de Salamanca/IBSAL/CIC/Ciberonc, Salamanca, Spain
³²Department of Hematology, Centre for Applied Medical Research, Cancer Center Clinica Universidad de Navarra, University of Navarra, IdiSNA, CIBERONC, Pamplona, Spain
³³Hematology, Hospital Clínic de Barcelona, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), University of Barcelona; and GEM/PETHEMA, Barcelona, Spain
³⁴Research Institute of the Hospital Universitario 12 de Octubre and Board of the Spanish Myeloma Group (PETHEMA/GEM), Madrid, Spain
³⁵Hematology Department, Hospital Universitario 12 de Octubre, Madrid, Spain

Daniel K Reef, MD¹, Jorge A Florindez, MD², Sascha Tuchman, MD³, Eben I Lichtman, MD⁴ and Samuel M. Rubinstein, MD^3,5

¹Department of Medicine, Division of Oncology, University of North Carolina-Chapel Hill, Chapel Hill, NC
²Johns Hopkins University Cancer Center, Baltimore, MD
³Division of Hematology, University of North Carolina School of Medicine, Chapel Hill, NC
⁴Division of Hematology, University of North Carolina School of Medicine, Durham, MA
⁵Lineberger Comprehensive Cancer Center, Chapel Hill, NC

Michael Sheu, MD^1*, Ali Mushtaq, MD^2*, Sofia Molina Garcia, MD^3*, Faiz Anwer, MD⁴, Meera Patel, MD^2*, Thomas Andrew Crilley, MD^5*, Muhammad Anns Asif^6* and Aneela Majeed, MD^5*

¹Department of Internal Medicine, Cleveland Clinic, Cleveland, OH
²Internal Medicine, Cleveland Clinic, Cleveland, OH
³Infectious Disease, Mayo Clinic, Rochester, MN
⁴Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH
⁵Infectious Disease, Cleveland Clinic, Cleveland, OH
⁶Health Sciences, University of Toronto, Toronto, Canada

Charles Agbuduwe, MBBS, PhD, FRCPath¹, Dinh Van Chi Mai^2,3*, Nikita Balaji^4,5*, Amrutha Sridhar^6*, Kathleen Cheok, MBBS⁶, Marzia Rahman, MBBS^6*, Conor Feely^6*, Hanna Renshaw, MD, BA^6*, Simon Wan^4,5*, Charalampia Kyriakou, MD, PhD⁷, John T Jenkins^2,3* and Rakesh Popat^6,7

¹NIHR UCLH Clinical Research Facility, University College London Hospitals NHS Foundation Trust, London, ENG, United Kingdom
²The BiCyCLE Research Group, St Mark’s Academic Institute and the National Bowel Hospital, London, United Kingdom
³Department of Surgery and Cancer, Imperial College, London, London, United Kingdom
⁴The Institute of Nuclear Medicine, University College London Hospitals NHS Foundation Trust, London, United Kingdom
⁵The Institute of Nuclear Medicine, University College London, London, United Kingdom
⁶NIHR UCLH Clinical Research Facility, University College London Hospitals NHS Foundation Trust, London, United Kingdom
⁷Department of Haematology, University College London Hospitals NHS Foundation Trust, London, United Kingdom

Jialin Zhou^1,2*, Hanheng Mai^2,3*, Yunqing Liu^4,5*, Na Wang^6*, Xiao Lv^6*, Xin Wang, MD, PhD⁶ and Lili Feng, MD, PhD^5*

¹Shandong University Cancer Center, Jinan, China
²Department of Radiation Oncology and Shandong Provincial Key Laboratory of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China
³The First Affiliated Hospital of Shantou University Medical College, Shantou, China
⁴Shandong Second Medical University, Weifang, China
⁵Department of Hematology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan, China
⁶Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China

Ondrej Venglar^1,2*, Eva Radova^1,2*, David Zihala^1,3*, Ivana Tvrda^1*, Ludmila Muronova^3,4*, Veronika Kapustova^1,2*, Lucie Broskevicova^1,2*, Jan Vrana^1*, Tereza Popkova, MD^3,4*, Jana Mihalyova^1,2*, Hana Plonkova, MD^4*, Tereza Sevcikova^1,2*, Michal Kascak^1,2*, Milan Navratil^1,2*, Zdenek Koristek^1,5*, Roman Hajek, MD, PhD^2,6 and Tomas Jelinek^1,2

¹Department of Hematooncology, University Hospital Ostrava, Ostrava, Czech Republic
²Department of Hematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
³Department of Haematooncology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
⁴Department of Haematooncology, University Hospital Ostrava, Ostrava, Czech Republic
⁵Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic
⁶University Hospital Ostrava and University of Ostrava, Ostrava, Czech Republic

Anna Fleischer^1*, Elias K. Mai, MD^2,3*, Kaya Miah^4,5*, Uta Bertsch, MD^6*, Britta Besemer, MD^7*, Mathias Hänel, MD⁸, Roland Fenk, MD, PhD^9*, Markus Munder^10*, Christine Hanoun^11*, Igor Wolfgang Blau, MD, PhD^12*, Christoph Mann, MD^13*, Christof Scheid, MD¹⁴, Roland Schroers, MD^15*, Ivana von Metzler, MD^16*, Aneta Schieferdecker^17*, Jörg Thomalla, MD^18*, Peter Reimer, MD^19,20*, Rolf Mahlberg, MD^21*, Ullrich Graeven, MD^22*, Stephan Kremers^23*, Uwe Martens, MD^24*, Christian Kunz^25*, Manfred Hensel, MD^26*, Marc S. Raab^27*, Katja C. Weisel, MD^28,29, Hans Salwender, MD^30*, Imad Maatouk, MD^1* and Hartmut Goldschmidt, MD^31,32

¹Department of Internal Medicine II, University Hospital Wuerzburg, Wuerzburg, Germany
²Medicine V, University Hospital Heidelberg, Heidelberg, Germany
³Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Heidelberg, Germany
⁴3. Division of Biostatistics, German Cancer Research Center Heidelberg, Heidelberg, Germany., Heidelberg, Germany
⁵German Cancer Research Center (DKFZ), Heidelberg, DEU
⁶Department of Medicine V, Heidelberg Myeloma Center, University Hospital Heidelberg, Heidelberg, Germany
⁷Department of Internal Medicine II, University Hospital Tübingen, Tübingen, Germany
⁸Department of Internal Medicine III, Klinikum Chemnitz, Chemnitz, Germany
⁹Department of Haematology, Oncology, and Clinical Immunology, University Hospital Düsseldorf, Düsseldorf, Germany
¹⁰Third Department of Medicine, University Medical Center of the Johannes Gutenberg University, Mainz, Germany
¹¹Uniklinikum Essen, Essen, DEU
¹²Medizinische Klinik m. S. Hämatologie, Onkologie und Tumorimmunologie, Berlin, Germany
¹³Department of Haematology, Oncology and Immunology, Philipps-University Marburg, Marburg, Germany
¹⁴Department of Internal Medicine I, University Hospital Cologne, Cologne, Germany
¹⁵Medical Clinic, University Hospital Bochum, Bochum, Germany
¹⁶Department of Internal Medicine II, University Hospital Frankfurt a.M., Frankfurt a.M., Germany, Frankfurt am Main, Germany
¹⁷Department of Oncology, Hematology and Bone Marrow Transplantation with Section of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
¹⁸Hematology / Oncology Center, Koblenz, Germany
¹⁹Evang. Kliniken Essen-Mitte, Evang. Krankenhaus Essen-Werden, Essen, Germany, Essen, Germany
²⁰Evang. Kliniken Essen-Mitte, Evang. Krankenhaus Essen-Werden, Essen, Germany
²¹Internal Medicine I, Hospital Mutterhaus der Borromäerinnen, Trier, Germany
²²Medical Clinic I, Hospital Maria Hilf GmbH, Mönchengladbach, Germany
²³Hematology / Oncology Center, Lebach, Germany
²⁴Hematology, Oncology, Palliative Care, SLK Clinic Heilbronn, Heilbronn, Germany
²⁵Hematology and Oncology, Westpfalz-Klinikum, Kaiserslautern, Germany
²⁶Mannheimer Onkologie Praxis, Mannheim, Germany
²⁷German Cancer Research Center, Heidelberg, Germany
²⁸Universitatsklinikum Tubingen, Hamburg, Germany
²⁹University Medical Center of Hamburg-Eppendorf, Hamburg, Germany
³⁰Asklepios Tumorzentrum Hamburg, Asklepios Hospital Hamburg Altona, Hamburg, Germany
³¹Internal Medicine V, Hematology, Oncology and Rheumatology, GMMG Studygroup, Heidelberg University Hospital, Heidelberg, Germany
³²Department of Medicine V, Heidelberg Myeloma Centre, University Hospital Heidelberg, Heidelberg, Germany; National Centre for Tumour Diseases Heidelberg, Heidelberg, Germany. Electronic address: hartmut.goldschmidt@med.uni-heidelberg.de., Heidelberg, Germany

David M Foureau¹, Oscar Berlanga, PhD^2*, Cindy Varga, MD, BSc³, Barry Paul, MD, MS⁴, Shebli Atrash, MD⁵, Christopher Ferreri⁴, Semegne Hiruy, BS^6*, Lawrence J. Druhan, PhD⁷, Ariel Bell, MPH^7*, Phillip Holmes-Snowden, MHA^7*, Gabriella Lakos², Peter M. Voorhees, MD⁸ and Manisha Bhutani, MD⁹

¹Levine Cancer Institute, Atrium Health, Charlotte, NC
²The Binding Site, Birmingham, United Kingdom
³Department of Hematologic Oncology and Blood Disorders, Levine Cancer Institute, Atrium Health, Charlotte, NC
⁴Levine Cancer Institute, Atrium Health Wake Forest University School of Medicine, Charlotte, NC
⁵Department of Hematologic Oncology & Blood Disorders, Levine Cancer Institute, Atrium Health Wake Forest University School of Medicine, Charlotte, NC
⁶Wake Forest School of Medicine, Winston Salem
⁷Hematology Oncology Translational Research Laboratory, Atrium Health Levine Cancer Institute, Charlotte, NC
⁸Plasma Cell Disorders Section, Department of Hematologic Oncology & Blood Disorders, Levine Cancer Center, Charlotte, NC
⁹Department of Hematologic Oncology and Blood Disorders, Atrium Health Levine Cancer Institute, Charlotte, NC

Razan Mansour, MD^1,2*, Kimberly M Green, DO^2,3*, Mark Chang, DO^2,4*, Gray Magee, MD^2,5, James A Davis, PharmD^2,3*, Shebli Atrash^2,6*, Nausheen Ahmed, MD^2,7, Muhammad Umair Mushtaq^2,8, Evguenia Ouchveridze, MD^2,9, Zahra Mahmoudjafari, PharmD^2,8*, Al-Ola Abdallah, MD^2,8, Barry Paul, MD, MS^2,10, Nicole Twardowski, DO¹¹ and Hamza Sloan Hashmi, MD^2,12*

¹Internal Medicine, The University of Kansas Medical Center, Kansas City, KS
²US Myeloma Innovations Research Collaborative (USMIRC), Kansas City, KS
³Division of Hematology-Oncology, Medical University of South Carolina, Charleston, SC
⁴Levine Cancer, Atrium Health, Charlotte, NC
⁵Levine Cancer Institute, Atrium Health, Charlotte, NC
⁶Levine Cancer, Atrium Health, Wake Forest University School of Medicine, Charlotte, NC
⁷University of Kansas Cancer Center, Kansas City, KS
⁸Division of Hematologic Malignancies & Cellular Therapeutics, University of Kansas Medical Center, Kansas City, KS
⁹Division of Hematologic Malignancies & Cellular Therapeutics, University of Kansas Medical Center, Westwood, KS
¹⁰Levine Cancer Institute, Atrium Health Wake Forest University School of Medicine, Charlotte, NC
¹¹Division of Hematologic Malignancies and Cellular Therapeutics, The University of Kansas Cancer Center, Westwood, KS
¹²Department of Hematology-Oncology, Medical University of South Carolina, Charleston, SC

Haibo Yu^1*, Zhongxia Huang^2* and Wen Gao³

¹Capital Medical University, Department of Hematology, Beijing Chao-Yang Hospital, Capital Medical University, China, China
²Department of Hematology, Beijing Chao-Yang Hospital,, beijing, China
³Beijing Chao-Yang Hospital Affiliated to Capital Medical University, Beijing, CHN

Ella Willenbacher, MD, PhD^1*, Siegfried Sormann, MD^2*, Petra Pichler^3*, Krauth Maria-Theresa^4*, Hermine Agis, Prof MD⁵, Irene Strassl^6*, Klaus Podar, MD, PhD⁷, Roman Weger, Mag.^8* and Wolfgang Willenbacher, MD, PhD^9,10

¹Internal Med. V: Hematology & Oncology, Medical University of Innsbruck, Innsbruck, AUT
²Dep. of Hematology,, University Clinic for Internal Medicine, Graz, AUT
³Clinical Department for Internal Medicine, University Hospital St Poelten, Karl Landsteiner University of Health Sciences, St. Poelten, Austria
⁴Department Internal Medicine I, Division Hematology & Hemostaseology,, Medical University of Vienna, Wien, AUT
⁵Internal Med.I: Hematology & Hemostasiology, Medical University of Vienna, Wien, Wien, Austria
⁶Division of Hematology with Stem Cell Transplantation, Hemostaseology and Medical Oncology, Department of Internal Medicine I, Ordensklinikum Linz, Linz, Austria
⁷Division of Molecular Oncology and Hematology, Department of Basic and Translational Oncology, Karl Landsteiner University of Health Sciences, Krems an der Donau, Austria
⁸syndena GmbH, connect to cure, Innsbruck, AUT
⁹Department of Medicine V: Hematology & Oncology, Innsbruck Medical University, Innsbruck, Austria
¹⁰syndena GmbH, connect to cure, Innsbruck, Austria

Erin A. Dean, MD¹, Derek M. Li^1*, Tuo Lin, PhD^1*, Robert P. Seifert, MD^1*, Jack W. Hsu, MD^1*, John W. Hiemenz, MD^1* and John R. Wingard, MD²

¹University of Florida, Gainesville, FL
²University of Florida College of Medicine, Gainesville, FL

Rupayan Kundu, MD^1*, Niladri Kal^2*, Abhay Singh, MD, MPH³, Louis Williams, MD³, Jack Khouri, MD³, Christy J. Samaras, DO³, Jason Valent, MD³, Shahzad Raza, MD⁴, Willem Van Heeckeren, MD, PhD^3*, Faiz Anwer, MD³ and Sandra Mazzoni, DO⁵

¹Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH
²Department of Statistics, Texas A&M University, College Station, TX
³Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
⁴Department of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Overland Park, KS
⁵Department of Hematology and Medical Oncology, Taussig Cancer Center, Cleveland Clinic, Cleveland, OH

Saoirse Bodnar^1*, Tehilla Brander, MS, CGC^2*, Zachary M Avigan, MD¹, William Genthe^3*, David Melnekoff, PhD^4*, Alessandro Lagana, PhD⁵, Jane Houldsworth, PhD⁶, Shambavi Richard, MD⁴, Joshua Richter, MD⁴, Larysa J Sanchez, MD⁴, Cesar Rodriguez, MD⁴, Adriana Rossi, MD, MSc⁴, Hearn Jay Cho, MD, PhD⁴, Kenan Onel, MD, PhD^7*, Sundar Jagannath, MD⁴, Manisha Balwani, MD^2*, Samir Parekh, MD⁴ and Santiago Thibaud, MD¹

¹Department of Medicine, Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
²Icahn School of Medicine At Mount Sinai, New York, NY
³Icahn School of Medicine at Mount Sinai, New York, NY
⁴Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
⁵Department of Medicine, Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York
⁶Pathology, Icahn School of Medicine at Mount Sinai, New York, NY
⁷Clinical Genomics, Roswell Park Comprehensive Cancer Center, Buffalo, NY

J Christine Ye, MD, MSc¹, Guilin Tang, MD, PhD^2*, Oren Pasvolsky, MD^3*, Melody R. Becnel, MD³, Mahmoud R. Gaballa, MD³, Krina K. Patel, MD, MSc⁴, Hans C. Lee, MD⁵, Sheeba K. Thomas, MD⁶, Donna M. Weber, MD⁶, Pei Lin, MD, DM, MDPC⁷ and Robert Z. Orlowski, MD, PhD³

¹Department of Lymphoma & Myeloma, UT MD Anderson Cancer Center, Houston, TX
²Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Lymphoma & Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
⁴M.D. Anderson Cancer Center, MD Anderson Cancer Center, Houston, TX
⁵Department of Lymphoma & Myeloma, MD Anderson Cancer Center, Houston, TX
⁶Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
⁷Department of Hematopathology, M.D. Anderson Cancer Center, Houston, TX

Saad Z. Usmani, MD¹, Emily A. Semmel, MS^2*, Shandra James^2*, William A. Wood, MD, MPH³, Mark A. Schroeder, MD⁴, David J. Chung, MD, PhD⁵, Aaron S. Rosenberg, MD⁶, Jeffrey A. Zonder, MD ⁷, Samuel M. Rubinstein, MD⁸, Anita D'Souza, MD⁹, Thomas Martin, MD¹⁰, Ajai Chari, MD¹¹, Ravi Vij, MD, MBA⁴, Ajay K. Nooka, MD, MPH¹², Kenneth C. Anderson, MD¹³, Donna S. Neuberg, ScD¹⁴, Kathleen Hewitt, DNP, RN^15*, Brendan M. Weiss, MD¹⁶, Levi D. Pederson, MS^17*, Andriy Derkach, PhD^18*, Susan M. Geyer, PhD¹⁹ and Shaji Kumar, MD²⁰

¹Myeloma Service, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
²ASH Research Collaborative, Washington, DC
³Division of Hematology/Oncology, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC
⁴Division of Oncology, Washington University School of Medicine, St. Louis, MO
⁵Transplant and Cellular Therapy Services, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁶UC Davis Comprehensive Cancer Center, Sacramento, CA
⁷Karmanos Cancer Institute, Detroit, MI
⁸Division of Hematology, University of North Carolina School of Medicine, Chapel Hill, NC
⁹Center for International Blood and Marrow Transplant Research, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI
¹⁰Department of Hematology, University of California at San Francisco, San Francisco, CA
¹¹University of California, San Francisco, San Francisco, CA
¹²Winship Cancer Institute of Emory University, Atlanta
¹³Dana-Farber/Boston Children's Cancer and Blood Disorders Ctr, Boston, MA
¹⁴Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
¹⁵ASH Research Collaborative, Gainesville, VA
¹⁶Moderna, Inc., Cambridge, MA
¹⁷Mayo Clinic, Rochester, MN
¹⁸Department of Biostatistics and Epidemiology, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁹Alliance Statistics and Data Management Center, Mayo Clinic, Rochester, MN
²⁰Division of Hematology, Mayo Clinic, Rochester, MN