Riccardo Moia, MD^1*, Maria Elena Carazzolo^2*, Chiara Cosentino^1*, Mohammad Almasri^1*, Donatella Talotta^1*, Valentina Tabanelli^3*, Giovanna Motta^4*, Federica Melle, PhD^5*, Maria Vittoria Sacchi^6*, Andrea Evangelista^7*, Luca Cividini^8*, Maria Chiara Tisi^9*, Merli Anna^10*, Stefano Fiori^5*, Alessandro Re, MD^11*, Claudia Castellino^12*, Vittorio Ruggero Zilioli^13*, Francesco Piazza, MD^14*, Paolo Corradini, MD¹⁵, Stefan Hohaus^16*, Gerardo Musuraca, MD, PhD^17*, Francesca Gaia Rossi, MD^18*, Benedetta Puccini, MD^19*, Federica Cavallo^20*, Filippo Ballerini^21*, Roberta Sciarra^22*, Alice Di Rocco, MD^23*, Annalisa Arcari^24*, Carola Boccomini^25*, Francesco Merli, MD^26*, Guido Gini, MD²⁷, Monica Tani^28*, Riccardo Bruna, MD^29*, Vincenzo Pavone, MD^30*, Marco Ladetto, MD³¹, Sara Galimberti, MD^32*, Riccardo Bomben, PhD^33*, Valter Gattei, MD³³, Ilaria Del Giudice^34*, Simone Ferrero, MD³⁵, Stefano Pileri³, Monica Balzarotti^36*, Gianluca Gaidano, MD, PhD³⁷ and Carlo Visco, MD^38*

¹Division of Hematology, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy
²Department of Medicine, Section of Hematology, University of Verona, Verona, Italy
³Haematopathology Division, IEO European Institute of Oncology IRCCS, Milan, Italy
⁴Haematopathology Unit, IRCCS Azienda Ospedaliero-Universitaria of Bologna, Bologna, Italy
⁵IEO, Istituto Europeo di Oncologia IRCCS - Haematopathology Division, Milano, Italy
⁶Fondazione Italiana Linfomi, Onlus, Alessandria, Alessandria, Italy
⁷SSD Epidemiologia Clinica e Valutativa, AOU Città della Salute e della Scienza e CPO Piemonte, Torino, Italy
⁸Università Del Piemonte Orientale, Novara, ITA
⁹Hematology Unit, San Bortolo Hospital, A.U.L.S.S. 8 "Berica", Vicenza, Italy
¹⁰Ospedale degli Infermi di Rimini - U.O. di Ematologia, Rimini, Italy
¹¹Lymphoma Unit, Division of Hematology, ASST Spedali Civili di Brescia, Brescia, Italy
¹²A.O. S. Croce e Carle - S.C. di Ematologia e Trapianto di Midollo Osseo, Cuneo, Italy
¹³Division of Hematology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, Milano, IT-MI, Italy
¹⁴12Dipartimento di Medicina, Università degli Studi di Padova, UOC di Ematologia, Azienda Ospedale Università Padova, Padova, Italy
¹⁵Hematology Division, University of Milan. Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy
¹⁶Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy
¹⁷IRCCS Istituto Romagnolo per lo studio dei Tumori (IRST) “Dino Amadori”, Meldola, Italy
¹⁸Ospedale Maggiore Policlinico - Fondazione IRCCS Ca Granda – Ematologia, Milano, Italy
¹⁹Unit of Hematology, Careggi University-Hospital, Florence, Italy
²⁰Division of Hematology, University of Torino, Torino, Italy
²¹IRCCS Ospedale Policlinico San Martino, Genoa, Italy
²²Fondazione IRCCS Policlinico San Matteo, Pavia, ITA
²³Hematology Section, Department of Traslational and Precision Medicine, Sapienza University of Rome, Roma, Italy
²⁴UO Ematologia, Ospedale Guglielmo da Saliceto, Piacenza, Italy
²⁵SC Ematologia, AOU Città della Salute e della Scienza, Torino, Italy
²⁶Hematology unit, Azienda USL-IRCCS, Reggio Emilia, Italy
²⁷Hematology Unit, AUO Ospedali Riuniti, Università Politecnica delle Marche, Ancona, ITA
²⁸Santa Maria delle Croci Hospital, Ravenna, Italy
²⁹Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont and AOU Maggiore della Carità, Novara, ITA
³⁰Hematology Unit, Azienda C. Panico, Tricase, Italy
³¹Department of Translational Medicine, Università del Piemonte Orientale ed SCDU Ematologia AOU SS Antonio e Biagio e Cesare Arrigo, Alessandria, Piedmont, Italy
³²Department of Clinical and Experimental Medicine, Hematology, University of Pisa, Pisa, Italy
³³Clinical and Experimental Onco-Hematology Unit, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy
³⁴Hematology, Department of Translational and Precision Medicine, Sapienza University, Roma, Italy
³⁵Department of Molecular Biotechnology and Health Sciences, Hematology Division, University of Torino, Torino, TO, Italy
³⁶Hematology, IRCCS Humanitas Research Hospital, Rozzano, Milano, ITA
³⁷Division of Hematology, Department of Translational Medicine, University of Eastern Piedmont, Novara, Italy
³⁸Hematology and Bone Marrow Transplant Unit, Department of Engineering for Innovative Medicine, University of Verona, Verona, Italy

Ilaria Romano, MD^1,2, Joyce Marques De Almeida, MD^2*, Lodovico Terzi Di Bergamo^2*, Alessio Bruscaggin, PhD^2*, Saemi Schaer^3*, Riccardo Moia, MD^4*, Deborah Piffaretti, PhD^5*, Maria Cristina Pirosa, MD^1,2, Adalgisa Condoluci, MD^1,2, Gabriela Forestieri^2*, Federico Jauk, MD^2*, Matin Salehi^2*, Georgia Alice Galimberti^2*, Simone Bocchetta, PhD^2*, Francesco Bertoni, MD⁶, Urban Novak, MD^7*, Felicitas Hitz, MD^8*, Stefan Dirnhofer, MD^9*, Jana Musilova^3*, Andrea Fuhrer^3*, Stefanie Hayoz^3*, Luca Ceriani, MD^10*, Gianluca Gaidano, MD, PhD⁴, Anastasios Stathis, MD^11,12*, Emanuele Zucca, MD^13,14 and Davide Rossi, MD, PhD^1,2,14

¹Clinic of Hematology, Oncology Institute of Southern Switzerland, Ente Ospedaliero Cantonale, Bellinzona, Switzerland
²Institute of Oncology Research, Laboratory of Experimental Hematology, Bellinzona, Switzerland
³Swiss Group for Clinical Cancer Research (SAKK) Competence Center, Bern, Switzerland
⁴Division of Hematology, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy
⁵Institute of Oncology Research, Laboratory of Experimental Hematology, Bellinzona, AL, Switzerland
⁶Lymphoma Genomics, Institute of Oncology Research, Bellinzona, Switzerland
⁷Department of Medical Oncology, University Hospital Inselspital and University of Bern, Bern, Switzerland
⁸Oncology/Hematology, Kantonsspital St.Gallen, St. Gallen, Switzerland
⁹Institute of Pathology and Medical Genetics, University Hospital Basel, Basel, Switzerland
¹⁰Imaging Institute of Southern Switzerland, Clinic of Nuclear Medicine and Molecular Imaging, Bellinzona, Switzerland
¹¹Oncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale, Bellinzona, Switzerland
¹²Faculty of Biomedical Sciences, Università della Svizzera Italiana, Lugano, Switzerland
¹³Division of Medical Oncology, Oncology Institute of Southern Switzerland (IOSI), Ente Ospedaliero Cantonale, Bellinzona, Switzerland
¹⁴Università della Svizzera italiana, Faculty of Biomedical Science, Lugano, Switzerland

Xu Sun, PhD^1,2,3*, Yijun Wu, MD^2,3,4*, Kai Kang, MD^2,3,5*, He Li, MD^1*, Ailin Zhao, MD^6,7,8* and Ting Niu, MD, PhD^1,2,3

¹Department of Hematology, West China Hospital, Sichuan University, Chengdu, China
²National Facility for Translational Medicine (Sichuan), West China Hospital, Sichuan University, Chengdu, China
³State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University, Chengdu, China
⁴Division of Thoracic Tumor Multimodality Treatment, Cancer Center, West China Hospital, Sichuan University, Chengdu, AL, China
⁵Division of Thoracic Tumor Multimodality Treatment, Cancer Center, West China Hospital, Sichuan University, Chengdu, China
⁶National Facility for Translational Medicine (Sichuan), West China Hospital, Sichuan University., Chengdu, China
⁷Department of Hematology, West China Hospital, Sichuan University., Chengdu, China
⁸State Key Laboratory of Biotherapy, Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University., Chengdu, China

Cristiana Carniti^1*, Sadhana Jonnalagadda^1*, Giada Zanirato^1*, Martina Magni^1*, Eugenio Fardella, MD^2*, Claudia Castellino^3*, Alessandro Re, MD^4*, Chiara Ghiggi^5*, Filippo Ballerini^6*, Rosanna Ciancia^7*, Lorella Orsucci^8*, Antonio Pinto^9,10*, Sara Usai^11*, Francesca Gaia Rossi, MD^12*, Annalisa Arcari^13*, Fiorella Ilariucci^14*, Vittorio Ruggero Zilioli^15*, Leonardo Flenghi^16*, Melania Celli^17*, Fabio Benedetti^18*, Caterina Patti^19*, Caterina Plenteda^20*, Manuela Zanni^21*, Gerardo Musuraca^22*, Riccardo Bruna^23*, Luca Arcaini^24*, Federica Cavallo^25*, Annalisa Chiappella¹, Anna Dodero, MD^26* and Paolo Corradini, MD²⁷

¹Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy
²Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy
³A.O. S. Croce e Carle - S.C. di Ematologia e Trapianto di Midollo Osseo, Cuneo, Italy
⁴Lymphoma Unit, Division of Hematology, ASST Spedali Civili di Brescia, Brescia, Italy
⁵UO Ematologia e Terapie Cellulari, IRCCS Ospedale Policlinico San Martino, Genova, Italy
⁶Hematology, IRCCS Ospedale Policlinico San Martino, Genova, Italy
⁷Onco-hematology and Stem Cell Transplantation and Cellular Therapies,, Centro di Riferimento Oncologico di Aviano (CRO) IRCCS, Aviano, Italy
⁸Hematology Division, A.O.U Città della Salute e della Scienza, Ospedale S. Giovanni Battista Molinette, Torino, Italy
⁹Hematology-Oncology & Stem Cell Transplantation Unit, IRCCS Istituto Nazionale Tumori, Fondazione G. Pascale, Napoli, Italy
¹⁰Hematology-Oncology and Stem Cell Transplantation Unit, Istituto Nazionale Tumori, Fondazione ‘G. Pascale’, IRCCS, Naples, Italy
¹¹SC Ematologia e CTMO ARNAS G. Brotzu, Cagliari, Italy
¹²Ospedale Maggiore Policlinico - Fondazione IRCCS Ca Granda – Ematologia, Milano, Italy
¹³UO Ematologia, Ospedale Guglielmo da Saliceto, Piacenza, Italy
¹⁴Hematology, Azienda USL-IRCCS di Reggio Emilia,, Reggio Emilia, Italy
¹⁵Division of Hematology, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy, Milano, IT-MI, Italy
¹⁶Hematology, Azienda Ospedaliera di Perugia, Perugia, Italy
¹⁷Ospedale Degli Infermi Di Rimini, Rimini, Italy
¹⁸Department of Engineering for Innovation Medicine, Section of Medicine and Bone Marrow Transplant Unit, Verona University, Verona, Italy
¹⁹Onco-Hematology Unit, Azienda Ospedaliera Riunita Villa Sofia-Vincenzo Cervello, Palermo, Italy
²⁰Hematology and CTMO, Azienda Ospedaliera-Universitaria di Parma, Parma, Italy
²¹Department of Translational Medicine, Università del Piemonte Orientale SCDU Ematologia, AO SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy
²²Hematology unit, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori", Meldola, Italy
²³Division of Hematology, Ospedale Maggiore Della Carità, Novara, Italy
²⁴Division of Hematology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
²⁵Division of Hematology, AOU Città della Salute e della Scienza di Torino, Torino, Italy
²⁶Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milano, Italy
²⁷Fondazione IRCCS Istituto Nazionale dei Tumori Milano, University of Milano, Milano, Italy

Christopher J. Forlenza, MD¹, David Hoogstra, MD^2*, Donald Barkauskas, PhD^3*, Lauren Saguilig, MS^4*, Suzanne D. Turner, PhD^5*, Nina Prokoph, PhD^6*, Perla Pucci, PhD^6*, Lucy Hare, BMBS, PhD^6*, Leila Jahangiri, PhD^6*, Rui Wu, MD, PhD^7*, Kojo S.J. Elenitoba-Johnson, MD¹, Eric J. Lowe, MD⁸ and Megan S. Lim, MD, PhD^1*

¹Memorial Sloan Kettering Cancer Center, New York, NY
²Helen Devos Children's Hospital At Spectrum Health, Grand Rapids, MI
³Children’s Oncology Group Operations Statistics and Data Center, Monrovia, CA
⁴Children's Oncology Group Statistical Center, Monrovia, CA
⁵University of Cambridge, Department of Pathology, Cambridge, United Kingdom
⁶University of Cambridge, Cambridge, United Kingdom
⁷Memorial Sloan Kettering Cancer Center, New York
⁸Children's Hospital of the King's Daughters, Norfolk, VA

Irit Mazza Avivi, MD^1,2*, Miriam Neaman, MD^1,3*, Noa Lowenton-Spier^1*, Chava Perry, MD^1,2*, Erel Joffe, MD^1*, Roy Vitkon, MD^1*, Vlada Bogol, MSc^1*, Yael Michaeli, Phd^4*, Noa Gilat, Phd^4*, Lynne Itelson, MSc^4*, Shahar Zirkin, Phd^4*, Jasline Deek, Phd^3*, Efstathios Kastritis, MD^5*, Karolis Sablauskas, MD^6,7*, Skirmante Cernauskiene, MD^7*, Vilmantė Vaitekėnaitė, MD^7*, Andrius Zucenka, MD^8,9, Tomas Papajik, MD, PhD^10*, Eva Kriegova, PhD^11*, Petr Gajdos^12* and Yuval Ebenstein, Phd^3,13*

¹Department of Hematology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
²Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
³Department of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv, Israel
⁴JaxBio Technologies Ltd., Netanya, Israel
⁵Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
⁶Institute of Data Science and Digital Technologies, Vilnius University, Vilnius, Lithuania
⁷Hematology, Oncology and Transfusion Medicine Center, Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania
⁸Vilnius University Hospital Santaros Klinikos, Vilnius, Lithuania
⁹Hematology and Oncology Department, Faculty of Medicine, Vilnius University, Vilnius, Lithuania
¹⁰Department of Hemato-Oncology, Faculty of Medicine and Dentistry, Palacky University and University Hospital, Olomouc, Czech Republic
¹¹Department of Immunology, Faculty of Medicine and Dentistry, Palacky University and University Hospital, Olomouc, Czech Republic
¹²Department of Computer Science, Faculty of Electrical Engineering and Computer Science, Technical University of Ostrava, Ostrava, Czech Republic
¹³Department of Biomedical Engineering, Faculty of Engineering, Tel Aviv Univesity, Tel Aviv, Israel

Samuel Weinschenk, BSc^1*, Ulrike Philipp^1*, Julia C. Kuehn, MD^1*, Katharina J. Müller, MD^2*, Josia Fauser, MD^3*, David Böckle, MD^4*, Inga Gebhard^1*, Marta Hinz, BSc^1*, Nicolas N. Neidert, MD^5*, Sabine Bleul^1*, Eliza M. Lauer, MD^1*, Jurik A. Mutter, PhD^1,6*, Stefan K. Alig, MD⁶, David Kurtz, MD, PhD⁶, Jürgen Finke, MD¹, Reinhard Marks, MD^1*, Maximilian Diehn, MD, PhD^7*, Ash A. Alizadeh, MD, PhD⁶, Peter C. Reinacher, MD^8*, Julius Wehrle, MD^1*, Dominik Wolf, M.D.^9*, Florian Kocher, MD, PhD^3*, Björn Chapuy¹⁰, Jürgen Beck, MD^11*, Marco Prinz, MD^12,13*, Louisa von Baumgarten, MD^2*, Elisabeth Schorb, MD^1*, Justus Duyster, MD^14* and Florian Scherer, MD^1,15

¹Department of Medicine I, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
²Department of Neurology, Ludwig-Maximilians-University of Munich, Munich, Germany & German Cancer Consortium, Partner Site Munich, Munich, Germany
³Department of Internal Medicine V, Haematology & Oncology, Comprehensive Cancer Center Innsbruck (CCCI) and Tyrolean Cancer Research Institute (TKFI), Medical University of Innsbruck (MUI), Innsbruck, Austria
⁴Department of Hematology, Oncology and Tumor Immunology, Charité - University Medical Center Berlin, Campus Benjamin Franklin, 12203 Berlin, Germany, Berlin, Germany
⁵Department of Neurosurgery, Medical Center-University of Freiburg, University of Freiburg, Freiburg, Germany
⁶Department of Medicine, Divisions of Oncology and Hematology, Stanford University, Stanford, CA
⁷Department of Radiation Oncology, Stanford University Medical Center, Stanford, CA
⁸Department of Stereotactic and Functional Neurosurgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
⁹University Hospital of Internal Medicine V (Hematology and Oncology), Medical University of Innsbruck, Anichstraße 35, 6020, Innsbruck, Austria
¹⁰Hematology, Oncology and Cancer Immunology, Charité - University Medical Center Berlin, Campus Benjamin Franklin, Berlin, Germany
¹¹Department of Neurosurgery, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
¹²Institute of Neuropathology, Medical Faculty, University of Freiburg, Freiburg, Germany
¹³Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany
¹⁴Department of Medicine I, Hematology, Oncology and Stem Cell Transplantation, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
¹⁵German Cancer Consortium (DKTK) partner site Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany

Minghao Dang, PhD^1*, Sherif Seif, MD^2*, Maria Jose Acevedo-Calado, PhD^1*, Linghua Wang, MD, PhD, MS^3*, Bria Gabriel^2*, Lauren S. Lewis^2*, Lorenzo Gensini, MD^2*, Hima Bansal, PhD^1*, Melody R. Becnel, MD¹, Mahmoud R. Gaballa, MD¹, Hans C. Lee, MD⁴, Oren Pasvolsky, MD¹, Krina K. Patel, MD, MSc², Donna M. Weber, MD¹, J Christine Ye, MD^1*, Robert Z. Orlowski, MD, PhD¹ and Sheeba K. Thomas, MD²

¹Department of Lymphoma & Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Genomic Medicine, MD Anderson Cancer Center, Houston, TX
⁴Department of Lymphoma & Myeloma, MD Anderson Cancer Center, Houston, TX

Archibald Enninful^1*, Francine M. Foss, MD², Rong Fan, PhD^3* and Mina Xu, MD^4*

¹Biomedical Engineering, Yale University `, New Haven, CT
²Yale University School of Medicine, Hamden, CT
³Department of Biomedical Engineering, Yale University, New Haven, CT
⁴Yale University, New Haven, CT

Evgeny Arons, PhD^1*, Chin-Hsien Tai, PhD^2*, Suraj Joshi, BSc^3*, Yuelin Liu^3*, Chi-ping Day^3*, Mark Raffeld, MD^4*, Liqiang Xi, MD^4*, Hong Zhou, BS^1*, Mory Gould^2*, Isaac Shpilman^5*, Christopher C. Oakes, PhD^6,7,8, Seema A Bhat, MD⁹, Michael R. Grever, MD⁹, Kerry A. Rogers, MD⁹, Hao-Wei Wang, MD, PhD^4*, Constance M. Yuan, MD, PhD^4*, Cenk Sahinalp^10* and Robert J. Kreitman, MD¹

¹Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD
²Laboratory of Molecular Biology, National Cancer Institute, Bethesda, MD
³Cancer Data Science Laboratory, National Cancer Institute, Bethesda, MD
⁴Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD
⁵Laboratory of Molecular Biology, National Cancer Institute, NIH, Bethesda, MD
⁶Department of Biomedical Informatics, The Ohio State University, Columbus, OH
⁷Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus
⁸Division of Hematology, Department of Internal Medicine, Comprehensive Cancer Center, The Ohio State University, Columbus, OH
⁹Division of Hematology, The Ohio State University, Columbus, OH
¹⁰Cancer Data Science Laboratory, National Cancer Institute, NIH, Bethesda, MD

Bartosz Szmyd, MD^1,2*, Kamila Wypyszczak, M.Sc.^3,4*, Karolina Miarka-Walczyk, M.Sc.^3,4*, Zuzanna Urbanska^3,4*, Karolina Krajewska, M.D., Ph.D.^3*, Justyna Walenciak, M.D., Ph.D.^3*, Agnieszka Wziatek, M.D., Ph.D.^5*, Katarzyna Derwich, Prof., M.D., Ph.D.^5*, Eryk Latoch, M.D., Ph.D.^6*, Maryna Krawczuk-Rybak, Prof., M.D., Ph.D.^6*, Dawid Przystupski, M.D.^7*, Bernarda Jadwiga Kazanowska, Prof., M.D., Ph.D.^7*, Ninela Irga-Jaworska, Prof., M.D., Ph.D.^8*, Monika Radwanska, MD, PhD^9*, Ewa Dudkiewicz, M.D., Ph.D.^10*, Bozenna Dembowska-Baginska, Prof., M.D., Ph.D.^11*, Anna Wakulinska, M.D.^11*, Katarzyna Babol-Pokora, Ph.D.^3*, Tomasz Szczepanski, Prof., M.D., Ph.D.¹², Wojciech Mlynarski, Prof., M.D., Ph.D.^3* and Agata Pastorczak, Prof., M.D., Ph.D.^3,4*

¹Department of Neurosurgery and Neurooncology, Barlicki University Hospital, Lodz, Poland, Medical University of Lodz, Lodz, Poland
²Department of Pediatrics, Oncology and Hematology, Medical University of Lodz, Lodz, AL, Poland
³Department of Pediatrics, Oncology and Hematology, Medical University of Lodz, Lodz, Poland
⁴Department of Genetic Predisposition to Cancer, Medical University of Lodz, Lodz, Poland
⁵Department of Pediatric Oncology, Hematology and Transplantology, Poznan University of Medical Sciences, Poznan, Poland
⁶Department of Pediatric Oncology and Hematology, Medical University of Bialystok, Bialystok, Poland
⁷Department of Pediatric Hematology/Oncology and BMT, Wroclaw Medical University, Wroclaw, Poland
⁸Department of Pediatrics, Hematology and Oncology, Medical University of Gdańsk, Gdańsk, Poland
⁹Department of Pediatric Oncology and Hematology, College of Medical Sciences, University of Rzeszów, Rzeszow, Poland
¹⁰Department of Pediatric Hematology, Oncology and Transplantology, Medical University of Lublin, Lublin, Poland
¹¹Department of Oncology, The Children's Memorial Health Institute, Warsaw, Poland
¹²Department of Pediatric Hematology and Oncology, Medical University of Silesia, Zabrze, Poland

Steven Wang, MD^1*, Parisa Mapar^2*, Ymke van der Pol, PhD^2*, Norbert Moldovan, PhD^2*, Normastuti Adhini Tantyo^2*, Erik D. van Werkhoven, PhD^3,4*, Bart Snieder^2*, André Do Brito Valente^2*, A. De Jonge^5*, Esther Drees, MD^2*, Margaretha G.M. Roemer, PhD^2*, Bauke Ylstra, PhD^6*, Clara Klerk, MD PhD^7*, Leonie Strobbe, MD^8*, Yorick Sandberg, MD PhD^9*, Rinske Boersma^10*, Harry R. Koene, MD PhD^11*, Hans Pruijt, MD, PhD^12*, Koen de Heer, MD, PhD^13*, Rozemarijn van Rijn^14*, Yavuz M. Bilgin, MD PhD^15*, Eva De Jongh, MD^16*, Marcel Nijland, MD, PhD^17*, Marjolein W.M. van der Poel^18*, Ad Koster^19*, Laurens Nieuwenhuizen, MD PhD^20*, Rob Fijnheer, MD PhD^21*, Aart Beeker, MD²², Rogier Mous, MD PhD^23*, Vibeke KJ Vergote, MD^24*, Joost S.P. Vermaat²⁵, Dirk Michiel Pegtel, PhD^26*, Martine E.D. Chamuleau, MD PhD²⁷ and Florent Mouliere, PhD^2,28*

¹Department of Hematology, Amsterdam UMC Location Vrije Universiteit, Amsterdam, Netherlands
²Amsterdam UMC, Amsterdam, Netherlands
³Erasmus University Medical Center Cancer Institute, Rotterdam, Netherlands
⁴HOVON Foundation, Rotterdam, Netherlands
⁵Cancer Biology and Immunology, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, Netherlands
⁶VU University Medical Center, Amsterdam, Netherlands
⁷Department of Internal Medicine, Dijklanderziekenhuis, Hoorn, Netherlands
⁸Department of Internal Medicine, Gelreziekenhuizen, Zutphen, Netherlands
⁹Department of Internal Medicine, Maasstad Hospital, Rotterdam, Netherlands
¹⁰Amphia Hospital Breda, Breda, Netherlands
¹¹St. Antonius Hospital, Nieuwegein, NLD
¹²Jeroen Bosch Ziekenhuis, S-Hertogenbosch, Netherlands
¹³Department of Internal Medicine, Flevoziekenhuis, Almere, Netherlands
¹⁴Medisch Centrum Leeuwarden, Leeuwarden, Netherlands
¹⁵Adrz, Goes, Netherlands
¹⁶Albert Schweitzer Hospital, Dordrecht, Netherlands
¹⁷University Medical Center Groningen and University of Groningen, Groningen, Netherlands
¹⁸Department of Internal Medicine, Division of Hematology, GROW school for Oncology and Developmental Biology, Maastricht University Medical Center, Maastricht, Netherlands
¹⁹VieCuri, Venlo, Netherlands
²⁰Department of Internal Medicine, Máxima Medisch Centrum, Eindhoven, Netherlands
²¹Department of Internal Medicine, Meander Medisch Centrum, Amersfoort, Netherlands
²²Spaarne Ziekenhuis, Hoofddorp, Netherlands
²³Department of Hematology, University Medical Center Utrecht, Utrecht, Netherlands
²⁴Department of Hematology, University Hospitals Leuven, Leuven, Belgium
²⁵Department of Hematology, Leiden University Medical Center, Leiden, Netherlands
²⁶Amsterdam UMC, Location VUMC, Amsterdam, Netherlands
²⁷Department of Hematology, Amsterdam UMC location Vrije Universiteit Amsterdam, Amsterdam, Netherlands
²⁸Cancer Research UK National Biomarker Centre, University of Manchester, Manchester, United Kingdom

Anu Amallraja^1*, Gunes Gundem^1*, Dylan Domenico^1*, Juan E Arango Ossa^1*, Umut Aypar, PhD^2*, Jeeyeon Baik, BA, MPH^2*, Michael Kluk^3*, Shenon Sethi, MBBS^2*, Katherine Lopez^2*, David A. Qualls, MD⁴, Gilles Salles, MD, PhD⁵, Elli Papaemmanuil¹, Pallavi Galera, MBBS² and Ahmet Dogan, MD, PhD⁶

¹Department of Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY
²Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
³Department of Pathology and Laboratory Medicine, Weill Cornell Medicine/New York Presbyterian Hospital, New York, NY
⁴Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁵Lymphoma Service Chief, Memorial Sloan Kettering Cancer Center, New York, NY
⁶Memorial Sloan Kettering Cancer Center, New York, NY

Qianru Zhang^1*, Wenqiang Yan^2*, Lu Sun^1*, Guoqing Han^3*, Qiaoli Wu^4*, Yiran Cui^1*, Bolin Liu^1*, Feng Zhang^1*, Ke Pu^3*, Mingchao Zhang^3*, Xiaobing Zhang^1*, Lugui Qiu¹, Qingguo Li^4*, Gang An^1* and Yuxuan Liu^5*

¹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology& Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
²State Key Laboratory of Experimental Hematology, State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood, TIANJIN, China
³Department of Neurosurgery, Tianjin Huanhu Hospital, Tianjin, China
⁴Tianjin Neurosurgical Institute, Tianjin Key Laboratory of Cerebrovascular and Neurodegenerative Diseases, Tianjin Huanhu Hospital, Tianjin, China
⁵State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology& Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Dallas, TX

Eric Liu^1*, Amit Verma, MD², Kith Pradhan, PhD^3*, Urvi A. Shah, MD⁴, Aditi Shastri, MD⁵, Erik Guillen, MSc^6*, Alejandro Sica, MD^7*, Gregoire Lauvau, PhD^8*, Murali Janakiram, MBBS⁹ and Paul D. Kassner, Ph.D.^10*

¹Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY
²Department of Developmental & Molecular Biology, Albert Einstein College of Medicine, Bronx
³Montefiore Einstein Cancer Center, Blood Cancer Institute, Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY
⁴Myeloma Service, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁵Blood Cancer Institute, Department of Oncology, University of Vermont, Bronx, NY
⁶Albert Einstein College of Medicine, Bronx, NY
⁷Department of Oncology, Montefiore Medical Center and Albert Einstein College of Medicine, Bronx, NY
⁸Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY
⁹Montefiore Medical Center, Bronx, NY
¹⁰RAPT Therapeutics, Inc., South San Francisco, CA

Mathieu Simonin^1*, Mathieu Viennot^2*, Stéphanie Haouy^3*, Stéphane Ducassou^4*, Aurélie Phulpin^5*, Nathalie Garnier^6*, Catherine Curtillet^7*, Catherine Paillard, MD, PHD^8*, Melissa Barbati^9*, Jacinthe Bonneau-Lagacherie^10*, Marie-Laure Couec^11*, Frederic Millot^12*, Liana Carausu^13*, Justyna Kanold^14*, Isabelle Pellier, PhD^15*, Pascale Schneider, MD, PhD^16*, Jean-Louis Stephan^17*, Camille Leglise^18*, Claire Pluchart, MD^19*, Charlotte Rigaud, MD^20*, Marie-Emilie Dourthe, MD, PhD^21*, Pierre-Julien Viailly, PhD^2*, Pascaline Etancelin, PharmD^22*, Victor Michel, MD^23*, Sabah Boudjemaa^24*, Bénédicte Jonca^25*, Françoise Montravers^25*, Thierry Leblanc^26*, Judith Landman-Parker^27* and Fabrice Jardin, MD, PhD^28*

¹Sorbonne Université / Trousseau Hospital, Paris / APHP, Paris, France
²INSERM U1245, Cancer and Brain Genomics, Centre Henri Becquerel, University of Rouen, Rouen, France
³CHU Montpellier, Montpellier, France
⁴CHU de Bordeaux, Hopital Pellegrin, Bordeaux, France
⁵Pediatric Oncology and Hematology Department, University Hospital of Nancy, Nancy, France
⁶IHOPE Lyon, Lyon, France
⁷Department of Pediatric Hematology and Oncology, APHM, La Timone Hospital, Marseille., Marseille, France
⁸Pediatric Oncology, CHRU Strasbourg, Strasbourg, FRA
⁹Department of Pediatric Hematology-Oncology, CHRU Lille, Lille, France, Lille, France
¹⁰Department of Pediatric Hematology and Oncology, Rennes University Hospital, Rennes, France, Rennes, France
¹¹Pediatric hematology and oncology department, University Hospital of Nantes, Nantes, Nantes, France
¹²Pediatric Oncology, CHU Poitiers, Poitiers, France
¹³Department of Pediatric Hematology and Oncology,, Centre Hospitalo-Universitaire de Brest, Brest, France, Brest, France
¹⁴Pediatric Oncoloy, CHU Clermont Ferrand, Clermontferrand, FRA
¹⁵Pediatric Oncology, CHU Angers, Angers Cedex, FRA
¹⁶Pediatric Hematology, Immunology, Oncology and Stem Cells Transplantation, Rouen University Hospital Charles Nicolle CHU Rouen, Rouen, France
¹⁷Department of Pediatrics Centre Hospitalier Universitaire Saint-Etienne, Saint-Priest en Jarez, France
¹⁸Department of Pediatric Oncology, Hematology, Immunology,, University Hospital of Amiens, Amiens, France
¹⁹Pediatric Oncology, CHU de Reims, Reims, FRA
²⁰Pediatric Hematology Department, Gustave Roussy, Villejuif, France
²¹Department of Pediatric Hematology and Immunology, University Hospital Robert Debré, Assistance Publique des Hôpitaux de Paris (APHP), Paris, France
²²Department of Genetic Oncology and Inserm U1245, Centre Henri Becquerel, Rouen, FRA
²³Department of Hematology, Center Henri Becquerel, University of Rouen, INSERM UMR1245, Rouen, France, Rouen, France
²⁴Pathology Department, Armand Trousseau University Hospital, AP-HP, Sorbonne Université, Paris, France, Paris, France
²⁵Department of nuclear medicine, University Hospital Tenon, Paris, Paris, France
²⁶Hopital Universitaire Robert-Debré, Paris, France
²⁷Sorbonne Université APHP Hôpital Armand Trousseau, Paris, France
²⁸Department of Hematology, Centre Henri Becquerel, Rouen, France

Anastasia Sobol, MS^1*, Stepan Kuznetsov, BS^1*, Anton Kremlev, MD^1*, Giorgio Inghirami, MD^2*, Nathan Fowler, MD¹, Nikita Kotlov, PhD^3* and Anastasia Nikitina, PhD^1*

¹BostonGene, Corp., Waltham, MA
²Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, NY
³BostonGene Corp., Waltham, MA

Emil Ramsø Kyvsgaard^1,2,3*, Morten Grauslund^4*, Lene Sjö^5,6*, Linea Melchior^7*, Trine Grantzau^4*, Lise Mette Gjerdrum^8*, Trine Trab^9*, Lærke Sloth Andersen^10*, Anne Ortved Gang, MD^11*, Marie Fredslund Breinholt^12*, Michael Boe Møller^13*, Jacob Haaber Christensen, MD, PhD^14*, Thomas Stauffer Larsen, MD, PhD^15,16*, Michael Roost Clausen, MD, PhD^17,18*, Anna Caroline Hasselbalch Riley, MD^1,19*, Carsten Utoft Niemann, MD, PhD^19,20*, Kirsten Gronbaek, MD, PhD, PR^20,21,22,23, Martin Hutchings, MD, PhD^19,24 and Simon Husby, MD, PhD^2*

¹Phase 1 Unit, Rigshospitalet, Copenhagen, Denmark
²Rigshospitalet, Department of Hematology, Copenhagen, Denmark
³Grønbæk Group, Biotech Research and Innovation Centre, BRIC, University of Copenhagen, Copenhagen, Denmark
⁴Dept, of Pathology, Rigshospitalet, Copenhagen, Denmark, Copenhagen, DNK
⁵Department of Pathology, Rigshospitalet, Copenhagen, Denmark
⁶University of Copenhagen, Copenhagen, DNK
⁷Dept. of Pathology, Rigshospitalet, Copenhagen Ø, DNK
⁸Zealand University Hospital, Roskilde, DNK
⁹Dept. Of Hematology, Rigshospitalet, Copenhagen, Denmark, Copenhagen, DNK
¹⁰Dept. of Hematology, Rigshospitalet, Copenhagen, Denmark, Copenhagen, DNK
¹¹Copenhagen University Hospital, Herlev, Denmark
¹²Dept. of Pathology, Herlev Hospital, Copenhagen, Denmark
¹³Pathology, Odense University Hospital, Odense, Denmark
¹⁴Dept. of Hematology, Odense University Hospital, Odense, Denmark
¹⁵Department of Hematology, Odense University Hospital, Odense, Denmark, Odense, Denmark
¹⁶Department of Clinical Research, University of Southern Denmark, Odense, Denmark
¹⁷Aarhus University Hospital, Vejle, DNK
¹⁸Vejle Hospital, Vejle, Denmark
¹⁹Department of Hematology, Rigshospitalet, Copenhagen, Denmark
²⁰Department of Clinical Medicine, Faculty of Health Science, University of Copenhagen, Copenhagen, Denmark
²¹Rigshospitalet, University of Copenhagen, Copenhagen N, Denmark
²²Department of Hematology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
²³The Danish Stem Cell Center (Danstem), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark
²⁴Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

Seok Jin Kim, MD, PhD¹, SangEun Yoon, MD, PhD^2*, Woorim Kang^3*, Mauricio Chalita^4*, Hong Hoe Koo, MD., PhD^5*, Dong-Wook Hyun^4*, Hyun Kim^4*, Junhun Cho, MD., PhD^6* and Won Seog Kim, MD^7*

¹Samsung Med. Ctr., Seoul, Korea, Republic of (South)
²Division of Hematology-Oncology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of (South)
³CJ Bioscience Inc, Seoul, Korea, Republic of (South)
⁴CJ Bioscience Inc, Seoul, KOR
⁵Sungkyunkwan Univ., School of Med. Samsung Medical Ctr., Seoul, KOR
⁶Department of Pathology and Translational Genomics, Samsung Medical Center, SEOUL, KOR
⁷Samsung Medical Center, Division of Hematology-Oncology, Department of Medicine, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of (South)

Mary B. Callanan, PhD^1*, Caroline Milin, MD, PhD^2,3,4*, Marie-Helene Delfau-Larue, MD, PhD^5*, Clément Bailly, MD, PhD^3*, Clémentine Sarkozy^6*, Catherine Thieblemont, MD⁷, Lucie Oberic, MD^8*, Emmanuel Gyan, MD, PhD⁹, Krimo Bouabdallah, MD^10*, Remy Gressin, MD^11*, Gandhi Damaj, MD, PhD^12*, Olivier Casasnovas, MD^13*, Vincent Ribrag, MD¹⁴, Samuel Griolet^15*, Barbara Burroni, MD^16*, Olivier Hermine, MD, PhD^17,18, Elizabeth A. Macintyre, MD, PhD¹⁹ and Steven Le Gouill, MD, PhD²⁰

¹Faculty of medicine, CHU de Dijon, Université de Bourgogne, INSERM 1231, Dijon, France
²Department of nuclear medicine, CHU Nantes, Nantes, France
³CRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France
⁴Department of Nuclear Medicine, University Hospital of Nantes, Nantes, France
⁵Hôpital Henri Mondor, Creteil, FRA
⁶Hematology Department, Institut Curie, Saint Cloud, France
⁷Hemato-Oncology, Hôpital Saint-Louis, APHP, University of Paris, Paris, France
⁸IUCT - Oncopole, Hematology Department, Toulouse, France
⁹CHU de Tours, Service d'Hématologie & Thérapie Cellulaire, Centre Hospitalier Universitaire, Tours, France
¹⁰Bordeaux university hospital, Haut-Leveque, Department of hematology, Bordeaux, France
¹¹CHU Grenoble, Grenoble, France
¹²CHU Caen, Caen, France
¹³François Mitterand Hospital, Dijon, FRA
¹⁴Département d'Innovation Thérapeutique et d'Essais Précoces (DITEP), Gustave Roussy Institute of Cancer, Villejuif, France
¹⁵LYSARC, Statistics, Pierre-Benite, Lyon, France
¹⁶Department of Pathology, Hôpital Cochin, Université de Paris, APHP, Paris, France
¹⁷Hematology, Necker Hospital, Greater Paris University Hospitals (AP-HP), Paris, France
¹⁸Institut Imagine - INSERM U1163, Paris, France
¹⁹Laboratory of Onco-Hematology, Necker Enfants-Malades Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Paris Cité, Paris, France, Paris, France
²⁰Institut Curie, Saint-Cloud, France

Sabrina Baaklini, PhD^1*, Alexandre Sarrabay^1*, Adrien Mazuel^1*, Bertrand Escaliere^1*, Chuang Dong^1*, Camille Barthelemy^1*, Laurine Gil^1*, Laila Dahbi^1*, Noushin Mossadegh-Keller, PhD^1*, Nathalie Van Acker^2*, Pauline Gravelle^3*, Jean-Marc Navarro^1*, Caroline Huber^1*, Romain Fenouil, PhD^1*, Romane Trombetta^1*, Marine Pujol^1*, Philippe Gaulard, MD, PhD^4*, Benjamin Riviere, MD^5*, Peggy Dartigues, MD^6*, Francesco Llamas Gutierrez, MD^7*, Celine Pangault^8*, Fabrice Jardin, MD, PhD^9*, François Lemonnier^10*, Gilles Salles, MD, PhD¹¹, Corinne Haioun, MD, PhD¹², Gabriel Brisou, MD, PhD^13*, Matthew E. Stokes^14*, Sahil Seth^14*, Maria Ortiz Estevez^15*, Camille Laurent, MD, PhD^16*, Lionel Spinelli, PhD^1*, Mark Kaplan, PhD^14*, C. Chris Huang, PhD^14*, Anita K. Gandhi, PhD¹⁷, Bertrand Nadel, PhD¹⁸, Sandrine Roulland, PharmD, PhD^1* and Pierre Milpied, PhD^1*

¹Aix Marseille Université, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France
²Institut Universitaire Cancer-Oncopole, CHU Toulouse, Centre de Recherches en Cancérologie de Toulouse, INSERM U1037, Toulouse, France
³INSERM UMR 1037-Cancer Research Center of Toulouse, TOULOUSE, France
⁴Pathology Department, Henri Mondor University Hospital, AP-HP, Créteil, France
⁵Pathology Department, Hôpital Gui De Chauliac, Montpellier, France
⁶Department of Pathology, Gustave Roussy, Villejuif, France
⁷Department of Pathology, CHU Pontchaillou, Rennes, France
⁸Pôle Biologie, CHU Rennes, Rennes, France
⁹Department of Hematology, Centre Henri Becquerel, Rouen, France
¹⁰Department of Hematology, Henri Mondor Hospital, CRETEIL, France
¹¹Lymphoma Service Chief, Memorial Sloan Kettering Cancer Center, New York, NY
¹²Lymphoid Malignancies Department, Henri Mondor University Hospital, AP-HP, Créteil, France
¹³Institut Paoli-Calmettes, Marseille, France
¹⁴Bristol Myers Squibb, Summit, NJ
¹⁵Bristol Myers Squibb, Sevilla, Spain
¹⁶Pathology Department, Institut Universitaire du Cancer , Oncopole, Toulouse, France
¹⁷Hematology, Translational Medicine, Bristol Myers Squibb, Summit, NJ
¹⁸Centre D'Immunologie De Marseille-Luminy, Marseilles, France

Upasana Ray^1*, Richard J. Jones, PhD^1,2* and Robert Z. Orlowski, MD, PhD^1,3

¹Department of Lymphoma & Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
²Asylia Therapeutics, Inc., Houston, TX
³Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX

Brian H. Santich, PhD^1*, Linlin Wang, PhD^1*, Azeezat Abdulsalam, MS^1*, Mallika Vadlamudi, PhD^1*, Nico Liebenberg, PhD^2*, Amadou Ouattara, MSChE^1*, Kandarp Jani, MS^1*, Johannes Nagel, PhD^2*, Norman LaFrance, MD^1* and Charlotte A. Russell, MD³

¹Science and Translational Medicine, Y-mAbs Therapeutics Inc, New York, NY
²CMC Development, Y-mAbs A/S, Hørsholm, Denmark
³Clinical Development, Y-mAbs Therapeutics A/S, Hørsholm, Denmark

Tina Bagratuni, PhD^1*, Christos Vlachos, PhD^2*, Maria Sakkou, PhD^3*, Ioannis Kollias^1*, Ourania Theologi^1*, Nefeli Mavrianou Koutsoukou^4*, Christine-Ivy Liacos, MS^2*, Kostantina Taouxi^4*, Alexandra Papadimou^4*, Katerina Chrisostomidou^4*, Despina Fotiou, MD^4*, Maria Gavriatopoulou^4*, Evangelos Terpos, MD, PhD⁵, Efstathios Kastritis, MD, PhD^4* and Meletios-Athanasios Dimopoulos^4,6,7

¹Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece
²National and Kapodistrian University of Athens, Athens, Greece
³National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
⁴Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
⁵Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Drosia, Attiki, Greece
⁶University of Athens School of Medicine, Athens, Greece
⁷General Hospital of Athens-Alexandra, Llisia, Greece

Miro Nylén^1,2*, Leo Meriranta, MD^3,4*, Emil Hiitola, MSc^1,2*, Maare Arffman, MSc^3,4*, Harald Holte, MD, PhD⁵, Judit Mészáros Joergensen, MD, PhD^6*, Peter Brown, MD, PhD^7*, Sirkku Jyrkkiö, MD, PhD^8*, Mats Jerkeman, MD, PhD^9,10, Øystein Fluge, MD, PhD^11*, Magnus Björkholm, MD, PhD^12*, Lars Møller Pedersen, MD, PhD^13,14*, Mikael Eriksson, MD, PhD^9,10*, Satu Mustjoki, MD, PhD^1,2, Sirpa Leppä, MD, PhD^3,4 and Mikko Myllymäki, MD, PhD^1,2

¹Translational Immunology Research Program and Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland
²Hematology Research Unit Helsinki, University of Helsinki and Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland
³Department of Oncology, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland
⁴Applied Tumor Genomics Research Program and Department of Oncology, University of Helsinki, Helsinki, Finland
⁵Department of Oncology, Oslo University Hospital and KG Jebsen Centre for B cell malignancies, Oslo, Norway
⁶Department of Hematology, Aarhus University Hospital, Aarhus, Denmark
⁷Department of Hematology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
⁸Department of Oncology, Turku University Hospital, Turku, Finland
⁹Skane University Hospital, Lund, Sweden
¹⁰Lund University, Lund, Sweden
¹¹Department of Oncology, Haukeland University Hospital, Bergen, Norway
¹²Department of Medicine, Karolinska University Hospital, Stockholm, Sweden
¹³Department of Hematology, Zealand University Hospital, Roskilde, Denmark
¹⁴Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

Johnvesly Basappa, PhD^1*, Shengchun Wang, PhD^1*, Cosimo Lobello, PhD^2*, David Rushmore, BS^2*, Olga Melnikov^3*, Neil Sen, BS^4*, Vinay Mallikarjuna, MBBS^5*, Priyanka Jain, BS^6*, Pin Lu, MD, Ph.D.^1*, Y. Lynn Wang, MD, PhD¹, Kathy Cai, MD PhD^2*, Reza Nejati, MD², Aaron Goldman, PhD^7* and Mariusz Wasik, MD^1*

¹Fox Chase Cancer Center, Philadelphia, PA
²Fox Chase Cancer Center, PHILADELPHIA, PA
³Eurofin Laboratories, Lancaster, PA
⁴Philadelphia College of Osteopathic Medicine,, Philadelphia, PA
⁵Cincinnati Children's Hospital Medical Center, Cincinnati, Cincinatti, OH
⁶Yale university, New Haven
⁷Wistar Institute, Philadelphia, PA

Eleni Kalafati^1*, Kostantina Taouxi^2*, Ourania Theologi^1*, Nefeli Mavrianou Koutsoukou^2*, Ioannis Kollias^1*, Christine-Ivy Liacos, MS^2*, Alexandra Papadimou^2*, Katerina Chrisostomidou^2*, Maria Gavriatopoulou^2*, Meletios Dimopoulos, MD², Evangelos Terpos, MD, PhD³, Nicholas P. Anagnou, MD, PhD^4*, Efstathios Kastritis, MD^2* and Tina Bagratuni, PhD^1*

¹Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Athens, Greece
²Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
³Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Drosia, Attiki, Greece
⁴Laboratory of Cell and Gene Therapy, National and Kapodistrian University of Athens, Athens, Greece

Elliot O. Eton, BS^1,2,3*, Saravanan Ganesan, PhD^2,3, Rebecca M. Murray, BS^2,3*, Benjamin H. Durham, MD⁴, Jae H. Park, MD⁵, Omar Abdel-Wahab, MD^6,7 and Dan A. Landau, MD, PhD^2,3*

¹Tri-Institutional MD-PhD Program, Weill Cornell Medicine, Rockefeller University, Memorial Sloan Kettering Cancer Center, New York, NY
²Division of Hematology and Medical Oncology and Meyer Cancer Center, Department of Medicine, Weill Cornell Medicine, New York, NY
³New York Genome Center, New York, NY
⁴Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁵Cell Therapy Service and Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁶Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁷Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY

Xiaodan Luo^1*, Wenpu Lai^2*, Jianbo Liu^1*, Boyun Shi^1*, Jianli Tang^1*, Danyun Yuan^1*, Ao Chen^1*, Jiayu Huang^1*, Huo Tan^1* and Runhui Zheng^1*

¹The Fifth Affiliated Hospital of Guangzhou Medical University, Guangzhou, China
²The First Affiliated Hospital of Jinan University, Guangzhou, China

Davidson Zhao^1,2, Victoria Shelton, MSc^1*, Inna Gong, MD, PhD³, Juan Rangel-Patiño, MD¹, Ting Liu, PhD^1*, Michael Hong^1*, Vanessa Murad, MD^4*, Ur Metser^4*, Anca Prica, MD³, Vishal Kukreti, MD, MSc⁵, Sita Bhella, MD^3*, Abi Vijenthira, MD, MS³, Michael Crump, MD^3*, John Kuruvilla, MD, FRCPC³, Bernard Lam, PhD^6* and Robert Kridel, MD, PhD³

¹Princess Margaret Cancer Centre - University Health Network, Toronto, ON, Canada
²Department of Medical Biophysics - University of Toronto, Toronto, Canada
³Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre - University Health Network, Toronto, ON, Canada
⁴Department of Medical Imaging, Princess Margaret Cancer Centre - University Health Network, Toronto, ON, Canada
⁵Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre, Toronto, ON, Canada
⁶Ontario Institute for Cancer Research, Toronto, Canada

Benjamin Diamond, MD¹, Dhanvantri Chahar, PhD^2*, Michael D. Jain, MD, PhD³, Alexandra Maria Poos, PhD^4*, Michael Durante, MD, PhD^2*, Bachisio Ziccheddu^1*, Marcella Kaddoura, MD⁵, Marios Papadimitriou, MD^1*, Kylee H Maclachlan, PhD, BSc, FRACP, FRCPA⁶, Tomas Jelinek⁷, Faith E Davies, MD⁸, Nicholas B Figura, MD^9*, Gareth Morgan, M.D., Ph.D.^8*, Elias K. Mai, MD^4*, Hartmut Goldschmidt, MD¹⁰, Katja C. Weisel, MD¹¹, Roland Fenk, MD, PhD^12*, Saad Z. Usmani, MD⁶, Ola Landgren¹, Frederick Locke, MD¹³, Marc S. Raab^4*, Jonathan H. Schatz, MD¹⁴, Niels Weinhold, PhD^4* and Francesco Maura, MD¹

¹Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
²University of Miami Miller School of Medicine, Miami, FL
³Department of Blood and Marrow Transplantation and Cellular Immunotherapy, Moffitt Cancer Center, Tampa, FL
⁴Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Heidelberg, Germany
⁵Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Dearborn, MI
⁶Myeloma Service, Division of Hematologic Oncology, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
⁷Department of Hematooncology, University Hospital Ostrava, Ostrava, Ostrava-Mesto, Czech Republic
⁸NYU Perlmutter Cancer Center, NYU Grossman School of Medicine, New York, NY
⁹Department of Radiation Oncology, Moffitt Cancer Center, Tamps, FL
¹⁰Heidelberg Myeloma Center, Heidelberg, Germany
¹¹Department of Oncology, Hematology and BMT, University Medical Center of Hamburg-Eppendorf, Hamburg, Germany
¹²Department of Haematology, Oncology, and Clinical Immunology, University Hospital Düsseldorf, Düsseldorf, Germany
¹³Moffitt Cancer Center, Tampa, FL
¹⁴University of Miami, Miami, FL