Anand Ashwin Patel, MD¹, Adam S. Duvall, MD¹, Caner Saygin, MD¹, Howard Weiner^2*, Emily Dworkin, PharmD^3*, Afsheen Noorani, ANP^2*, Jamie Matthews, FNP-BC^4*, Rafael Madero Marroquin, MD⁵, Michael W Drazer, MD, PhD⁶, Mariam T. Nawas, MD², Gregory W Roloff, MD², Satyajit Kosuri, MD², Michael J. Thirman, MD⁷, Richard A. Larson, MD¹, Olatoyosi Odenike, MD¹, Theodore Karrison, PhD^2* and Wendy Stock, MD¹

¹Department of Medicine, Section of Hematology/Oncology, University of Chicago, Chicago, IL
²University of Chicago, Chicago, IL
³Department of Pharmacy, University of Chicago, Chicago, IL
⁴Section of Hematology and Oncology, University of Chicago Medical Center, Chicago, IL
⁵Section of Hematology/Oncology, Department of Medicine, University of Chicago, Chicago, IL
⁶Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL
⁷Section of Hematology/Oncology, The University of Chicago, Chicago, IL, Chicago

Nicolas Lecornec^1*, Florence Rabian, MD^2*, Marie-Emilie Dourthe, MD, PhD^1,3*, Florian Chevillon, MD^2*, Karima Yakouben, MD^1*, Delphine Chaillou^1*, Sophie Caillat-Zucman, MD^4*, Alexis Cuffel^5*, Emmanuelle Lesprit, MD^6*, Anne Arnould^6*, Jérome Naudin^7*, Julie Roupret-Serzec^1*, Nathalie Parquet, MD^8*, Anne Brignier, MD^9*, Valerie Guerin-El Khourouj^10*, Elodie Lainey, PhD, PharmD^11*, Aurélie Caye-Eude^12*, Chloe Arfeuille^12*, Emmanuelle Clappier, Pharm.D., Ph.D.^9,13*, Rathana Kim, Pharm.D.^14*, Stéphanie Mathis, PharmD^15*, Marie-Laure Chaix^16*, Elie Azoulay^17*, Jean-Hugues Dalle, MD, PHD¹⁸, Isabelle Madelaine^19*, Jerome Larghero^20*, André Baruchel, MD, PhD²¹ and Nicolas Boissel, MD, PhD^22,23

¹Department of Pediatric Hematology and Immunology, University Hospital Robert Debré, Assistance Publique des Hôpitaux de Paris (APHP), Paris, France
²Hematology Adolescents and Young Adult Unit, Saint-Louis Hospital, APHP, Paris, France, Paris, France
³Laboratory of Onco-Hematology, Necker Children's Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France
⁴Inserm U976 HIPI, Hôpital Saint Louis, Paris, France
⁵Assistance Publique Hôpitaux De Paris, Saint Louis Hospital, Immunology D, Paris, France
⁶Robert Debré Hospital, EFS, Paris, France
⁷HôPital Robert Debré, APHP, Paris, FRA
⁸Apheresis, Saint-Louis Hospital, APHP, Paris, France
⁹Saint Louis Hospital, Paris, France
¹⁰Laboratory of Immunology, Hôpital Universitaire Robert Debré́, AP-HP and Université Paris Cité, Paris, France
¹¹Robert Debre Hospital, Paris, FRA
¹²Department of Genetics, University Hospital Robert Debré, Assistance Publique Des Hôpitaux, Paris, France
¹³INSERM U944/CNRS UMR7212, Institut de Recherche Saint- Louis, Université Paris Cité, Paris, France
¹⁴Assistance Publique Des Hopitaux De Paris (AP-HP) - Universite Paris Descartes -, Paris, Ile-de-France, FRA
¹⁵Laboratory of Hematology and Flow cytometry, Saint Louis Hospital, APHP, Paris, France
¹⁶Laboratory of Virology, Saint Louis Hospital, APHP, Paris, France
¹⁷Médecine Intensive Réanimation, Hôpital Saint Louis, AP-HP, Paris, France
¹⁸Department of Pediatric Hematology and Immunology, Robert-Debré Academic Hospital ,, Assistance Publique des Hôpitaux de Paris (APHP), Paris, France
¹⁹Pharmacy department, Saint-Louis Hospital, APHP, Paris, France
²⁰Cell Therapy Unit, Saint-Louis Hospital, APHP, Paris, France
²¹Department of Pediatric Hematology and Immunology,, University Hospital Robert Debré, Assistance Publique des Hôpitaux de Paris (APHP), Paris, France
²²Institut Universitaire d'Hématologie, EA-3518, University Hospital Saint-Louis, Assistance Publique des Hôpitaux de Paris (APHP), Paris, France
²³Hematology Adolescents and Young Adult Unit, Saint-Louis Hospital, APHP, Paris, France, Paris Cedex 10, Paris, France

Marie Balsat, MD^1*, Corentin Orvain^2*, Jean-François Benoist^3*, Nicolas De Roux^4*, Thibaut Leguay, MD^5*, Françoise Huguet, MD^6*, Patrice Chevallier, MD, PhD⁷, Cendrine Josson^8*, Christine Bain-Wendlinger^8*, Yosr Hicheri, MD^9*, Anne Thiebaut, MD^10*, Martine Escoffre-Barbe, MD^11*, Thomas Cluzeau, MD, PhD¹², Florence Pasquier, MD, PhD^13*, Ana Berceanu, MD^14*, Florence Van Obbergh^15*, Jamilé Frayfer^16*, Gaëlle Guillerm, MD^17*, Victoria Cacheux^18*, Isabelle Plantier, MD^19*, Laurence Sanhes, MD^20*, Chantal Himberlin^21*, Jacques Vargaftig, MD, PhD^22*, Sabine Tricot^23*, Yves Chalandon²⁴, Carlos Graux^25*, Véronique Lheritier^26*, Hervé Dombret, MD, PhD²⁷, Hunault-Berger Mathilde^28* and Nicolas Boissel, MD, PhD²⁹

¹Clinical Hematology Department, Hospices Civils de Lyon, Lyon Sud Hospital, Pierre-Bénite, France, Lyon, France
²Maladies du Sang, CHU d’Angers, Angers, France
³Biochemistry Department, Hôpital Universitaire Necker Enfants Malades, Paris, France
⁴Laboratoire de Biochimie-Hormonologie, Hôpital Robert Debré, Paris, France
⁵Hematology, CHU Bordeaux, Hôpital du Haut-Lévêque, Pessac, France
⁶Hematology Department, Institut Universitaire du Cancer-Oncopole & CHU de Toulouse, Toulouse, France
⁷Hematology Department, Nantes University Hospital, Nantes, France
⁸KCAS Bio SAS, Lyon, France
⁹Department of Hematology, Institut Paoli-Calmettes, Marseille, France
¹⁰CHU Grenoble, Grenoble, France
¹¹Hematology department, Hôpital de Pontchaillou, Rennes, France
¹²Department for Clinical Hematology, Nice University Hospital, Nice, France
¹³Gustave Roussy, VILLEJUIF, France
¹⁴Department of Clinical Hematology, CHU de Besançon, Besançon, France
¹⁵Centre Hospitalier de Jolimont, La Louviere, Belgium
¹⁶Hematology Department, Grand Hôpital de l'Est Francilien, Meaux, France
¹⁷Service d'hématologie, Hôpital Morvan, CHRU Brest, Brest, France
¹⁸CHU Estaing, Clermont Ferrand, France
¹⁹Hopital Victor Provo, Roubaix, France
²⁰Centre Hospitalier Perpignan, Perpignan, France
²¹Hôpital Robert Debré, Reims, France
²²Institut Curie - Site Saint Cloud, Saint-Cloud, France
²³Centre Hospitalier De Valenciennes, Valenciennes, France
²⁴Division of Oncology and Hematology, Univ. Hospital of Geneva, Geneva, Switzerland
²⁵CHU UCL Namur - site Godinne, Yvoir, Belgium
²⁶Service d’Hématologie Coordination GRAALL, HCL, Hôpital Lyon Sud, Pierre Bénite, France
²⁷Hôpital St Louis, Paris, France
²⁸CHU Angers, Angers, France
²⁹Hôpital Saint-Louis, Paris, France

Julie Ma, MD¹, Annie Luong^2*, Andrew Doan, MD^1,3*, Tsen Yin Lin^2*, Anh Duong^2*, Miguel Villa^1* and Chintan Parekh, MD^1,3

¹Cancer and Blood Disease Institute, Children's Hospital Los Angeles, Los Angeles, CA
²The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, CA
³University of Southern California Keck School of Medicine, Los Angeles, CA

Anjali Cremer^1,2,3*, Maher Hanoun, MD, PhD^4*, Ralph Wäsch⁵, Simon Raffel, MD^6*, Klaus Wethmar, MD^7*, Andreas Viardot, MD, PhD⁸, Walter Fiedler, MD⁹, Knut Wendelin^10*, Lore Marretta^11*, Wolfram Jung^12*, Roland Schroers, MD^13*, Vladan Vucinic, MD^14*, Monika Brüggemann, MD^15*, Stefan Schwartz, MD^16*, Hubert Serve, MD^2,3,17 and Nicola Goekbuget, MD¹⁸

¹Department of Medicine II, Hematology/Oncology, Goethe University Hospital, Frankfurt, Germany
²German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), Frankfurt, Germany
³Frankfurt Cancer Institute (FCI), Frankfurt, Germany
⁴Department of Hematology and Stem Cell Transplantation, University Hospital Essen, Essen, Germany
⁵Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, Albert Ludwigs University (ALU), Freiburg, Germany, Freiburg, Germany, Freiburg, Germany
⁶Department of Medicine V, Universität Heidelberg, Heidelberg, Germany
⁷Department of Medicine A (Hematology, Hemostaseology, Oncology, Pneumology), University Hospital Muenster, Muenster, Germany
⁸Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
⁹Department of Oncology, Hematology and Bone Marrow Transplantation with Division of Pneumology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
¹⁰Med Clinic 5, Klinikum Nürnberg, Nuernberg, Germany
¹¹Department of Internal Medicine, Vivantes Klinikum Neukölln, Berlin, Germany
¹²Department of Hematology and Medical Oncology, University Hospital Goettingen, Goettingen, Germany
¹³Knappschaftskrankenhaus Bochum, University Hospital Bochum, Bochum, Germany
¹⁴University Hospital Leipzig, Leipzig, Germany
¹⁵University Medical Center Schleswig-Holstein, University Cancer Center Schleswig-Holstein, Kiel, Germany
¹⁶Department of Hematology, Oncology and Cancer Immunology (Campus Benjamin Franklin), Charité – Universitätsmedizin Berlin, corporate member of Freie Universität and Humboldt-Universität zu Berlin, Berlin, Germany
¹⁷Department of Medicine, Hematology/Oncology, Goethe-University Frankfurt, University Hospital, Frankfurt am Main, Germany
¹⁸Department of Medicine, Hematology/Oncology, Goethe University Frankfurt, University Hospital, Frankfurt, Germany

Anna Torrent, MD^1*, Mireia Morgades^2*, Susana Barrera^3*, Jordi Ribera^2*, Beatriz Soriano^4*, Pau Montesinos, PhD, MD^5,6*, Eulàlia Genescà^2*, José González-Campos, M.D.^7*, Pere Barba, MD⁸, Jordi Esteve, MD, PhD^9,10, Marta Sitges^11*, Maria Paz Queipo De Llano^12*, Carmen Botella^13*, Clara Maluquer Artigal, MD^14*, Irene García-Cadenas, MD^15*, Marisa Calabuig^16*, Alberto Hernández-Sánchez^17*, Laura Torres, MD^18*, Isabel Granada, MD^2*, Jesus Maria Hernandez Rivas, MD^19,20, Alberto Orfao, MD, PhD^4* and Josep-Maria Ribera, MD, PhD^21,22

¹Hematology department, Institut Català D'oncologia-Hospital Germans Trias I Pujol. Josep Carrera, Badalona, Spain
²ICO-Hospital Germans Trias i Pujol, Institut de Recerca contra la Leucèmia Josep Carreras (IJC), Universitat Autònoma de Barcelona, Badalona, Spain
³Translational and Clinical Research Program, Cancer Research Center (IBMCC, CSIC – University of Salamanca); Cytometry Service, NUCLEUS; Department of Medicine, University of Salamanca (Universidad de Salamanca), Salamanca, Spain. IBSAL (Salamanca, Spain), Salamanca, Spain
⁴Cancer Research Center (IBMCC-CSIC/USAL-IBSAL), Cytometry Service (NUCLEUS) and Department of Medicine, University of Salamanca, Salamanca, Spain
⁵Hematology, Hospital Universitari I Politécnic La Fe and Programa Español de Tratamientos en Hematología (PETHEMA) Group, Valencia, Spain
⁶Department of Hematology, Instituto de Investigación Sanitaria La Fe, Valencia, Spain
⁷Hematology Department, Hospital Universitario Virgen del Rocío, Sevilla, Spain, Sevilla, Spain
⁸Vall d’Hebron Institute of Oncology (VHIO), Department of Hematology, University Hospital Vall d'Hebron, Universitat Autònoma of Barcelona (UAB), Barcelona, Spain
⁹Fundació de Recerca Clínic Barcelona-Institut d'Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS), Barcelona, Spain
¹⁰Hematology Department, Hospital Clínic de Barcelona, Barcelona, Spain
¹¹Hematology Department, Institut Català d`Oncologia, Girona, ESP
¹²Hematology Department Hospital Universitario Virgen de la Victoria, Málaga, Spain, Malaga, ESP
¹³Hospital General Universitario de Alicante, Alicante, Spain
¹⁴Hematology Department. Institut Català d’Oncologia, Hospital Duran i Reynals. Institut d’Investigació Biomèdica de Bellvitge (IDIBELL), L’Hospitalet de Llobregat, Barcelona, Spain
¹⁵Hematology Service, Hospital Santa Creu i Sant Pau, Barcelona, Spain
¹⁶Hematology department, Hospital Clínico de Valencia. Instituto de Investigación Sanitaria INCLIVA de Valencia, Valencia, Spain., Valencia, Spain
¹⁷Departmente of Hematology, University Hospital Salamanca, Barcelona, Spain
¹⁸Hematology department, Hospital Universitario la Fe de Valencia, Valencia, Spain., Valencia, Spain
¹⁹Servicio de Hematología, Hospital Universita­rio de Salamanca, Universidad de Salamanca, Salamanca, Spain
²⁰Department of Medicine, University of Salamanca, Institute of Biomedical Research of Salamanca (IBSAL), University of Salamanca – Cancer Research Center of Salamanca (IBMCC, USAL-CSIG), Salamanca, Spain
²¹Ico-Hospital Universitari Germans Trias Y Pujol, Badalona, Barcelona, ESP
²²Josep Carreras Leukemia Research Institute, Badalona, Barcelona, Spain., Badalona, Spain

Kate D. Westmoreland, MD^1,2*, Zachary L Taylor, PhD^3,4*, Tamara P. Miller, MD^5,6, Ashley Chavana^7*, Karen R Rabin, MD, PhD^8,9, Austin L Brown, PhD, MPH¹⁰, Melanie Brooke Bernhardt, MS, PharmD^11*, Eric S. Schafer, MD, MHS^8,9, Maureen M. O'Brien, MD¹², Sharon M. Castellino, MD, MSc^5,13 and Laura B. Ramsey, PhD^3,4*

¹Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC
²Department of Pediatrics, Division of Pediatric Hematology-Oncology, University of North Carolina, Chapel Hill, NC
³Cancer and Blood Disease Institute, Division of Translational and Clinical Pharmacology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
⁴Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH
⁵Aflac Cancer and Blood Disorders Center, Children's Healthcare of Atlanta, Atlanta, GA
⁶Department of Pediatrics, Division of Hematology, Oncology, and Bone Marrow Transplant, Emory University School of Medicine, Decatur, GA
⁷Baylor College of Medicine, Houston, TX
⁸Department of Pediatrics, Division of Pediatric Hematology/Oncology, Baylor College of Medicine, Houston, TX
⁹Cancer Center and Division of Pediatric Hematology/Oncology, Texas Children's Hospital, Houston, TX
¹⁰Department of Pediatrics, Baylor College of Medicine, Houston, TX
¹¹Department of Pharmacy and Pharmaceutical Science, St. Jude Children’s Research Hospital, Memphis, TN
¹²Colorado Children's Hospital and the University of Colorado School of Medicine, Aurora, CO
¹³Department of Pediatrics, Division of Hematology, Oncology, and Bone Marrow Transplant, Emory University School of Medicine, Atlanta, GA

Daniel Nguyen, MD, PhD¹, Hagop Kantarjian, MD², Nicholas J. Short, MD², Nitin Jain, MD², Fadi G. Haddad, MD², Musa Yilmaz, MD², Alessandra Ferrajoli, MD², Tapan M. Kadia, MD², Yesid Alvarado Valero, MD², Abhishek Maiti, MBBS³, Marianne Zoghbi^2*, Jayastu Senapati, MD, DM, MBBS², Rebecca Garris^2*, Min Zhao^4*, Marina Konopleva, MD⁵, Farhad Ravandi, MBBS⁶ and Elias Jabbour, MD⁷

¹University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
³Department of Leukemia, The University of Texas Health Science Center At Houston, Houston, TX
⁴The University of Texas MD Anderson Cancer Center, Houston, TX
⁵Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, NY
⁶Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
⁷Department of Leukemia, University of Texas M.D. Anderson Cancer Ctr., Houston, TX

Elias Jabbour, MD¹, Gerhard Zugmaier, M.D., Ph.D², Pilar Martinez Sanchez, M.D.^3*, Jose J. Rifon, M.D.^4*, Vaibhav Agrawal, M.D.⁵, Ryan D Cassaday, M.D.^6,7*, Thomas Cluzeau, MD, PhD⁸, Françoise Huguet, MD^9*, Vladan Vucinic, MD^10*, Boris Böll, MD^11*, Anita W. Rijneveld, MD, PhD¹², Mar Tormo, MD¹³, Maher Abdul-Hay, MD^14*, Paul R Gordon, M.D.^15*, Alessandro Rambaldi¹⁶ and Hagop M. Kantarjian, MD¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Amgen Research Munich, Munich, Germany
³Hematology Department, Hospital Universitario 12 de Octubre, Madrid, Spain
⁴Hematology and Hemotherapy Department, Clínica Universidad de Navarra, Pamplona, Spain
⁵Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA
⁶Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA
⁷Department of Medicine, University of Washington School of Medicine, Seattle, WA
⁸Nice University Hospital, Nice, France
⁹Hematology Department, Institut Universitaire du Cancer-Oncopole & CHU de Toulouse, Toulouse, France
¹⁰Department for Hematology, Cell Therapy, Hemostaseology and Infectious Diseases, University of Leipzig, Leipzig, Saxony, Germany
¹¹Department I of Internal Medicine and German Hodgkin Study Group (GHSG), University Hospital of Cologne; equal contribution, Cologne, Germany
¹²Department of Hematology, Erasmus MC Cancer Institute, University Medical Center Rotterdam, Rotterdam, Netherlands
¹³Department of Hematology and Medical Oncology,, Hospital Clínico Universitario de Valencia. INCLIVA Biomedical Research Institute, Valencia, Spain
¹⁴Blood and Marrow Transplantation and Cellular Therapy, Laura and Issac Perlmutter Cancer Center at NYU Langone Health, New York, NY
¹⁵Amgen Inc., Thousand Oaks, CA
¹⁶Department of Oncology and Hematology, University of Milan and Azienda Socio-Sanitaria Territoriale Papa Giovanni XXIII, Bergamo, Italy

Jayastu Senapati, MD, DM, MBBS¹, Elias Jabbour, MD², Nitin Jain, MD¹, Fadi G. Haddad, MD¹, Guillermo Garcia-Manero, MD¹, Naval Daver, MD³, Tapan M. Kadia, MD¹, Farhad Ravandi, MBBS⁴, Koji Sasaki, MD¹, Courtney D. DiNardo, MD, MSc⁵, Koichi Takahashi, MD, PhD¹, Rebecca Garris^1*, Jovitta Jacob, RN^6*, Yesid Alvarado Valero, MD¹, Guillermo Montalban-Bravo, MD¹, Nicholas J. Short, MD¹ and Hagop Kantarjian, MD¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, University of Texas M.D. Anderson Cancer Ctr., Houston, TX
³MD Anderson Cancer Center, Houston, TX
⁴Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
⁵Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
⁶The University of Texas MD Anderson Cancer Center, Houston, TX

Jayastu Senapati, MD, DM, MBBS¹, Elias Jabbour, MD², Nicholas J. Short, MD¹, Nitin Jain, MD¹, Fadi G. Haddad, MD¹, Tapan M. Kadia, MD¹, Koji Sasaki, MD¹, Yesid Alvarado Valero, MD¹, Koichi Takahashi, MD, PhD¹, Courtney D. DiNardo, MD, MSc³, Naval Daver, MD⁴, Guillermo Garcia-Manero, MD¹, Farhad Ravandi, MBBS⁵, Jovitta Jacob, RN^6*, Rebecca Garris^1* and Hagop Kantarjian, MD¹

¹Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
²Department of Leukemia, University of Texas M.D. Anderson Cancer Ctr., Houston, TX
³Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
⁴MD Anderson Cancer Center, Houston, TX
⁵Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
⁶The University of Texas MD Anderson Cancer Center, Houston, TX

Jingliao Zhang, MD¹, Junxia Wang^1*, Huanshan Guo, MD^2*, Tianfeng Liu^3*, Xiaoyan Zhang^1*, Ranran Zhang^1*, Min Ruan, MD^1*, Lixian Chang, PhD^4*, Xiaoming Liu, MD^1*, Yuanyuan Ren, MD^1*, Xia Chen^5*, Hengbang Wang, PhD^6*, Zi Chen, MD, PhD^6*, Yingchi Zhang^4*, Yumei Chen^1*, Li Zhang^4*, Ye Guo^1*, Fang Liu, MD^7*, Xiaojuan Chen, MD^8*, Yao Zou^9*, Wenyu Yang, MD^7*, Yifan Zhai, MD, PhD^2,6,10 and Xiaofan Zhu, MD^1*

¹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin, China
²Guangzhou Healthquest Pharma Co., Ltd., Guangzhou, China
³State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences&Peking Union Medical College, Tianjin, China
⁴State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, CAMS & PUMC, Tianjin, China
⁵Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, Tianjin, China
⁶Ascentage Pharma (Suzhou) Co., Ltd., Suzhou, China
⁷Department of Pediatric Hematology and Oncology, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology& Blood Diseases Hospital, Chinese Academy of Medical Sciences& Peking Union Medical College, Tianjin, China
⁸Department of Pediatric Hematology and Oncology, State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences&Peking Union Medical College, Tianjin, China
⁹State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, National Clinical Research Center for Blood Diseases, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China
¹⁰Ascentage Pharma Group Inc., Rockville, MD

Marko Kavcic, MD, PhD^1*, Volkan Hazar, MD, MsC^2*, Anna Mohás, MD^3*, Veronika Enzsöl, MD^4*, Andrea Reyes, MD^5*, Boryana Avramova, MD PhD^6*, Tomaz Prelog, MD, PhD^1*, Mirella Ampatzidou, MD, PhD^7*, Koray Yalcin, MD^8*, Monica Makiya^9*, Sophia Polychronopoulou, MD, PhD^7*, Juan Tordecilla, MD^10*, Janez Jazbec, MD, PhD^1* and Daniel J Erdelyi, MD, PhD^3*

¹University Medical Centre, Ljubljana, SVN
²Memorial Health Group Medstar Yildiz Hospital, Antalya, Turkey
³Pediatric Center, Semmelweis University, Budapest, Hungary
⁴Heim Pál Children Hospital, Budapest, Hungary
⁵Hospital Robert de Rio, Santiago, Chile
⁶University Hospital “Tsaritsa Johanna-ISUL”, Sofia, Bulgaria
⁷Department of Pediatric Hematology Oncology, Aghia Sophia Children’s Hospital, Athens, Greece
⁸Bahcesehir University Medical Park Göztepe Hospital, Istanbul, Turkey
⁹Hospital Italiano de Buenos Aires, Buenos Aires, CH, ARG
¹⁰Clinica Santa Maria, Santiago, Chile

Omali Pitiyarachchi, MBBS, BSc, FRACP^1*, Madeleine T King, PhD^2*, Shane Gangatharan, MBBS, FRACP, FRCPA^3*, Michael Osborn, MBBS, FRACP, FRCPA^4*, Ashley P Ng, PhD, MBBS, FRACP, FRCPA^5*, Shaun Fleming, MBBS, FRACP, FRACPA^6*, Pasquale Fedele, MBBS, PhD^7*, Toby N Trahair, BSc(Med) hons, MBBS, PhD, FRACP^8*, John Casey, MBBS, BPharm(hons), FRACP, FRCPA, MHM^9*, Sally Mapp, MD^10*, Carol CY Cheung, PhD, FRACP, FRCPA, MBBS¹¹, Tasman Armytage, MBBS, BSc, FRACP, FRCPA^12*, Philip McCloud, PhD^13*, Peter Button^13*, Leesa Rowley^14*, Stephen Robert Larsen, MBBS PhD FRACP FRCPA¹⁵, Peter Presgrave, MBBS¹⁶, John Kwan, MBBS, FRACP, FRCPA^17*, Samuel Bennett, MBBS, FRACP, FRCPA^18*, Chun Yew Fong, MBBS, FRACP, FRCPA, PhD^19*, Luciano Dalla-Pozza, MD²⁰ and Matthew Greenwood, MBBS, FRACP, FRCPA²¹

¹School of Biomedical Sciences, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia
²The University of Sydney, Sydney, Australia
³Fiona Stanley Hospital, Murdoch, AUS
⁴Royal Adelaide Hospital, Adelaide, Australia
⁵Peter MacCallum Cancer Centre, Melbourne, Australia
⁶Department of Malignant Haematology & Stem Cell Transplantation, The Alfred Hospital, Melbourne, VIC, Australia
⁷Monash Hospital, Melbourne, Australia
⁸Paediatric Haematology & Oncology, Kids Cancer Center, Sydney Children's Hospital, Kensington, NSW, Australia
⁹The Townsville Hospital, Townsville, Australia
¹⁰Princess Alexandra Hospital, Brisbane, Australia
¹¹Prince of Wales Hospital, Randwick, Australia
¹²Gosford Hospital, Gosford, Australia
¹³McCloud Consulting Group, Sydney, Australia
¹⁴Australasian Leukaemia & Lymphoma Group, Richmond, AUS
¹⁵Royal Prince Alfred Hospital, Camperdown, Australia
¹⁶Wollongong Hospital, Wollongong, Australia
¹⁷Westmead Hospital, Westmead, NSW, Australia
¹⁸Canberra Hospital, Garren, Australia
¹⁹Department of Hematology, Austin Health, Heidelberg, VIC, Australia
²⁰The Children's Hospital at Westmead, Westmead, Australia
²¹Royal North Shore Hospital, Sydney, NSW, Australia

Clarissa Garcia¹, Kaylyn Lyons, MD^1*, Tian Liu^2*, Ilaria Iacobucci, PhD³, Amanda Novak, BS^1*, Amy Argabright^4*, Alexis Donnelly^1*, Julian Grandvallet Contreras, BS^2*, Huimin Geng, PhD^5*, Sabrina Smith⁶, Xin Zhou, PhD^7*, Markus Müschen, MD⁸, John Edgar Dick⁶, Julie R Haines, PhD^4*, Angelo D'Alessandro, PhD⁹, Charles G. Mullighan, MBBS, MSc, MD¹⁰, Tzu Phang, PhD^1*, M. Eric Kohler, MD, Ph.D¹¹ and Matthew Witkowski, PhD¹

¹Department of Pediatrics, University of Colorado Anschutz Medical Campus, Aurora, CO
²Department of Pediatrics, Section of Hematology/Oncology/BMT, University of Colorado Anschutz Medical Campus, Aurora, CO
³St. Jude Children's Research Hospital, Memphis, TN
⁴Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO
⁵Department of Laboratory Medicine, University of California San Francisco Helen Diller Family Comprehensive Cancer Center, San Francisco, CA
⁶Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada
⁷Department of Computational Biology, St Jude Childrens Research Hospital, Memphis, TN
⁸Center of Molecular and Cellular Oncology, Yale University, New Haven, CT
⁹Department of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus, Aurora, CO
¹⁰Department of Pathology, St. Jude Children's Research Hospital, Memphis, TN
¹¹Department of Pediatrics- Hematology, Oncology, and Bone Marrow Transplant, University of Colorado Anschutz Medical Campus, Aurora, CO

Yuhang Cheng^1*, Xueyan Sun^1*, Meijuan Huang, MD^1*, Lei Zhao, MD, PhD^1*, Jue Wang^1*, Hanyu Wang^1*, Wanying Liu^1*, Shanwei Ye^2*, Liang Huang³, Gaoxiang Wang^1* and Yang Cao^4*

¹Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
²Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, China, Wuhan, China
³Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences, Tianjin, China
⁴Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, San Diego, CA

Sarvarinder Kaur Gill¹, Geeny Lee, PharmD, BCOP^2*, Joelle Rubin, APN^3*, Shuqi Wang^4*, Jamie Koprivnikar, MD^3*, Katherine Linder, MD^3* and James McCloskey, MD³

¹John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ
²Department of Pharmacy, Hackensack University Medical Center, Hackensack, NJ
³Department of Leukemia, John Theurer Cancer Center at Hackensack University Medical Center, Hackensack, NJ
⁴MD Anderson Cancer Center, Houston, TX

Xu Tan^1*, Guo Chen^1*, Yingying Ma^1*, Maihong Wang^1*, Qin Wen, MD^1*, Hong Liu^1*, Xi Zhang, PhD^2,3 and Cheng Zhang, MD, PhD^1*

¹Army Military Medical University, Chongqing, China
²Affiliated xinqiao Hospital of Army medical University,chongqing ,China, chongqing city, China
³Jinfeng Laboratory, Chongqing, China

Asad Bashey, MD, PhD¹, Xu Zhang, PhD^2*, H. Kent Holland, MD^1*, Lawrence E Morris, MD³, Lizamarie Bachier-Rodriguez^1*, Scott R. Solomon, MD³ and Melhem M. Solh, MD³

¹BMT Program at Northside Hospital, Atlanta, GA
²Center for Clinical and Transitional Sciences,, University of Texas, Houston, TX
³Blood and Marrow Transplant Group of Georgia, Atlanta, GA