66th ASH Annual Meeting: 401. Blood Transfusion: Poster I

Symposia: Blood Transfusion Oral and Poster Abstracts
Poster

Research, Acute Myeloid Malignancies, AML, MDS, Fundamental Science, Clinical Practice (Health Services and Quality), Bispecific Antibody Therapy, Drug development, Translational Research, Genomics, Clinical Research, Health outcomes research, Hematopoiesis, Chronic Myeloid Malignancies, Supportive Care, Diseases, Immune mechanism, Treatment Considerations, Biological therapies, Immunology, Immunotherapy, Metabolism, Infusion, Biological Processes, Myeloid Malignancies, Technology and Procedures, Gene editing, Molecular biology, Miscellaneous Cellular Therapies, Transfusion

Halls G-H (San Diego Convention Center)

1265

Cardiovascular Outcome of Heart Failure Patients with Iron Deficiency Anemia Who Received Iron Infusion Vs Red Blood Cell Transfusion: Analysis from a Nationwide Trinetx Database

Hilary A Elom, MD¹^*, Monika Kulasekaran, MD², Lanre Adeniran, MD³^* and Onyedika J Ilonze, MD⁴^*

¹University of Missouri School of Medicine, Columbia, MO
²University of Missouri School of Medicine, Baltimore, MD
³West Virginia University, Morgan town
⁴Indiana University School of Medicine, Indianapolis, IN

1266

Knockout of the Beta-2 Microglobulin Gene in Adipose Tissue-Derived Cells Using CRISPR/CAS9 System for the Generation of Universal HLA Class I Platelets

Lucas Ferioli Catelli, MSc¹^*, Marcus Alexandre Finzi Corat, PhD²^*, Nádia Ghinelli Amôr, PhD¹^*, Irene Santos, MSc¹^*, Fernanda Soares Niemann, MSc¹^*, Adriana da Silva Santos Duarte, PhD¹^* and Sara Teresinha Olalla Saad, MD PhD¹

¹Hematology and Transfusion Medicine Center - Hemocentro, University of Campinas (Unicamp), Campinas, Brazil
²Multidisciplinary Center for Biological Research, University of Campinas (Unicamp), Campinas, Brazil

1267

Higher Rate of Red Blood Cell (RBC) Alloimmunization in RBC-Transfused Myelodysplastic Syndrome Compared to Acute Myeloid Leukemia

Thomas Wiseman^1,2^*, Michaela Spooner, BSc(LabMed)¹^*, Shreyas Khanna^1,2^*, Kevin Hung, MBBS, FRACP, FRCPA¹, Carla Toop, PhD¹^*, Deepak Singhal, MBBS, MD, FRACP, FRCPA¹^*, David T Yeung, MBBS, PhD, BSc, FRACP, FRCPA^1,2,3, Hamish S Scott, PhD^4,5, Christopher N. Hahn, PhD⁴^*, Daniel Thomas, MBBS, PhD^3,4,6^*, Chung How Kok, BSc, PhD^4,5^* and Devendra Hiwase, MD, MBBS, PhD, FRACP, FRCPA^1,2,3,4

¹Royal Adelaide Hospital, Adelaide, SA, Australia
²University of Adelaide, Adelaide, SA, Australia
³South Australian Health and Medical Research Institute, Adelaide, SA, Australia
⁴University of South Australia, Adelaide, SA, Australia
⁵SA Pathology, Adelaide, SA, Australia
⁶Adelaide Medical School, The University of Adelaide, Adelaide, SA, Australia

1268

Standardized Prophylactic Platelet Transfusion Dose for Infants Decreases Platelet Exposure without Increasing Bleeding or Transfusion Frequency

Kristen Coletti, MD¹^*, Matthew Devine¹^*, Sekinah Ajiboye¹^*, Jennifer Taft¹^*, Jeffrey Schinella¹^*, Lori Spotts¹^*, Meagan Sheakoski¹^*, Shannon McGowan¹^*, Kathleen Gibbs¹^*, Carmelita Moultrie-Savage¹^*, Jaleah Hawkins¹^*, David F. Friedman, MD²^*, Michele P. Lambert, MD³ and Christopher S. Thom, MD, PhD⁴

¹Children’s Hospital of Philadelphia, Philadelphia, PA
²Division of Hematology, Children's Hospital of Philadelphia, Philadelphia, PA
³Children's Hospital of Philadelphia, Philadelphia, PA
⁴Division of Neonatology, Children's Hospital of Philadelphia, Philadelphia, PA

1269

Reduction of Lactate Production By Phospholipase C Inhibition in Cold Stored Platelets

Thomas T Oh, PhD¹^*, Jennifer R Talackine²^*, Ji H Lee²^*, Gema D Barrera²^*, Michael A Meledeo, PhD¹^* and Lusha Xiang, MD²^*

¹US Army Institute of Surgical Research, San Antonio, TX
²US Army Institute of Surgical Research, Fort Sam Houston, TX

1270

Tolerance of Anemia: Autologous Stem Cell Transplantation Among Bloodless Medicine Patients Can be Safely Conducted at Lower Hemoglobin Thresholds

Evani Patel, MD¹, Parisa Wootton²^*, Clare Connolly²^*, Patricia A. Locantore-Ford, MD³, Fumei Cerecino⁴^*, Rebecca Pesce-Noga, MS, CSSBB⁴^* and David H. Henry, MD³

¹Division of Hematology/Oncology, Department of Medicine, Penn Medicine, Philadelphia, PA
²School of Medicine, Royal College of Surgeons Ireland, Dublin, Ireland
³Division of Hematology/Oncology, Department of Medicine, Pennsylvania Hospital, Philadelphia, PA
⁴Department of Hematology/Oncology, Pennsylvania Hospital, Philadelphia, PA

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^*signifies non-member of ASH

401.P1.25 401. Blood Transfusion: Poster I