-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

653A.O2.6 653. Multiple Myeloma: Clinical and Epidemiological: Cellular and Molecular Profiling of Multiple Myeloma: Implications for Clinical Practice

Symposia: Multiple Myeloma: Clinical and Epidemiological Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Clinical trials, Translational Research, Epidemiology, Clinical Practice (Health Services and Quality), Assays, Clinical Research, Plasma Cell Disorders, Diseases, Real-world evidence, Lymphoid Malignancies, Computational biology, Emerging technologies, Technology and Procedures, Imaging, Measurable Residual Disease , Molecular testing, Omics technologies
Sunday, December 8, 2024: 9:30 AM-11:00 AM
Pacific Ballroom Salons 21-22 (Marriott Marquis San Diego Marina)
Moderators:
Tobias S. Slørdahl, MD, PhD, St. Olavs Hospital - Trondheim University Hospital and Taxiarchis Kourelis, MD,
Disclosures:
Slørdahl: Pfizer: Consultancy, Honoraria; Abbvie: Honoraria; Takeda: Honoraria; Amgen: Honoraria; Johnsen&Johnsen/Janssen: Consultancy, Honoraria; Bristol Myers Squibb: Consultancy; Menarini Group: Consultancy; GSK: Consultancy; Sanofi: Consultancy.

This session will broadly cover molecular, cellular, and imaging approaches to profile newly diagnosed and relapsed/refractory myeloma.
9:30 AM

Luca Bertamini, MD1*, Cathelijne Fokkema, MD1*, Paula Rodríguez-Otero, MD, PhD2*, Mark van Duin, PhD1*, Niels W.C.J. Van De Donk, MD3, Mattia D'Agostino, MD4*, Evangelos Terpos, MD, PhD5, Diego Vieyra, PhD6*, Ricardo M. Attar, PhD6*, Anna Sitthi-Amorn7*, Robin Carson, MD7, Michel Delforge8*, Christoph Driessen9, Roman Hajek, MD, PhD10, Mario Boccadoro, MD11, Hermann Einsele, MD12, Annette Vangsted13*, Vincent H.J. Van Der Velden, PhD14*, Fredrik Schjesvold, MD, PhD15, Artur Jurczyszyn16*, Meral Beksac, MD17,18, Andrew Spencer, MBBS19*, Annemiek Broijl, PhD20, Tom Cupedo, PhD1*, Philippe Moreau, MD, PhD21* and Pieter Sonneveld, MD1

1Department of Hematology, Erasmus MC Cancer Institute, Rotterdam, Netherlands
2Clinica Universidad de Navarra, Madrid, Spain
3Cancer Center Amsterdam, VU University Medical Center, Amsterdam, Netherlands
4Division of Hematology, AOU Città della Salute e della Scienza di Torino, University of Torino and Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy
5Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Drosia, Attiki, Greece
6Janssen Research & Development, Spring House, PA
7Janssen Research & Development, LLC, Spring House, PA
8Universitair Ziekenhuis (UZ) Leuven, Leuven, Belgium
9Cantonal Hospital St. Gallen, St. Gallen, Switzerland
10University Hospital Ostrava and University of Ostrava, Ostrava, Czech Republic
11European Myeloma Network, EMN, Italy
12Division of Hematology, University Hospital of Wurzburg, Wurzburg, Germany, Würzburg, DEU
13Rigshospitalet, Copenhagen, Denmark
14Department of Immunology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands
15Oslo Myeloma Center, Department of Hematology, Oslo University Hospital, Oslo, Norway
16Jagiellonian University Medical College, Kraków, Poland
17Department of Hematology, Ankara University Faculty of Medicine, Department of Hematology, Ankara, Turkey
18Ankara Liv Hospital, Istinye University, Ankara, Turkey
19Alfred Health-Monash University, Melbourne, VIC, Australia
20Erasmus MC Cancer Institute, Rotterdam, Netherlands
21University Hospital Hôtel-Dieu, Nantes, France

9:45 AM

Nayda Bidikian, MD1,2,3*, Francesco Corrado, MD1,2,3*, Romanos Sklavenitis-Pistofidis, MD1,2,3, Yoshinobu Konishi, MD, PhD1,3,4, Rosa Toenges, MD1,2,3*, Jean-Baptiste Alberge, PhD1,2,3, Michelle P. Aranha, PhD1,2,3*, Ting Wu, MS1*, Michael Timonian, MD2,5*, Shonali Midha, MD2*, Elizabeth K. O'Donnell, MD2, Yuxin Liu, MD2, Sophie Magidson, BS2*, Ashlee Strutevant2*, Kenneth C. Anderson, MD2, Nikhil C. Munshi, MD2, Omar Nadeem, MD2, Gad Getz, PhD1,3,6* and Irene Ghobrial, MD1,2,3

1Broad Institute of MIT and Harvard, Cambridge, MA
2Dana-Farber Cancer Institute, Boston, MA
3Harvard Medical School, Boston, MA
4Dana-Farber Cancer Institute, Brookline, MA
5St. Mary Medical Center, Long Beach, CA
6Krantz Family Center for Cancer Research and Dept. of Pathology, Massachusetts General Hospital, Boston, MA

10:00 AM

Noemi Puig, PhD1,2, Cristina Agullo2*, Bruno Paiva, PhD3,4,5,6*, María T Cedena7*, Laura Rosiñol Dachs8,9,10*, Teresa Contreras11*, Joaquín Martínez-Lopez12,13*, Albert Oriol14,15*, María-Jesús Blanchard, MD, PhD16,17*, Rafael Rios Tamayo, MD, PhD18*, Ana Maria Sureda Balari, MD, PhD19,20,21,22,23,24,25,26,27, Miguel Teodoro Hernández Garcia, MD, PhD28*, Javier de la Rubia29,30*, Valentin Cabanas Perianes, MD, PhD31*, Felipe De Arriba, MD, PhD32*, Luis Palomera, MD, PhD33*, Maria Belen Inigo Rodriguez34*, Veronica Gonzalez-Calle, MD, PhD2,4,35,36*, Enrique M Ocio, MD, PhD37*, Sergio Castro2*, Joan Bargay38*, Joan Bladé, MD, PhD39,40*, Jesús F. San-Miguel, MD, PhD41,42, Juan-Jose Lahuerta Palacios, MD, PhD43,44* and Maria- Victoria Mateos45,46,47,48

1Hospital Universitario de Salamanca (HUSAL), IBSAL, IBMCC (USAL-CSIC), CIBERONC, Salamanca, Spain
2Hospital Universitario de Salamanca, Instituto de Investigacion Biomedica de Salamanca (IBSAL), University of Salamanca, Salamanca, Spain
3Cancer Center Clinica Universidad de Navarra (CCUN)., Pamplona, Spain
4Centro de Investigación Biomédica en Red en Cáncer (CIBERONC), Madrid, Spain
5Department of Hematology, Centre for Applied Medical Research, Cancer Center Clinica Universidad de Navarra, University of Navarra, IdiSNA, CIBERONC, Pamplona, Spain
6Clinica Universidad de Navarra (CCUN), Center for Applied Medical Research (CIMA), IDISNA, CIBER-ONC, Pamplona, Spain
7University Hospital 12 de octubre, Madrid, Spain
8Hospital Clinic de Barcelona, IDIBAPS, Barcelona, Spain
9Hematology Department, Hospital Clinic de Barcelona and Insitut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
10Hospital Clinic of Barcelona, Barcelona, Spain
11Biochemistry Department, University Hospital of Salamanca, Salamanca, ESP
12Hospital Universitario 12 de octubre, Universidad Complutense, CNIO, Madrid, Spain
13University of Complutense, Hospital 12 de Octubre, Madrid, Spain
14Catalan Institute of Oncology and Josep Carreras Institute, Hospital Germans Trias i Pujol, Badalona, Spain
15Institut Josep Carreras and Institut Català d'Oncologia, Hospital Germans Trias i Pujol, Barcelona, Spain
16Hematology, Hospital Universitario Ramón y Cajal, Madrid, Spain
17Hematology, Hospital Universitario Ramon y Cajal, Madrid, Spain
18Hospital Universitario Puerta de Hierro, Majadahonda, Madrid, ESP
19Grupo Español de Trasplante Hematopoyético y Terapia Celular (GETH-TC), Spain, Spain
20Hematology, Institut Català d'Oncologia-Hospitalet, IDIBELL, Universitat de Barcelona, Barcelona, Spain
21Institut Catala d’Oncologia, Barcelona, Spain
22Biomedical Research Institute, Universitat de Barcelona, Barcelona, Spain
23Blood Cell Barcelona Hematology Institute, Barcelona, Spain
24Grupo Español de Trasplante Hematopoyético y Terapia Celular (GETH-TC), Madrid, Spain
25EBMT Lymphoma Working Party, Paris, France
26for the Lymphoma Working Party of the EBMT, Barcelona, Spain
27Institut Català d'Oncologia-Hospital Duran i Reynals, Hospitalet del Llobregat, Spain
28Hospital Universitario de Canarias, La Laguna, ESP
29Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain
30Hospital Universitario y Politécnico La Fe, Valencia, Spain
31Hematology, IMIB-Virgen de la Arrixaca University Hospital, University of Murcia, El Palmar, Murcia, Spain
32Hospital Morales Meseguer, IMIB-Arrixaca, Universidad de Murcia, Murcia, Spain
33Hospital Clinico Universitario Lozano Blesa, Instituto Investigacion Sanitaria Aragon, Zaragoza, Spain
34HOSPITAL CLINICO SAN CARLOS, MADRID, Spain
35Haematology Department, University Hospital of Salamanca, Research Biomedical Institute of Salamanca (IBSAL), CIBERONC and Center for Cancer Research-IBMCC (USAL-CSIC), Salamanca, Spain
36University Hospital of Salamanca/IBSAL/Cancer Research Center-IBMCC (USAL-CSIC), CIBERONC, Salamanca, Salamanca, ESP
37Hospital Universitario Marqués de Valdecilla (IDIVAL), Universidad de Cantabria, Santander, Spain
38Hematology Department, Hospital Universitario Son Llàtzer. IdIsBa., Palma de Mallorca, Spain
39Amyloidosis and Multiple Myeloma Unit, Department of Hematology, IDIBAPS, Hospital Clinic, Spain, Barcelona, Spain
40Hospital Clinic, IDIBAPS, Barcelona, Spain
41Hematology and Cell Therapy Department. Clinica Universidad de Navarra, Instituto de Investigaciones Sanitarias de Navarra (IdiSNA), Cancer Center Clinica Universidad de Navarra (CCUN), Pamplona, Spain
42Clínica Universidad de Navarra, CIMA, IDISNA, CIBER-ONC (CB16/12/00369), Pamplona, Spain
43Hematology, Hospital Universitario 12 de Octubre, Imas12, CIBERONC, Madrid, Spain
44Hospital Universitario 12 de Octubre, CIBER-ONC CB16/12/00369, CNIO, Madrid, Spain
45Hospital Universitario de Salamanca (HUSAL), IBSAL, IBMCC (USAL-CSIC), CIBERONC, Salamanca, Spain, Salamanca, Spain
46Hospital Universitario de Salamanca, Salamanca, Spain
47Institute of Cancer Molecular and Cellular Biology, University Hospital of Salamanca, Salamanca, Spain
48University of Salamanca, Department of Medicine, Salamanca, Spain

10:15 AM

Ioannis Ntanasis-Stathopoulos, MD, PhD, MSc1*, Ioannis V Kostopoulos, PhD2*, Panagiotis Malandrakis, MD1*, Pantelis Rousakis, Msc.3*, Chrysanthi Panteli3*, Evangelos Eleutherakis-Papaiakovou, MD1*, Vasiliki Spiliopoulou, MD1*, Georgia Dimitrakopoulou3*, Despina Fotiou, MD1*, Magdalini Migkou, MD1*, Foteini Theodorakakou, MD1*, Nikolaos Kanellias1*, Maria Gavriatopoulou1*, Efstathios Kastritis, MD, PhD1*, Meletios A. Dimopoulos, MD1, Ourania Tsitsilonis, MD, PhD2* and Evangelos Terpos, MD, PhD4

1Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Athens, Greece
2Department of Biology, School of Science, National and Kapodistrian University of Athens (NKUA), Athens, Greece
3Department of Biology, National and Kapodistrian University of Athens, School of Science, Athens, Greece
4Department of Clinical Therapeutics, National and Kapodistrian University of Athens, School of Medicine, Drosia, Attiki, Greece

10:30 AM

Kentaro Narita, M.D.1*, Youichi Machida2*, Daisuke Ikeda1,3*, Rikako Tabata, M.D.1*, Atsushi Uehara, MD1*, Mitsuaki Oura, M.D.1*, Fuminari Fujii, M.D.1*, Hajime Sakuma, M.D.1*, Masami Takeuchi, M.D.1* and Kosei Matsue, M.D., Ph.D.1

1Division of Hematology/Oncology, Kameda Medical Center, Kamogawa, Chiba, Japan
2Department of Radiology, Kameda Medical Center, Chiba, JPN
3Department of Hematology and Oncology, Okayama University Hospital, Okayama, Japan

10:45 AM

Rosa Toenges, MD1,2,3*, Jean-Baptiste Alberge, PhD1,2,3, Francesco Corrado, MD4*, Nayda Bidikian, MD3*, David M. Cordas Dos Santos, MD3*, Ankit K. Dutta, PhD3*, Elizabeth D. Lightbody, PhD1,2,3, Romanos Sklavenitis Pistofidis, MD, PhD3*, Adam S. Sperling, MD, PhD3*, Kenneth C. Anderson, MD3, Shonali Midha, MD5*, Yuxin Liu, MD3, Jacob P. Laubach3*, Eric L. Smith, MD, PhD3, Nikhil C. Munshi, MD6, Omar Nadeem, MD3, Irene Ghobrial, MD1,2,3 and Gad Getz, PhD1,2,7*

1Harvard Medical School, Boston, MA
2Broad Institute of MIT and Harvard, Cambridge, MA
3Dana-Farber Cancer Institute, Boston, MA
4Department of Medical Oncology, Jerome Lipper Center for Multiple Myeloma Research, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA
5Division of Hematologic Neoplasia, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
6Dana-Farber Cancer Institute, The Jerome Lipper Multiple Myeloma Center, Boston, MA
7Krantz Family Center for Cancer Research and Dept. of Pathology, Massachusetts General Hospital, Boston, MA

*signifies non-member of ASH