-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

651A.O3.6 651. Multiple Myeloma and Plasma Cell Dyscrasias: Basic and Translational: Resistance and Response to Anti-Myeloma Therapies

Symposia: Multiple Myeloma and Plasma Cell Dyscrasias: Basic and Translational Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Combination therapy, Antibody Therapy, Fundamental Science, Apoptosis, Translational Research, Bispecific Antibody Therapy, Plasma Cell Disorders, Genomics, Diseases, Therapy sequence, Immune mechanism, Treatment Considerations, Biological therapies, Immunology, Lymphoid Malignancies, Computational biology, Biological Processes, Technology and Procedures, Molecular biology, Profiling, Imaging, Omics technologies
Sunday, December 8, 2024: 12:00 PM-1:30 PM
San Diego Ballroom AB (Marriott Marquis San Diego Marina)
Moderators:
Francesca Cottini, MD, The Ohio State University Comprehensive Cancer Center and Holly Lee, MD,
Disclosures:
Cottini: Sanofi: Honoraria, Membership on an entity's Board of Directors or advisory committees.
12:00 PM

Adolfo Aleman, Jr.1*, Rongbao Zhao, PhD2,3*, Leah Grossman4*, Rahul Sanawar, PhD2*, Srinivas Aluri, PhD2, Mani Mohindru, PhD5*, Rudra Prasad Dutta6*, Sidorela Reci, BS7*, Junia Vieira, MD, PhD1*, David Melnekoff, PhD1*, Alessandro Lagana, PhD8, Shriya Desai, BS9*, Sundar Jagannath8,10, Amit Verma, MD2 and Samir Parekh, MD1

1Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY
2Blood Cancer Institute, Department of Oncology, Albert Einstein College of Medicine, Bronx, NY
3Montefiore Einstein Cancer Center, Blood Cancer Institute, Department of Oncology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY
4Icahn School of Medicine at Mt. Sinai, New York, NY
5Roshon Therapeutics, Scarsdale, NY
6Hematology and Molecular Oncology, Icahn School of Medicine at Mt. Sinai, New York, NY
7Department of Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY
8Department of Medicine, Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York
9Hematology and Medical Oncology, Icahn School of Medicine at Mt. Sinai, New York, NY
10Mount Sinai Medical Center, New York, NY

12:15 PM

Yoshinobu Konishi, MD, PhD1,2,3, David M. Cordas Dos Santos, MD1,3,4*, Jacopo U. Verga3,4,5,6*, Patrick Costello, MS4*, Sujal I. Shah, MD7*, Qanber Raze, PhD8*, Liang S. Lim, PhD8*, Arnaldo G. Barican8*, David Howell8*, David King, PhD8*, Katherine Towle4*, Ruben D. Carrasco, MD, PhD4,7*, Scott J. Rodig, MD, PhD7, Jon C. Aster, MD, PhD7, Adam S. Sperling, MD, PhD1,3,4,7, Eric L. Smith, MD, PhD1,3,4, Jacob Laubach1,4,7, Nikhil C. Munshi, MD1,4,7, Kenneth C. Anderson, MD1,4, Omar Nadeem, MD1,3,4 and Irene Ghobrial, MD1,3,4

1Harvard Medical School, Boston, MA
2Dana-Farber Cancer Institute, Brookline, MA
3Broad Institute of MIT and Harvard, Cambridge, MA
4Dana-Farber Cancer Institute, Boston, MA
5Centre for Research Training in Genomics Data Science, University of Galway, Galway, Ireland
6Apoptosis Research Centre, School of Biological and Chemical Sciences, University of Galway, Galway, Ireland
7Brigham & Women's Hospital, Boston, MA
8Standard BioTools Canada Inc., Markham, ON, Canada

12:30 PM

David Jung, BSc1*, Holly Lee, MD1, Sejal Chikhale1*, Mansour Poorebrahim, PhD1*, Sungwoo Ahn, PhD1*, Sacha Benaoudia, PhD1*, Noemie Leblay, PhD1*, Francesco Maura, MD2, Nizar J. Bahlis, MD1 and Paola Neri, MD, PhD1

1Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada
2University of Miami, Coral Gables, FL

12:45 PM

Benjamin Diamond, MD1, Linda B. Baughn, PhD2, Mansour Poorebrahim, PhD3*, Alexandra Maria Poos, PhD4*, Holly Lee, MD3, Marcella Kaddoura, MD5, J Erin Wiedmeier-Nutor, MD, MPH6, Michael Durante, MD, PhD7*, Gregory Otteson8*, Dragan Jevremovic, M.D., Ph.D9*, Hongwei Tang, PhD2*, Stefan Frohling, MD10*, Marios Papadimitriou, MD1*, Bachisio Ziccheddu1*, Tomas Jelinek11, Ola Landgren1, Paola Neri, MD, PhD3, P. Leif Bergsagel, MD12, Esteban Braggio, PhD13, Shaji Kumar, MD14, Marc S. Raab4*, Rafael Fonseca, MD15, Nizar J. Bahlis, MD3, Niels Weinhold, PhD4* and Francesco Maura, MD1

1Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
2Division of Laboratory Genetics, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
3Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada
4Heidelberg Myeloma Center, Department of Medicine V, University Hospital Heidelberg, Heidelberg, Germany
5Myeloma Institute, Sylvester Comprehensive Cancer Center, University of Miami, Dearborn, MI
6Division of Hematology, Mayo Clinic, Phoenix, AZ
7University of Miami Miller School of Medicine, Miami, FL
8Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
9Mayo Clinic, Rochester, MN
10National Center For Tumor Diseases, Heidelberg, DEU
11Department of Hematooncology, University Hospital Ostrava, Ostrava, Ostrava-Mesto, Czech Republic
12Division of Hematology/Oncology, Mayo Clinic, Phoenix, AZ
13Division of Hematology and Oncology, Mayo Clinic, Scottsdale, AZ
14Division of Hematology, Mayo Clinic, Rochester, MN
15Division of Hematology, Mayo Clinic, Paradise Valley, AZ

1:00 PM

Umair Munawar1*, Seungbin Han2*, Silvia Nerreter2*, Cornelia Vogt2*, Shilpa Kurian2*, Patrick Eiring, PhD3*, Julia Weingart3*, Xiang Zhou, MD, BMBS2, Markus Sauer, PhD3*, Hermann Einsele, MD4, Leo Rasche, MD5*, Johannes Waldschmidt, MD2 and K. Martin Kortüm, MD2*

1University Hospital of Wuerzburg, Wuerzburg, Germany
2Department of Internal Medicine II, University Hospital Wuerzburg, Wuerzburg, Germany
3Department of Biotechnology and Biophysics, University of Würzburg, Würzburg, Germany
4Department of Internal Medicine II, University Hospital Würzburg, Würzburg, Germany
5Department of Internal Medicine II, University Hospital Wurzburg, Wurzburg, Germany

1:15 PM

Deeksha Vishwamitra1, Sheri Skerget, PhD1*, Diana Cortes-Selva, PhD2*, Kalpana Bakshi1*, Lien Vandenberk, PhD3*, Weili Sun, PhD4, Jaszianne Tolbert, MD1, Colleen Kane, PhD1, Hein Ludlage, MSc5*, Bas D Koster, MD, PhD6, Julie S Larsen, PharmD4*, Tobias Kampfenkel, MD, MHBA7*, Ching Li1*, Farheen Zishan8*, Thomas Prior, PhD1*, Luciano J. Costa, MD, PhD9, Jesus G Berdeja, MD10, Cyrille Touzeau, MD, PhD11*, Aurore Perrot, MD, PhD12, Emma Searle, MD, PhD13*, Jeffrey V Matous, MD14, Ajai Chari, MD15, Donna Reece, MD16, Manisha Bhutani, MD17, Bhagirathbhai R. Dholaria, MBBS18, Anita D'Souza, MD, MS19*, Thomas G. Martin, MD15, John T. McKay20*, Alfred L Garfall21*, Amrita Y Krishnan, MD, FACP22, Niels W.C.J. van de Donk, MD, PhD23*, Nizar J. Bahlis, MD24 and Ricardo M. Attar, PhD1*

1Janssen Research & Development, Spring House, PA
2Johnson & Johnson Innovative Medicine, Spring House, PA
3Janssen Research & Development, Antwerp, Belgium
4Janssen Research & Development, Los Angeles, CA
5Janssen-Cilag Benelux, Leiden, Netherlands
6Janssen Biologics Europe, Leiden, Netherlands
7Janssen Research & Development, Neuss, Germany
8Janssen Research & Development, High Wycombe, United Kingdom
9University of Alabama at Birmingham, Birmingham, AL
10Tennessee Oncology, Sarah Cannon Research Institute, Nashville, TN
11Centre Hospitalier Universitaire de Nantes, Nantes, France
12Centre Hospitalier Universitaire de Toulouse, Oncopole, Toulouse, France
13The University of Manchester, Manchester, United Kingdom
14Sarah Cannon Research Institute, Colorado Blood Cancer Institute, Denver, CO
15University of California, San Francisco, San Francisco, CA
16Princess Margaret Cancer Centre, Toronto, ON, Canada
17Atrium Health Levine Cancer Institute/ Wake Forest School of Medicine, Charlotte, NC
18Vanderbilt University Medical Center, Nashville, TN
19Medical College of Wisconsin, Milwaukee, WI
20Wake Forest University School of Medicine, Winston-Salem, NC
21Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
22City of Hope Comprehensive Cancer Center, Duarte, CA
23Amsterdam University Medical Center, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
24Arnie Charbonneau Cancer Institute, University of Calgary, Calgary, AB, Canada

*signifies non-member of ASH