Quentin Kimmerlin^1*, Marc Usart^1*, Tiago Fonseca^1*, Hui Hao-Shen^2* and Radek C. Skoda, MD¹

¹Experimental Hematology, Department of Biomedicine, University Hospital Basel and University of Basel, Basel, Switzerland
²Department of Biomedicine, Experimental Hematology, University Hospital Basel and University of Basel, Basel, Switzerland

Camelia Benlabiod, PhD^1*, Gurvan Hermange, PhD^2*, Laetitia Borderon^1*, Quentin Blampey^2*, Maxime Evrard^1*, Antonio Rodriguez Romera^3*, Stéphanie G. Moreno^4*, Nathalie Gault^4*, Philippe Rameau^5*, Cyril Catelain^5*, Elodie Rosa^1*, Bethan Psaila, MD, PhD^6,7, Claus Nerlov, PhD^8*, Sten Eirik Waelgaard Jacobsen, MD, PhD^9,10*, William Vainchenker, MD, PhD^1*, Hana Raslova, PhD^1*, Paul-Henry Cournède, PhD^2*, Isabelle Plo, PhD^1* and Caroline Marty, PhD^1*

¹INSERM UMR1287, Gustave Roussy, Paris-Saclay University, Villejuif, France
²Laboratory of Applied Mathematics and Computer Sciences (MICS), Université Paris-Saclay, CentraleSupélec, Gif-sur-Yvette, France
³Medical Research Council Weatherall Institute of Molecular Medicine (MRC WIMM) and NIHR Biomedical Research Centre Hematology Theme, University of Oxford, Oxford, ENG, United Kingdom
⁴INSERM UMR1274, CEA - DRF/ IBFJ/ iRCM/ LSHL, Fontenay-aux-Roses, France
⁵UMS AMMICa-Plateforme Imagerie et Cytométries, Gustave Roussy, Villejuif, FRA
⁶Medical Research Council (MRC) Weatherall Institute of Molecular Medicine (WIMM), University of Oxford, Oxford, ENG, United Kingdom
⁷Oxford University Hospitals NHS Trust, Oxford, United Kingdom
⁸MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom
⁹Center for Hematology and Regenerative Medicine (HERM) - Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden
¹⁰MRC Molecular Haematology Unit - MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom

Ian Ghezzi^1,2*, Sercan Öz^1*, Istiffa Nurfauziah^1*, Sena Alptekin, MD^1,2*, Esther Rodriguez-Correa, PhD^1,2*, Lena Bognar^1,2*, Foteini Fotopoulou, PhD^1,2* and Michael D. Milsom, PhD^3,4

¹German Cancer Research Center (DKFZ), Heidelberg, Germany
²HI-STEM Ggmbh, Heidelberg, Germany
³HI-STEM Ggmbh, Heidelberg, DEU
⁴Division of Experimental Hematology, DKFZ, Heidelberg, Germary, Heidelberg, DEU

Dennis M Bonal, MSc, BSc^1,2,3, Anna Dorota Chorzalska, PhD^4,5,6*, Alissa Oakes, PhD^6,7*, Makayla R Pardo⁸, Seo-Ho Lee^4,9*, Michael Y Clarke^6*, Max Petersen^6*, Hyunju Oh, BS^5*, Valeria Brown^6*, Diana Olguta Treaba, MD^10*, John L. Reagan, MD^1,11,12,13, Adam J. Olszewski, MD^6,14,15, Mark Dooner^16*, John Morgan, PhD^4*, Joslyn Mills, PhD^17*, Paul Bertone, PhD^3,7* and Patrycja M Dubielecka, PhD^3,7,8,18

¹Legorreta Cancer Center, Brown University, Providence, RI
²Pathobiology Graduate Program, Brown University, Douglas, MA
³Warren Alpert Medical School of Brown University, Providence, RI
⁴Dubielecka Lab, Rhode Island Hospital, Providence, RI
⁵Warren Alpert Medical School, Brown University, Providence, RI
⁶Brown University, Providence, RI
⁷Legorreta Cancer Center of Brown University, Providence, RI
⁸Pathobiology Graduate Program, Brown University, Providence, RI
⁹Legorreta Cancer Center, Brown University, Amherst, MA
¹⁰Rhode Island Hospital, Department of Pathology and Laboratory Medicine, Providence, RI
¹¹Brown University Health Cancer Institute, Warren Alpert Medical School of Brown University, Providence, RI
¹²Brown University Health Cancer Insitute, Warren Alpert Medical School of Brown University, Providence, RI
¹³Brown University Health Cancer Institute, Brown University Health, Providence, RI
¹⁴Brown Univeristy, Providence, RI
¹⁵Lifespan Cancer Institute, Rhode Island Hospital, Providence, RI
¹⁶Lifespan Cancer Institute Providence, Providence
¹⁷Biology Department, Bridgewater State University, Bridgewater, MA
¹⁸Rhode Island Hospital and Warren Alpert Medical School At Brown University, Providence, RI

Tyler M Parsons, PhD¹, Aishwarya Krishnan, MS¹, Andrew L Young, MD, PhD², Maggie Cox^3*, Stephen Oh, MD, PhD⁴ and Grant A Challen, PhD⁵

¹Oncology, Washington University School of Medicine in St. Louis, St. Louis, MO
²Division of Hematology, Washington University School of Medicine in St. Louis, St. Louis, MO
³Division of Hematology, Department of Medicine, Washington University School of Medicine, St Louis, MO
⁴Washington University School of Medicine, Saint Louis, MO
⁵Division of Oncology, Washington University School of Medicine, St. Louis, MO

Linda Resar, MD¹, Joseph Kim^2,3, Audrey-Ann Supreme, BS^4,5*, Hyunsung Woo, MS^6*, Bailey West, BS^7*, Mariah C. Antopia, BS^8*, Zanshe Thompson, PhD, MS⁹, Karen Reddy, PhD^10*, Jung-Hyun Kim, PhD^10*, Leslie Cope, PhD^2*, Raajit Rampal, MD, PhD¹¹, Richard Koche, PhD^12,13*, Alison R. Moliterno, MD¹⁴ and Jerry L. Spivak, MD¹⁵

¹Division of Hematology, Departments of Medicine, Oncology & Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD
²Johns Hopkins University School of Medicine, Baltimore, MD
³Cellular and Molecular Medicine Graduate Program, Johns Hopkins University School of Medicine, Baltimore, MD
⁴Doctoral Diversity Program, Johns Hopkins University School of Medicine, Baltimore, MD
⁵Department of Medicine, Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, MD
⁶Whiting School of Engineering, The Johns Hopkins University, Baltimore, MD
⁷Pathobiology Graduate Program, Johns Hopkins University School of Medicine, Baltimore, MD
⁸The Institute for Basic Biomedical Sciences, Johns Hopkins University School of Medicine, Baltimore, MD
⁹Division of Hematology, The Johns Hopkins University School of Medicine, Owings Mills, MD
¹⁰The Johns Hopkins University School of Medicine, Baltimore, MD
¹¹Memorial Sloan Kettering Cancer Center, New York, NY
¹²Center for Epigenetics Research, Memorial Sloan Kettering Cancer Center, New York, NY
¹³Human Oncology and Pathogenesis Program, Leukemia Service, Department of Medicine, Center for Epigenetics, Memorial Sloan Kettering Cancer Center, New York, NY
¹⁴Division of Hematology, Department of Medicine, Johns Hopkins University/Fda, Silver Spring, MD
¹⁵Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD