-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

626.O2.3 626. Aggressive Lymphomas: Clinical and Epidemiological: Challenging Subtypes of Aggressive Lymphomas

Symposia: Aggressive Lymphomas: Clinical and Epidemiological Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Clinical trials, Lymphomas, Non-Hodgkin lymphoma, Epidemiology, Clinical Research, B Cell lymphoma, Chemotherapy, Diseases, Real-world evidence, Aggressive lymphoma, Treatment Considerations, Lymphoid Malignancies, Non-Biological therapies, Adverse Events
Sunday, December 8, 2024: 12:00 PM-1:30 PM
Marriott Grand Ballroom 5-6 (Marriott Marquis San Diego Marina)
Moderators:
Alvaro J Alencar, MD, University of Miami Miller School of Medicine and Kathryn Lurain, MD, MPH, National Cancer Institute
Disclosures:
Lurain: BMS-Celgene: Research Funding; Merck: Research Funding; Johnson and Johnson Pharmaceuticals: Research Funding; CTI BioPharma/SOBI: Research Funding; Lentigen: Research Funding; Eli Lilly: Research Funding; EMD-Serrono: Research Funding; PDS Biopharma: Research Funding.

In this session studies on management of primary and secondary central nervous system lymphoma will be presented.
12:00 PM

Juan Pablo Alderuccio, MD1, Jahanzaib Khwaja2, Sunwoo Han, PhD3*, Paola Ghione, MD, MSEpi4, Imran A. Nizamuddin, MD5, Aditi Saha, MBBS6, Ning Dong, MD7, Yucai Wang, MD, PhD8, Hua-Jay J Cherng9*, Seda S. Tolu, MD10, Nina D. Wagner-Johnston, MD11, Adam J. Olszewski, MD12, Natalie Grover, MD13, Jean L. Koff, MD, MSc14, Amrita Desai, MD, MPH15, Praveen Ramakrishnan Geethakumari, MD, MS16, Tamara K Moyo, MD17*, Jose Sandoval-Sus, MD18, Narendranath Epperla, MD MS19, Danielle S Wallace, MD20, Manali Kamdar, MD, MBBS21*, Alexey Danilov, MD, PhD22, Han W. Tun, MD23, Javier Munoz, MD24*, Mayur S. Narkhede, MD25, Joanna M. Rhodes, MD, MSCE26*, Anca Prica, MD, MSc27*, Andrea Kuhnl28*, Adrian Maraj, FRCPath, MBBChir, MRCP29*, Jessica Okosun, MB BChir PhD30, Jeffery Smith, MBChB BMedSci MRCP FRCPath31*, Wendy Osborne, MD32*, Victoria Calvert33*, Dima el-Sharkawi34*, Ammar Hilali35*, Graham P. Collins36, Kim Linton37*, Nagah Elmusharaf38*, Anna Santarsieri, MBBS39*, Farheen Karim40*, Thomas Ollila, MD12, Sarah Monick, MD41*, Iris Margalit Trutzer, MD, PhD42*, Nilanjan Ghosh43*, Jones Can, MD44*, Amy Ayers, MPH14*, Jacopo Calabrese De Feo, MD45*, John Sharp, MD46, Rachel Treitman, BS47*, Avyakta Kallam, MD48*, Izel Okcu8*, Vismay Deshani49*, Firas Baidoun, MD50*, Chathuri Abeyakoon51*, William Hann52*, Aisling Barrett, FRCPath, MB53*, Brad Kahl, MD54*, Julio C. Chavez, MD55 and Kate Cwynarski, MBBS, PhD, FRCP, FRCPath56*

1Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
2University College London Hospitals NHS Foundation Trust, Sidcup, United Kingdom
3Biostatistics and Bioinformatics Shared Resource, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL
4Memorial Sloan Kettering Cancer Center, New York, NY
5Division of Oncology, Washington University School of Medicine, St. Louis, MO
6Department of Hematology/Oncology, Moffitt Cancer Center, West Orange, NJ
7H Lee Moffitt Cancer Center & Research Institute, Tampa
8Division of Hematology, Mayo Clinic, Rochester, MN
9Columbia University Irving Medical Center, New York, NY
10Division of Hematology & Oncology, Columbia University Irving Medical Center, New York City, NY
11Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Hospital, Baltimore, MD
12Brown University, Providence, RI
13University of North Carolina, Chapel Hill, NC
14Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA
15Knight Cancer Institute, Oregon Health & Science University, Portland, OR
16Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern, Dallas, TX
17Department of Hematologic Oncology and Blood Disorders, Atrium Health Levine Cancer Institute, Charlotte, NC
18Moffitt Cancer Center at Memorial Healthcare System, Pembroke Pines, FL
19Ohio State University, Columbus, OH
20Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, NY
21Division of Hematology, Hematologic Malignancies and Stem Cell Transplant, University of Colorado Cancer Center, Aurora, CO
22City of Hope Comprehensive Cancer Center, La Canada Flintridge, CA
23Division of Hematology and Medical Oncology, Mayo Clinic, Jacksonville, FL
24Mayo Clinic, Phoenix, AZ
25Department of Hematology Oncology, University of Alabama at Birmingham, Birmingham, AL
26Rutgers Cancer Institute of New Jersey, New Brunswick, NJ
27Division of Medical Oncology and Hematology, Princess Margaret Cancer Centre - University Health Network, Toronto, ON, Canada
28King's College Hospital NHS Foundation Trust, London, United Kingdom
29St James Hospital, Dublin, Ireland
30Department of Haemato-Oncology, Barts Hospital, London, ENG, United Kingdom
31The Clatterbridge Cancer Centre NHS Foundation Trust, Liverpool, United Kingdom
32Newcastle Hospitals NHS Trust, Newcastle Upon Tyne, United Kingdom
33Freeman Hospital, Newcastle University, Newcastle, United Kingdom
34The Royal Marsden NHS Foundation Trust, London, United Kingdom
35Royal Marsden NHS Foundation Trust, London, United Kingdom
36Oxford Cancer and Haematology Centre, Oxford, United Kingdom
37The Christie NHS Foundation Trust, Manchester Cancer Research Centre, and Division of Cancer Sciences, University of Manchester, Manchester, United Kingdom
38University Hospital of Wales, Cardiff, United Kingdom
39Cambridge University Hospitals NHS Trust, Cambridge, United Kingdom
40The Royal Wolverhampton NHS Trust, Wolverhampton, GBR
41Mayo Clinic Arizona, Phoenix
42The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore
43Levine Cancer Institute, Atrium Health, Charlotte, NC
44Moffitt Malignant Hematology at Memorial Healthcare System, Pembroke Pines
45Memorial Sloan Kettering Cancer Center, New York City
46James Comprehensive Cancer Center, The Ohio State University, Columbus, OH
47University of Colorado School of Medicine, Denver, CO
48City of Hope National Medical Center, Duarte, CA
49The Christie NHS Foundation Trust, Manchester, United Kingdom
50Division of Hematology-Oncology, Mayo Clinic-Florida, Jacksonville, FL
51Princess Margaret Cancer Centre, Toronto, Canada
52Barts Cancer Institute, London, United Kingdom
53Oxford University Hospital, Oxford, ENG, GBR
54Washington University Medical School, St Louis, MO
55Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
56University College London, London, United Kingdom

12:15 PM

Motoo Nagane1*, Manabu Natsumeda, MD, PhD2,3*, Fumiharu Ohka, MD, PhD4*, Fumiyuki Yamasaki, MD, PhD5*, Hajime Yonezawa, MD, PhD6*, Nobuyoshi Sasaki7*, Shigeru Yamaguchi, MD, PhD8*, Kensuke Tateishi, MD, PhD9*, Yoshitaka Narita, MD, PhD10*, Yasukazu Kawai, MD, PhD11*, Hiroyuki Sugahara, MD, PhD12*, Jyunichiro Kuroda, MD, PhD13*, Takeshi Okuda, MD, PhD14*, Tomoo Matsutani, MD, PhD15*, Manabu Kinoshita, MD, PhD16*, Naoto Tomita, MD, PhD17, Keiichiro Hattori, MD, PhD18*, Jun Muto, MD, PhD19*, Noriaki Kitamura, MD20*, Keita Kinoshita, PhD21* and Kazuhiko Mishima, MD, PhD22*

1Department of Neurosurgery, Kyorin University Faculty of Medicine, Mitaka, Tokyo, Japan
2Advanced Treatment of Neurological Diseases Branch, Brain Research Institute, Niigata University, Niigata, Japan
3Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan
4Department of Neurosurgery, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan
5Department of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan
6Department of Neurosurgery, Kagoshima University Hospital, Kagoshima, Japan
7Department of Neurosurgery, Kyorin University Faculty of Medicine, Tokyo, Japan
8Departments of Neurosurgery, Faculty of Medicine, Hokkaido University, Sapporo, Japan
9Department of Neurosurgery, Graduate School of Medicine, Yokohama City University, Yokohama, Japan
10Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, Tokyo, Japan
11Department of Hematology and Oncology, Fukui Prefectural Hospital, Fukui, Japan
12Department of Hematology, Sumitomo Hospital, Osaka, Japan
13Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
14Department of Neurosurgery, Kindai University Faculty of Medicine, Osaka, Japan
15Department of Neurological Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan
16Department of Neurosurgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan
17Hematology and Oncology, St. Marianna University School of Medicine, Kanagawa, Japan
18Department of Hematology, Institute of Medicine, University of Tsukuba, Tsukuba, Japan
19Department of Neurosurgery, Fujita Health University, Aichi, Japan
20Department of Hematology, University of Occupational and Environmental Health, Kitakyushu, Japan
21Oncology Medical Affairs, Ono Pharmaceutical Co., Ltd., Osaka, Japan
22Department of Neuro-Oncology/Neurosurgery, Saitama Medical University International Medical Center, Saitama, Japan

12:30 PM

Matthew Hamby, BSc1, Brian Egleston, PhD2*, Zachary AK Frosch, MD, MSHP3, Raphael E. Steiner, MD4, Ariela Noy, MD4, Veronica Carvajal, BS5*, Seda S. Tolu, MD6, Gaston Jean-Louis, MD7*, Jennifer E. Amengual, MD8, Romil Patel, MD9, Sairah Ahmed, MD9,10,11, Timothy Voorhees, MD, MSc12, Robert Baiocchi, MD, PhD13, Andres Ramirez-Gamero, MD14*, Jorge J. Castillo, MD14,15, Emily Hamburger, MD16*, Christopher Dittus, DO16, Imran A. Nizamuddin, MD17, Neha Mehta-Shah, MD18,19, Nyein Nyein Thaw Dar, MBBS, MSc20*, Jose Sandoval-Sus, MD21, Alexandra E. Rojek, MD22, Peter A. Riedell, MD22, Vinod Solipuram, MD23*, Paul G. Rubinstein, MD24, Anthony Ariotti25*, Gita Suneja, MD, MS25*, Alexander Vartanov, MD26, Charles Milrod, MD27, Adam J. Olszewski, MD28, Gordon Smilnak, MD29*, Emily Ayers, MD29, Sahaj Desai, MD30*, Joanna M. Rhodes, MD30, Gabriella Magarelli, MSN, ACNP-BC, AOCNP31*, Tatyana Feldman, MD32, Meredith Pellon33*, David M. Aboulafia, MD34*, William Bae, MD35, Carlos Galvez, MD35, Vineel Bhatlapenumarthi, MD36*, Mehdi Hamadani, MD37 and Stefan K. Barta, MD38,39

1University of Pennsylvania, Lancaster, PA
2Fox Chase Cancer Center, Philadelphia, PA
3Department of Hematology/Oncology; Cancer Prevention and Control Research Program, Fox Chase Cancer Center, Philadelphia, PA
4Lymphoma Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
5Lymphoma Program, Abramson Cancer Center, University of Pennsylvania, Philadelphia
6Division of Hematology & Oncology, Columbia University Irving Medical Center, New York City, NY
7Columbia University, New York, NY
8Division of Hematology & Oncology, Columbia University Irving Medical Center, New York
9Department of Lymphoma and Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX
10Department of Lymphoma/Myeloma and Stem Cell Transplantation, The University of Texas MD Anderson Cancer Center, Houston, TX
11MD Anderson Cancer Center, Houston, TX
12Division of Hematology, The Ohio State University, Columbus, OH
13James Comprehensive Cancer Center, The Ohio State University, Columbus, OH
14Dana-Farber Cancer Institute, Bing Center for Waldenström Macroglobulinemia, Boston, MA
15Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA
16Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC
17Division of Oncology, Washington University School of Medicine, St. Louis, MO
18Siteman Cancer Center, Washington University in St. Louis, St Louis, MO
19Siteman Cancer Center, Washington University School of Medicine, Olivette, MO
20Moffitt Cancer Center at Memorial Healthcare System, Pembroke Pines, FL
21Department of Malignant Hematology and Cellular Therapy, Moffitt Cancer Center at Memorial Healthcare System, Pembroke Pines, FL
22Department of Medicine, Section of Hematology/Oncology, University of Chicago, Chicago, IL
23John H. Stroger Jr. Hospital of Cook County, Chicago
24John Stroger Cook County Hospital, Chicago, IL
25Huntsman Cancer Institute, University of Utah, Salt Lake City, UT
26Department of Hematology/Oncology, Fox Chase Cancer Center, Philadelphia, PA
27Department of Hematology/Oncology, Brown University, Providence, RI
28Brown University, Providence, RI
29University of Virginia, Charlottesville, VA
30Rutgers Cancer Institute of New Jersey, New Brunswick, NJ
31John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ
32Hackensack Meridian Health Hackensack University Medical Center, NY, NY
33Virginia Mason Medical Center, Seattle, WA
34Virginia Mason Clinic, Seattle, WA
35Division of Hematology/Oncology, University of Illinois at Chicago, Chicago, IL
36Department of Hematology-Oncology, Medical College of Wisconsin, Milwaukee, WI
37Department of Medicine, Medical College of Wisconsin, Milwaukee, WI
38Division of Hematology-Oncology, Perelman Center for Advanced Medicine, University of Pennsylvania, Philadelphia, PA
39Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA

12:45 PM

Jiayu Yang, MD1, Anna R. Hayden, MD1, Diego Villa, MD1,2, Aixiang Jiang, MS3*, Alina S. Gerrie, MD, MPH1,3, Christopher P. Venner, MD1,3, Pedro Farinha3,4, David W. Scott, MBChB, PhD1,3, Laurie H. H. Sehn, MD1,3 and Kerry J. Savage, MD, MSc1,3

1Division of Medical Oncology, University of British Columbia, Vancouver, BC, Canada
2Centre for Lymphoid Cancer, BC Cancer – Vancouver Cancer Centre, Vancouver, BC, Canada
3Centre for Lymphoid Cancer, BC Cancer, Vancouver, BC, Canada
4Department of Pathology, University of British Columbia, Vancouver, BC, Canada

1:00 PM

Vincent Camus, MD, PhD1,2*, Thierry Jo Molina, MD, PhD3*, Fabienne Desmots-Loyer, PhD4*, Amine Moslemi, MD5*, Philippe Ruminy, PhD2*, Steven Le Gouill, MD, PhD6, Herve Ghesquieres, MD, PhD7*, Lucie Oberic, MD8*, Franck Morschhauser9, Hervé Tilly2, Vincent Ribrag, MD10, Roch Houot, MD, PhD11*, Catherine Thieblemont, MD12, Herve Maisonneuve, MD13*, Fabien Claves, MD14*, Krimo Bouabdallah, MD15*, Corinne Haioun, MD, PhD16, Gandhi Damaj, MD, PhD17*, Luc-Matthieu Fornecker, MD, PhD18*, Robin Noel, MD19*, Pierre Feugier, MD, PhD20*, David Sibon, MD, PhD21*, Guillaume Cartron, MD, PhD22,23*, Christophe Bonnet, MD, PhD24*, Marc André, MD, PhD25*, Françoise Kraeber-Bodéré, MD, PhD26,27*, Caroline Milin, MD, PhD26,27*, Jean-Philippe Jais, MD, PhD28*, Josette Briere, MD29*, Olivier Casasnovas, MD30,31*, Salim Kanoun, MD32,33*, Emmanuel Itti, MD, PhD34*, Paul Blanc-Durand35*, Mad-Hélénie Elsensohn36*, Loic Chartier37*, Fabrice Jardin, MD, PhD2* and Thierry Fest, MD, PhD38,39*

1Centre Henri Becquerel, Department of Hematology, Rouen, France
2INSERM U1245, Cancer and Brain Genomics, Centre Henri Becquerel, University of Rouen, Rouen, France
3Department of Pathology, Assistance Publique-Hôpitaux de Paris, Necker and Robert Debré Hospital, Université Paris Cité, Paris, France
4Laboratoire d'Hématologie, Université de Rennes 1, INSERM, Établissement Français du Sang de Bretagne, Team B_DEVIL, UMR_S1236, Rennes, France; Centre Hospitalier Universitaire, RENNES, France
5Department of Pathology, Amiens University Hospital, Amiens, FRA
6Institut Curie, Saint-Cloud, France
7Department of Hematology, Centre Hospitalier Lyon-Sud, Hospices Civils de Lyon, Université Claude Bernard Lyon 1, Lyon, France
8IUCT - Oncopole, Hematology Department, Toulouse, France
9Centre Hospitalier Universitaire de Lille - Hopital Claude Huriez, Lille, France
10Département d'Innovation Thérapeutique et d'Essais Précoces (DITEP), Gustave Roussy Institute of Cancer, Villejuif, France
11Hematology department, CHU Rennes - Hopital Pontchaillou, Rennes, France
12Hospital Saint-Louis, Paris, France
13Centre Hospitalier Departemental de Vendée, La Roche-sur-Yon, FRA
14Department of Hematology, University Hospital Grenoble - HOPITAL ALBERT MICHALLON, Grenoble, France
15Bordeaux university hospital, Haut-Leveque, Department of hematology, Bordeaux, France
16Lymphoid Malignancies Department, Henri Mondor University Hospital, AP-HP, Créteil, France
17CHU Caen, Caen, Normandy, FRA
18Institut De Cancérologie Strasbourg Europe, Hematology Department, Strasbourg, France
19Institut Paoli-Calmettes, Marseille, FRA
20CHU Brabois - Service d'Hématologie - Université Henri Poincaré, Nancy, France
21Lymphoid Hematology Department, Henri Mondor University Hospital, AP-HP, Paris, France
22Centre Hospitalier Universitaire de Montpellier, Montpellier, France
23Montpellier University Hospital Center, UMR CNRS 5535, Montpellier, France
24Hématologie clinique, CHU de Liège, Université de Liège, Liège, Belgium
25CHU UCL Namur, Yvoir, Belgium
26CRCINA, INSERM, CNRS, Université d'Angers, Université de Nantes, Nantes, France
27Department of Nuclear Medicine, University Hospital of Nantes, Nantes, France
28Hôpital Necker-Enfants Malades, PARIS, France
29University Hospital Henri-Mondor, APHP, INSERM U955, Créteil, FRA
30François Mitterand Hospital, Dijon, FRA
31INSERM 1231, Dijon, France
32Pixilib SAS, ; Centre de Recherche Clinique de Toulouse, Team 9 INSERM Unité Mixte de Recherche 1037, Toulouse, France
33Nucear Medicine Department, IUCT Oncopole, Toulouse, France
34Nuclear medicine department, Henri Mondor University Hospital, AP-HP, Créteil, FRA
35CHU Henri Mondor, Creteil, FRA
36Lymphoma Academic Research Organization (LYSARC), Lyon, France
37Department of Biostatistics, Lymphoma Academic Research Organization (LYSARC), Lyon, France
38Inserm, Université de Rennes 1, Rennes, France
39Laboratoire d'Hématologie, Centre Hospitalier Universitaire de Rennes, INSERM, Établissement Français du Sang de Bretagne, Team B_DEVIL, UMR_S1236, Rennes, France

1:15 PM

Jinhua Liang, PhD1*, Yi-fan Wu, MD2*, Jun-heng Liang, MD3*, Yue Li2*, Xin-Yu Zhang, MD, PhD2*, Hao-Rui Shen2*, Jiazhu Wu4*, Liu qing Zhu, MD, PhD3*, Hua Yin4*, Li Wang4*, Jianyong Li, MD5 and Xu Wei, MD, PhD4

1Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, NANJING, China
2Department of Hematology, the First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
3Nanjing Geneseeq Technology Inc., Nanjing, China
4Department of Hematology, The First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China
5First Affiliated Hospital of Nanjing Medical University, Jiangsu Province Hospital, Nanjing, China

*signifies non-member of ASH