-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

618.O2.6 618. Acute Myeloid Leukemias: Biomarkers and Molecular Marker in Diagnosis and Prognosis: Deciphering the Mechanisms Underlying Prognosis

Symposia: Acute Myeloid Leukemias: Biomarkers and Molecular Markers in Diagnosis and Prognosis Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Acute Myeloid Malignancies, AML, Fundamental Science, Adult, Combination therapy, Translational Research, Elderly, Clinical Research, Genomics, Hematopoiesis, Diseases, Immune mechanism, Treatment Considerations, Immunology, Metabolism, Myeloid Malignancies, Biological Processes, Technology and Procedures, Molecular biology, Human, Study Population, Pathogenesis, Molecular testing, Omics technologies
Sunday, December 8, 2024: 4:30 PM-6:00 PM
Seaport Ballroom EFGH (Manchester Grand Hyatt San Diego)
Moderators:
Vanessa E. Kennedy, MD, University of California- San Francisco and Sarah Skuli, MD, PhD, Division of Hematology & Oncology, Department of Medicine, University of Pennsylvania
Disclosures:
No relevant conflicts of interest to declare.
4:30 PM

Susan DeWolf, MD1, Nicholas Ceglia, PhD2*, Matthew Zatzman, PhD3*, Brianna Gipson4*, Yuval Elhanati, PhD5*, Zoe Katsamakis6*, Hannah Lees, PhD3*, Kenyon Weis7*, Gustavo Yepes8*, Barbara Oliveira8*, Ana Figueiredo Longhini8*, Natalie Grier Smith, BA9*, Katherine Nichols4*, Eliyahu Havasov3*, Karen Zhao8*, Brigita Meskauskaite8*, Ignas Masilionis8*, Alexander M. Lewis7*, Maria Adriana Cuibus8*, M. Kazim Pajwani, PhD8*, Simone A Minnie, PhD10, Ronan Chaligne, PhD11*, Andri Leo L Lemarquis, MD, PhD4*, Aaron D. Goldberg12, Katharine C. Hsu, MD, PhD4, Eytan M. Stein, MD13, Benjamin D. Greenbaum, PhD3*, Omar Abdel-Wahab, MD1, Sohrab P. Shah, PhD2* and Marcel R.M. van den Brink, MD, PhD14

1Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY
2Computational Oncology, Memorial Sloan Kettering Cancer Center, New York, NY
3Computational Oncology, Memorial Sloan Kettering Cancer Center, New York
4Memorial Sloan Kettering Cancer Center, New York, NY
5Computational Oncology, Memorial Sloan-Kettering Cancer Center, New York, NY
6Department of Pediatrics, Immune Discovery and Modeling Service, Memorial Sloan Kettering Cancer Center, New York, NY
7Molecular Pharmacology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY
8Memorial Sloan Kettering Cancer Center, New York
9Department of Immunology, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY
10Translational Sciences and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA
11Single Cell Analytics and Innovation Lab, Memorial Sloan Kettering Cancer Center, New York, NY
12Department of Medicine; Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
13Department of Medicine; Leukemia Service, Memorial Sloan-Kettering Cancer Center, New York, NY
14Department of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA

4:45 PM

Logan K. Wallace, MSc1*, Jack H. Peplinski, MSc1*, Rhonda E. Ries, MA1*, Danielle C. Kirkey, MD1, Xiaotu Ma, PhD2 and Soheil Meshinchi, MD, PhD1,3

1Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle, WA
2St. Jude Children's Research Hospital, Memphis, TN
3Department of Pediatrics, University of Washington, Seattle, WA

5:00 PM

Yotaro Ochi, MD, PhD1,2*, Markus Liew-Littorin3*, Yasuhito Nannya1,4*, Sofia Bengtzén5*, Petar Antunovic6*, Stefan Deneberg, MD5*, Martin Jadersten, MD, PhD5*, Vladimir Lazarevic7,8*, Bertil Uggla3*, Lovisa Wennström, MD, PhD9*, Emma Olander10*, Senji Kasahara11*, Nobuhiro Hiramoto12*, Nobuhiro Kanemura, MD, PhD13, Nobuo Sezaki14*, Maki Sakurada15*, Makoto Iwasaki, MD, PhD15, Junya Kanda, MD, PhD15*, Yasunori Ueda16*, Satoshi Yoshihara, MD, PhD17, Tom Erkers18*, Nona Struyf18*, Masanori Motomura, MD1*, Masahiro M Nakagawa, MD, PhD1, Ryunosuke Saiki, MD, PhD1*, Hidehito Fukushima, MD4*, Koji Okazaki, MD1*, Akinori Yoda, PhD1*, Rurika Okuda, MSc, BS1*, Guoxiang Xie19*, Albin Osterroos, MD19*, Lanying Zhao, MD, PhD1*, Yuichi Shiraishi, PhD20*, Takayuki Ishikawa, MD, PhD12, Satoru Miyano, PhD21,22*, Hiroshi I Suzuki23,24,25,26*, Akifumi Takaori-Kondo, MD, PhD15, Olli Kallioniemi18*, Gunnar Juliusson, MD, PhD7,8, Martin Höglund, MD, PhD19, Soren Lehmann, MD, PhD5,19* and Seishi Ogawa, MD, PhD1,2,27

1Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
2Institute for the Advanced Study of Human Biology (WPI-ASHBi), Kyoto University, Kyoto, Japan
3Division of Hematology, Department of Medicine, Faculty of Medicine and Health, Örebro University, Örebro, Sweden
4Division of Hematopoietic Disease Control, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
5Center for Hematology and Regenerative Medicine, Department of Medicine Huddinge, Karolinska Institute, Stockholm, Sweden
6Department of Hematology, Linköping University Hospital, Linköping, Sweden
7Department of Hematology, Stem Cell Center, Department of Laboratory Medicine, Lund University, Lund, Sweden
8Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden
9Department of Hematology, Sahlgrenska University Hospital, Gothenburg, Sweden
10Department of Hematology, Sundsvall Hospital, Sundsvall, Sweden
11Department of Hematology, Gifu Municipal Hospital, Gifu, Japan
12Department of Hematology, Kobe City Medical Center General Hospital, Kobe, Japan
13Department of Hematology and Infectious Disease, Gifu University Hospital, Gifu, Japan
14Department of Hematology, Chugoku Central Hospital, Hiroshima, Japan
15Department of Hematology, Graduate School of Medicine, Kyoto University, Kyoto, Japan
16Department of Hematology/Oncology, Kurashiki Central Hospital, Kurashiki, Japan
17Department of Respiratory Medicine and Hematology, Hyogo Medical University, Nishinomiya, Japan
18Science for Life Laboratory and Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden
19Department of Medical Sciences, Hematology, Uppsala University, Uppsala, Sweden
20Division of Genome Analysis Platform Development, National Cancer Center Research Institute, Tokyo, Japan
21Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan
22Department of Integrated Analytics, M&D Data Science Center, Tokyo Medical and Dental University, Tokyo, Japan
23Division of Molecular Oncology, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan
24Institute for Glyco-core Research (iGCORE), Nagoya University, Nagoya, Japan
25Center for One Medicine Innovative Translational Research (COMIT), Nagoya University, Nagoya, Japan
26Inamori Research Institute for Science (InaRIS), Kyoto, Japan
27Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institute, Stockholm, Sweden

5:15 PM

Maddalena Benetton1*, Ambra Da Ros1*, Alberto Peloso1*, Giorgia Longo1*, Katia Polato1*, Sara Perpinello1*, Silvia Bresolin2*, Claudia Tregnago1*, Benjamin J Huang, MD3, Soheil Meshinchi, MD, PhD4, Franco Locatelli, MD5 and Martina Pigazzi, PhD1,2*

1Department of Women's and Children's Health, Onco-hematology lab and clinic, University of Padova, Padova, Italy
2Foundation Istituto Ricerca Pediatrica (IRP), Padova, Italy
3Department of Pediatrics, University of California, San Francisco, San Francisco, CA
4Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle, WA
5Department of Pediatric Hematology/Oncology, Cell and Gene Therapy, IRCCS Bambino Gesù Children’s Hospital, Catholic University of the Sacred Heart, Rome, Italy

5:30 PM

Lorenz Oelschläger1, Deedra Nicolet, MS2*, Krzysztof Mrózek, MD, PhD2, Daniel Schnell3*, Najla Alotaibi4*, Christopher J. Walker, PhD4, Alice Mims, MD4, James S. Blachly, MD4, Bayard L Powell, MD5, Jonathan E Kolitz, MD6, Eunice S. Wang, MD7, Andrew J. Carroll, PhD8, Lynn van Rosmalen9,10*, Bettina Nadorp, PhD11,12*, Nathan Salomonis, PhD3*, H. Leighton Grimes, PhD1, Maarten Fornerod, PhD9,13* and Ann-Kathrin Eisfeld, MD2

1Division of Immunobiology, Cincinnati Children's Hospital, Cincinnati, OH
2The Ohio State University Comprehensive Cancer Center, Columbus, OH
3Division of Biomedical Informatics, Cincinnati Children's Hospital, Cincinnati, OH
4Clara D. Bloomfield Center for Leukemia Outcomes Research, The Ohio State University Comprehensive Cancer Center, Columbus, OH
5Atrium Health Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, NC
6Zucker School of Medicine at Hofstra/Northwell, Zuckerberg Cancer Center, Lake Success, NY
7Leukemia Service, Department of Medicine, Roswell Park Comprehensive Cancer Center, Buffalo, NY
8Department of Genetics, University of Alabama at Birmingham, Birmingham, AL
9Department of Cell Biology, Erasmus Medical Center, Rotterdam, Netherlands
10Department of Pediatric Oncology Hematology, Erasmus Medical Center-Sophia Children's Hospital, Rotterdam, Netherlands
11NYU Grossman School of Medicine, Division of Precision Medicine, Department of Medicine, New York, NY
12NYU Grossman School of Medicine, Department of Pathology, New York, NY
13Department of Pediatric Oncology Hematology,, Erasmus Medical Center- Sophia Childrens Hospital, Rotterdam, ZH, NLD

5:45 PM

Sven Turkalj1*, Bilyana Stoilova, PhD2*, Angus J Groom, MSc2*, Felix A Radtke, MD2, Rabea Mecklenbrauck, MD2*, Niels Asger Jakobsen, MD, PhD2*, Curtis A Lachowiez, MD3, Marlen Metzner, MSc2*, Batchimeg Usukhbayar, PhD2*, Mirian Angulo Salazar, MSc2*, Zhihong Zeng, MD4, Sanam Loghavi, MD5, Jennifer Marvin-Peek, MD4, Verena Körber, PhD2*, Farhad Ravandi, MBBS6, Ghayas C. Issa, MD4, Tapan M. Kadia, MD4, Vasiliki Symeonidou, PhD2*, Anne De Groot, MSc2*, Hagop M. Kantarjian, MD4, Koichi Takahashi, MD, PhD4, Marina Konopleva7, Courtney D. DiNardo, MD, MSc4 and Paresh Vyas, FMedSci, DPhil, FRCPath2*

1MRC Molecular Haematology Unit, Radcliffe Department of Medicine, Weatherall Institute of Medicine, University of Oxford, Oxford, ENG, United Kingdom
2MRC Molecular Haematology Unit, Radcliffe Department of Medicine, Weatherall Institute of Medicine, University of Oxford, Oxford, United Kingdom
3Knight Cancer Institute, Oregon Health & Science University, Portland, OR
4Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
5Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
6Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
7Department of Oncology, Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, NY

*signifies non-member of ASH