-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

617.O2.3 617. Acute Myeloid Leukemias: Commercially Available Therapies: Impact of Molecularly-Targeted Agents in AML

Symposia: Acute Myeloid Leukemias: Commercially Available Therapies Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Acute Myeloid Malignancies, AML, Research, Clinical trials, Combination therapy, Apoptosis, Adult, Elderly, Drug development, Clinical Research, Chemotherapy, Diseases, Therapy sequence, Treatment Considerations, Biological therapies, Real-world evidence, Adverse Events, Non-Biological therapies, Young adult , Myeloid Malignancies, Biological Processes, Molecular biology, Study Population, Human, Measurable Residual Disease
Saturday, December 7, 2024: 2:00 PM-3:30 PM
Seaport Ballroom EFGH (Manchester Grand Hyatt San Diego)
Moderators:
Guillaume Richard-Carpentier, MD, FRCPC, and John L. Reagan, MD,
Disclosures:
Richard-Carpentier: AbbVie: Honoraria, Other: Advisory Board Participation; Astellas: Honoraria, Other: Advisory Board Participation; Pfizer: Honoraria, Other: Advisory Board Participation; Taiho: Honoraria, Other: Advisory Board Participation; BMS: Other: Advisory Board Participation. Reagan: Sanofi: Consultancy; Pfizer: Research Funding; Bristol Myers Squibb: Membership on an entity's Board of Directors or advisory committees.
2:00 PM

Chong Chyn Chua, MBBS, FRACP, FRCPA1,2,3, Blake Hsu4*, Anoop K Enjeti, MBBS, FRCPA, MD, MRCP5,6, Ashish Bajel, MBBS, FRACP, FRCPA7,8, Paula Marlton9*, Shaun Fleming, MBBS, FRACP, FRACPA10*, Devendra Hiwase, MD, MBBS, PhD, FRACP, FRCPA11, Chun Kei Kris Ma, BSc MBBS PhD FRACP FRCPA12, Peter J. Browett13, Travis Perera, MBChB14,15*, Carolyn S. Grove, MBBS, FRACP, FRCPA, PhD16, Shuhying Tan, FRACP, FRCPA, MBBS17*, Jad Othman, FRACP, FRCPA, MBBS18, Julian Cooney, FRACP, FRCPA, MBBS,19*, Hannah Rose20*, Edward S Morris21*, Rachel Koldej, PhD22,23, David S. Ritchie, MBChB PhD22,23,24, Kate Mason25*, Natasha S. Anstee, PhD2,26*, John Reynolds, BSc, MSc, PhD27,28* and Andrew H Wei, MBBS, PhD, FRACP, FRCPA2,24,29

1Monash Hospital and Monash University, Rosanna, VIC, Australia
2The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia
3Northern Hospital, Epping, VIC, Australia
4Department of Haematology, Christchurch Hospital, Christchurch, New Zealand
5Department of Haematology, Calvary Mater Hospital, Waratah, NSW, Australia
6School of Medicine and Public Health, College of Health, Medicine and Wellbeing, University of Newcastle, Newcastle, Australia
7Department of Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, VIC, Australia
8Department of Medicine, University of Melbourne, Melbourne, Australia
9Princess Alexandra Hospital and University of Queensland, Brisbane, QLD, Australia
10Department of Malignant Haematology & Stem Cell Transplantation, The Alfred Hospital, Melbourne, VIC, Australia
11Royal Adelaide Hospital, Adelaide, SA, Australia
12Westmead Hospital, Westmead, NSW, Australia
13Dept of Molecular Medicine and Pathology, Auckland Hospital and The University of Auckland School of Medicine, Auckland, New Zealand
14Te Rerenga Ora Wellington Blood & Cancer Centre, Te Whatu Ora Health New Zealand Capital Coast & Hutt Valley, Wellington, New Zealand
15Wellington Blood and Cancer Centre, Wellington Hospital, Wellington South, New Zealand
16Department of Haematology, Sir Charles Gairdner Hospital and PathWest, Perth, Australia
17Department of Haematology, St Vincent’s Hospital, Melbourne, Australia
18Royal North Shore Hospital, Redfern, NSW, Australia
19Fiona Stanley Hospital, Perth, Western Australia, Australia
20Department of Haematology, University Hospital Geelong, Geelong, Australia
21Department of Haematology, Townsville Hospital, Townsville, Australia
22Department of Medicine, The University of Melbourne, Melbourne, VIC, Australia
23ACRF Translational Research Laboratory, The Royal Melbourne Hospital, Parkville, VIC, Australia
24Department of Clinical Haematology, Peter MacCallum Cancer Centre and The Royal Melbourne Hospital, Melbourne, VIC, Australia
25Australasian Leukaemia Lymphoma Group, Melbourne, Australia
26Department of Medical Biology, The University of Melbourne, Melbourne, Australia
27Australian Centre for Blood Diseases, Monash University, Melbourne, Australia
28Department of Malignant Haematology, Transplantation and Cellular Therapy Services, Alfred Health, Melbourne, Australia
29The University of Melbourne, Melbourne, VIC, Australia

2:15 PM

Richard M Stone, MD1, Jun Yin2*, Sumithra J Mandrekar, PhD3*, Axel Benner4*, Maral Saadati4*, Ilene A. Galinsky, MSN, ANP-C1, Ben L. Sanford, MS5*, Rebecca Teske6*, Susan M. Geyer, PhD7, Thomas Prior, PhD8*, Sergio Amadori, MD9, Frederick R. Appelbaum, MD10, Joseph Brandwein, MD11, Konstanze Döhner, MD12, Gerhard Ehninger, M.D.13, Arnold Ganser, MD14, Rebecca B. Klisovic, MD15, Jürgen Krauter16*, Guido Marcucci17, Bruno Medeiros, MD18, Dietger W. Niederwieser, MD19, Miguel A. Sanz, MD, PhD20, Richard F. Schlenk, MD21*, Hubert Serve, MD22, Jorge Sierra, MD23, Martin S. Tallman, MD24, Andrew H Wei, MBBS, PhD, FRACP, FRCPA25, Theo J.M. de Witte, MD, PhD26, Christian Thiede, MD27, Hartmut Döhner, MD12 and Richard A. Larson, MD28

1Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
2Department of Biostatistics and Bioinformatics, HL Moffitt Cancer Center, Tampa, FL
3Mayo Clinic, Alliance Statistics and Data Management Center, Rochester, MN
4Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany
5Duke Cancer Institute, Durham, NC
6Division of Clinical Trials and Biostatistics, Mayo Clinic, Rochester, MN
7Alliance Statistics and Data Management Center, Mayo Clinic, Rochester, MN
8Johnson and Johnson, princeton, NJ
9Tor Vergata Polyclinic Hospital Rome, Rome, ITA
10Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA
11Department of Medicine, University of Alberta, Edmonton, AB, Canada
12Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany
13Department of Internal Medicine I, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, DEU
14Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany
15Department of Hematology and Stem Cell Transplant, University Hospitals Seidman Cancer Center, Cleveland, OH
16Department of Hematology and Oncology, Städtisches Klinikum Braunschweig, Braunschweig, Germany
17Gehr Family Center for Leukemia Research, City of Hope, Duarte, CA
18AbbVie, San Francisco
19Universitaetsklinikum Leipzig Aor, Leipzig, Germany
20Hospital Universitario y Politécnico La Fe, Valencia, Spain
21Department of Internal Medicine V, Heidelberg University Hospital, Heidelberg, Germany
22Department of Medicine, Hematology/Oncology, Goethe-University Frankfurt, University Hospital, Frankfurt am Main, Germany
23Hematology and Hemotherapy Department, Hospital de la Sant Creu i Sant Pau. IIB-Sant Pau and José Carreras Leukemia Research Institutes. Universitat Autónoma de Barcelona, Barcelona, Spain
24Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Highland Park, IL
25Peter MacCallum Cancer Centre, Melbourne, VIC, Australia
26Department of Tumor Immunology, Radboud Institute of Molecular Life Sciences, Radboud university medical centre, Nijmegen, NLD
27University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany
28Department of Medicine, Section of Hematology/Oncology, University of Chicago, Chicago, IL

2:30 PM

Jennifer Marvin-Peek, MD1, Jacqueline S. Garcia, MD2, Gautam Borthakur, MD3, Guillermo Garcia-Manero, MD1, Nicholas J. Short, MD1, Tapan M. Kadia, MD1, Sanam Loghavi, MD4, Lucia Masarova, MD1, Naval Daver, MD5, Abhishek Maiti, MBBS6, Koichi Takahashi, MD, PhD7, Koji Sasaki, MD1, Danielle Hammond, MD1, George Donovan Tippett, BS, BSN, RN1*, Dylan Wilson2*, Kelly S. Chien, MD8, Prithviraj Bose, MD9, Patrick K. Reville, MD, MPH1, Curtis A Lachowiez, MD10, Akriti G. Jain, MD11, Ghayas C. Issa, MD1, Nitin Jain, MD1, Guillermo Montalban-Bravo, MD1, Marlise R. Luskin, MD2, Hetty E. Carraway, MD, MBA11, Farhad Ravandi, MBBS12, Hagop M. Kantarjian, MD1 and Courtney D. DiNardo, MD, MSc1

1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
3Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
4Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
5MD Anderson Cancer Center, Houston, TX
6Department of Leukemia, The University of Texas Health Science Center At Houston, Houston, TX
7Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX
8Department of Leukemia, MD Anderson, Houston, TX
9The University of Texas MD Anderson Cancer Center, Houston, TX
10Knight Cancer Institute, Oregon Health & Science University, Houston, TX
11Department of Hematology and Medical Oncology, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH
12Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX

2:45 PM

Nicholas J. Short, MD1, Sanam Loghavi, MD2, Musa Yilmaz, MD1*, Omer Karrar3*, Joseph E. Jabbour4*, Courtney D. DiNardo, MD, MSc5, Tapan M. Kadia, MD1, Gautam Borthakur, MD6, Ghayas C. Issa, MD1, Hussein A. Abbas, MD, PhD1, Marina Konopleva7, Farhad Ravandi, MBBS8, Hagop M. Kantarjian, MD1 and Naval Daver, MD9

1Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
2Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
3The University of Texas MD Anderson Cancer Center, Houston, TX
4Department of Leukemi, The University of Texas MD Anderson Cancer Center, Houston, TX
5Department of Leukemia, UT MD Anderson Cancer Center, Houston, TX
6Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX
7Montefiore Einstein Comprehensive Cancer Center, Albert Einstein College of Medicine, Bronx, NY
8Department of Leukemia, University of Texas- MD Anderson Cancer Center, Houston, TX
9MD Anderson Cancer Center, Houston, TX

3:00 PM

Selina Luger, MD, FRCPC1, Li Chen, MS2*, Keith W. Pratz, MD3, Sanam Loghavi, MD4, Alexander E. Perl, MD5, Jessica K. Altman6*, Robert L. Redner, MD7, Amir T. Fathi, MD8, Ayman Qasrawi, MD9*, Adam S. Asch, MD10*, Deepa Jeyakumar, MD11, James M. Foran, MD12, Mithun V Shah, M.D., Ph.D.13, Jonathan E Kolitz, MD14, Ellin Berman, MD15, Lindsay Wilde, MD16, Sameem Abedin, MD17, Vamsi K. Kota, MD18, Krishna Gundabolu, MBBS, MS19*, Kristen M. O'Dwyer, MD20, Emily K Curran, MD21, Ashwin Kishtagari, MBBS22, Kelly Ross, MD23, Zhuoxin Sun, PhD24* and Mark R. Litzow, MD13

1Abramson Cancer Center, Hospital of the University of Pennsylvania, Philadelphia, PA
2Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
3Abramson Cancer Center, University of Pennsylvania, Philadelphia, PA
4Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX
5Division of Hematology-Oncology, Department of Medicine, University of Pennsylvania, Philadelphia, PA
6Robert H Lurie Comprehensive Cancer Center of Northwestern University, Northwestern Medical Group, Chicago, IL
7University of Pittsburgh Medical Center, Pittsburgh, PA
8Center for Leukemia, Massachusetts General Hospital Cancer Center, Boston, MA
9Department of Hematology, University of Kentucky, Lexington, KY
10Oklahoma University/Stephenson Cancer Center, Oklahoma City, OK
11Department of Medicine, Division of Hematology Oncology, Chao Family Comprehensive Cancer Center, University of California Irvine Health, University of California Irvine, Orange, CA
12Division of Hematology & Medical Oncology, Mayo Clinic, Jacksonville, FL
13Division of Hematology, Mayo Clinic, Rochester, MN
14Northwell Cancer Center, Hofstra/Northwell School of Medicine, Lake Success, NY
15Department of Medicine, Leukemia Service, Memorial Sloan Kettering Cancer Center, New York, NY
16Sidney Kimmel Comprehensive Cancer Center, Thomas Jefferson University, Philadelphia, PA
17Division of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI
18Georgia Cancer Center, Medical College of Georgia, Augusta University, Augusta, GA
19Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE
20University of Rochester, Rochester, NY
21Division of Hematology/Oncology, University of Cincinnati Cancer Center, Cincinnati, OH
22Department of Medicine, Division of Hematology and Oncology, Vanderbilt University Medical Center, Franklin, TN
23West Virginia University, Morgantown, WV
24Dana-Farber Cancer Institute, Boston, MA

3:15 PM

Xueqing Dou1,2,3*, Suning Chen4,5,6* and Depei Wu, MD, PhD7,8,9

1National Clinical Research Center for Hematologic Diseases, Jiangsu Institute of Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China
2National Clinical Research Center For Hematologic Diseases, Jiangsu Institute of, Suzhou, China
3The first Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, National Clinical Research Center of Hematologic Diseases, Suzhou, China
4The First Affiliated Hospital of Soochow University, Suzhou, China
5Jiangsu Institute of Hematology, the First Affiliated Hospital of Soochow University, Suzhou, China
6National Clinical Research Center for Hematologic Diseases, The First Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China
7Institute of Blood and Marrow Transplantation, Collaborative Innovation Center of Hematology, Soochow University, Suzhou, China
8National Clinical Research Center For Hematologic Diseases, Jiangsu Institute of, Suzhou, CHN
9the Leukemia Working Group of National Clinical Research Center for Hematologic Diseases, Suzhou, China

*signifies non-member of ASH