Jessica A. Pollard, MD¹, Todd A. Alonzo, PhD^2*, Robert Gerbing, MS^3*, Matthew A. Kutny, MD⁴, Betsy Hirsch, PhD^5*, Gordana Raca, MD, PhD⁶, Kasey Leger, MD, MSc⁷, Jennifer J. Wilkes, MD, MSCE⁸, Aman Wadhwa, MD⁹, Zachary Graff, MD¹⁰, Reena Pabari, MD, MSc, FRCPC^11*, Samir Kahwash, MD^12*, Karen M Chisholm, MD, PhD¹³, Joseph Chewning, MD¹⁴, John T. Horan, MD¹⁵, Richard Aplenc¹⁶, Katherine Tarlock, MD¹⁷, Sarah Menig, PharmD, BCOP^18*, Olga Militano, PharmD^19*, Bonnie Ky, MD^20*, Chad A. Hudson, MD, PhD²¹, Lisa Eidenschink Brodersen, PhD^16*, Michael R. Loken, PhD^21*, Soheil Meshinchi, MD, PhD²², Anders Kolb, MD²³ and Todd M Cooper, DO²⁴

¹Dana Farber Cancer Institute and Boston Children’s Hospital, Boston, MA
²Univ. of Southern California Keck School of Med., Monrovia, CA
³Children's Oncology Group, Arcadia, CA
⁴University of Alabama Birmingham, Birmingham, AL
⁵University of Minnesota, Minneapolis, MN
⁶Pathology and Laboratory Medicine, Children's Hospital Los Angeles, Los Angeles, CA
⁷Seattle Children’s Hospital, Seattle, WA
⁸Pediatrics, University of Washington School of Medicine, Seattle, WA
⁹Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham, AL
¹⁰Medical College of Wisconsin, Milwaukee, WI
¹¹The Hospital for Sick Children, Toronto, ON, Canada
¹²Nationwide Children's Hospital, The Ohio State University, Columbus, OH
¹³University of Washington, Seattle, WA
¹⁴Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL
¹⁵University of Rochester Medical Center, Rochestser
¹⁶Children's Hospital of Philadelphia, Philadelphia, PA
¹⁷Division of Pediatric Hematology, Oncology, Bone Marrow Transplant & Cellular Therapy, Seattle Children's Hospital, Seattle, WA
¹⁸Cancer and Blood Disorders Center, Seattle Children's Hospital, Seattle, WA
¹⁹Children's Oncology Group, Monrovia, CA
²⁰University of Pennsylvania School of Medicine, Philadelphia, PA
²¹Hematologics, Inc., Seattle, WA
²²Translational Science and Therapeutics, Fred Hutchinson Cancer Center, Seattle, WA
²³Leukemia & Lymphoma Society, Bronx, NY
²⁴Division of Pediatric Hematology, Oncology, Bone Marrow Transplant & Cellular Therapy, Seattle Childrens Hospital, Seattle, WA

Brenda Gibson, MD^1*, Andre Baruchel, MD^2*, Andrew Moore, MBBS, PhD, FRACP^3*, Shanna Maycock, MSc^4*, Owen Smith, MD^5*, Geoff Shenton^6*, Jean-Pierre Bourquin, MD, PhD⁷, Yves Bertrand, MD^8*, Nicholas Heaney^1*, Anna Lawson, BSc^9*, Persis Jal Amrolia^10*, Gerard Michel, MD, PhD^11*, Jean-Hugues Dalle, MD, PHD¹², Marc Ansari, MD, PhD¹³, Hélène Lapillonne, MD, PhD^14*, Richard Dillon, MA¹⁵, Jelena Jovanovic, PhD^16*, Siobhan Cross, MD^17*, Paul Virgo^18*, Lucy Wheeler^19*, Christophe Roumier, PharmD^20*, Nicolas Duployez, PharmD, PhD^21*, Christine Harrison, PhD, FRCPath^22*, Claire Schwab, PhD^22*, Wendy Cuccuini, MD, PhD^23*, Marina Lafage-Pochitaloff, MD, PhD^24*, Claude Preudhomme, PharmD, PhD^25*, Paresh Vyas, FMedSci, DPhil, FRCPath^26*, Pierre Hirsch, MD, PhD^27*, Gareth Veal, PhD^22*, David Gillis, MBBS, FRACP, FRCPA^28*, Pam Kearns, MBChB, PhD, FRCPC^9*, Guy Leverger, MD, PhD^29*, Phil Ancliff^30*, Aimee Jackson, BSc MSc^31* and Arnaud Petit, MD, PhD^32*

¹Royal Hospital for Children, Glasgow, Glasgow, United Kingdom
²Hôpital Universitaire Robert Debré (APHP and Université Paris Cité), Paris, France
³Child Health Research Centre, The University of Queensland, South Brisbane, QLD, Australia
⁴Cancer Research UK Clinical Trials Unit, University of Birmingham, Edgbaston, United Kingdom
⁵Children's Health Ireland, Dublin, Ireland
⁶Great North Children’s Hospital, Newcastle, United Kingdom
⁷Department of Pediatric Oncology, University Children's Hospital Zurich, Zurich, Switzerland
⁸Pediatric Hematology, Institut d'Hématologie et Oncologie Pédiatrique, Lyon, France
⁹Cancer Research UK Clinical Trials Unit, University of Birmingham, Birmingham, United Kingdom
¹⁰Bone Marrow Transplant Department, Great Ormond Street Hospital, London, United Kingdom
¹¹CHU de Marseille Hôpital de la Timone Enfants, Marseille, France
¹²Department of Pediatric Hematology and Immunology, Robert-Debré Academic Hospital ,, Assistance Publique des Hôpitaux de Paris (APHP), Paris, France
¹³Department of Pediatrics, Onco-Hematology Unit,, Geneva University Hospital, Geneva, Switzerland
¹⁴Laboratory of Hematology and Flow cytometry, Trousseau Hospital, Paris, France
¹⁵Guy's and St. Thomas' NHS Foundation Trust, London, ENG, United Kingdom
¹⁶King’s College London, London, United Kingdom
¹⁷Christchurch Hospital, Christchurch, NZL
¹⁸Southmead Hospital, Bristol, GBR
¹⁹Southmead Hospital, North Bristol NHS Trust, Bristol, United Kingdom
²⁰ONCOLILLE - CANTHER - Cancer Heterogeneity Plasticity and Resistance to Therapies, Centre Hospitalier Universitaire (CHU) de Lille, Lille, France
²¹Laboratory of Hematology-Molecular Biology, Centre Hospitalier Universitaire (CHU) de Lille, Lille, France
²²Newcastle University, Newcastle, United Kingdom
²³Saint Louis Hospital, Paris, France
²⁴CHU Timone Enfants, Marseille, France
²⁵Laboratory of Hematology-Molecular Biology, CHU Lille, Lille, France
²⁶Department of Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom
²⁷Hematology Laboratory, Saint Antoine University Hospital, AP-HP, Paris, France
²⁸Royal Brisbane and Women's Hospital, Brisbane, Australia
²⁹Pediatric Hematology Oncology Immunology Department, Hôpital Trousseau, Paris, France
³⁰Department of Haematology, Great Ormond Street Hospital for Children, London, United Kingdom
³¹Cancer Research UK Trials Unit, University of Birmingham, Birmingham, United Kingdom
³²Hôpital Armand Trousseau, APHP, PARIS, Île-de-France, France

Justin M. Watts, MD¹, Connor Sohalski^2*, Alessia Zoso, PhD^3*, Jessica Dell-Martin^4*, Ayele Belachew^5*, Diana Abbott, PhD⁶, Maria L Amaya, MD, PhD^2,7, Andrew Kent, MD, PhD⁵, Christine M. McMahon, MD⁸, Marc Schwartz, MD^5,9, Mikkael A. Sekeres, MD^10,11, Clayton Smith, MD¹², Sangeetha Venugopal, MD, MS¹¹, Craig T Jordan, PhD¹³, Mary Berg, MD^14*, Mary Haag^15*, Nicholas Willard^16*, Dara Aisner^2*, Jeffrey Schowinsky^2*, Zenggang Pan, MD, PhD^17*, Jingjing Zhang^2*, Jonathan Gutman, MD⁵ and Daniel A Pollyea, MD⁹

¹Sylvester Cancer Center, University of Miami Miller School of Medicine, Miami, FL
²University of Colorado, Aurora, CO
³University of Miami Sylvester Cancer Center, Miami, FL
⁴University of Colorado Anschutz Medical Campus, Aurora, CO
⁵Division of Hematology, University of Colorado, Aurora, CO
⁶Center for Innovative Design and Analysis (CIDA), Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado, Anschutz Medical Campus, Aurora, CO
⁷Rocky Mountain Regional VA Medical Center, Aurora, CO
⁸University of Colorado School of Medicine, Denver, CO
⁹Division of Hematology, University of Colorado, Denver, CO
¹⁰Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL
¹¹Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL
¹²CU Innovations, University of Colorado, Aurora, CO
¹³Division of Hematology, University of Colorado Anschutz Medical Campus, Aurora, CO
¹⁴University of Colorado Program, Aurora, CO
¹⁵University of Colorado, Aurora
¹⁶University of Colorado Children's Hospital, Aurora
¹⁷Department of Pathology, University of Colorado Anschutz Medical Campus, Aurora, CO

Agnieszka Wierzbowska^1,2, Agnieszka Pluta^1,2*, Anna Czyz^3*, Marta Libura^4*, Sebastian Giebel, MD, PhD^5*, Michał Soin^1*, Damian Mikulski^6,7*, Kacper Kościelny^6*, Wojciech Fendler^6*, Magdalena Czemerska^1,2*, Agata Majchrzak^2*, Anna Kopinska^8*, Krzysztof Woźniczka^8*, Martyna Włodarczyk^1*, Karol Wójcik^9*, Grzegorz Helbig^8*, Małgorzata Raźny^9*, Marta Sobas, MD^10*, Tomasz Wróbel, MD, PhD^10*, Donata Szymczak^10*, Andrzej Szczepaniak, MD^11*, Lidia Gil, MD, PhD¹², Magdalena Dutka^13*, Maria Bieniaszewska^14*, Tomasz Gromek^15*, Marek Hus, MD, PhD^16*, Edyta Cichocka^17*, Janusz Hałka^18*, Elzbieta Patkowska^19*, Marzena Wątek^19*, Jolanta Wozniak^19*, Ewa Lech-Maranda, MD, PhD^19*, Agata Obara^20*, Agnieszka Kopacz^21*, Katarzyna Dulik^5*, Grzegorz Charlinski^17*, Jerzy Holowiecki^5*, Andi Rustani^22*, Ameenah Sukkur^22*, Nuria Mencia-Trinchant^22*, Pinkal Desai²³, Michael Samuel^22*, Justin D. Kaner, MD²⁴, Michal Bar-Natan, MD²², Jonathan Canaani, MD²⁵, Ellen K. Ritchie, MD²², Monica L Guzman, PhD²², Sylvie D Freeman²⁶ and Gail J. Roboz, MD²²

¹Department of Hematology, Medical University of Lodz, Lodz, Poland
²Department of Hematology and Transplantology, Multidisciplinary Provincial Centre of Traumatology and Oncology Nicolas Copernicus in Lodz, Lodz, Poland
³Deaprtment of Hematology, Medical University of Wroclaw, Wroclaw, Poland
⁴Department of Hematology, Transplantation and Internal Medicine, Medical University of Warsaw, Warsaw, Poland
⁵Department of Hematology and Bone Marrow Transplantation, Maria Sklodowska-Curie Institute of Oncology, Gliwice, Poland
⁶Department of Biostatistics and Translational Medicine, Medical University of Lodz, Lodz, Poland
⁷Department of Hematooncology, Multidisciplinary Provincial Centre of Traumatology and Oncology Nicolas Copernicus in Lodz, Lodz, Poland
⁸Department of Hematology, Medical University of Silesia, Katowice, Poland
⁹Department of Hematology, Municipial Specialist Hospital, Cracow, Poland
¹⁰Department of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Medical University of Wroclaw, Wroclaw, Poland
¹¹Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland
¹²Department of Hematology, Medical University of Poznań, Poznan, Poland
¹³Department of Hematology and Transplantology, Medical University of Gdansk and University Clinical Center in Gdansk, Gdansk, Poland
¹⁴Department of Hematology, Medical University of Gdańsk, Gdansk, Poland
¹⁵Department of Hematology, Medical University of Lublin, Lublin, Poland
¹⁶Medical University of Lublin, Lublin, Poland
¹⁷Department of Hematology, Nicolaus Copernicus Municipal Specialist Hospital, Torun, Poland
¹⁸Department of Hematology, Municipal Specialist Hospital, Olsztyn, Poland
¹⁹Department of Hematology, Institute of Hematology and Transfusion Medicine, Warsaw, Poland
²⁰Department of Hematology, Holly Cross Oncology Center, Kielce, Poland
²¹Department of Hematology, Voivodeship Specialistic Hospital in Rzeszów, Rzeszow, Poland
²²Weill Cornell Medicine and The New York Presbyterian Hospital in New York City, New York, NY
²³Weill Cornell Medicine New York Presbyterian Hospital, New York, NY
²⁴New York-Presbyterian/Weill Cornell Medical Center, New York, NY
²⁵Weill Cornell Medicine and The New York Presbyterian Hospital in New York City, Brooklyn, NY
²⁶Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom

Jing Lu, MD^1*, Shengli Xue^1*, Ying Wang^1*, Xuefeng He, MD, PhD^2,3*, Xiaohui Hu^1*, Miao Miao, MD^1*, Yang Zhang^4*, Zaixiang Tang^5*, Jundan Xie^1*, Xiaofei Yang^1*, Mingzhu Xu^1*, Yaoyao Shen^1*, Feng Du^2*, Qian Vicky Wu^1*, Mengxing Xue^1*, Yun Wang^1*, Ailing Deng^1*, Xueqing Dou^1*, Haiping Dai^1*, Depei Wu, MD, PhD⁶ and Suning Chen, MD, PhD^1*

¹The first Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, National Clinical Research Center of Hematologic Diseases, Suzhou, China
²Soochow Hopes Hematonosis Hospital, Suzhou, China
³Hematology, The First Affiliated Hospital of Soochow University, Suzhou, China
⁴Canglang Hospital of Suzhou, Suzhou, China
⁵Department of Biostatistics, Soochow University, Suzhou, CHN
⁶Department of Hematology, The first Affiliated Hospital of Soochow University, Jiangsu Institute of Hematology, National Clinical Research Center of Hematologic Diseases, Suzhou, China

Zinan Feng^*, Yu Zhang, MD^*, Hui Liu^*, Sijian Yu^*, Qifa Liu, MD and Li Xuan^*

Department of Hematology, Nanfang Hospital, Southern Medical University, Guangzhou, China