Irene Navarro Vicente, MD^1,2*, Antonio Solana-Altabella, PharmD^1,3*, Marta Sobas, MD^4*, Josefina Serrano, MD^5*, Magdalena Karasek, MD^6*, Manuel Perez Encinas, MD^7*, Jorge Labrador, MD^8,9*, Cristina de la Fuente, MD^10*, Olga Salamero, MD^11*, Rafael Colmenares Gil^12*, Tamara Castaño, MD^13*, Jesús Lorenzo Algarra, MD^14*, María García-Fortes, MD^15*, Maria Dunia De Miguel, MD^16*, Fernanda Trigo, MD^17*, Delfim Duarte, MD, PhD¹⁸, Virginia Pradillo Fernandez, MD^19*, Maria Angeles Foncillas, MD^20*, Victor Noriega Concepcion, MD^21*, Pedro Paúl Vidaller, MD^22*, Teresa Bernal Del Castillo, MD, PhD^23,24,25*, Juan Miguel Bergua Burgues, MD^26*, Gabriela Rodriguez Macias, MD²⁷, Eduardo Rodriguez Arboli, MD MPhil^28*, Isabel Simon, MD^29,30*, Nerea Caminos, MD^31*, Ada Esteban-Figuerola, MD^32*, Joana Brioso Infante, MD, MSc^33,34*, Monica Alejandra Romero, MD^35*, Rolando Omar Vallansot, MD^36*, Lukasz Targonski, MD^37*, Emilia Ulenberg, MD^38*, Krzysztof Lewandowski, MD^39*, Anna Armatys, MD^40*, Renata Guzicka-Kazmierczak, MD, PhD^41*, Małgorzata Sobczyk-Kruszelnicka, MD^42*, Andrzej Szczepaniak, MD^43*, Beatriz De Rueda Ciller, MD^44*, Esperanza Lavilla, MD^45*, Maria Paz Garrastazul Sánchez, MD^46*, Jackeline Solano Tovar, MD^47*, Cristina Insua Vilas, MD^48*, Maria Dolores Madrigal Toscano, MD^49*, Laura Lamarca, MD^50*, Mar Tormo, MD^51,52, Cristina Gil, MD^53*, Mercedes Colorado, MD^54,55*, Manuel Barrios García, MD, PhD^56*, Matxalen Olivares Salaverri, MD^57*, Lisette Costilla-Barriga, MD^58*, Rebeca Rodriguez Veiga, MD, PhD^1,2*, Pilar Lloret Madrid, MD^2*, David Martinez Cuadron, MD, PhD^1,2* and Pau Montesinos, PhD, MD^1,2,59*

¹Department of Hematology, Instituto de Investigación Sanitaria La Fe (IISLAFE), Valencia, Spain
²Department of Hematology, Hospital Universitari i Politècnic La Fe, Valencia, Spain
³Department of Pharmacy, Hospital Universitari i Politècnic La Fe, Valencia, Spain
⁴Department of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Medical University of Wroclaw, Wroclaw, Poland
⁵Department of Hematology, Hospital Universitario Reina Sofía, IMIBIC.UCO, Cordoba, ESP
⁶Department of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland
⁷Department of Hematology, Hospital Unviersitario de Santiago de Compostela, IDIS, Santiago de Compostela, ESP
⁸Department of Hematology-Hospital Universitario Burgos, Burgos, Spain
⁹Research Unit. Hospital Universitario de Burgos, Burgos, Spain
¹⁰Department of Hematology, Institut Català d'Oncologia, Hospital Germans Trias i Pujol, Barcelona, Spain
¹¹Department of Hematology, University Hospital Vall d’Hebron, University Autonoma of Barcelona (UAB),, Barcelona, Spain
¹²Hospital Universitario 12 de Octubre, Madrid, Spain
¹³Department of Hematology, Hospital Fundación Jiménez Díaz, Madrid, Spain
¹⁴Hospital General de Albacete, Albacete, Spain
¹⁵Department of Hematology, Hospital Universitario Virgen De La Victoria, Málaga, Spain
¹⁶Department of Hematology, Hospital Universitario de Guadalajara, Guadalajara, ESP
¹⁷Department of Clinical Hematology, Hospital S João-Porto, Porto, Portugal
¹⁸Hematology Department, Inst. Português Oncología do Porto Francisco Gentil, Oporto, Portugal
¹⁹Department of Hematology., Hospital Universitario Quirónsalud, Madrid, Spain
²⁰Department of Hematology, Hospital Universitario Infanta Leonor, Madrid, ESP
²¹Hospital Universitario de A Coruña, A Coruña, ESP
²²Hematology Department, Hosp. Clínico Univ. Lozano Blesa, Zaragoza, Spain
²³Hospital Universitario Central de Asturias, ISPA, IUOPA, Oviedo, Spain
²⁴Hospital Universitario Central de Asturias, Oviedo, Spain
²⁵Department of Hematology, Hospital Universitario Central de Asturias, Instituto Universitario (IUOPA), Instituto de Investigación del Principado de Asturias (ISPA), Oviedo, Spain
²⁶Hospital San Pedro de Alcántara, Caceres, Spain
²⁷Department of Hematology, Hospital Universitario Gregorio Maranon, Madrid, Spain
²⁸Department of Hematology, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla (IBIS/CSIC), University of Seville, Sevilla, Spain
²⁹Department of Hematology, Hospital Virgen de Valme, Sevilla, ESP
³⁰Hematology Department, Hosp. Virgen de Valme, Sevilla, Spain
³¹Hospital Universitario De Donostia, Donostia-San Sebastián, ESP
³²Hospital San Pedro, Logroño, ESP
³³Hematology Department, Centro Hospitalar Universitario Lisboa Norte - Hospital de Santa Maria, Lisboa, Portugal
³⁴Faculdade de Medicina da Universidade de Lisboa., Lisboa, Portugal
³⁵Hematology Division, Hospital Guillermo Grant Benavente, Concepcion, CHL
³⁶Department of Hematology, Hospital Universitari Joan XXIII. ICO-Tarragona, Tarragona, Spain
³⁷National Research Institute of Oncology, Warsaw, Poland
³⁸Department of Laboratory Medicine, Medical University of Gdansk, Gdansk, Poland
³⁹Department of Hematology and Transplantology, Medical University of Gdansk, Gdansk, Poland
⁴⁰Department of Hematology and Transplantology, Medical University in Katowice, Katowice, Poland
⁴¹Department of Hematology and Transplantology, Medical University in Szczecin, Szczecin, Poland
⁴²National Research Institute of Oncology, Gliwice, Poland
⁴³Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland
⁴⁴Department of Hematology, Hospital Universitario Miguel Servet, Zaragoza, Spain
⁴⁵Servicio de Hematología. Hospital Universitario Lucus Augusti, Lugo, Spain
⁴⁶Hospital Universitario Puerta del Mar, Cádiz, Spain
⁴⁷Department of Hematology, Hospital Rio Carrión - Complejo Asistencial de Palencia, Palencia, Spain
⁴⁸Hematology Department. Hospital POVISA, Lugo, Spain
⁴⁹Hospital Universitario Virgen Macarena, Sevilla, ESP
⁵⁰Hematology Department. Hospital Santa Ana De Motril, Motril, Spain
⁵¹Department of Hematology and Medical Oncology,, Hospital Clínico Universitario de Valencia. INCLIVA Biomedical Research Institute, Valencia, Spain
⁵²INCLIVA Research Institute, University Clinical Hospital, Valencia, Spain
⁵³Hospital General Universitario de Alicante, Alicante, ESP
⁵⁴Hematology Department, Hospital Universitario Marqués de Valdecilla, Santander, Spain
⁵⁵PETHEMA Group. Spanish Society of Hematology, Badalona, Spain
⁵⁶Department of Hematology, Hospital Regional Universitario de Málaga, Málaga, Spain
⁵⁷Hematology Department, Hospital Universitario Galdakao Usándolo, Bizkaia, Spain
⁵⁸Hospital San Jorge, Zaragoza, ESP
⁵⁹Programa Español de Tratamientos en Hematologia, PETHEMA, Valencia, Spain

Antonio Solana-Altabella, PharmD^1,2*, Irene Navarro Vicente^1,3*, Marta Sobas, MD^4*, Josefina Serrano, MD^5*, Magdalena Karasek, MD^6*, Manuel Perez Encinas, MD^7*, Jorge Labrador, MD^8*, Cristina de la Fuente, MD^9*, Olga Salamero, MD^10*, Rafael Colmenares^11*, Tamara Castaño, MD^12*, Lorenzo Algarra, MD^13*, María García-Fortes, MD^14*, Maria Dunia De Miguel, MD^15*, Fernanda Trigo, MD^16*, Delfim Duarte, MD, PhD¹⁷, Virginia Pradillo Fernandez, MD^18*, Maria Angeles Foncillas, MD^19*, Victor Noriega Concepción, MD^20*, Pedro Paúl Vidaller, MD^21*, Teresa Bernal Del Castillo, MD, PhD^22*, Juan Miguel Miguel Bergua Burgues^23*, Gabriela Rodriguez Macias, MD²⁴, Eduardo Rodriguez Arboli, MD MPhil^25*, Isabel Simon, MD^26*, Nerea Caminos, MD^27*, Ada Esteban-Figuerola, MD^28*, Joana Brioso Infante, MD, MSc^29*, Monica Alejandra Romero, MD^30*, Rolando Omar Vallansot, MD^31*, Lukasz Targonski, MD^32*, Emilia Ulenberg, MD^33*, Krzysztof Lewandowski, MD^34*, Anna Armatys, MD^35*, Renata Guzicka-Kazmierczak, MD, PhD^36*, Małgorzata Sobczyk-Kruszelnicka, MD^37*, Andrzej Szczepaniak, MD^38*, Beatriz De Rueda Ciller, MD^39*, Esperanza Lavilla-Rubira, MD^40*, Maria Paz Garrastazul Sánchez, MD^41*, Jackeline Solano Tovar, MD^42*, Cristina Insua Vilas, MD^43*, Maria Dolores Madrigal, MD^44*, Laura Lamarca Eraso, MD^45*, Mar Tormo, MD⁴⁶, Carmen Botella, MD, PhD^47*, Mercedes Colorado, MD^48*, Manuel Barrios García, MD, PhD^49*, Rebeca Rodriguez-Veiga, MD, PhD^3,50*, Pilar Lloret Madrid, MD^3*, David Martinez Cuadron, MD, PhD^1,3* and Pau Montesinos, PhD, MD^3*

¹Department of Hematology, Instituto de Investigación Sanitaria La Fe (IISLAFE), Valencia, Spain
²Department of Pharmacy, Hospital Universitari i Politècnic La Fe, Valencia, Spain
³Department of Hematology, Hospital Universitari i Politècnic La Fe, Valencia, Spain
⁴Department of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Medical University of Wroclaw, Wroclaw, Poland
⁵Department of Hematology, Hospital Universitario Reina Sofía, IMIBIC.UCO, Cordoba, ESP
⁶Department of Hematology, Blood Neoplasms and Bone Marrow Transplantation, Wroclaw Medical University, Wroclaw, Poland
⁷Department of Hematology, Hospital Unviersitario de Santiago de Compostela, IDIS, Santiago de Compostela, ESP
⁸Department of Hematology, Hospital Universitario de Burgos, Universidad Isabel I, Burgos, Spain
⁹Department of Hematology, Institut Català d’Oncologia - Hospital Universitari Germans Trias i Pujol, Institut de Recerca Contra la Leucèmia Josep Carreras, Universitat Autònoma de Barcelona, Badalona, Spain
¹⁰Hematology Department, Vall d'Hebron University Hospital, University Autònoma of Barcelona (UAB), Barcelona, Spain
¹¹Department of Hematology, Hospital Universitario 12 de Octubre, Madrid, Spain
¹²Department of Hematology, Hospital Fundación Jiménez Díaz, Madrid, Spain
¹³Department of Hematology, Hospital General de Albacete, Albacete, Spain
¹⁴Department of Hematology, Hospital Universitario Virgen De La Victoria, Málaga, Spain
¹⁵Department of Hematology, Hospital Universitario de Guadalajara, Guadalajara, ESP
¹⁶Department of Clinical Hematology, Hospital S João-Porto, Porto, Portugal
¹⁷Department of Hematology, Instituto Português Oncología do Porto Francisco Gentil, Porto, Portugal
¹⁸Department of Hematology., Hospital Universitario Quirónsalud, Madrid, Spain
¹⁹Department of Hematology, Hospital Universitario Infanta Leonor, Madrid, ESP
²⁰Complejo Hospitalario Universitario de A Coruña, A Coruña, ESP
²¹Department of Hematology, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain
²²Department of Hematology, Hospital Universitario Central de Asturias, Instituto Universitario (IUOPA), Instituto de Investigación del Principado de Asturias (ISPA), Oviedo, Spain
²³Department of Hematology, Hospital San Pedro de Alcántara, Caceres, Spain
²⁴Department of Hematology, Hospital Universitario Gregorio Maranon, Madrid, Spain
²⁵Department of Hematology, Hospital Universitario Virgen del Rocío, Instituto de Biomedicina de Sevilla (IBIS/CSIC), University of Seville, Sevilla, Spain
²⁶Department of Hematology, Hospital Virgen de Valme, Sevilla, ESP
²⁷Hospital Universitario De Donostia, Donostia-San Sebastián, ESP
²⁸Hospital San Pedro, Logroño, ESP
²⁹Department of Hematology, Centro Hospitalar Universitario Lisboa Norte - Hospital de Santa Maria, Lisboa, Portugal
³⁰Hematology Division, Hospital Guillermo Grant Benavente, Concepcion, CHL
³¹Department of Hematology, Hospital Universitari Joan XXIII. ICO-Tarragona, Tarragona, Spain
³²National Research Institute of Oncology, Warsaw, Poland
³³Department of Laboratory Medicine, Medical University of Gdansk, Gdansk, Poland
³⁴Department of Hematology and Transplantology, Medical University of Gdansk, Gdansk, Poland
³⁵Department of Hematology and Transplantology, Medical University in Katowice, Katowice, Poland
³⁶Department of Hematology and Transplantology, Medical University in Szczecin, Szczecin, Poland
³⁷National Research Institute of Oncology, Gliwice, Poland
³⁸Department of Hematology and Bone Marrow Transplantation, Poznan University of Medical Sciences, Poznan, Poland
³⁹Department of Hematology, Hospital Universitario Miguel Servet, Zaragoza, Spain
⁴⁰Hospital Universitario Lucus Agusti, Lugo, Spain
⁴¹Hospital Universitario Puerta del Mar, Cádiz, Spain
⁴²Department of Hematology, Hospital Rio Carrión - Complejo Asistencial de Palencia, Palencia, Spain
⁴³Department of Hematology, Hospital Povisa, VIgo, Spain
⁴⁴Department of Hematology, Hospital Universitario Virgen Macarena, Sevilla, ESP
⁴⁵Department of Hematology, Hospital Santa Ana de Motril, Motril, Spain
⁴⁶Department of Hematology and Medical Oncology,, Hospital Clínico Universitario de Valencia. INCLIVA Biomedical Research Institute, Valencia, Spain
⁴⁷Department of Hematology, Hospital General Universitario De Alicante, Alicante, Spain
⁴⁸Department of Hematology, Hospital Universitario Marqués De Valdecilla, Santander, Spain
⁴⁹Department of Hematology, Hospital Regional Universitario de Málaga, Málaga, Spain
⁵⁰Department of Hematology, Instituto de Investigación Sanitaria La Fe, Valencia, Spain

Shai Shimony, MD¹, Julia Keating, MS^2*, Marlise R. Luskin, MD¹, Christopher Fay^3*, Florian Renosi^4,5*, Eric Deconinck^4,5, Francine Garnache-Ottou^4,5*, Donna S. Neuberg, ScD², Nicole R. Leboeuf^3* and Andrew A. Lane, MD, PhD¹

¹Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA
²Department of Data Science, Dana-Farber Cancer Institute, Boston, MA
³Dermatology, Brigham and Women Hospital, Boston, MA
⁴Université de Franche-Comté, EFS, INSERM, UMR RIGHT, Besançon, France
⁵CHU Besançon, Besançon, France

Kristian Juul Sandahl, MD^1*, Kristian Juul-Dam, MD^2*, Morten Krogh Herlin^3*, Jonas Abrahamsson, MD, PhD, Professor^4*, Nira Arad-Cohen^5*, Daniel Cheuk^6*, Barbara De Moerloose, MD, PhD^7*, Jose Maria Fernandez Navarro^8*, Linda Fogelstrand, MD⁹, Kirsi Jahnukainen^10*, Gertjan J.L. Kaspers, MD, PhD¹¹, Zhanna Kovalova^12*, Monica Cheng Munthe-Kaas^13*, Ulrika Norén-Nyström, MD, PhD^14*, Josefine Palle^15*, Ramune Pasauliene^16*, Cornelis Jan Pronk, MD, PhD^17*, Kadri Saks^18*, Eigil Kjeldsen, Professor^19* and Henrik Hasle²

¹Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Aarhus N, Denmark
²Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark
³Department of Genetics, Aarhus University Hospital, Aarhus, Denmark
⁴Department of Pediatrics, Institute for Clinical Sciences, University of Gothenburg, Gothenburg, Sweden
⁵Department of Pediatric Hemato-Oncology, Rambam Health Care Campus, Haifa, Israel
⁶Department of Pediatrics and Adolescent Medicine, Hong Kong Children's Hospital and Hong Kong Pediatric Hematology and Oncology Study Group (HKPHOSG), Hong Kong, China
⁷Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium
⁸Department of Pediatric Hemato-Oncology, Hospital Universitario y Politécnico La Fe, Valencia, Spain
⁹Region Vastra Gotaland, Sahlgrenska University Hospital, Gothenburg, Sweden
¹⁰New Children's Hospital, Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
¹¹VU University Medical Center, Utrecht, Netherlands
¹²Department of Paediatric Oncology/Haematology, Children's Clinical University Hospital, Riga, Latvia
¹³Department of Pediatrics, Oncology and Hematology, Oslo University Hospital, Oslo, Norway
¹⁴Department of Clinical Sciences, Pediatrics, Umeå University Hospital, Umeå, Sweden
¹⁵Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden
¹⁶Center of Oncology and Hematology, BMT Unit, Vilnius University Children's Hospital, Vilnius, Lithuania
¹⁷Childhood Cancer Center, Skåne University Hospital, Lund, Sweden
¹⁸Department of Hematology Oncology, Tallinn Children´s Hospital, Tallinn, Estonia
¹⁹Department of Hematology, Aarhus University Hospital, Aarhus, Denmark

Camilla Poulsen, BS^1*, Kristian Juul Sandahl, MD^2*, Lene Karlsson^3*, Jonas Abrahamsson, MD, PhD, Professor^3*, Nira Arad-Cohen^4*, Daniel Cheuk^5*, Barbara De Moerloose, MD^6*, Jose Maria Fernandez Navarro^7*, Kirsi Jahnukainen^8*, Gertjan J.L. Kaspers, MD, PhD⁹, Zhanna Kovalova^10*, Monica Cheng Munthe-Kaas^11*, Ulrika Norén-Nyström^12*, Josefine Palle^13*, Ramune Pasauliene^14*, Cornelis Jan Pronk, MD, PhD^15*, Kadri Saks^16*, Kristian Juul-Dam, MD^2* and Henrik Hasle²

¹Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus N, AL, Denmark
²Department of Pediatrics and Adolescent Medicine, Aarhus University Hospital, Aarhus, Denmark
³Department of Pediatrics, Institution for Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
⁴Department of Pediatric Hemato-Oncology, Rambam Health Care Campus, Haifa, Israel
⁵Department of Pediatrics and Adolescent Medicine, Hong Kong Children's Hospital and Hong Kong Pediatric Hematology and Oncology Study Group (HKPHOSG), Hong Kong, China
⁶Department of Pediatric Hematology-Oncology, Ghent University Hospital, Ghent, Belgium
⁷Department of Pediatric Hemato-Oncology, Hospital Universitario y Politécnico La Fe, Valencia, Spain
⁸New Children's Hospital, Pediatric Research Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
⁹Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands
¹⁰Department of Paediatric Oncology/Haematology, Children's Clinical University Hospital, Riga, Latvia
¹¹Department of Pediatrics, Oncology and Hematology, Oslo University Hospital, Oslo, Norway
¹²Department of Clinical Sciences, Pediatrics, Umeå University, Umea, Sweden
¹³Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden
¹⁴Center of Oncology and Hematology, BMT Unit, Vilnius University Children's Hospital, Vilnius, Lithuania
¹⁵Childhood Cancer Center, Skåne University Hospital, Lund, Sweden
¹⁶Department of Paediatrics, SA Tallinna Lastehaigla, Tallinn, Estonia

Daniel T Peters, MD¹, Deedra Nicolet, MS^2*, Yazan F Madanat, MD³, Jesus D Gonzalez-Lugo, MD⁴, Alexander J. Ambinder, MD, MPH⁵, Onyee Chan, MD^6*, Michael Jamie Hochman, MD⁷, Najla H. Al Ali, Ms^8*, Victoria Klein, MS^2*, Krzysztof Mrózek, MD, PhD², Tara L. Lin, MD⁴, Alice Mims, MD⁹, Charles Foucar, MD¹⁰ and Joshua F. Zeidner, MD¹¹

¹Division of Hematology, University of North Carolina School of Medicine, Chapel Hill, NC
²The Ohio State University Comprehensive Cancer Center, Columbus, OH
³Harold C. Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX
⁴Division of Hematologic Malignancies and Cellular Therapeutics, The University of Kansas Cancer Center, Westwood, KS
⁵Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD
⁶H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁷Emory University Winship Cancer Institute, Atlanta, GA
⁸Department of Malignant Hematology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL
⁹Division of Hematology, The Ohio State University Comprehensive Cancer Center, Columbus, OH
¹⁰University of New Mexico, Ann Arbor, MI
¹¹Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC