-Author name in bold denotes the presenting author
-Asterisk * with author name denotes a Non-ASH member
Clinically Relevant Abstract denotes an abstract that is clinically relevant.

PhD Trainee denotes that this is a recommended PHD Trainee Session.

Ticketed Session denotes that this is a ticketed session.

501.O1.6 501. Hematopoietic Stem and Progenitor Cells and Hematopoiesis: Basic and Translational: Metabolism, Differentiation and Inflammation

Symposia: Hematopoietic Stem and Progenitor Cells and Hematopoiesis: Basic and Translational Program: Oral and Poster Abstracts
Type: Oral
Hematology Disease Topics & Pathways:
Research, Fundamental Science, Translational Research, Bioinformatics, Hematopoiesis, Immune mechanism, Immunology, Adverse Events, Computational biology, Metabolism, Biological Processes, Microbiome, Molecular biology, Technology and Procedures, Study Population, Animal model, Machine learning, Omics technologies
Sunday, December 8, 2024: 9:30 AM-11:00 AM
Room 7 (San Diego Convention Center)
Moderators:
Kenichi Miharada, PhD, Lund University and Stephanie Z Xie, PhD, Princess Margaret Cancer Centre
Disclosures:
No relevant conflicts of interest to declare.
This session delves into novel insights on the regulation of hematopoietic stem and progenitor cells (HSPCs) under both steady-state and stress conditions, with a focus on metabolomic and proteostatic controls, as well as the roles of inflammatory responses.
9:30 AM

Marius Kuelp, PhD1,2,3*, Adrien Jolly, PhD1,3,4*, Tessa Schmachtel, MSc1*, Björn Häupl, PhD1,3,4*, Thomas Oellerich, MD1,3,4*, Halvard Bonig, MD, MA4,5,6 and Michael A. Rieger, PhD1,2,3,4*

1Department of Medicine 2 - Hematology and Oncology, Goethe University Frankfurt, University Hospital, Frankfurt am Main, Germany
2Cardio-Pulmonary Institute, Frankfurt am Main, Germany
3German Cancer Consortium (DKTK), partner site Frankfurt/Mainz, Frankfurt am Main, Germany
4Frankfurt Cancer Institute (FCI), Frankfurt am Main, Germany
5Institute for Transfusion Medicine and Immunohematology, Goethe University Frankfurt, Frankfurt am Main, Germany
6Department of Cellular Therapeutics (GMP), German Red Cross Blood Service BaWü-He, Institute Frankfurt, Frankfurt am Main, Germany

9:45 AM

Shangqin Guo, PhD, Kutay Karatepe*, Bruna Mafra De Faria*, Jian Zhang*, Xinyue Chen* and Anna Eastman*

Yale Stem Cell Center, Yale University, New Haven, CT

10:00 AM

Arushana Amir Maknojia1,2*, Josaura Fernandez-Sanchez, MD3*, Belinda V Candra, BS1,2*, Lila S Nolan, MD4*, Spencer L Redding, BS2*, Ritu Banerjee, MD, PhD5*, Megan Baldridge, MD, PhD6* and Katherine Y. King, MD, PhD2

1Immunology and Microbiology Program, Graduate School of Biomedical Sciences, Baylor College of Medicine, Houston, TX
2Department of Pediatrics, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX
3Hematology-Oncology, Texas Children Hospital, Houston, TX
4Department of Pediatrics, Division of Newborn Medicine, Wahington University School of Medicine, Saint Louis, MO
5Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN
6Division of Infectious Diseases, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO

10:15 AM

Edward Owusu Kwarteng, PhD, BSc, MSc, Yafeng Li, PhD and Michalis Agathocleous, PhD

Children's Medical Center Research Institute, UT Southwestern Medical Center, Dallas, TX

10:30 AM

QinLu Peng1,2*, Manxi Zheng1,2*, Suxuan Liu2*, Zhejuan Shen2*, Hanqi Liu2*, Xuezhen Ma2*, Zhengyou Yin2*, Yuhan Hu2*, Kaosheng Lv, PhD2*, Qing Li, MD, PhD3*, Yang Mei, PhD4,5* and Lu Liu, PhD1,2,6

1Hunan Provincial Key Laboratory of Animal Models and Molecular Medicine, Changsha, China
2School of Biomedical Sciences, Hunan University, Changsha, China
3Department of Internal Medicine, Division of Hematology/Oncology, University of Michigan, Ann Arbor, MI
4College of Biology, Hunan University, Changsha, China
5The affiliated Xiangtan Central Hospital of Hunan University, Hunan Provincial Key Laboratory of Animal Model and Molecular Medicine, School of Biomedical Sciences, Hunan University, Changsha, China
6The affiliated Xiangtan Central Hospital of Hunan University, Xiangtan, China

10:45 AM

Hui Wang1*, Zhaoru Zhang2*, Yingli Han3*, Weili Zhao4, Penglei Jiang2, Bing Liu5*, Jia Yu6*, Fang Wang7* and Pengxu Qian8*

1Bone Marrow Transplantation Center, the First Affiliated Hospital, Zhejiang University School of Medicine, Zhejiang University, Hangzhou, China
2Institute of Hematology, Zhejiang University, Hangzhou, China
3The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, CHN
4Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China
5State Key Laboratory of Experimental Hematology, Haihe Laboratory of Cell Ecosystem, Institute of Hematology, Fifth Medical Center of Chinese PLA General Hospital, Beijing, CHN
6State Key Laboratory of Common Mechanism Research for Major Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, CHN
7State Key Laboratory of Common Mechanism Research for Major Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, China., Zhengzhou, CHN
8Bone Marrow Transplantation Center, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China

*signifies non-member of ASH